Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2010006410', 'doi': 'https://doi.org/10.1021/tx9003787', 'title': 'Toxicology of Autoimmune Diseases', 'display_name': 'Toxicology of Autoimmune Diseases', 'publication_year': 2010, 'publication_date': '2010-01-15', 'ids': {'openalex': 'https://openalex.org/W2010006410', 'doi': 'https://doi.org/10.1021/tx9003787', 'mag': '2010006410', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/20078109', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3076021'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/tx9003787', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S152840809', 'display_name': 'Chemical Research in Toxicology', 'issn_l': '0893-228X', 'issn': ['0893-228X', '1520-5010'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://europepmc.org/articles/pmc3076021?pdf=render', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5013388675', 'display_name': 'K. Michael Pollard', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I123431417', 'display_name': 'Scripps Research Institute', 'ror': 'https://ror.org/02dxx6824', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I123431417']}, {'id': 'https://openalex.org/I102134673', 'display_name': 'Linköping University', 'ror': 'https://ror.org/05ynxx418', 'country_code': 'SE', 'type': 'education', 'lineage': ['https://openalex.org/I102134673']}], 'countries': ['SE', 'US'], 'is_corresponding': False, 'raw_author_name': 'K. Michael Pollard', 'raw_affiliation_strings': ['Department of Molecular and Experimental Medicine and Department of Immunology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California, 92037, and Molecular and Immunological Pathology, Department of Clinical and Experimental Medicine, Linköping University, SE-581 85 Linköping, Sweden'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular and Experimental Medicine and Department of Immunology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California, 92037, and Molecular and Immunological Pathology, Department of Clinical and Experimental Medicine, Linköping University, SE-581 85 Linköping, Sweden', 'institution_ids': ['https://openalex.org/I123431417', 'https://openalex.org/I102134673']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083387079', 'display_name': 'Per Hultman', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I123431417', 'display_name': 'Scripps Research Institute', 'ror': 'https://ror.org/02dxx6824', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I123431417']}, {'id': 'https://openalex.org/I102134673', 'display_name': 'Linköping University', 'ror': 'https://ror.org/05ynxx418', 'country_code': 'SE', 'type': 'education', 'lineage': ['https://openalex.org/I102134673']}], 'countries': ['SE', 'US'], 'is_corresponding': False, 'raw_author_name': 'Per Hultman', 'raw_affiliation_strings': ['Department of Molecular and Experimental Medicine and Department of Immunology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California, 92037, and Molecular and Immunological Pathology, Department of Clinical and Experimental Medicine, Linköping University, SE-581 85 Linköping, Sweden'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular and Experimental Medicine and Department of Immunology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California, 92037, and Molecular and Immunological Pathology, Department of Clinical and Experimental Medicine, Linköping University, SE-581 85 Linköping, Sweden', 'institution_ids': ['https://openalex.org/I123431417', 'https://openalex.org/I102134673']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5038738015', 'display_name': 'Dwight H. Kono', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I123431417', 'display_name': 'Scripps Research Institute', 'ror': 'https://ror.org/02dxx6824', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I123431417']}, {'id': 'https://openalex.org/I102134673', 'display_name': 'Linköping University', 'ror': 'https://ror.org/05ynxx418', 'country_code': 'SE', 'type': 'education', 'lineage': ['https://openalex.org/I102134673']}], 'countries': ['SE', 'US'], 'is_corresponding': False, 'raw_author_name': 'Dwight H. Kono', 'raw_affiliation_strings': ['Department of Molecular and Experimental Medicine and Department of