Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2011416965', 'doi': 'https://doi.org/10.1158/1078-0432.ccr-14-0580', 'title': 'Anti-CCR4 Monoclonal Antibody Mogamulizumab for the Treatment of EBV-Associated T- and NK-Cell Lymphoproliferative Diseases', 'display_name': 'Anti-CCR4 Monoclonal Antibody Mogamulizumab for the Treatment of EBV-Associated T- and NK-Cell Lymphoproliferative Diseases', 'publication_year': 2014, 'publication_date': '2014-08-13', 'ids': {'openalex': 'https://openalex.org/W2011416965', 'doi': 'https://doi.org/10.1158/1078-0432.ccr-14-0580', 'mag': '2011416965', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/25117294'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1158/1078-0432.ccr-14-0580', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S183149254', 'display_name': 'Clinical Cancer Research', 'issn_l': '1078-0432', 'issn': ['1078-0432', '1557-3265'], 'is_oa': False, 'is_in_doaj': False, 'is_indexed_in_scopus': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320273', 'host_organization_name': 'American Association for Cancer Research', 'host_organization_lineage': ['https://openalex.org/P4310320273'], 'host_organization_lineage_names': ['American Association for Cancer Research'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://aacr.figshare.com/articles/journal_contribution/Supplementary_Table_1_from_Anti-CCR4_Monoclonal_Antibody_Mogamulizumab_for_the_Treatment_of_EBV-Associated_T-_and_NK-Cell_Lymphoproliferative_Diseases/22460613/1/files/39911910.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5019193594', 'display_name': 'Tetsuhiro Kanazawa', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I60134161', 'display_name': 'Nagoya University', 'ror': 'https://ror.org/04chrp450', 'country_code': 'JP', 'type': 'funder', 'lineage': ['https://openalex.org/I60134161']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Tetsuhiro Kanazawa', 'raw_affiliation_strings': ['1Department of Virology, Nagoya University Graduate School of Medicine, Nagoya, Japan.'], 'affiliations': [{'raw_affiliation_string': '1Department of Virology, Nagoya University Graduate School of Medicine, Nagoya, Japan.', 'institution_ids': ['https://openalex.org/I60134161']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083177198', 'display_name': 'Yutaka Hiramatsu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I60134161', 'display_name': 'Nagoya University', 'ror': 'https://ror.org/04chrp450', 'country_code': 'JP', 'type': 'funder', 'lineage': ['https://openalex.org/I60134161']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yutaka Hiramatsu', 'raw_affiliation_strings': ['1Department of Virology, Nagoya University Graduate School of Medicine, Nagoya, Japan.'], 'affiliations': [{'raw_affiliation_string': '1Department of Virology, Nagoya University Graduate School of Medicine, Nagoya, Japan.', 'institution_ids': ['https://openalex.org/I60134161']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113683223', 'display_name': 'Seiko Iwata', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I60134161', 'display_name': 'Nagoya University', 'ror': 'https://ror.org/04chrp450', 'country_code': 'JP', 'type': 'funder', 'lineage': ['https://openalex.org/I60134161']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Seiko Iwata', 'raw_affiliation_strings': ['1Department of Virology, Nagoya University Graduate School of Medicine, Nagoya, Japan.'], 'affiliations': [{'raw_affiliation_string': '1Department of Virology, Nagoya University Graduate School of Medicine, Nagoya, Japan.', 'institution_ids': ['https://openalex.org/I60134161']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5021387107', 'display_name': 'Mohammed Nure Alam Siddiquey', 'orcid': 'https://orcid.org/0000-0001-8803-3242'}, 'institutions': [{'id': 'https://openalex.org/I60134161', 'display_name': 'Nagoya University', 'ror': 'https://ror.org/04chrp450', 'country_code': 'JP', 'type': 'funder', 'lineage': ['https://openalex.org/I60134161']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Mohammed Siddiquey', 'raw_affiliation_strings': ['1Department of Virology, Nagoya University Graduate School of Medicine, Nagoya, Japan.'], 'affiliations': [{'raw_affiliation_string': '1Department of Virology, Nagoya University Graduate School of Medicine, Nagoya, Japan.', 