Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2007455368', 'doi': 'https://doi.org/10.1021/ac4000514', 'title': 'Single Nanoparticle Detection for Multiplexed Protein Diagnostics with Attomolar Sensitivity in Serum and Unprocessed Whole Blood', 'display_name': 'Single Nanoparticle Detection for Multiplexed Protein Diagnostics with Attomolar Sensitivity in Serum and Unprocessed Whole Blood', 'publication_year': 2013, 'publication_date': '2013-03-08', 'ids': {'openalex': 'https://openalex.org/W2007455368', 'doi': 'https://doi.org/10.1021/ac4000514', 'mag': '2007455368', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/23469929', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3690328'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/ac4000514', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S191963794', 'display_name': 'Analytical Chemistry', 'issn_l': '0003-2700', 'issn': ['0003-2700', '1520-6882'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://europepmc.org/articles/pmc3690328?pdf=render', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5037599525', 'display_name': 'Margo R. Monroe', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I111088046', 'display_name': 'Boston University', 'ror': 'https://ror.org/05qwgg493', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111088046']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Margo R. Monroe', 'raw_affiliation_strings': ['Department of Biomedical#R#Engineering, Boston University, 44 Cummington Street, Boston, Massachusetts 02215, United States'], 'affiliations': [{'raw_affiliation_string': 'Department of Biomedical#R#Engineering, Boston University, 44 Cummington Street, Boston, Massachusetts 02215, United States', 'institution_ids': ['https://openalex.org/I111088046']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5011971881', 'display_name': 'George G. Daaboul', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I111088046', 'display_name': 'Boston University', 'ror': 'https://ror.org/05qwgg493', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111088046']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'George G. Daaboul', 'raw_affiliation_strings': ['Department of Biomedical#R#Engineering, Boston University, 44 Cummington Street, Boston, Massachusetts 02215, United States'], 'affiliations': [{'raw_affiliation_string': 'Department of Biomedical#R#Engineering, Boston University, 44 Cummington Street, Boston, Massachusetts 02215, United States', 'institution_ids': ['https://openalex.org/I111088046']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5072911123', 'display_name': 'Ahmet Tüysüzoğlu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I111088046', 'display_name': 'Boston University', 'ror': 'https://ror.org/05qwgg493', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111088046']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ahmet Tuysuzoglu', 'raw_affiliation_strings': ['Department of Electrical\rand Computer Engineering, Boston University, 8 St. Mary’s Street, Boston, Massachussetts 02215, United\rStates'], 'affiliations': [{'raw_affiliation_string': 'Department of Electrical\rand Computer Engineering, Boston University, 8 St. Mary’s Street, Boston, Massachussetts 02215, United\rStates', 'institution_ids': ['https://openalex.org/I111088046']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042950398', 'display_name': 'Carlos López', 'orcid': 'https://orcid.org/0000-0002-8901-741X'}, 'institutions': [{'id': 'https://openalex.org/I111088046', 'display_name': 'Boston University', 'ror': 'https://ror.org/05qwgg493', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111088046']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Carlos A. Lopez', 'raw_affiliation_strings': ['Department of Electrical\rand Computer Engineering, Boston University, 8 St. Mary’s Street, Boston, Massachussetts 02215, United\rStates'], 'affiliations': [{'raw_affiliation_string': 'Department of Electrical\rand Computer Engineering, Boston University, 8 St. Mary’s Street, Boston, Massachussetts 02215, United\rStates', 'institution_ids': ['https://openalex.org/I111088046']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5041920750', 'display_name': 'Frédéric F. Little', 'orcid': 'https://orcid.org/0000-0003-4342-7007'}, 'institutions': [{'id': 'https://openalex.org/I111088046', 'display_name': 'Boston University', 'ror': 'https://ror.org/05qwgg493', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111088046']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Frédéric F. Little', 