Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2008718743', 'doi': 'https://doi.org/10.1126/science.147.3663.1299', 'title': 'Lens Fiber Differentiation and Gamma Crystallins: Immunofluorescent Study of Wolffian Regeneration', 'display_name': 'Lens Fiber Differentiation and Gamma Crystallins: Immunofluorescent Study of Wolffian Regeneration', 'publication_year': 1965, 'publication_date': '1965-03-12', 'ids': {'openalex': 'https://openalex.org/W2008718743', 'doi': 'https://doi.org/10.1126/science.147.3663.1299', 'mag': '2008718743', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/14250323'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1126/science.147.3663.1299', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S3880285', 'display_name': 'Science', 'issn_l': '0036-8075', 'issn': ['0036-8075', '1095-9203'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315823', 'host_organization_name': 'American Association for the Advancement of Science', 'host_organization_lineage': ['https://openalex.org/P4310315823'], 'host_organization_lineage_names': ['American Association for the Advancement of Science'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5091377047', 'display_name': 'Chinami Takata', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1289243028', 'display_name': 'Oak Ridge National Laboratory', 'ror': 'https://ror.org/01qz5mb56', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1289243028', 'https://openalex.org/I1330989302', 'https://openalex.org/I39565521', 'https://openalex.org/I4210159294']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Chinami Takata', 'raw_affiliation_strings': ['Biology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee'], 'affiliations': [{'raw_affiliation_string': 'Biology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee', 'institution_ids': ['https://openalex.org/I1289243028']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5114194203', 'display_name': 'J F Albright', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1289243028', 'display_name': 'Oak Ridge National Laboratory', 'ror': 'https://ror.org/01qz5mb56', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1289243028', 'https://openalex.org/I1330989302', 'https://openalex.org/I39565521', 'https://openalex.org/I4210159294']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'J. F. Albright', 'raw_affiliation_strings': ['Biology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee'], 'affiliations': [{'raw_affiliation_string': 'Biology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee', 'institution_ids': ['https://openalex.org/I1289243028']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5112208500', 'display_name': 'Tuneo Yamada', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1289243028', 'display_name': 'Oak Ridge National Laboratory', 'ror': 'https://ror.org/01qz5mb56', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1289243028', 'https://openalex.org/I1330989302', 'https://openalex.org/I39565521', 'https://openalex.org/I4210159294']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Tuneo Yamada', 'raw_affiliation_strings': ['Biology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee'], 'affiliations': [{'raw_affiliation_string': 'Biology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee', 'institution_ids': ['https://openalex.org/I1289243028']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 6.935, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 62, 'citation_normalized_percentile': {'value': 0.899603, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '147', 'issue': '3663', 'first_page': '1299', 'last_page': '1301'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11480', 'display_name': 'Connexins and lens biology', 'score': 0.8819, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11480', 'display_name': 'Connexins and lens biology', 'score': 0.8819, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/crystallin', 'display_name': 'Crystallin', 'score': 0.5504979}, {'id': 'https://openalex.org/keywords/lens-fiber', 'display_name': 'Lens Fiber', 'score': 0.49282983}], 'concepts': [{'id': 'https://openalex.org/C171056886', 'wikidata': 'https://www.wikidata.org/wiki/Q193119', 'display_name': 'Regeneration (biology)', 'level': 2, 'score': 0.715574}, {'id': 'https://openalex.org/C15336307', 'wikidata': 'https://www.wikidata.org/wiki/Q1766051', 'display_name': 'Lens (geology)', 'level': 2, 'score': 0.64272904}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.60086304}, {'id': 'https://openalex.org/C7263354', 'wikidata': 'https://www.wikidata.org/wiki/Q2992167', 'display_name': 'Crystallin', 'level': 2, 'score': 0.5504979}, {'id': 'https://openalex.org/C2909221355', 'wikidata': 'https://www.wikidata.org/wiki/Q146701', 'display_name': 'Lens Fiber', 'level': 3, 'score': 0.49282983}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.45573223}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.3416992}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.11718702}, {'id': 'https://openalex.org/C2780723820', 'wikidata': 'https://www.wikidata.org/wiki/Q1934178', 'display_name': 'Nucleus', 'level': 2, 'score': 0.050391346}, {'id': 'https://openalex.org/C151730666', 'wikidata': 'https://www.wikidata.org/wiki/Q7205', 'display_name': 'Paleontology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000941', 'descriptor_name': 'Antigens', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D002454', 