Title: Vitamins and photoaging: Do scientific data support their use?
Abstract: With the rise of the cosmeceutical industry, numerous formulations have surfaced with claims of reducing the clinical manifestations of photoaging. Many of these products capitalize on the positive connection the public makes with vitamins, especially with respect to their antioxidant capabilities. An impressive amount of basic science and clinical research has been conducted in both an attempt to discover novel strategies for preventing detrimental sun damage and to validate the addition of vitamins to skin care products. As dermatologists, it will be essential to provide our patients with substantiated counseling regarding the efficacy of commercial assertions. In this review, we will systematically examine the evidence supporting the use of vitamins in oral and topical formulations and provide a brief summary of the pathogenesis of photoaging. Limitations of this study include that there may be unpublished data or additional studies that may have been overlooked in our comprehensive review of this topic. With the rise of the cosmeceutical industry, numerous formulations have surfaced with claims of reducing the clinical manifestations of photoaging. Many of these products capitalize on the positive connection the public makes with vitamins, especially with respect to their antioxidant capabilities. An impressive amount of basic science and clinical research has been conducted in both an attempt to discover novel strategies for preventing detrimental sun damage and to validate the addition of vitamins to skin care products. As dermatologists, it will be essential to provide our patients with substantiated counseling regarding the efficacy of commercial assertions. In this review, we will systematically examine the evidence supporting the use of vitamins in oral and topical formulations and provide a brief summary of the pathogenesis of photoaging. Limitations of this study include that there may be unpublished data or additional studies that may have been overlooked in our comprehensive review of this topic. β-Carotene and cardiovascular riskJournal of the American Academy of DermatologyVol. 64Issue 4PreviewTo the Editor: I read with interest the article "Vitamins and photoaging: Do scientific data support their use?" by Zussmann, Ahdout, and Kim.1 The authors report the increase of the minimal erythema dose (MED) after systemic long-term application of ß-carotene in some studies2 and suggest the importance of larger scale clinical trials to investigate the photoprotective effect of ß-carotene.1 Full-Text PDF
Publication Year: 2010
Publication Date: 2010-03-02
Language: en
Type: review
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 66
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot