Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2011406504', 'doi': 'https://doi.org/10.4161/hv.22129', 'title': 'Clinical trial in healthy malaria-naïve adults to evaluate the safety, tolerability, immunogenicity and efficacy of MuStDO5, a five-gene, sporozoite/hepatic stage<i>Plasmodium falciparum</i>DNA vaccine combined with escalating dose human GM-CSF DNA', 'display_name': 'Clinical trial in healthy malaria-naïve adults to evaluate the safety, tolerability, immunogenicity and efficacy of MuStDO5, a five-gene, sporozoite/hepatic stage<i>Plasmodium falciparum</i>DNA vaccine combined with escalating dose human GM-CSF DNA', 'publication_year': 2012, 'publication_date': '2012-11-16', 'ids': {'openalex': 'https://openalex.org/W2011406504', 'doi': 'https://doi.org/10.4161/hv.22129', 'mag': '2011406504', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/23151451', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3601132'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.4161/hv.22129', 'pdf_url': 'https://www.tandfonline.com/doi/pdf/10.4161/hv.22129?needAccess=true', 'source': {'id': 'https://openalex.org/S2483136528', 'display_name': 'Human Vaccines & Immunotherapeutics', 'issn_l': '2164-5515', 'issn': ['2164-5515', '2164-554X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://www.tandfonline.com/doi/pdf/10.4161/hv.22129?needAccess=true', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5030177021', 'display_name': 'Thomas L. Richie', 'orcid': 'https://orcid.org/0000-0002-2946-5456'}, 'institutions': [{'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Thomas L. Richie', 'raw_affiliation_strings': ['Naval Medical Research Center', 'Silver Spring, MD USA'], 'affiliations': [{'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5012014783', 'display_name': 'Yupin Charoenvit', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Yupin Charoenvit', 'raw_affiliation_strings': ['Naval Medical Research Center', 'Silver Spring, MD USA'], 'affiliations': [{'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100778737', 'display_name': 'Ruobing Wang', 'orcid': 'https://orcid.org/0000-0002-9921-7271'}, 'institutions': [{'id': 'https://openalex.org/I1280259254', 'display_name': 'Henry M. Jackson Foundation', 'ror': 'https://ror.org/04q9tew83', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1280259254']}, {'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ruobing Wang', 'raw_affiliation_strings': ['Bethesda, MD USA', 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'Naval Medical Research Center', 'Silver Spring, MD USA'], 'affiliations': [{'raw_affiliation_string': 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'institution_ids': ['https://openalex.org/I1280259254']}, {'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Bethesda, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048058406', 'display_name': 'Judith E. Epstein', 'orcid': 'https://orcid.org/0000-0001-9381-7607'}, 'institutions': [{'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Judith E. Epstein', 'raw_affiliation_strings': ['Naval Medical Research Center', 'Silver Spring, MD USA'], 'affiliations': [{'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5031668977', 'display_name': 'Richard C. Hedstrom', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Richard C. Hedstrom', 'raw_affiliation_strings': ['Naval Medical Research Center', 'Silver Spring, MD USA'], 'affiliations': [{'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}, {'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5036674077', 'display_name': 'Sanjai Kumar', 'orcid': 'https://orcid.org/0000-0001-6375-9354'}, 'institutions': [{'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}, {'id': 'https://openalex.org/I1280259254', 'display_name': 'Henry M. Jackson Foundation', 'ror': 'https://ror.org/04q9tew83', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1280259254']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Sanjai Kumar', 'raw_affiliation_strings': ['Bethesda, MD USA', 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'Naval Medical Research Center', 'Silver Spring, MD USA'], 'affiliations': [{'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}, {'raw_affiliation_string': 'Bethesda, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'institution_ids': ['https://openalex.org/I1280259254']}, {'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5007698650', 'display_name': 'Thomas Luke', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Thomas C. Luke', 'raw_affiliation_strings': ['Naval Medical Research Center', 'Silver Spring, MD USA'], 