Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2010448981', 'doi': 'https://doi.org/10.1007/bf01793215', 'title': 'Bradykinin-induced vasodilation is changed to a vasoconstrictor response in vessels of aged normotensive and hypertensive rats', 'display_name': 'Bradykinin-induced vasodilation is changed to a vasoconstrictor response in vessels of aged normotensive and hypertensive rats', 'publication_year': 1995, 'publication_date': '1995-02-01', 'ids': {'openalex': 'https://openalex.org/W2010448981', 'doi': 'https://doi.org/10.1007/bf01793215', 'mag': '2010448981', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/7655987'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/bf01793215', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S55943811', 'display_name': 'Inflammation Research', 'issn_l': '1023-3830', 'issn': ['1023-3830', '1420-908X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5063203815', 'display_name': 'Laura Mantelli', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I45084792', 'display_name': 'University of Florence', 'ror': 'https://ror.org/04jr1s763', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I45084792']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Laura Mantelli', 'raw_affiliation_strings': ['Department of Pharmacology, University of, Florence, Italy.'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology, University of, Florence, Italy.', 'institution_ids': ['https://openalex.org/I45084792']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5043811792', 'display_name': 'S. Amerini', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I45084792', 'display_name': 'University of Florence', 'ror': 'https://ror.org/04jr1s763', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I45084792']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Sandra Amerini', 'raw_affiliation_strings': ['Department of Pharmacology, University of Florence, Firenze, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology, University of Florence, Firenze, Italy', 'institution_ids': ['https://openalex.org/I45084792']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5103383725', 'display_name': 'Fabrizio Ledda', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I45084792', 'display_name': 'University of Florence', 'ror': 'https://ror.org/04jr1s763', 'country_code': 'IT', 'type': 'education', 'lineage': ['https://openalex.org/I45084792']}], 'countries': ['IT'], 'is_corresponding': False, 'raw_author_name': 'Fabrizio Ledda', 'raw_affiliation_strings': ['Department of Pharmacology, University of Florence, Firenze, Italy'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology, University of Florence, Firenze, Italy', 'institution_ids': ['https://openalex.org/I45084792']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3390, 'currency': 'EUR', 'value_usd': 4390, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.599, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 8, 'citation_normalized_percentile': {'value': 0.621629, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 75, 'max': 76}, 'biblio': {'volume': '44', 'issue': '2', 'first_page': '70', 'last_page': '73'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11917', 'display_name': 'Hereditary Angioedema: Molecular Mechanisms and Clinical Management', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11917', 'display_name': 'Hereditary Angioedema: Molecular Mechanisms and Clinical Management', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10155', 'display_name': 'Role of Nitric Oxide in Health and Disease', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11001', 'display_name': 'Renin-Angiotensin System in Cardiovascular Physiology and Pathology', 'score': 0.9978, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/methoxamine', 'display_name': 'Methoxamine', 'score': 0.7147521}, {'id': 'https://openalex.org/keywords/mesenteric-arteries', 'display_name': 'Mesenteric arteries', 'score': 0.49179938}, {'id': 'https://openalex.org/keywords/bradykinin-receptor-antagonist', 'display_name': 'Bradykinin-Receptor Antagonist', 'score': 0.480986}, {'id': 'https://openalex.org/keywords/bradykinin-receptor', 'display_name': 'Bradykinin receptor', 'score': 0.47886512}, {'id': 'https://openalex.org/keywords/kallidin', 'display_name': 'Kallidin', 'score': 0.41446114}], 'concepts': [{'id': 'https://openalex.org/C2779591629', 'wikidata': 'https://www.wikidata.org/wiki/Q24745328', 'display_name': 'Bradykinin', 'level': 3, 'score': 0.9608799}, {'id': 'https://openalex.org/C120770815', 'wikidata': 'https://www.wikidata.org/wiki/Q14859627', 'display_name': 'Vasodilation', 'level': 2, 'score': 0.8198232}, {'id': 'https://openalex.org/C2779961880', 'wikidata': 'https://www.wikidata.org/wiki/Q1067506', 'display_name': 'Vasoconstriction', 'level': 2, 'score': 0.7948514}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.7499092}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.7297739}, {'id': 'https://openalex.org/C2780745239', 'wikidata': 'https://www.wikidata.org/wiki/Q685119', 'display_name': 'Methoxamine', 'level': 4, 'score': 0.7147521}, {'id': 'https://openalex.org/C2780771799', 'wikidata': 'https://www.wikidata.org/wiki/Q109592502', 'display_name': 'Mesenteric arteries', 'level': 3, 'score': 0.49179938}, {'id': 'https://openalex.org/C153939273', 'wikidata': 'https://www.wikidata.org/wiki/Q24721039', 'display_name': 'Bradykinin receptor', 'level': 4, 