'raw_affiliation_strings': ['Pulmonary Center, Boston University School of Medicine, 715 Albany Street, Boston, Massachusetts 02118, United States'], 'affiliations': [{'raw_affiliation_string': 'Pulmonary Center, Boston University School of Medicine, 715 Albany Street, Boston, Massachusetts 02118, United States', 'institution_ids': ['https://openalex.org/I111088046']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5036201173', 'display_name': 'M. Selim Ünlü', 'orcid': 'https://orcid.org/0000-0002-8594-892X'}, 'institutions': [{'id': 'https://openalex.org/I111088046', 'display_name': 'Boston University', 'ror': 'https://ror.org/05qwgg493', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I111088046']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'M. Selim Ünlü', 'raw_affiliation_strings': ['Department of Biomedical\rEngineering, Boston University, 44 Cummington Street, Boston, Massachusetts 02215, United States', 'Department of Electrical\rand Computer Engineering, Boston University, 8 St. Mary’s Street, Boston, Massachussetts 02215, United\rStates', 'Physics Department, Boston University, 590 Commonwealth\rAvenue, Boston, Massachusetts 02215, United States'], 'affiliations': [{'raw_affiliation_string': 'Department of Biomedical\rEngineering, Boston University, 44 Cummington Street, Boston, Massachusetts 02215, United States', 'institution_ids': ['https://openalex.org/I111088046']}, {'raw_affiliation_string': 'Department of Electrical\rand Computer Engineering, Boston University, 8 St. Mary’s Street, Boston, Massachussetts 02215, United\rStates', 'institution_ids': ['https://openalex.org/I111088046']}, {'raw_affiliation_string': 'Physics Department, Boston University, 590 Commonwealth\rAvenue, Boston, Massachusetts 02215, United States', 'institution_ids': ['https://openalex.org/I111088046']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 5.207, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 73, 'citation_normalized_percentile': {'value': 0.999975, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '85', 'issue': '7', 'first_page': '3698', 'last_page': '3706'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11393', 'display_name': 'Biosensors and Analytical Detection', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2204', 'display_name': 'Biomedical Engineering'}, 'field': {'id': 'https://openalex.org/fields/22', 'display_name': 'Engineering'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11393', 'display_name': 'Biosensors and Analytical Detection', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2204', 'display_name': 'Biomedical Engineering'}, 'field': {'id': 'https://openalex.org/fields/22', 'display_name': 'Engineering'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T12867', 'display_name': 'Advanced Biosensing Techniques and Applications', 'score': 0.9993, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10207', 'display_name': 'Advanced biosensing and bioanalysis techniques', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/bioanalysis', 'display_name': 'Bioanalysis', 'score': 0.45764488}, {'id': 'https://openalex.org/keywords/assay-sensitivity', 'display_name': 'Assay sensitivity', 'score': 0.4236634}], 'concepts': [{'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.7443494}, {'id': 'https://openalex.org/C104819515', 'wikidata': 'https://www.wikidata.org/wiki/Q900961', 'display_name': 'Colloidal gold', 'level': 3, 'score': 0.62090224}, {'id': 'https://openalex.org/C1621761', 'wikidata': 'https://www.wikidata.org/wiki/Q7997549', 'display_name': 'Whole blood', 'level': 2, 'score': 0.47488827}, {'id': 'https://openalex.org/C155672457', 'wikidata': 'https://www.wikidata.org/wiki/Q61231', 'display_name': 'Nanoparticle', 'level': 2, 'score': 0.4748633}, {'id': 'https://openalex.org/C160756335', 'wikidata': 'https://www.wikidata.org/wiki/Q669391', 'display_name': 'Biosensor', 'level': 2, 'score': 0.46574602}, {'id': 'https://openalex.org/C137535248', 'wikidata': 'https://www.wikidata.org/wiki/Q4914691', 'display_name': 'Bioanalysis', 'level': 2, 'score': 0.45764488}, {'id': 'https://openalex.org/C19275194', 'wikidata': 'https://www.wikidata.org/wiki/Q222903', 'display_name': 'Multiplexing', 'level': 2, 'score': 0.45089296}, {'id': 'https://openalex.org/C87133666', 'wikidata': 'https://www.wikidata.org/wiki/Q1161699', 'display_name': 'Dynamic range', 'level': 2, 'score': 0.45020288}, {'id': 'https://openalex.org/C2780367336', 'wikidata': 'https://www.wikidata.org/wiki/Q4808618', 'display_name': 'Assay sensitivity', 'level': 3, 'score': 0.4236634}, {'id': 