'affiliations': [{'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}, {'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5089154408', 'display_name': 'Daniel Freilich', 'orcid': 'https://orcid.org/0000-0002-2219-6900'}, 'institutions': [{'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Daniel A. Freilich', 'raw_affiliation_strings': ['Naval Medical Research Center', 'Silver Spring, MD USA'], 'affiliations': [{'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5112444234', 'display_name': 'João C. Aguiar', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I66804793', 'display_name': 'Pan American Health Organization (Cuba)', 'ror': 'https://ror.org/01p1fe256', 'country_code': 'CU', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210089393', 'https://openalex.org/I4210105654', 'https://openalex.org/I66804793']}], 'countries': ['CU'], 'is_corresponding': False, 'raw_author_name': 'Joao C. Aguiar', 'raw_affiliation_strings': ['Pan American Health Organization', 'Washington, DC USA'], 'affiliations': [{'raw_affiliation_string': 'Washington, DC USA', 'institution_ids': []}, {'raw_affiliation_string': 'Pan American Health Organization', 'institution_ids': ['https://openalex.org/I66804793']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5009799605', 'display_name': 'John B. Sacci', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1280259254', 'display_name': 'Henry M. Jackson Foundation', 'ror': 'https://ror.org/04q9tew83', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1280259254']}, {'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'John B. Sacci, Jr.', 'raw_affiliation_strings': ['Bethesda, MD USA', 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'Naval Medical Research Center', 'Silver Spring, MD USA'], 'affiliations': [{'raw_affiliation_string': 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'institution_ids': ['https://openalex.org/I1280259254']}, {'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Bethesda, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5008513195', 'display_name': 'Martha Sedegah', 'orcid': 'https://orcid.org/0000-0001-6385-508X'}, 'institutions': [{'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Martha Sedegah', 'raw_affiliation_strings': ['Naval Medical Research Center', 'Silver Spring, MD USA'], 'affiliations': [{'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111647691', 'display_name': 'Ronald A. Nosek', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ronald A. Nosek, Jr.', 'raw_affiliation_strings': ['Bethesda, MD USA', 'Naval Medical Research Center'], 'affiliations': [{'raw_affiliation_string': 'Bethesda, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109900972', 'display_name': 'Patricia De La Vega', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}, {'id': 'https://openalex.org/I1280259254', 'display_name': 'Henry M. Jackson Foundation', 'ror': 'https://ror.org/04q9tew83', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1280259254']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Patricia De La Vega', 'raw_affiliation_strings': ['Bethesda, MD USA', 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'Naval Medical Research Center', 'Silver Spring, MD USA'], 'affiliations': [{'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}, {'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Bethesda, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'institution_ids': ['https://openalex.org/I1280259254']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5029210221', 'display_name': 'Mara P. Berzins', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1280259254', 'display_name': 'Henry M. Jackson Foundation', 'ror': 'https://ror.org/04q9tew83', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1280259254']}, {'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Mara P. Berzins', 'raw_affiliation_strings': ['Bethesda, MD USA', 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'Naval Medical Research Center', 'Silver Spring, MD USA'], 'affiliations': [{'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Bethesda, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'institution_ids': ['https://openalex.org/I1280259254']}, {'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5008920781', 'display_name': 'Victoria Majam', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1280259254', 'display_name': 'Henry M. Jackson Foundation', 'ror': 'https://ror.org/04q9tew83', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1280259254']}, {'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Victoria F. Majam', 'raw_affiliation_strings': ['Bethesda, MD USA', 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'Naval