Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2009925276', 'doi': 'https://doi.org/10.1016/0014-5793(77)80601-7', 'title': 'Activation of rat liver plasma membrane adenylate cyclase by a cytoplasmic protein factor', 'display_name': 'Activation of rat liver plasma membrane adenylate cyclase by a cytoplasmic protein factor', 'publication_year': 1977, 'publication_date': '1977-10-15', 'ids': {'openalex': 'https://openalex.org/W2009925276', 'doi': 'https://doi.org/10.1016/0014-5793(77)80601-7', 'mag': '2009925276', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/913601'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/0014-5793(77)80601-7', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/0014-5793%2877%2980601-7', 'source': {'id': 'https://openalex.org/S104830714', 'display_name': 'FEBS Letters', 'issn_l': '0014-5793', 'issn': ['0014-5793', '1873-3468'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/0014-5793%2877%2980601-7', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5028914156', 'display_name': 'Christine A. Doberska', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I241749', 'display_name': 'University of Cambridge', 'ror': 'https://ror.org/013meh722', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I241749']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Christine A. Doberska', 'raw_affiliation_strings': ['Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW England'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW England', 'institution_ids': ['https://openalex.org/I241749']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5061101747', 'display_name': 'Bronwen Martin', 'orcid': 'https://orcid.org/0000-0002-9185-6925'}, 'institutions': [{'id': 'https://openalex.org/I241749', 'display_name': 'University of Cambridge', 'ror': 'https://ror.org/013meh722', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I241749']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'B.Richard Martin', 'raw_affiliation_strings': ['Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW England'], 'affiliations': [{'raw_affiliation_string': 'Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge, CB2 1QW England', 'institution_ids': ['https://openalex.org/I241749']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3610, 'currency': 'USD', 'value_usd': 3610, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 3.011, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 30, 'citation_normalized_percentile': {'value': 0.647184, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 90, 'max': 91}, 'biblio': {'volume': '82', 'issue': '2', 'first_page': '273', 'last_page': '277'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10617', 'display_name': 'Cellular transport and secretion', 'score': 0.9981, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10617', 'display_name': 'Cellular transport and secretion', 'score': 0.9981, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11150', 'display_name': 'Endoplasmic Reticulum Stress and Disease', 'score': 0.9973, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10602', 'display_name': 'Glycosylation and Glycoproteins Research', 'score': 0.9967, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C180526460', 'wikidata': 'https://www.wikidata.org/wiki/Q356240', 'display_name': 'Adenylate kinase', 'level': 3, 'score': 0.69917715}, {'id': 'https://openalex.org/C2778805511', 'wikidata': 'https://www.wikidata.org/wiki/Q1713', 'display_name': 'Citation', 'level': 2, 'score': 0.6578177}, {'id': 'https://openalex.org/C2780069284', 'wikidata': 'https://www.wikidata.org/wiki/Q5198121', 'display_name': 'Cyclase', 'level': 3, 'score': 0.53748405}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.39523745}, {'id': 'https://openalex.org/C142362112', 'wikidata': 'https://www.wikidata.org/wiki/Q735', 'display_name': 'Art', 'level': 0, 'score': 0.3486744}, {'id': 'https://openalex.org/C161191863', 'wikidata': 