'institution_ids': ['https://openalex.org/I60134161']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5001746851', 'display_name': 'Yoshitaka Sato', 'orcid': 'https://orcid.org/0000-0002-8541-6413'}, 'institutions': [{'id': 'https://openalex.org/I60134161', 'display_name': 'Nagoya University', 'ror': 'https://ror.org/04chrp450', 'country_code': 'JP', 'type': 'funder', 'lineage': ['https://openalex.org/I60134161']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yoshitaka Sato', 'raw_affiliation_strings': ['1Department of Virology, Nagoya University Graduate School of Medicine, Nagoya, Japan.'], 'affiliations': [{'raw_affiliation_string': '1Department of Virology, Nagoya University Graduate School of Medicine, Nagoya, Japan.', 'institution_ids': ['https://openalex.org/I60134161']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073150594', 'display_name': 'Michio Suzuki', 'orcid': 'https://orcid.org/0000-0001-6150-8957'}, 'institutions': [{'id': 'https://openalex.org/I60134161', 'display_name': 'Nagoya University', 'ror': 'https://ror.org/04chrp450', 'country_code': 'JP', 'type': 'funder', 'lineage': ['https://openalex.org/I60134161']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Michio Suzuki', 'raw_affiliation_strings': ['2Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan.', 'Department of Virology, Nagoya University Graduate School of Medicine, Nagoya, Japan. Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan.'], 'affiliations': [{'raw_affiliation_string': 'Department of Virology, Nagoya University Graduate School of Medicine, Nagoya, Japan. Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan.', 'institution_ids': ['https://openalex.org/I60134161']}, {'raw_affiliation_string': '2Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan.', 'institution_ids': ['https://openalex.org/I60134161']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5052758613', 'display_name': 'Yoshinori Ito', 'orcid': 'https://orcid.org/0000-0001-7199-7088'}, 'institutions': [{'id': 'https://openalex.org/I60134161', 'display_name': 'Nagoya University', 'ror': 'https://ror.org/04chrp450', 'country_code': 'JP', 'type': 'funder', 'lineage': ['https://openalex.org/I60134161']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yoshinori Ito', 'raw_affiliation_strings': ['2Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan.'], 'affiliations': [{'raw_affiliation_string': '2Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan.', 'institution_ids': ['https://openalex.org/I60134161']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5046855564', 'display_name': 'Fumi Goshima', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I60134161', 'display_name': 'Nagoya University', 'ror': 'https://ror.org/04chrp450', 'country_code': 'JP', 'type': 'funder', 'lineage': ['https://openalex.org/I60134161']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Fumi Goshima', 'raw_affiliation_strings': ['1Department of Virology, Nagoya University Graduate School of Medicine, Nagoya, Japan.'], 'affiliations': [{'raw_affiliation_string': '1Department of Virology, Nagoya University Graduate School of Medicine, Nagoya, Japan.', 'institution_ids': ['https://openalex.org/I60134161']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069937286', 'display_name': 'Takayuki Murata', 'orcid': 'https://orcid.org/0000-0001-7228-0839'}, 'institutions': [{'id': 'https://openalex.org/I60134161', 'display_name': 'Nagoya University', 'ror': 'https://ror.org/04chrp450', 'country_code': 'JP', 'type': 'funder', 'lineage': ['https://openalex.org/I60134161']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Takayuki Murata', 'raw_affiliation_strings': ['1Department of Virology, Nagoya University Graduate School of Medicine, Nagoya, Japan.'], 'affiliations': [{'raw_affiliation_string': '1Department of Virology, Nagoya University Graduate School of Medicine, Nagoya, Japan.', 'institution_ids': ['https://openalex.org/I60134161']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5036353568', 'display_name': 'Hiroshi Kimura', 'orcid': 'https://orcid.org/0000-0001-8063-5660'}, 'institutions': [{'id': 'https://openalex.org/I60134161', 'display_name': 'Nagoya University', 'ror': 'https://ror.org/04chrp450', 'country_code': 'JP', 'type': 'funder', 