'score': 0.47886512}, {'id': 'https://openalex.org/C2776885963', 'wikidata': 'https://www.wikidata.org/wiki/Q245204', 'display_name': 'Antagonist', 'level': 3, 'score': 0.4788049}, {'id': 'https://openalex.org/C2778122271', 'wikidata': 'https://www.wikidata.org/wiki/Q410943', 'display_name': 'Receptor antagonist', 'level': 4, 'score': 0.46174935}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.44911915}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.44685346}, {'id': 'https://openalex.org/C2779730486', 'wikidata': 'https://www.wikidata.org/wiki/Q2398786', 'display_name': 'Kallidin', 'level': 5, 'score': 0.41446114}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.38605347}, {'id': 'https://openalex.org/C2778938600', 'wikidata': 'https://www.wikidata.org/wiki/Q389934', 'display_name': 'Agonist', 'level': 3, 'score': 0.29238772}, {'id': 'https://openalex.org/C2776246183', 'wikidata': 'https://www.wikidata.org/wiki/Q421924', 'display_name': 'Kinin', 'level': 4, 'score': 0.23315412}, {'id': 'https://openalex.org/C2776820930', 'wikidata': 'https://www.wikidata.org/wiki/Q9655', 'display_name': 'Artery', 'level': 2, 'score': 0.09580091}], 'mesh': [{'descriptor_ui': 'D001920', 'descriptor_name': 'Bradykinin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D006973', 'descriptor_name': 'Hypertension', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': True}, {'descriptor_ui': 'D009131', 'descriptor_name': 'Muscle, Smooth, Vascular', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D014661', 'descriptor_name': 'Vasoconstriction', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D014664', 'descriptor_name': 'Vasodilation', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D000375', 'descriptor_name': 'Aging', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000375', 'descriptor_name': 'Aging', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001920', 'descriptor_name': 'Bradykinin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004195', 'descriptor_name': 'Disease Models, Animal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004730', 'descriptor_name': 'Endothelium, Vascular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004730', 'descriptor_name': 'Endothelium, Vascular', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D006973', 'descriptor_name': 'Hypertension', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008638', 'descriptor_name': 'Mesenteric Arteries', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008638', 'descriptor_name': 'Mesenteric Arteries', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008638', 'descriptor_name': 'Mesenteric Arteries', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D008729', 'descriptor_name': 'Methoxamine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008729', 'descriptor_name': 'Methoxamine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D009119', 'descriptor_name': 'Muscle Contraction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009119', 'descriptor_name': 'Muscle Contraction', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D009126', 'descriptor_name': 'Muscle Relaxation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009126', 'descriptor_name': 'Muscle Relaxation', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D009131', 'descriptor_name': 'Muscle, Smooth, Vascular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011918', 'descriptor_name': 'Rats, Inbred SHR', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011921', 'descriptor_name': 'Rats, Inbred WKY', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014661', 'descriptor_name': 'Vasoconstriction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014664', 'descriptor_name': 'Vasodilation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/bf01793215', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S55943811', 'display_name': 'Inflammation Research', 'issn_l': '1023-3830', 'issn': ['1023-3830', '1420-908X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/7655987', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.53, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 19, 'referenced_works': ['https://openalex.org/W1862226004', 'https://openalex.org/W1925704923', 'https://openalex.org/W1966637576', 'https://openalex.org/W1969298539', 'https://openalex.org/W1976146648', 'https://openalex.org/W1979316500', 'https://openalex.org/W1991983815', 'https://openalex.org/W2015072603', 'https://openalex.org/W2023306174', 'https://openalex.org/W2038970210', 'https://openalex.org/W2044314667', 'https://openalex.org/W2058533505', 'https://openalex.org/W2066722460', 'https://openalex.org/W2078347277', 'https://openalex.org/W2154322752', 'https://openalex.org/W2179910332', 'https://openalex.org/W2409714619', 'https://openalex.org/W2416417233', 'https://openalex.org/W2429985805'], 'related_works': ['https://openalex.org/W71503052', 'https://openalex.org/W3202327181', 'https://openalex.org/W2078361492', 'https://openalex.org/W2063646485', 'https://openalex.org/W2050933961', 'https://openalex.org/W2031892072', 'https://openalex.org/W2030198885', 'https://openalex.org/W2015489274', 'https://openalex.org/W1966505948', 'https://openalex.org/W1565137730'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2010448981', 'counts_by_year': [{'year': 2020, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}], 'updated_date': '2024-08-15T06:51:45.444936', 'created_date': '2016-06-24'}