'https://openalex.org/C43617362', 'wikidata': 'https://www.wikidata.org/wiki/Q170050', 'display_name': 'Chromatography', 'level': 1, 'score': 0.42231363}, {'id': 'https://openalex.org/C171250308', 'wikidata': 'https://www.wikidata.org/wiki/Q11468', 'display_name': 'Nanotechnology', 'level': 1, 'score': 0.37465978}, {'id': 'https://openalex.org/C192562407', 'wikidata': 'https://www.wikidata.org/wiki/Q228736', 'display_name': 'Materials science', 'level': 0, 'score': 0.115721285}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.10368815}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.09842512}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.095016986}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C76155785', 'wikidata': 'https://www.wikidata.org/wiki/Q418', 'display_name': 'Telecommunications', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C204787440', 'wikidata': 'https://www.wikidata.org/wiki/Q188504', 'display_name': 'Alternative medicine', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C31972630', 'wikidata': 'https://www.wikidata.org/wiki/Q844240', 'display_name': 'Computer vision', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D015374', 'descriptor_name': 'Biosensing Techniques', 'qualifier_ui': 'Q000295', 'qualifier_name': 'instrumentation', 'is_major_topic': True}, {'descriptor_ui': 'D007073', 'descriptor_name': 'Immunoglobulin E', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': True}, {'descriptor_ui': 'D007368', 'descriptor_name': 'Interferometry', 'qualifier_ui': 'Q000295', 'qualifier_name': 'instrumentation', 'is_major_topic': True}, {'descriptor_ui': 'D007782', 'descriptor_name': 'Lactoglobulins', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D008892', 'descriptor_name': 'Milk', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D008894', 'descriptor_name': 'Milk Proteins', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': True}, {'descriptor_ui': 'D053758', 'descriptor_name': 'Nanoparticles', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002417', 'descriptor_name': 'Cattle', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006046', 'descriptor_name': 'Gold', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012680', 'descriptor_name': 'Sensitivity and Specificity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000067816', 'descriptor_name': 'Whey Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/ac4000514', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S191963794', 'display_name': 'Analytical Chemistry', 'issn_l': '0003-2700', 'issn': ['0003-2700', '1520-6882'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3690328', 'pdf_url': 'https://europepmc.org/articles/pmc3690328?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690328', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/23469929', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3690328', 'pdf_url': 'https://europepmc.org/articles/pmc3690328?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, 'sustainable_development_goals': [{'display_name': 'Reduced inequalities', 'id': 'https://metadata.un.org/sdg/10', 'score': 0.56}, {'display_name': 'Peace, justice, and strong institutions', 'id': 'https://metadata.un.org/sdg/16', 'score': 0.44}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 44, 'referenced_works': ['https://openalex.org/W1523408885', 'https://openalex.org/W1554342785', 'https://openalex.org/W1965128640', 'https://openalex.org/W1966528088', 'https://openalex.org/W1986190378', 'https://openalex.org/W1992825075', 'https://openalex.org/W2002311984', 'https://openalex.org/W2006175681', 'https://openalex.org/W2017199648', 'https://openalex.org/W2023834245', 'https://openalex.org/W2025383700', 'https://openalex.org/W2034630077', 'https://openalex.org/W2040248861', 'https://openalex.org/W2042024782', 'https://openalex.org/W2042242299', 'https://openalex.org/W2047487070', 'https://openalex.org/W2047583003', 'https://openalex.org/W2050169635', 'https://openalex.org/W2053173757', 'https://openalex.org/W2054142953', 'https://openalex.org/W2056852151', 'https://openalex.org/W2059990887', 'https://openalex.org/W2076958395', 'https://openalex.org/W2077002902', 'https://openalex.org/W2078152402', 'https://openalex.org/W2079307174', 'https://openalex.org/W2082454728', 'https://openalex.org/W2092198587', 'https://openalex.org/W2092506361', 'https://openalex.org/W2104310353', 'https://openalex.org/W2112496633', 'https://openalex.org/W2124476656', 'https://openalex.org/W2125488056', 'https://openalex.org/W2126841531', 'https://openalex.org/W2144541036', 'https://openalex.org/W2157772478', 'https://openalex.org/W2160312052', 'https://openalex.org/W2165856637', 'https://openalex.org/W2170895924', 'https://openalex.org/W2171099211', 'https://openalex.org/W2330350271', 'https://openalex.org/W2482651071', 'https://openalex.org/W4245892117', 'https://openalex.org/W4248902135'], 'related_works': ['https://openalex.org/W4386177067', 'https://openalex.org/W4236642568', 'https://openalex.org/W2922172189', 'https://openalex.org/W2582170511', 'https://openalex.org/W2332256378', 'https://openalex.org/W2029834747', 'https://openalex.org/W1989527423', 'https://openalex.org/W1901350058', 'https://openalex.org/W1559711715', 'https://openalex.org/W1547428108'], 'abstract_inverted_index': {'Although': [0], 'biomarkers': [1, 56], 'exist': [2], 'for': [3, 31, 249], 'a': [4, 9, 17, 32, 65, 83, 94, 162, 199], 'range': [5, 165], 'of': [6, 34, 92, 104, 111, 119, 129, 154, 159], 'disease': [7], 'diagnostics,': [8], 'single': [10, 50], 'low-cost': [11], 'platform': [12], 'exhibiting': [13], 'the': [14, 152, 236], 'required': [15], 'sensitivity,': [16], 'large': [18, 163, 203], 'dynamic-range': [19], 'and': [20, 23, 48, 60, 70, 106, 133, 201, 230, 240, 251], 'multiplexing': [21], 'capability,': [22], 'zero': [24], 'sample': [25], 'preparation': [26], 'remains': [27], 'in': [28, 57, 100, 189], 'high': [29], 'demand': [30], 'variety': [33], 'clinical': [35, 117, 250], 'applications.': [36, 253], 'The': [37, 116], 'Interferometric': [38], 'Reflectance': [39], 'Imaging': [40], 'Sensor': [41], '(IRIS)': [42], 'was': [43, 75, 121], 'utilized': [44], 'to': [45, 53, 78, 177, 186, 225], 'digitally': [46], 'detect': [47], 'size': [49], 'gold': [51, 149], 'nanoparticles': [52, 196], 'identify': [54], 'protein': [55, 98, 208], 'unprocessed': [58, 134, 190], 'serum': [59, 101, 132], 'blood': [61, 108, 136], 'samples.': [62], 'IRIS': [63, 120, 171, 245], 'is': [64], 'simple,': [66], 'inexpensive,': [67, 238], 'multiplexed,': [68], 'high-throughput,': [69], 'label-free': [71], 'optical': [72], 'biosensor': [73], 'that': [74, 234], 'originally': [76], 'used': [77], 'quantify': [79], 'biomass': [80], 'captured': [81], 'on': [82, 198], 'surface': [84], 'with': [85, 146, 210], 'moderate': [86], 'sensitivity.': [87, 115], 'Here': [88], 'we': [89], 'demonstrate': [90], 'detection': [91], 'β-lactoglobulin,': [93], "cow's": [95], 'milk': [96], 'whey': [97], 'spiked': [99], '(>10': [102], 'orders': [103, 110], 'magnitude)': [105], 'whole': [107, 135], '(>5': [109], 'magnitude),': [112], 'at': [113], 'attomolar': [114, 185], 'utility': [118], 'demonstrated': [122], 'by': [123, 138], 'detecting': [124], 'allergen-specific': [125], 'IgE': [126, 144], 'from': [127, 184], 'microliters': [128], 'characterized': [130], 'human': [131, 143], 'samples': [137], 'using': [139], 'secondary': [140], 'antibodies': [141], 'against': [142], 'labeled': [145], '40': [147], 'nm': [148, 217], 'nanoparticles.': [150], 'To': [151], 'best': [153], 'our': [155], 'knowledge,': [156], 'this': [157], 'level': [158], 'sensitivity': [160], 'over': [161], 'dynamic': [164], 'has': [166], 'not': [167], 'been': [168], 'previously': [169], 'demonstrated.': [170], 'offers': [172], 'four': [173], 'main': [174], 'advantages': [175], 'compared': [176, 224], 'existing': [178], 'technologies:': [179], 'it': [180], '(i)': [181], 'detects': [182, 207], 'proteins': [183], 'nanomolar': [187], 'concentrations': [188], 'biological': [191], 'samples,': [192], '(ii)': [193], 'unambiguously': [194], 'discriminates': [195], 'tags': [197, 215], 'robust': [200], 'physically': [202], 'sensor': [204], 'area,': [205], '(iii)': [206], 'targets': [209], 'conjugated': [211], 'very': [212], 'small': [213], 'nanoparticle': [214], '(~40': [216], 'diameter),': [218], 'which': [219], 'minimally': [220], 'affect': [221], 'assay': [222], 'kinetics': [223], 'conventional': [226], 'microparticle': [227], 'tagging': [228], 'methods,': [229], '(iv)': [231], 'utilizes': [232], 'components': [233], 'make': [235, 244], 'instrument': [237], 'robust,': [239], 'portable.': [241], 'These': [242], 'features': [243], 'an': [246], 'ideal': [247], 'candidate': [248], 'diagnostic': [252]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2007455368', 'counts_by_year': [{'year': 2024, 'cited_by_count': 6}, {'year': 2023, 'cited_by_count': 7}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 9}, {'year': 2015, 'cited_by_count': 10}, {'year': 2014, 'cited_by_count': 8}, {'year': 2013, 'cited_by_count': 2}], 'updated_date': '2024-12-12T10:34:49.694948', 'created_date': '2016-06-24'}