'https://www.wikidata.org/wiki/Q199655', 'display_name': 'Library science', 'level': 1, 'score': 0.28478205}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.23853043}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.17610618}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.09547737}], 'mesh': [{'descriptor_ui': 'D000262', 'descriptor_name': 'Adenylyl Cyclases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000262', 'descriptor_name': 'Adenylyl Cyclases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002462', 'descriptor_name': 'Cell Membrane', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002462', 'descriptor_name': 'Cell Membrane', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D003600', 'descriptor_name': 'Cytosol', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003600', 'descriptor_name': 'Cytosol', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D004789', 'descriptor_name': 'Enzyme Activation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005459', 'descriptor_name': 'Fluorides', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D005459', 'descriptor_name': 'Fluorides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005934', 'descriptor_name': 'Glucagon', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005934', 'descriptor_name': 'Glucagon', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D007700', 'descriptor_name': 'Kinetics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011402', 'descriptor_name': 'Pronase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014357', 'descriptor_name': 'Trypsin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/0014-5793(77)80601-7', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/0014-5793%2877%2980601-7', 'source': {'id': 'https://openalex.org/S104830714', 'display_name': 'FEBS Letters', 'issn_l': '0014-5793', 'issn': ['0014-5793', '1873-3468'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/913601', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1016/0014-5793(77)80601-7', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1016/0014-5793%2877%2980601-7', 'source': {'id': 'https://openalex.org/S104830714', 'display_name': 'FEBS Letters', 'issn_l': '0014-5793', 'issn': ['0014-5793', '1873-3468'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 11, 'referenced_works': ['https://openalex.org/W1509728658', 'https://openalex.org/W1518896112', 'https://openalex.org/W1593541101', 'https://openalex.org/W1607167942', 'https://openalex.org/W2022354204', 'https://openalex.org/W2048864315', 'https://openalex.org/W2081363427', 'https://openalex.org/W2141449078', 'https://openalex.org/W2169503005', 'https://openalex.org/W2339890440', 'https://openalex.org/W2418662542'], 'related_works': ['https://openalex.org/W4387497383', 'https://openalex.org/W3103481565', 'https://openalex.org/W2948807893', 'https://openalex.org/W2899084033', 'https://openalex.org/W2778153218', 'https://openalex.org/W2748952813', 'https://openalex.org/W2053922838', 'https://openalex.org/W1983113419', 'https://openalex.org/W180243494', 'https://openalex.org/W1531601525'], 'abstract_inverted_index': {'FEBS': [0, 247], 'LettersVolume': [1], '82,': [2], 'Issue': [3], '2': [4, 214], 'p.': [5], '273-277': [6, 370], 'Full-length': [7], 'articleFree': [8], 'Access': [9], 'Activation': [10], 'of': [11, 30, 33, 52, 55, 77, 80, 99, 102, 143, 153, 166, 177], 'rat': [12], 'liver': [13], 'plasma': [14], 'membrane': [15], 'adenylate': [16], 'cyclase': [17], 'by': [18, 45, 67, 92, 114], 'a': [19, 174], 'cytoplasmic': [20], 'protein': [21], 'factor': [22], 'Christine': [23, 26, 70, 73], 'A.': [24, 27, 71, 74], 'Doberska,': [25, 72], 'Doberska': [28, 75], 'Department': [29, 51, 76, 98], 'Biochemistry,': [31, 53, 78, 100], 'University': [32, 54, 79, 101], 'Cambridge,': [34, 56, 81, 103], 'Tennis': [35, 57, 82, 104], 'Court': [36, 58, 83, 105], 'Road,': [37, 59, 84, 106], 'Cambridge': [38, 60, 85, 107], 'CB2': [39, 61, 86, 