Medical Research Center', 'Silver Spring, MD USA'], 'affiliations': [{'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'institution_ids': ['https://openalex.org/I1280259254']}, {'raw_affiliation_string': 'Bethesda, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5085980730', 'display_name': 'Esteban Abot', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1280259254', 'display_name': 'Henry M. Jackson Foundation', 'ror': 'https://ror.org/04q9tew83', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1280259254']}, {'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Esteban N. Abot', 'raw_affiliation_strings': ['Bethesda, MD USA', 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'Naval Medical Research Center', 'Silver Spring, MD USA'], 'affiliations': [{'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Bethesda, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'institution_ids': ['https://openalex.org/I1280259254']}, {'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5112720883', 'display_name': 'Harini Ganeshan', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}, {'id': 'https://openalex.org/I1280259254', 'display_name': 'Henry M. Jackson Foundation', 'ror': 'https://ror.org/04q9tew83', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1280259254']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Harini Ganeshan', 'raw_affiliation_strings': ['Bethesda, MD USA', 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'Naval Medical Research Center', 'Silver Spring, MD USA'], 'affiliations': [{'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}, {'raw_affiliation_string': 'Bethesda, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'institution_ids': ['https://openalex.org/I1280259254']}, {'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5008287102', 'display_name': 'Nancy Richie', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}, {'id': 'https://openalex.org/I1280259254', 'display_name': 'Henry M. Jackson Foundation', 'ror': 'https://ror.org/04q9tew83', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1280259254']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Nancy O. Richie', 'raw_affiliation_strings': ['Bethesda, MD USA', 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'Naval Medical Research Center', 'Silver Spring, MD USA'], 'affiliations': [{'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}, {'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Bethesda, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'institution_ids': ['https://openalex.org/I1280259254']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5066766083', 'display_name': 'Jo Glenna Banania', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1280259254', 'display_name': 'Henry M. Jackson Foundation', 'ror': 'https://ror.org/04q9tew83', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1280259254']}, {'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jo Glenna Banania', 'raw_affiliation_strings': ['Bethesda, MD USA', 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'Naval Medical Research Center', 'Silver Spring, MD USA'], 'affiliations': [{'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Bethesda, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'institution_ids': ['https://openalex.org/I1280259254']}, {'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5052130415', 'display_name': 'Maria Fe B. Baraceros', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1280259254', 'display_name': 'Henry M. Jackson Foundation', 'ror': 'https://ror.org/04q9tew83', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1280259254']}, {'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Maria Fe B. Baraceros', 'raw_affiliation_strings': ['Bethesda, MD USA', 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'Naval Medical Research Center', 'Silver Spring, MD USA'], 'affiliations': [{'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Bethesda, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'institution_ids': ['https://openalex.org/I1280259254']}, {'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5002491323', 'display_name': 'Tanya G. Geter', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1280259254', 'display_name': 'Henry M. Jackson Foundation', 'ror': 'https://ror.org/04q9tew83', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1280259254']}, {'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Tanya G. Geter', 'raw_affiliation_strings': ['Bethesda, MD USA', 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'Naval Medical Research Center', 'Silver Spring, MD USA'], 'affiliations': [{'raw_affiliation_string': 'Bethesda, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'institution_ids': ['https://openalex.org/I1280259254']}, {'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035378884', 'display_name': 'Robin Mere', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210100637', 'display_name': 'Vical (United States)', 'ror': 'https://ror.org/00w230w05', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210100637']}, {'id': 'https://openalex.org/I36258959', 'display_name': 'University of California, San Diego', 'ror': 'https://ror.org/0168r3w48', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I36258959']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Robin Mere', 'raw_affiliation_strings': ['San Diego, CA USA', 'Vical'], 'affiliations': [{'raw_affiliation_string': 'Vical', 'institution_ids': ['https://openalex.org/I4210100637']}, {'raw_affiliation_string': 'San Diego, CA USA', 'institution_ids': ['https://openalex.org/I36258959']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083856723', 'display_name': 'Lolita Bebris', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1280259254', 'display_name': 'Henry M. Jackson Foundation', 'ror': 'https://ror.org/04q9tew83', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1280259254']}, {'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Lolita Bebris', 'raw_affiliation_strings': ['Bethesda, MD USA', 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'Naval Medical Research Center', 'Silver Spring, MD USA'], 'affiliations': [{'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Bethesda, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'institution_ids': ['https://openalex.org/I1280259254']}, {'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5036689148', 'display_name': 'Keith Limbach', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1280259254', 'display_name': 'Henry M. Jackson Foundation', 'ror': 'https://ror.org/04q9tew83', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1280259254']}, {'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Keith Limbach', 'raw_affiliation_strings': ['Bethesda, MD USA', 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'Naval Medical Research Center', 'Silver Spring, MD USA'], 'affiliations': [{'raw_affiliation_string': 'Bethesda, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'institution_ids': ['https://openalex.org/I1280259254']}, {'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5019444273', 'display_name': 'Bradley Hickey', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Bradley W. Hickey', 'raw_affiliation_strings': ['Naval Medical Research Center', 'Silver Spring, MD USA'], 'affiliations': [{'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}, {'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5014264036', 'display_name': 'David E. Lanar', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I92664306', 'display_name': 'Walter Reed Army Institute of Research', 'ror': 'https://ror.org/0145znz58', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I106965489', 'https://openalex.org/I1304082316', 'https://openalex.org/I1330347796', 'https://openalex.org/I2802581893', 'https://openalex.org/I4210088792', 'https://openalex.org/I92664306']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'David E. Lanar', 'raw_affiliation_strings': ['Silver Spring, MD USA', 'Walter Reed Army Institute of Research'], 'affiliations': [{'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Walter Reed Army Institute of Research', 'institution_ids': ['https://openalex.org/I92664306']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103513637', 'display_name': 'Jennifer Ng', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1318116459', 'display_name': 'National Marrow Donor Program', 'ror': 'https://ror.org/016cke005', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1318116459']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jennifer Ng', 'raw_affiliation_strings': ['C.W. Bill Young Department of Defense Marrow Donor Program', 'Rockville, MD USA'], 'affiliations': [{'raw_affiliation_string': 'C.W. Bill Young Department of Defense Marrow Donor Program', 'institution_ids': ['https://openalex.org/I1318116459']}, {'raw_affiliation_string': 'Rockville, MD USA', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5060426989', 'display_name': 'Meng Shi', 'orcid': 'https://orcid.org/0000-0002-8119-9757'}, 'institutions': [{'id': 'https://openalex.org/I92664306', 'display_name': 'Walter Reed Army Institute of Research', 'ror': 'https://ror.org/0145znz58', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I106965489', 'https://openalex.org/I1304082316', 'https://openalex.org/I1330347796', 'https://openalex.org/I2802581893', 'https://openalex.org/I4210088792', 'https://openalex.org/I92664306']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Meng Shi', 'raw_affiliation_strings': ['Silver Spring, MD USA', 'Walter Reed Army Institute of Research'], 'affiliations': [{'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Walter Reed Army Institute of Research', 'institution_ids': ['https://openalex.org/I92664306']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042125372', 'display_name': 'Peter Hobart', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210100637', 'display_name': 'Vical (United States)', 'ror': 'https://ror.org/00w230w05', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210100637']}, {'id': 'https://openalex.org/I36258959', 'display_name': 'University of California, San Diego', 'ror': 'https://ror.org/0168r3w48', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I36258959']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Peter M. Hobart', 'raw_affiliation_strings': ['San Diego, CA USA', 'Vical'], 'affiliations': [{'raw_affiliation_string': 'Vical', 'institution_ids': ['https://openalex.org/I4210100637']}, {'raw_affiliation_string': 'San Diego, CA USA', 'institution_ids': ['https://openalex.org/I36258959']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5086799430', 'display_name': 'Jon Norman', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210100637', 'display_name': 'Vical (United States)', 'ror': 'https://ror.org/00w230w05', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210100637']}, {'id': 'https://openalex.org/I36258959', 'display_name': 'University of California, San Diego', 'ror': 'https://ror.org/0168r3w48', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I36258959']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jon A. Norman', 'raw_affiliation_strings': ['San Diego, CA USA', 'Vical'], 'affiliations': [{'raw_affiliation_string': 'Vical', 'institution_ids': ['https://openalex.org/I4210100637']}, {'raw_affiliation_string': 'San Diego, CA USA', 'institution_ids': ['https://openalex.org/I36258959']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000754492', 'display_name': 'Lorraine Soisson', 'orcid': None}, 'institutions': [], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Lorraine A. Soisson', 'raw_affiliation_strings': ['USAID', 'Washington, DC USA'], 'affiliations': [{'raw_affiliation_string': 'Washington, DC USA', 'institution_ids': []}, {'raw_affiliation_string': 'USAID', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063342340', 'display_name': 'Michael R. Hollingdale', 'orcid': 'https://orcid.org/0000-0002-2343-3824'}, 'institutions': [{'id': 'https://openalex.org/I1280259254', 'display_name': 'Henry M. Jackson Foundation', 'ror': 'https://ror.org/04q9tew83', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1280259254']}, {'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Michael R. Hollingdale', 'raw_affiliation_strings': ['Bethesda, MD USA', 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'Naval Medical Research Center', 'Silver Spring, MD USA'], 'affiliations': [{'raw_affiliation_string': 'Bethesda, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Henry M. Jackson Foundation for the Advancement of Military Medicine', 'institution_ids': ['https://openalex.org/I1280259254']}, {'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5055537743', 'display_name': 'William O. Rogers', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'William O. Rogers', 'raw_affiliation_strings': ['Naval Medical Research Center', 'Silver Spring, MD USA'], 'affiliations': [{'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5087303099', 'display_name': 'Denise L. Doolan', 'orcid': 'https://orcid.org/0000-0001-7354-8817'}, 'institutions': [{'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Denise L. Doolan', 'raw_affiliation_strings': ['Naval Medical Research Center', 'Silver Spring, MD USA'], 'affiliations': [{'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5000295555', 'display_name': 'Stephen L. Hoffman', 'orcid': 'https://orcid.org/0000-0002-0700-9505'}, 'institutions': [{'id': 'https://openalex.org/I1312537475', 'display_name': 'Naval Medical Research Command', 'ror': 'https://ror.org/05f421b09', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1312537475', 'https://openalex.org/I1330347796', 'https://openalex.org/I3130687028', 'https://openalex.org/I4399598358']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Stephen L. Hoffman', 'raw_affiliation_strings': ['Naval Medical Research Center', 'Silver Spring, MD USA'], 'affiliations': [{'raw_affiliation_string': 'Silver Spring, MD USA', 'institution_ids': []}, {'raw_affiliation_string': 'Naval Medical Research Center', 'institution_ids': ['https://openalex.org/I1312537475']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 7, 'corresponding_author_ids': ['https://openalex.org/A5030177021'], 'corresponding_institution_ids': ['https://openalex.org/I1312537475'], 'apc_list': {'value': 2895, 'currency': 'EUR', 'value_usd': 3175, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 5.373, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 47, 'citation_normalized_percentile': {'value': 0.917541, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '8', 'issue': '11', 'first_page': '1564', 'last_page': '1584'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10091', 'display_name': 'Malaria Research and Control', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10091', 'display_name': 'Malaria Research and Control', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12576', 'display_name': 'vaccines and immunoinformatics approaches', 'score': 0.9959, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10112', 'display_name': 'HIV Research and Treatment', 'score': 0.9935, 'subfield': {'id': 'https://openalex.org/subfields/2406', 'display_name': 'Virology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/circumsporozoite-protein', 'display_name': 'Circumsporozoite protein', 'score': 0.8345833}], 'concepts': [{'id': 'https://openalex.org/C2781074509', 'wikidata': 'https://www.wikidata.org/wiki/Q24778282', 'display_name': 'Circumsporozoite protein', 'level': 4, 'score': 0.8345833}, {'id': 'https://openalex.org/C2780868878', 'wikidata': 'https://www.wikidata.org/wiki/Q1660197', 'display_name': 'Immunogenicity', 'level': 3, 'score': 0.74563825}, {'id': 'https://openalex.org/C167508917', 'wikidata': 'https://www.wikidata.org/wiki/Q578537', 'display_name': 'DNA vaccination', 'level': 4, 'score': 0.7016995}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.69696516}, {'id': 'https://openalex.org/C2778371730', 'wikidata': 'https://www.wikidata.org/wiki/Q311383', 'display_name': 'Plasmodium falciparum', 'level': 3, 'score': 0.6337032}, {'id': 'https://openalex.org/C2781034427', 'wikidata': 'https://www.wikidata.org/wiki/Q6741353', 'display_name': 'Malaria vaccine', 'level': 4, 'score': 0.5868022}, {'id': 'https://openalex.org/C2778048844', 'wikidata': 'https://www.wikidata.org/wiki/Q12156', 'display_name': 'Malaria', 'level': 2, 'score': 0.57004595}, {'id': 'https://openalex.org/C147483822', 'wikidata': 'https://www.wikidata.org/wiki/Q103537', 'display_name': 'Antigen', 'level': 2, 'score': 0.5532769}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.54131746}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5019984}, {'id': 'https://openalex.org/C22744801', 'wikidata': 'https://www.wikidata.org/wiki/Q172778', 'display_name': 'Plasmid', 'level': 3, 'score': 0.46142796}, {'id': 'https://openalex.org/C22070199', 'wikidata': 'https://www.wikidata.org/wiki/Q192995', 'display_name': 'Vaccination', 'level': 2, 'score': 0.4165046}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.4075975}, {'id': 'https://openalex.org/C2780801004', 'wikidata': 'https://www.wikidata.org/wiki/Q1415366', 'display_name': 'Immunization', 'level': 3, 'score': 0.2817882}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.12132469}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000953', 'descriptor_name': 'Antigens, Protozoan', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D016178', 'descriptor_name': 'Granulocyte-Macrophage Colony-Stimulating Factor', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D017780', 'descriptor_name': 'Malaria Vaccines', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D017780', 'descriptor_name': 'Malaria Vaccines', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': 'Q000472', 'qualifier_name': 'pathogenicity', 'is_major_topic': True}, {'descriptor_ui': 'D034101', 'descriptor_name': 'Sporozoites', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D019444', 'descriptor_name': 'Vaccines, DNA', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D019444', 'descriptor_name': 'Vaccines, DNA', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000953', 'descriptor_name': 'Antigens, Protozoan', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016178', 'descriptor_name': 'Granulocyte-Macrophage Colony-Stimulating Factor', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D016178', 'descriptor_name': 'Granulocyte-Macrophage Colony-Stimulating Factor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017780', 'descriptor_name': 'Malaria