'descriptor_name': 'Cell Differentiation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D011232', 'descriptor_name': 'Chemical Precipitation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D003459', 'descriptor_name': 'Crystallins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D003956', 'descriptor_name': 'Dialysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D004847', 'descriptor_name': 'Epithelial Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D007106', 'descriptor_name': 'Immune Sera', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D005779', 'descriptor_name': 'Immunodiffusion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D007122', 'descriptor_name': 'Immunoelectrophoresis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D007908', 'descriptor_name': 'Lens, Crystalline', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D007909', 'descriptor_name': 'Lenses', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D012038', 'descriptor_name': 'Regeneration', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D006435', 'descriptor_name': 'Renal Dialysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D012106', 'descriptor_name': 'Research', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D014562', 'descriptor_name': 'Urodela', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D038204', 'descriptor_name': 'beta-Crystallins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D038222', 'descriptor_name': 'gamma-Crystallins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011446', 'descriptor_name': 'Prospective Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1126/science.147.3663.1299', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S3880285', 'display_name': 'Science', 'issn_l': '0036-8075', 'issn': ['0036-8075', '1095-9203'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315823', 'host_organization_name': 'American Association for the Advancement of Science', 'host_organization_lineage': ['https://openalex.org/P4310315823'], 'host_organization_lineage_names': ['American Association for the Advancement of Science'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/14250323', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 18, 'referenced_works': ['https://openalex.org/W1970545092', 'https://openalex.org/W1970682647', 'https://openalex.org/W1982719958', 'https://openalex.org/W1987375491', 'https://openalex.org/W1995276028', 'https://openalex.org/W2018572149', 'https://openalex.org/W2019327345', 'https://openalex.org/W2034459424', 'https://openalex.org/W2043795458', 'https://openalex.org/W2050615946', 'https://openalex.org/W2064205619', 'https://openalex.org/W2066829863', 'https://openalex.org/W2078661760', 'https://openalex.org/W2088787112', 'https://openalex.org/W2088932962', 'https://openalex.org/W2092055247', 'https://openalex.org/W2315085743', 'https://openalex.org/W9313323'], 'related_works': ['https://openalex.org/W4290210633', 'https://openalex.org/W2984843449', 'https://openalex.org/W2794059978', 'https://openalex.org/W2471791057', 'https://openalex.org/W2467393879', 'https://openalex.org/W2297199156', 'https://openalex.org/W2053663019', 'https://openalex.org/W2002299381', 'https://openalex.org/W1989188250', 'https://openalex.org/W1983218064'], 'abstract_inverted_index': {'From': [0], 'the': [1, 26, 56, 60, 76, 82, 85, 90, 96, 101, 103, 124, 131, 135], 'adult': [2, 61], 'lens': [3, 58, 86, 88], 'of': [4, 10, 18, 51, 59, 81, 134], 'Triturus': [5], 'viridescens': [6], ',': [7], 'a': [8, 120, 143], 'fraction': [9, 30], 'proteins': [11], 'was': [12], 'isolated': [13], 'which': [14], 'corresponds': [15], 'to': [16, 100, 109, 141], 'γ-crystallins': [17, 52, 147], 'higher': [19], 'vertebrates.': [20], 'Tests': [21], 'by': [22], 'immunoelectrophoresis': [23], 'indicate': [24, 119], 'that': [25], 'antiserum': [27], 'against': [28], 'this': [29, 41], 'reacts': [31], 'with': [32, 36], 'γ-crystallins,': [33], 'but': [34, 73], 'not': [35, 74], 'α-': [37], 'or': [38], 'β-crystallins.': [39], 'With': [40], 'antiserum,': [42], 'an': [43], 'immunofluorescent': [44], 'reagent': [45], 'has': [46], 'been': [47], 'prepared': [48], 'for': [49], 'detection': [50], 'from': [53], 'newts.': [54], 'In': [55], 'normal': [57], 'newt,': [62], 'these': [63], 'crystallins': [64], 'are': [65, 128], 'detected': [66], 'in': [67, 75, 95, 116], 'fiber': [68, 71, 106, 117, 126, 149], 'cells': [69, 107, 115, 127], 'and': [70], 'material,': [72], 'epithelial': [77], 'cells.': [78], 'During': [79], 'transformation': [80], 'iris': [83], 'into': [84], 'after': [87], 'removal,': [89], 'staining': [91], 'reaction': [92], 'is': [93], 'negative': [94], 'regenerating': [97, 136], 'tissue': [98], 'up': [99], 'time': [102], 'prospective': [104], 'primary': [105], 'begin': [108, 140], 'elongate.': [110], 'Subsequently,': [111], 'without': [112], 'exception': [113], 'those': [114], 'differentiation': [118], 'γ-crystallin': [121, 144], 'reaction.': [122, 145], 'When': [123], 'secondary': [125], 'produced': [129], 'at': [130], 'equatorial': [132], 'zone': [133], 'lens,': [137], 'they': [138], 'also': [139], 'show': [142], 'Thus,': [146], 'characterize': [148], 'differentiation.': [150]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2008718743', 'counts_by_year': [{'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}], 'updated_date': '2024-12-08T07:44:10.264649', 'created_date': '2016-06-24'}