108], '1QW,': [40, 62, 87, 109], 'EnglandSearch': [41, 63, 88, 110], 'for': [42, 64, 89, 111], 'more': [43, 65, 90, 112], 'papers': [44, 66, 91, 113], 'this': [46, 68, 93, 115, 178], 'authorB.Richard': [47, 94], 'Martin,': [48, 95, 201, 293], 'B.Richard': [49, 96], 'Martin': [50, 97], 'author': [69, 116], 'First': [117], 'published:': [118], 'October': [119], '15,': [120, 368], '1977': [121], 'https://doi.org/10.1016/0014-5793(77)80601-7Citations:': [122], '20AboutPDF': [123], 'ToolsRequest': [124], 'permissionExport': [125], 'citationAdd': [126], 'to': [127, 149, 172], 'favoritesTrack': [128], 'citation': [129], 'ShareShare': [130], 'Give': [131], 'accessShare': [132, 135], 'full': [133], 'text': [134], 'full-text': [136, 151, 175], 'accessPlease': [137], 'review': [138], 'our': [139], 'Terms': [140, 163], 'and': [141, 145, 157, 164, 183], 'Conditions': [142, 165], 'Use': [144], 'check': [146], 'box': [147], 'below': [148, 171], 'share': [150, 173], 'version': [152, 176], 'article.I': [154], 'have': [155], 'read': [156], 'accept': [158], 'the': [159, 169], 'Wiley': [160], 'Online': [161], 'Library': [162], 'UseShareable': [167], 'LinkUse': [168], 'link': [170], 'article': [179], 'with': [180], 'your': [181], 'friends': [182], 'colleagues.': [184], 'Learn': [185], 'more.Copy': [186], 'URL': [187], 'References': [188], '1': [189], 'M.': [190, 202, 204, 215, 323], 'Rodbell,': [191, 216, 324], 'M.C.': [192], 'Lin,': [193], 'Y.': [194, 319], 'Salomon,': [195, 320], 'C.D.': [196, 321, 334], 'Londos,': [197, 322], 'J.P.': [198], 'Harwood,': [199], 'B.R.': [200, 292], 'Rendell,': [203], 'Berman,': [205], 'Adv.': [206], 'Cyclic': [207], 'Nucleotide': [208], 'Res.,': [209], '5,': [210], '(1975),': [211, 221, 239, 262], '3–': [212], '30.': [213], 'J.': [217, 258, 282, 284, 344], 'Biol.': [218, 259, 285, 345], 'Chem.,': [219, 260, 286, 346], '250,': [220, 261], '5826–': [222], '5834.': [223], '3': [224], 'R-J.': [225], 'Ho,': [226], 'T.R.': [227], 'Russell,': [228], 'T.': [229], 'Osakawa,': [230], 'E.': [231], 'Sutherland,': [232], 'Proc.': [233], 'Natl.': [234], 'Acad.': [235], 'Sci.': [236], 'USA,': [237], '72,': [238], '4739–': [240], '4743.': [241], '4': [242], 'H.': [243], 'Löw,': [244], 'S.': [245], 'Werner,': [246], 'Lett.,': [248], '65,': [249], '(1976),': [250], '96–': [251], '98.': [252], '5': [253], 'D.M.': [254], 'Gill,': [255], 'C.A.': [256], 'King,': [257], '6424–': [263], '6432.': [264], '6': [265], 'R.B.': [266], 'Sanders,': [267], 'W.J.': [268], 'Thompson,': [269], 'G.A.': [270, 354], 'Robinson,': [271], 'Biochim.': [272, 311], 'Biophys.': [273, 312], 'Acta.,': [274], '498,': [275], '(1977),': [276, 288, 299, 361], '10–': [277], '20.': [278], '7': [279], 'F.': [280], 'Pecker,': [281], 'Hanoune,': [283], '252,': [287], '2784–': [289], '2786.': [290], '8': [291], 'H.P.': [294], 'Voorheis,': [295], 'Biochem.': [296, 358], 'J.,': [297, 359], '161,': [298], '555–': [300], '559.': [301], '9': [302], 'S.J.': [303], 'Pilkis,': [304], 'J.H.': [305], 'Exton,': [306], 'R.A.': [307], 'Johnson,': [308], 'C.R.': [309], 'Park,': [310], 'Acta,': [313], '343,': [314], '(1974),': [315, 328], '250–': [316], '267.': [317], '10': [318], 'Anal.': [325], 'Biochem.,': [326], '58,': [327], '541–': [329], '548.': [330], '11': [331], 'D.A.': [332], 'Walsh,': [333], 'Ashby,': [335], 'C.': [336], 'Gonzalez,': [337], 'D.': [338], 'Collins,': [339], 'E.M.': [340], 'Fischer,': [341], 'E.G.': [342], 'Krebs,': [343], '246,': [347], '(1971),': [348], '1977–': [349], '1985.': [350], '12': [351], 'P.': [352], 'Cohen,': [353], 'Nimmo,': [355], 'J.F.': [356], 'Antoniw,': [357], '162,': [360], '435–': [362], '444.': [363], 'Citing': [364], 'Literature': [365], 'Volume82,': [366], 'Issue2October': [367], '1977Pages': [369], 'ReferencesRelatedInformation': [371]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2009925276', 'counts_by_year': [], 'updated_date': '2024-12-09T04:45:33.607058', 'created_date': '2016-06-24'}