Photopolymerization in Microfluidic Gradient Generators: Microscale Control of Substrate Compliance to Manipulate Cell Response

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Duration: 3 min 30 s
Description: Integration of a microfluidic gradient generator and photopolymerization to fabricate novel hydrogels with tunable mechanical properties on the microscale (see Figure) is reported. This concept introduces a new class of materials that can be used to investigate the role of substrate elastic moduli in controlling cell morphology and cytoskeletal organization, and more generally, cell behavior.
N. Zaari; Padmavathy Rajagopalan; Sehyung Kim; Adam J. Engler; Joyce Wong
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