'lineage': ['https://openalex.org/I60134161']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hiroshi Kimura', 'raw_affiliation_strings': ['1Department of Virology, Nagoya University Graduate School of Medicine, Nagoya, Japan.'], 'affiliations': [{'raw_affiliation_string': '1Department of Virology, Nagoya University Graduate School of Medicine, Nagoya, Japan.', 'institution_ids': ['https://openalex.org/I60134161']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.902, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 32, 'citation_normalized_percentile': {'value': 0.928461, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '20', 'issue': '19', 'first_page': '5075', 'last_page': '5084'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10685', 'display_name': 'Viral-associated cancers and disorders', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10685', 'display_name': 'Viral-associated cancers and disorders', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11020', 'display_name': 'Immune Cell Function and Interaction', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10185', 'display_name': 'Lymphoma Diagnosis and Treatment', 'score': 0.9976, 'subfield': {'id': 'https://openalex.org/subfields/2734', 'display_name': 'Pathology and Forensic Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/ccr4', 'display_name': 'CCR4', 'score': 0.71543914}], 'concepts': [{'id': 'https://openalex.org/C40677261', 'wikidata': 'https://www.wikidata.org/wiki/Q21418091', 'display_name': 'Antibody-dependent cell-mediated cytotoxicity', 'level': 4, 'score': 0.85086685}, {'id': 'https://openalex.org/C2775866117', 'wikidata': 'https://www.wikidata.org/wiki/Q21102300', 'display_name': 'CCR4', 'level': 5, 'score': 0.71543914}, {'id': 'https://openalex.org/C542903549', 'wikidata': 'https://www.wikidata.org/wiki/Q422248', 'display_name': 'Monoclonal antibody', 'level': 3, 'score': 0.5394988}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.4939552}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.4187445}, {'id': 'https://openalex.org/C163864487', 'wikidata': 'https://www.wikidata.org/wiki/Q6901461', 'display_name': 'Monoclonal', 'level': 4, 'score': 0.41515076}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.40248296}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.3482301}, {'id': 'https://openalex.org/C13373296', 'wikidata': 'https://www.wikidata.org/wiki/Q421866', 'display_name': 'Chemokine', 'level': 3, 'score': 0.20508653}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.17349035}, {'id': 'https://openalex.org/C12823836', 'wikidata': 'https://www.wikidata.org/wiki/Q24720618', 'display_name': 'Chemokine receptor', 'level': 4, 'score': 0.14598295}], 'mesh': [{'descriptor_ui': 'D061067', 'descriptor_name': 'Antibodies, Monoclonal, Humanized', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D020031', 'descriptor_name': 'Epstein-Barr Virus Infections', 'qualifier_ui': 'Q000150', 'qualifier_name': 'complications', 'is_major_topic': True}, {'descriptor_ui': 'D004854', 'descriptor_name': 'Herpesvirus 4, Human', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D007694', 'descriptor_name': 'Killer Cells, Natural', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D008232', 'descriptor_name': 'Lymphoproliferative Disorders', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': True}, {'descriptor_ui': 'D054398', 'descriptor_name': 'Receptors, CCR4', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': True}, {'descriptor_ui': 'D013601', 'descriptor_name': 'T-Lymphocytes', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D061067', 'descriptor_name': 'Antibodies, Monoclonal, Humanized', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D061067', 'descriptor_name': 'Antibodies, Monoclonal, Humanized', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D000920', 'descriptor_name': 'Antibody-Dependent Cell Cytotoxicity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000920', 'descriptor_name': 'Antibody-Dependent Cell Cytotoxicity', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000970', 'descriptor_name': 'Antineoplastic Agents', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004195', 'descriptor_name': 'Disease Models, Animal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020031', 'descriptor_name': 'Epstein-Barr Virus