Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2007143460', 'doi': 'https://doi.org/10.1083/jcb.121.6.1221', 'title': 'GLUT-4 NH2 terminus contains a phenylalanine-based targeting motif that regulates intracellular sequestration.', 'display_name': 'GLUT-4 NH2 terminus contains a phenylalanine-based targeting motif that regulates intracellular sequestration.', 'publication_year': 1993, 'publication_date': '1993-06-15', 'ids': {'openalex': 'https://openalex.org/W2007143460', 'doi': 'https://doi.org/10.1083/jcb.121.6.1221', 'mag': '2007143460', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/8509445', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2119717'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1083/jcb.121.6.1221', 'pdf_url': 'https://rupress.org/jcb/article-pdf/121/6/1221/1257352/1221.pdf', 'source': {'id': 'https://openalex.org/S96410829', 'display_name': 'The Journal of Cell Biology', 'issn_l': '0021-9525', 'issn': ['0021-9525', '1540-8140'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://rupress.org/jcb/article-pdf/121/6/1221/1257352/1221.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5004382546', 'display_name': 'Robert C. Piper', 'orcid': 'https://orcid.org/0000-0001-9995-5699'}, 'institutions': [{'id': 'https://openalex.org/I204465549', 'display_name': 'Washington University in St. Louis', 'ror': 'https://ror.org/01yc7t268', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I204465549']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'R C Piper', 'raw_affiliation_strings': ['Department of Cell Biology and Physiology, Washington University, St. Louis, MO 63110.'], 'affiliations': [{'raw_affiliation_string': 'Department of Cell Biology and Physiology, Washington University, St. Louis, MO 63110.', 'institution_ids': ['https://openalex.org/I204465549']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5056160223', 'display_name': 'Cheng‐Chi Tai', 'orcid': 'https://orcid.org/0000-0001-9197-4721'}, 'institutions': [{'id': 'https://openalex.org/I204465549', 'display_name': 'Washington University in St. Louis', 'ror': 'https://ror.org/01yc7t268', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I204465549']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'C Tai', 'raw_affiliation_strings': ['Department of Cell Biology and Physiology, Washington University, St. Louis, MO 63110.'], 'affiliations': [{'raw_affiliation_string': 'Department of Cell Biology and Physiology, Washington University, St. Louis, MO 63110.', 'institution_ids': ['https://openalex.org/I204465549']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5029458576', 'display_name': 'Peter Kulesza', 'orcid': 'https://orcid.org/0000-0002-5103-1785'}, 'institutions': [{'id': 'https://openalex.org/I204465549', 'display_name': 'Washington University in St. Louis', 'ror': 'https://ror.org/01yc7t268', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I204465549']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'P Kulesza', 'raw_affiliation_strings': ['Department of Cell Biology and Physiology, Washington University, St. Louis, MO 63110.'], 'affiliations': [{'raw_affiliation_string': 'Department of Cell Biology and Physiology, Washington University, St. Louis, MO 63110.', 'institution_ids': ['https://openalex.org/I204465549']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5043514821', 'display_name': 'S.F. Pang', 'orcid': 'https://orcid.org/0000-0002-7872-1524'}, 'institutions': [{'id': 'https://openalex.org/I204465549', 'display_name': 'Washington University in St. Louis', 'ror': 'https://ror.org/01yc7t268', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I204465549']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'S Pang', 'raw_affiliation_strings': ['Department of Cell Biology and Physiology, Washington University, St. Louis, MO 63110.'], 'affiliations': [{'raw_affiliation_string': 'Department of Cell Biology and Physiology, Washington University, St. Louis, MO 63110.', 'institution_ids': ['https://openalex.org/I204465549']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035259090', 'display_name': 'Dale E. Warnock', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I204465549', 'display_name': 'Washington University in St. Louis', 'ror': 'https://ror.org/01yc7t268', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I204465549']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'D Warnock', 'raw_affiliation_strings': ['Department of Cell Biology and Physiology, Washington University, St. Louis, MO 63110.'], 'affiliations': [{'raw_affiliation_string': 'Department of Cell Biology and Physiology, Washington University, St. Louis, MO 63110.', 'institution_ids': ['https://openalex.org/I204465549']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5036903689', 'display_name': 'John E. Baenziger', 'orcid': 'https://orcid.org/0000-0002-2888-5328'}, 'institutions': [{'id': 'https://openalex.org/I204465549', 'display_name': 'Washington University in St. Louis', 'ror': 'https://ror.org/01yc7t268', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I204465549']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'J Baenziger', 'raw_affiliation_strings': ['Department of Cell Biology and Physiology, Washington University, St. Louis, MO 63110.'], 'affiliations': [{'raw_affiliation_string': 'Department