Vaccines', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D017780', 'descriptor_name': 'Malaria Vaccines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010957', 'descriptor_name': 'Plasmids', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D010957', 'descriptor_name': 'Plasmids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010963', 'descriptor_name': 'Plasmodium falciparum', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D034101', 'descriptor_name': 'Sporozoites', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019444', 'descriptor_name': 'Vaccines, DNA', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D019444', 'descriptor_name': 'Vaccines, DNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055815', 'descriptor_name': 'Young Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.4161/hv.22129', 'pdf_url': 'https://www.tandfonline.com/doi/pdf/10.4161/hv.22129?needAccess=true', 'source': {'id': 'https://openalex.org/S2483136528', 'display_name': 'Human Vaccines & Immunotherapeutics', 'issn_l': '2164-5515', 'issn': ['2164-5515', '2164-554X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3601132', 'pdf_url': 'https://europepmc.org/articles/pmc3601132?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601132', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/23151451', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.4161/hv.22129', 'pdf_url': 'https://www.tandfonline.com/doi/pdf/10.4161/hv.22129?needAccess=true', 'source': {'id': 'https://openalex.org/S2483136528', 'display_name': 'Human Vaccines & Immunotherapeutics', 'issn_l': '2164-5515', 'issn': ['2164-5515', '2164-554X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.85, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 95, 'referenced_works': ['https://openalex.org/W100984399', 'https://openalex.org/W1500666082', 'https://openalex.org/W1509305962', 'https://openalex.org/W1509801916', 'https://openalex.org/W1511568058', 'https://openalex.org/W1557000134', 'https://openalex.org/W1935940544', 'https://openalex.org/W1965501933', 'https://openalex.org/W1970855368', 'https://openalex.org/W1973378073', 'https://openalex.org/W1981252506', 'https://openalex.org/W1982617641', 'https://openalex.org/W1987060667', 'https://openalex.org/W1987657194', 'https://openalex.org/W1993111299', 'https://openalex.org/W1995630383', 'https://openalex.org/W1999298446', 'https://openalex.org/W2002288384', 'https://openalex.org/W2002923803', 'https://openalex.org/W2007098121', 'https://openalex.org/W2009446631', 'https://openalex.org/W2011081519', 'https://openalex.org/W2011312797', 'https://openalex.org/W2014595456', 'https://openalex.org/W2016696697', 'https://openalex.org/W2017865185', 'https://openalex.org/W2019313744', 'https://openalex.org/W2020992709', 'https://openalex.org/W2027575466', 'https://openalex.org/W2028265413', 'https://openalex.org/W2029016425', 'https://openalex.org/W2029285142', 'https://openalex.org/W2035638405', 'https://openalex.org/W2035645815', 'https://openalex.org/W2037896435', 'https://openalex.org/W2042352798', 'https://openalex.org/W2042555975', 'https://openalex.org/W2042808979', 'https://openalex.org/W2048666922', 'https://openalex.org/W2052626913', 'https://openalex.org/W2053801470', 'https://openalex.org/W2055364909', 'https://openalex.org/W2060732719', 'https://openalex.org/W2063680739', 'https://openalex.org/W2063926829', 'https://openalex.org/W2065153598', 'https://openalex.org/W2065157516', 'https://openalex.org/W2065795429', 'https://openalex.org/W2065849927', 'https://openalex.org/W2066382515', 'https://openalex.org/W2067423878', 'https://openalex.org/W2067930723', 'https://openalex.org/W2068939504', 'https://openalex.org/W2072621353', 'https://openalex.org/W2072677305', 'https://openalex.org/W2073484977', 'https://openalex.org/W2081139134', 'https://openalex.org/W2082008654', 'https://openalex.org/W2088608170', 'https://openalex.org/W2089442023', 'https://openalex.org/W2090020022', 'https://openalex.org/W2091089019', 'https://openalex.org/W2095554063', 'https://openalex.org/W2096635083', 'https://openalex.org/W2101431448', 'https://openalex.org/W2104360426', 'https://openalex.org/W2108476551', 'https://openalex.org/W2111636254', 'https://openalex.org/W2114643485', 'https://openalex.org/W2117929568', 'https://openalex.org/W2118599971', 'https://openalex.org/W2118887119', 'https://openalex.org/W2119995018', 'https://openalex.org/W2120160125', 'https://openalex.org/W2121290793', 'https://openalex.org/W2122307086', 'https://openalex.org/W2123388095', 'https://openalex.org/W2126344726', 'https://openalex.org/W2126938681', 'https://openalex.org/W2128583825', 'https://openalex.org/W2132042285', 