Immunology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California, 92037, and Molecular and Immunological Pathology, Department of Clinical and Experimental Medicine, Linköping University, SE-581 85 Linköping, Sweden'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular and Experimental Medicine and Department of Immunology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California, 92037, and Molecular and Immunological Pathology, Department of Clinical and Experimental Medicine, Linköping University, SE-581 85 Linköping, Sweden', 'institution_ids': ['https://openalex.org/I123431417', 'https://openalex.org/I102134673']}]}], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.944, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 105, 'citation_normalized_percentile': {'value': 0.998892, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '23', 'issue': '3', 'first_page': '455', 'last_page': '466'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10031', 'display_name': 'Regulatory T Cell Development and Function', 'score': 0.9901, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10031', 'display_name': 'Regulatory T Cell Development and Function', 'score': 0.9901, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11016', 'display_name': 'Therapeutic Antibodies: Development, Engineering, and Applications', 'score': 0.988, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12438', 'display_name': 'Diagnosis and Management of Urticaria', 'score': 0.9859, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/autoimmunity', 'display_name': 'Autoimmunity', 'score': 0.533612}], 'concepts': [{'id': 'https://openalex.org/C2780130043', 'wikidata': 'https://www.wikidata.org/wiki/Q192360', 'display_name': 'Autoimmunity', 'level': 3, 'score': 0.91387284}, {'id': 'https://openalex.org/C2779075594', 'wikidata': 'https://www.wikidata.org/wiki/Q8084905', 'display_name': 'Autoimmune disease', 'level': 3, 'score': 0.66961277}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.62806463}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.5670005}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.47810835}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.37246376}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.34288436}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.31982407}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.13729396}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.08102679}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001327', 'descriptor_name': 'Autoimmune Diseases', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': True}, {'descriptor_ui': 'D015551', 'descriptor_name': 'Autoimmunity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D064420', 'descriptor_name': 'Drug-Related Side Effects and Adverse Reactions', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001327', 'descriptor_name': 'Autoimmune Diseases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015551', 'descriptor_name': 'Autoimmunity', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/tx9003787', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S152840809', 'display_name': 'Chemical Research in Toxicology', 'issn_l': '0893-228X', 'issn': ['0893-228X', '1520-5010'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3076021', 'pdf_url': 'https://europepmc.org/articles/pmc3076021?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076021', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/20078109', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3076021', 'pdf_url': 'https://europepmc.org/articles/pmc3076021?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.57}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 174, 'referenced_works': ['https://openalex.org/W1483123148', 'https://openalex.org/W1495738289', 'https://openalex.org/W1520041405', 'https://openalex.org/W1552738427', 'https://openalex.org/W1553780195', 'https://openalex.org/W1570853396', 'https://openalex.org/W1571100576', 'https://openalex.org/W1579308580', 'https://openalex.org/W1579365433', 'https://openalex.org/W1582179599', 'https://openalex.org/W1584829149', 'https://openalex.org/W1593209859', 'https://openalex.org/W1594686929', 'https://openalex.org/W1597232807', 'https://openalex.org/W1597917303', 'https://openalex.org/W1598052190', 'https://openalex.org/W178395831', 'https://openalex.org/W1817131636', 'https://openalex.org/W1823692109', 'https://openalex.org/W1873190980', 'https://openalex.org/W1877033574', 'https://openalex.org/W1903998424', 'https://openalex.org/W1917459560', 'https://openalex.org/W1924968745', 'https://openalex.org/W1925369730', 'https://openalex.org/W1964614975', 'https://openalex.org/W1965692028', 'https://openalex.org/W1971951944', 'https://openalex.org/W1972999255', 'https://openalex.org/W1973468400', 'https://openalex.org/W1973698068', 'https://openalex.org/W1976393897', 'https://openalex.org/W1977496118', 'https://openalex.org/W1977918607', 'https://openalex.org/W1979352555', 'https://openalex.org/W1979378256', 'https://openalex.org/W1979396051', 'https://openalex.org/W1981866304', 'https://openalex.org/W1982577835', 'https://openalex.org/W1983463509', 'https://openalex.org/W1983760843', 'https://openalex.org/W1985709281', 'https://openalex.org/W1986431636', 'https://openalex.org/W1987870096', 'https://openalex.org/W1989743958', 'https://openalex.org/W1991133811', 'https://openalex.org/W1991991054', 'https://openalex.org/W1992147654', 'https://openalex.org/W1993652636', 'https://openalex.org/W1993833610', 'https://openalex.org/W1993866665', 'https://openalex.org/W1994900790', 'https://openalex.org/W2003028807', 'https://openalex.org/W2003720716', 'https://openalex.org/W2004522121', 'https://openalex.org/W2006354480', 'https://openalex.org/W2008981940', 'https://openalex.org/W2009004909', 'https://openalex.org/W2011291004', 'https://openalex.org/W2011503659', 'https://openalex.org/W2013281032', 'https://openalex.org/W2015158975', 'https://openalex.org/W2015609638', 'https://openalex.org/W2018957278', 'https://openalex.org/W2020805310', 'https://openalex.org/W2023677727', 'https://openalex.org/W2024672247', 'https://openalex.org/W2024828634', 'https://openalex.org/W2025208802', 'https://openalex.org/W2031575957', 'https://openalex.org/W2031752787', 'https://openalex.org/W2032396159', 'https://openalex.org/W2035383711', 'https://openalex.org/W2035888226', 'https://openalex.org/W2037482308', 'https://openalex.org/W2040006797', 'https://openalex.org/W2040572620', 'https://openalex.org/W2041080344', 'https://openalex.org/W2041608610', 'https://openalex.org/W2042310047', 'https://openalex.org/W2044353844', 'https://openalex.org/W2045006513', 'https://openalex.org/W2045289862', 'https://openalex.org/W2045960416', 'https://openalex.org/W2047863784', 'https://openalex.org/W2048157994', 'https://openalex.org/W2048676348', 'https://openalex.org/W2050224527', 'https://openalex.org/W2050870561', 'https://openalex.org/W2053690838', 'https://openalex.org/W2054378219', 'https://openalex.org/W2054688118', 'https://openalex.org/W2056554727', 'https://openalex.org/W2060304206', 'https://openalex.org/W2060654709', 'https://openalex.org/W2063145176', 'https://openalex.org/W2063551775', 'https://openalex.org/W2066270351', 'https://openalex.org/W2067038440', 'https://openalex.org/W2067075960', 'https://openalex.org/W2067384722', 'https://openalex.org/W2068447357', 'https://openalex.org/W2069008800', 'https://openalex.org/W2072054857', 'https://openalex.org/W2072274986', 'https://openalex.org/W2074292775', 'https://openalex.org/W2078842991', 'https://openalex.org/W2079757802', 'https://openalex.org/W2083618032', 'https://openalex.org/W2084419632', 'https://openalex.org/W2084792231', 'https://openalex.org/W2086865909', 'https://openalex.org/W2087046527', 'https://openalex.org/W2089673252', 'https://openalex.org/W2090431102', 'https://openalex.org/W2090485310', 'https://openalex.org/W2090920523', 'https://openalex.org/W2091800375', 'https://openalex.org/W2092240723', 'https://openalex.org/W2095231192', 'https://openalex.org/W2095565628', 'https://openalex.org/W2101964024', 'https://openalex.org/W2104741056', 'https://openalex.org/W2105439871', 'https://openalex.org/W2106364495', 'https://openalex.org/W2112100627', 'https://openalex.org/W2116184472', 'https://openalex.org/W2116504259', 'https://openalex.org/W2116650911', 'https://openalex.org/W2119731667', 'https://openalex.org/W2120071583', 'https://openalex.org/W2120465956', 'https://openalex.org/W2123095447', 'https://openalex.org/W2123343983', 'https://openalex.org/W2124050692', 'https://openalex.org/W2126384811', 'https://openalex.org/W2126969925', 'https://openalex.org/W2127679449', 'https://openalex.org/W2129956201', 'https://openalex.org/W2133680671', 'https://openalex.org/W2133795774', 'https://openalex.org/W2134341159', 'https://openalex.org/W2138896366', 'https://openalex.org/W2139620102', 'https://openalex.org/W2140354119', 'https://openalex.org/W2142283642', 'https://openalex.org/W2142360671', 'https://openalex.org/W2143902626', 'https://openalex.org/W2145670359', 'https://openalex.org/W2147181840', 'https://openalex.org/W2147878363', 'https://openalex.org/W2147954626', 'https://openalex.org/W2151131523', 'https://openalex.org/W2152402108', 'https://openalex.org/W2160940255', 'https://openalex.org/W2161642462', 'https://openalex.org/W2162607696', 'https://openalex.org/W2163856919', 'https://openalex.org/W2170361690', 'https://openalex.org/W2303200129', 'https://openalex.org/W2319734643', 'https://openalex.org/W2397052163', 'https://openalex.org/W2397299408', 'https://openalex.org/W2399874549', 'https://openalex.org/W2401851121', 'https://openalex.org/W2403795371', 'https://openalex.org/W2413720359', 'https://openalex.org/W2417728688', 'https://openalex.org/W2440540081', 'https://openalex.org/W3191958158', 'https://openalex.org/W4210962292', 'https://openalex.org/W4232229546', 'https://openalex.org/W4313341280', 'https://openalex.org/W4313379035'], 'related_works': ['https://openalex.org/W2409178111', 'https://openalex.org/W2164255384', 'https://openalex.org/W2159145146', 'https://openalex.org/W2158467197', 'https://openalex.org/W2125248743', 'https://openalex.org/W2109923158', 'https://openalex.org/W2101818249', 'https://openalex.org/W2035979324', 'https://openalex.org/W2003720716', 'https://openalex.org/W161285251'], 'abstract_inverted_index': {'Susceptibility': [0], 'to': [1, 49, 99], 'most': [2, 94], 'autoimmune': [3, 23, 101, 108], 'diseases': [4], 'is': [5, 26, 142], 'dependent': [6], 'on': [7, 86], 'polygenic': [8], 'inheritance,': [9], 'environmental': [10, 60], 'factors,': [11, 42, 74], 'and': [12, 37, 46, 77, 138], 'poorly': [13], 'defined': [14], 'stochastic': [15], 'events.': [16], 'One': [17], 'of': [18, 35, 83, 107, 115, 125], 'the': [19, 29, 81], 'significant': [20], 'challenges': [21], 'facing': [22], 'disease': [24, 109], 'research': [25, 116], 'in': [27, 93, 103, 113], 'identifying': [28], 'specific': [30, 119], 'events': [31], 'that': [32], 'trigger': [33], 'loss': [34], 'tolerance': [36], 'autoimmunity.': [38], 'Although': [39, 122], 'many': [40], 'intrinsic': [41], 'including': [43], 'age,': [44], 'sex,': [45], 'genetics,': [47], 'contribute': [48], 'autoimmunity,': [50, 84, 133], 'extrinsic': [51, 73], 'factors': [52, 61], 'such': [53], 'as': [54, 65], 'drugs,': [55], 'chemicals,': [56, 78], 'microbes,': [57], 'or': [58], 'other': [59], 'can': [62, 79], 'also': [63], 'act': [64], 'important': [66], 'initiators.': [67], 'This': [68], 'review': [69], 'explores': [70], 'how': [71], 'certain': [72], 'namely,': [75], 'drugs': [76], 'promote': [80], 'development': [82], 'focusing': [85], 'a': [87, 123, 139], 'few': [88], 'better': [89], 'characterized': [90], 'agents': [91], 'that,': [92], 'instances,': [95], 'have': [96, 128], 'been': [97, 129], 'shown': [98], 'produce': [100], 'manifestations': [102], 'human': [104], 'populations.': [105], 'Mechanisms': [106], 'induction': [110], 'are': [111], 'discussed': [112], 'terms': [114], 'obtained': [117], 'using': [118], 'animal': [120], 'models.': [121], 'number': [124], 'different': [126], 'pathways': [127], 'delineated': [130], 'for': [131], 'drug/chemical-induced': [132], 'some': [134], 'similarities': [135], 'do': [136], 'exist,': [137], 'working': [140], 'model': [141], 'proposed.': [143]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2010006410', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 5}, {'year': 2022, 'cited_by_count': 8}, {'year': 2021, 'cited_by_count': 13}, {'year': 2020, 'cited_by_count': 12}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 5}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 8}, {'year': 2014, 'cited_by_count': 7}, {'year': 2013, 'cited_by_count': 8}, {'year': 2012, 'cited_by_count': 11}], 'updated_date': '2024-09-08T18:35:35.642996', 'created_date': '2016-06-24'}