Infections', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015870', 'descriptor_name': 'Gene Expression', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016130', 'descriptor_name': 'Immunophenotyping', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007694', 'descriptor_name': 'Killer Cells, Natural', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D007694', 'descriptor_name': 'Killer Cells, Natural', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008232', 'descriptor_name': 'Lymphoproliferative Disorders', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D008232', 'descriptor_name': 'Lymphoproliferative Disorders', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D008232', 'descriptor_name': 'Lymphoproliferative Disorders', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008232', 'descriptor_name': 'Lymphoproliferative Disorders', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D054398', 'descriptor_name': 'Receptors, CCR4', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D054398', 'descriptor_name': 'Receptors, CCR4', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D054398', 'descriptor_name': 'Receptors, CCR4', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013601', 'descriptor_name': 'T-Lymphocytes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013601', 'descriptor_name': 'T-Lymphocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D047368', 'descriptor_name': 'Tumor Burden', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D047368', 'descriptor_name': 'Tumor Burden', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D023041', 'descriptor_name': 'Xenograft Model Antitumor Assays', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1158/1078-0432.ccr-14-0580', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S183149254', 'display_name': 'Clinical Cancer Research', 'issn_l': '1078-0432', 'issn': ['1078-0432', '1557-3265'], 'is_oa': False, 'is_in_doaj': False, 'is_indexed_in_scopus': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320273', 'host_organization_name': 'American Association for Cancer Research', 'host_organization_lineage': ['https://openalex.org/P4310320273'], 'host_organization_lineage_names': ['American Association for Cancer Research'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1158/1078-0432.22460613', 'pdf_url': 'https://aacr.figshare.com/articles/journal_contribution/Supplementary_Table_1_from_Anti-CCR4_Monoclonal_Antibody_Mogamulizumab_for_the_Treatment_of_EBV-Associated_T-_and_NK-Cell_Lymphoproliferative_Diseases/22460613/1/files/39911910.pdf', 'source': None, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/25117294', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_indexed_in_scopus': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1158/1078-0432.22460613', 'pdf_url': 'https://aacr.figshare.com/articles/journal_contribution/Supplementary_Table_1_from_Anti-CCR4_Monoclonal_Antibody_Mogamulizumab_for_the_Treatment_of_EBV-Associated_T-_and_NK-Cell_Lymphoproliferative_Diseases/22460613/1/files/39911910.pdf', 'source': None, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.79}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 52, 'referenced_works': ['https://openalex.org/W1519962349', 'https://openalex.org/W1605230984', 'https://openalex.org/W1906100218', 'https://openalex.org/W1966771537', 'https://openalex.org/W1967695968', 'https://openalex.org/W1972253514', 'https://openalex.org/W1977043587', 'https://openalex.org/W1984282453', 'https://openalex.org/W1999625162', 'https://openalex.org/W2004101061', 'https://openalex.org/W2009275715', 'https://openalex.org/W2012769592', 'https://openalex.org/W2024873768', 'https://openalex.org/W2031423829', 'https://openalex.org/W2033447452', 'https://openalex.org/W2035705430', 'https://openalex.org/W2036386987', 'https://openalex.org/W2040352295', 'https://openalex.org/W2040626805', 'https://openalex.org/W2043946207', 'https://openalex.org/W2049609155', 'https://openalex.org/W2051821583', 'https://openalex.org/W2052425622', 'https://openalex.org/W2064565700', 'https://openalex.org/W2073631928', 'https://openalex.org/W2080644148', 'https://openalex.org/W2083329634', 'https://openalex.org/W2094342081', 'https://openalex.org/W2095544028', 'https://openalex.org/W2102113607', 'https://openalex.org/W2103384599', 'https://openalex.org/W2110220145', 'https://openalex.org/W2110890034', 'https://openalex.org/W2118745945', 'https://openalex.org/W2124001536', 'https://openalex.org/W2139792658', 'https://openalex.org/W2143578698', 'https://openalex.org/W2146652141', 'https://openalex.org/W2154227505', 'https://openalex.org/W2162251899', 'https://openalex.org/W2175452743', 'https://openalex.org/W2190936515', 'https://openalex.org/W2203680970', 'https://openalex.org/W2259187199', 'https://openalex.org/W2331216044', 'https://openalex.org/W2500642038', 'https://openalex.org/W2522939951', 'https://openalex.org/W2997623337', 'https://openalex.org/W4241246918', 'https://openalex.org/W4251169518', 'https://openalex.org/W43641330', 'https://openalex.org/W72548863'], 'related_works': ['https://openalex.org/W2366047017', 'https://openalex.org/W2082254397', 'https://openalex.org/W2073840950', 'https://openalex.org/W2067077431', 'https://openalex.org/W2041126185', 'https://openalex.org/W2036403810', 'https://openalex.org/W2009601581', 'https://openalex.org/W2003931060', 'https://openalex.org/W1999686187', 'https://openalex.org/W1971294201'], 'abstract_inverted_index': {'Epstein-Barr': [0], 'virus': [1], '(EBV)': [2], 'infects': [3], 'not': [4], 'only': [5], 'B': [6], 'cells': [7, 11, 55, 91, 113, 171, 205, 225], 'but': [8], 'also': [9], 'T': [10, 52, 136], 'and': [12, 17, 19, 56, 137, 152, 214], 'natural': [13], 'killer': [14], '(NK)': [15], 'cells,': [16], 'T-': [18], 'NK-cell': [20, 158], 'lymphoproliferative': [21], 'diseases': [22], '(T/NK-LPD)': [23], 'that': [24, 226, 239], 'are': [25], 'refractory': [26], 'to': [27, 216], 'conventional': [28], 'chemotherapies': [29], 'may': [30, 241], 'develop.': [31], 'To': [32], 'identify': [33], 'a': [34, 58, 103, 161, 192, 209, 243], 'molecular-targeted': [35], 'therapy': [36], 'for': [37, 229], 'EBV-associated': [38, 117, 178, 247], 'T/NK-LPDs,': [39], 'we': [40], 'investigated': [41], 'whether': [42, 57], 'CC': [43], 'chemokine': [44], 'receptor': [45], '4': [46], '(CCR4)': [47], 'was': [48, 64, 67, 109, 131, 167, 182], 'expressed': [49, 168], 'on': [50, 79, 111, 169], 'EBV-infected': [51, 112, 170, 200], 'and/or': [53], 'NK': [54, 138], 'humanized': [59], 'anti-CCR4': [60], 'monoclonal': [61], 'antibody,': [62], 'mogamulizumab,': [63], 'effective.CCR4': [65], 'expression': [66, 108, 130], 'examined': [68, 110], 'in': [69, 84, 133, 160, 172, 184], 'various': [70], 'cell': [71, 80, 139, 150], 'lines.': [72, 140], 'In': [73, 94], 'vitro,': [74], 'the': [75, 85, 96, 121, 154, 196], 'effects': [76, 97, 122], 'of': [77, 87, 98, 123, 156, 174, 186, 199], 'mogamulizumab': [78, 99, 124, 234, 240], 'lines': [81], 'were': [82, 100, 125, 206, 227, 231], 'evaluated': [83, 101, 126], 'presence': [86], 'peripheral': [88], 'blood': [89], 'mononuclear': [90], 'from': [92, 114, 208], 'volunteers.': [93], 'vivo,': [95, 120], 'using': [102, 127], 'murine': [104, 162], 'xenograft': [105, 163], 'model.': [106, 164], 'CCR4': [107, 166, 181, 230], 'patients': [115, 176, 188], 'with': [116, 177, 189, 211], 'T/NK-LPDs.': [118, 179, 248], 'Ex': [119], 'patient': [128, 210], 'lymphocytes.CCR4': [129], 'confirmed': [132], 'most': [134], 'EBV-positive': [135, 157, 203], 'Mogamulizumab': [141], 'induced': [142], 'antibody-dependent': [143, 218], 'cellular': [144], 'cytotoxicity': [145, 220], '(ADCC)': [146, 221], 'activity': [147], 'against': [148, 246], 'CCR4-positive': [149], 'lines,': [151], 'inhibited': [153], 'growth': [155], 'lymphomas': [159], 'Furthermore,': [165], '8': [173], '17': [175], 'Interestingly,': [180], 'positive': [183, 228], '5': [185, 187], 'hydroa': [190, 212], 'vacciniforme,': [191], 'photodermatosis': [193], 'caused': [194], 'by': [195, 233], 'clonal': [197], 'expansion': [198], 'γδT': [201, 204, 224], 'cells.': [202], 'obtained': [207], 'vacciniforme': [213], 'subjected': [215], 'an': [217], 'cell-mediated': [219], 'assay.': [222], 'The': [223], 'killed': [232], 'via': [235], 'ADCC.These': [236], 'results': [237], 'indicate': [238], 'be': [242], 'therapeutic': [244], 'option': [245]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2011416965', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 6}, {'year': 2014, 'cited_by_count': 1}], 'updated_date': '2025-01-25T16:18:58.819474', 'created_date': '2016-06-24'}