'https://openalex.org/W2136281747', 'https://openalex.org/W2138891368', 'https://openalex.org/W2141792732', 'https://openalex.org/W2144296388', 'https://openalex.org/W2151174052', 'https://openalex.org/W2158376169', 'https://openalex.org/W2162478418', 'https://openalex.org/W2169790609', 'https://openalex.org/W2171869957', 'https://openalex.org/W2174540193', 'https://openalex.org/W2238131148', 'https://openalex.org/W2239593703', 'https://openalex.org/W2333383965', 'https://openalex.org/W4244793869'], 'related_works': ['https://openalex.org/W4389179709', 'https://openalex.org/W4301496719', 'https://openalex.org/W3206150152', 'https://openalex.org/W3134240677', 'https://openalex.org/W2514753441', 'https://openalex.org/W2390379074', 'https://openalex.org/W2313474475', 'https://openalex.org/W2145472004', 'https://openalex.org/W1971842458', 'https://openalex.org/W1965953233'], 'abstract_inverted_index': {'When': [0], 'introduced': [1], 'in': [2, 32, 38, 77], 'the': [3, 34, 65, 69, 72, 203, 222, 243], '1990s,': [4], 'immunization': [5], 'with': [6, 226, 231], 'DNA': [7, 43, 205, 227, 249], 'plasmids': [8, 208, 228], 'was': [9, 172], 'considered': [10], 'potentially': [11], 'revolutionary': [12], 'for': [13, 17, 215, 224, 237], 'vaccine': [14, 63, 171], 'development,': [15], 'particularly': [16], 'vaccines': [18], 'intended': [19], 'to': [20, 209, 241], 'induce': [21], 'protective': [22, 246], 'CD8': [23], 'T': [24, 180, 192, 216], 'cell': [25, 181, 193, 217], 'responses': [26, 183, 194], 'against': [27], 'multiple': [28], 'antigens.': [29], 'We': [30], 'conducted,': [31], '1997-1998,': [33], 'first': [35], 'clinical': [36, 80], 'trial': [37, 81, 201], 'healthy': [39], 'humans': [40], 'of': [41, 68, 82, 110, 113, 125, 138, 248], 'a': [42, 45, 60, 79, 83, 108, 126], 'vaccine,': [44], 'single': [46], 'plasmid': [47, 115, 128], 'encoding': [48, 88, 129], 'Plasmodium': [49], 'falciparum': [50], 'circumsporozoite': [51], 'protein': [52], '(PfCSP),': [53], 'as': [54], 'an': [55, 234], 'initial': [56], 'step': [57], 'toward': [58], 'developing': [59], 'multi-antigen': [61], 'malaria': [62, 160, 198], 'targeting': [64], 'liver': [66], 'stages': [67], 'parasite.': [70], 'As': [71], 'next': [73], 'step,': [74], 'we': [75], 'conducted': [76], '2000-2001': [78], 'five-plasmid': [84], 'mixture': [85, 109], 'called': [86], 'MuStDO5': [87, 204], 'pre-erythrocytic': [89], 'antigens': [90], 'PfCSP,': [91], 'PfSSP2/TRAP,': [92], 'PfEXP1,': [93], 'PfLSA1': [94], 'and': [95, 151, 154, 174, 206, 212, 229, 245], 'PfLSA3.': [96], 'Thirty-two,': [97], 'malaria-naïve,': [98], 'adult': [99], 'volunteers': [100, 189], 'were': [101, 141, 190, 195], 'enrolled': [102], 'sequentially': [103], 'into': [104], 'four': [105], 'cohorts': [106], 'receiving': [107], '500': [111, 123], 'μg': [112], 'each': [114, 139, 155], 'plus': [116], 'escalating': [117], 'doses': [118, 137], '(0,': [119], '20,': [120], '100': [121], 'or': [122], 'μg)': [124], 'sixth': [127], 'human': [130, 159], 'granulocyte': [131], 'macrophage-colony': [132], 'stimulating': [133], 'factor': [134], '(hGM-CSF).': [135], 'Three': [136], 'formulation': [140], 'administered': [142, 162], 'intramuscularly': [143], 'by': [144, 163], 'needle-less': [145], 'jet': [146], 'injection': [147], 'at': [148], '0,': [149], '4': [150], '8': [152], 'weeks,': [153], 'cohort': [156], 'had': [157], 'controlled': [158], 'infection': [161], 'five': [164], 'mosquito': [165], 'bites': [166], '18': [167], 'd': [168], 'later.': [169], 'The': [170], 'safe': [173, 211], 'well-tolerated,': [175], 'inducing': [176], 'moderate': [177], 'antigen-specific,': [178], 'MHC-restricted': [179], 'interferon-γ': [182], 'but': [184], 'no': [185, 188], 'antibodies.': [186], 'Although': [187], 'protected,': [191], 'boosted': [196], 'post': [197], 'challenge.': [199], 'This': [200], 'demonstrated': [202], 'hGM-CSF': [207], 'be': [210], 'modestly': [213], 'immunogenic': [214], 'responses.': [218], 'It': [219], 'also': [220], 'laid': [221], 'foundation': [223], 'priming': [225], 'boosting': [230], 'recombinant': [232], 'viruses,': [233], 'approach': [235], 'known': [236], 'nearly': [238], '15': [239], 'y': [240], 'enhance': [242], 'immunogenicity': [244], 'efficacy': [247], 'vaccines.': [250]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2011406504', 'counts_by_year': [{'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 7}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 5}, {'year': 2016, 'cited_by_count': 4}, {'year': 2015, 'cited_by_count': 9}, {'year': 2014, 'cited_by_count': 6}, {'year': 2013, 'cited_by_count': 4}], 'updated_date': '2024-12-14T04:08:35.324416', 'created_date': '2016-06-24'}