of Cell Biology and Physiology, Washington University, St. Louis, MO 63110.', 'institution_ids': ['https://openalex.org/I204465549']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5012799071', 'display_name': 'J W Slot', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I204465549', 'display_name': 'Washington University in St. Louis', 'ror': 'https://ror.org/01yc7t268', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I204465549']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'J W Slot', 'raw_affiliation_strings': ['Department of Cell Biology and Physiology, Washington University, St. Louis, MO 63110.'], 'affiliations': [{'raw_affiliation_string': 'Department of Cell Biology and Physiology, Washington University, St. Louis, MO 63110.', 'institution_ids': ['https://openalex.org/I204465549']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5080897795', 'display_name': 'Hans J. Geuze', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I204465549', 'display_name': 'Washington University in St. Louis', 'ror': 'https://ror.org/01yc7t268', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I204465549']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'H J Geuze', 'raw_affiliation_strings': ['Department of Cell Biology and Physiology, Washington University, St. Louis, MO 63110.'], 'affiliations': [{'raw_affiliation_string': 'Department of Cell Biology and Physiology, Washington University, St. Louis, MO 63110.', 'institution_ids': ['https://openalex.org/I204465549']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5070945300', 'display_name': 'Claudia Puri', 'orcid': 'https://orcid.org/0000-0001-7080-9938'}, 'institutions': [{'id': 'https://openalex.org/I204465549', 'display_name': 'Washington University in St. Louis', 'ror': 'https://ror.org/01yc7t268', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I204465549']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'C Puri', 'raw_affiliation_strings': ['Department of Cell Biology and Physiology, Washington University, St. Louis, MO 63110.'], 'affiliations': [{'raw_affiliation_string': 'Department of Cell Biology and Physiology, Washington University, St. Louis, MO 63110.', 'institution_ids': ['https://openalex.org/I204465549']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5014643889', 'display_name': 'David E. James', 'orcid': 'https://orcid.org/0000-0001-5946-5257'}, 'institutions': [{'id': 'https://openalex.org/I204465549', 'display_name': 'Washington University in St. Louis', 'ror': 'https://ror.org/01yc7t268', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I204465549']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'D E James', 'raw_affiliation_strings': ['Department of Cell Biology and Physiology, Washington University, St. Louis, MO 63110.'], 'affiliations': [{'raw_affiliation_string': 'Department of Cell Biology and Physiology, Washington University, St. Louis, MO 63110.', 'institution_ids': ['https://openalex.org/I204465549']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 5.605, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 118, 'citation_normalized_percentile': {'value': 0.904177, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '121', 'issue': '6', 'first_page': '1221', 'last_page': '1232'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11339', 'display_name': 'Role of AMP-Activated Protein Kinase in Cellular Metabolism', 'score': 0.9933, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11339', 'display_name': 'Role of AMP-Activated Protein Kinase in Cellular Metabolism', 'score': 0.9933, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10613', 'display_name': 'Gene Therapy Techniques and Applications', 'score': 0.9858, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12827', 'display_name': 'Nucleotide Metabolism and Enzyme Regulation', 'score': 0.9852, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/c-terminus', 'display_name': 'C-terminus', 'score': 0.7512306}, {'id': 'https://openalex.org/keywords/alanine', 'display_name': 'Alanine', 'score': 0.6287171}, {'id': 'https://openalex.org/keywords/glycogen-metabolism', 'display_name': 'Glycogen Metabolism', 'score': 0.46462}, {'id': 'https://openalex.org/keywords/amino-acid-transporter', 'display_name': 'Amino acid transporter', 'score': 0.4469395}], 'concepts': [{'id': 'https://openalex.org/C57711820', 'wikidata': 'https://www.wikidata.org/wiki/Q310425', 'display_name': 'C-terminus', 'level': 3, 'score': 0.7512306}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.72502947}, {'id': 'https://openalex.org/C2779856020', 'wikidata': 'https://www.wikidata.org/wiki/Q218642', 'display_name': 'Alanine', 'level': 3, 'score': 0.6287171}, {'id': 'https://openalex.org/C515207424', 'wikidata': 'https://www.wikidata.org/wiki/Q8066', 'display_name': 'Amino acid', 'level': 2, 'score': 0.6051434}, {'id': 'https://openalex.org/C161573976', 'wikidata': 'https://www.wikidata.org/wiki/Q420277', 'display_name': 'Glucose transporter', 'level': 3, 'score': 0.58897895}, {'id': 'https://openalex.org/C14053116', 'wikidata': 'https://www.wikidata.org/wiki/Q284398', 'display_name': 'N-terminus', 'level': 4, 'score': 0.58712816}, {'id': 'https://openalex.org/C79879829', 'wikidata': 'https://www.wikidata.org/wiki/Q5571762', 'display_name': 'Intracellular', 'level': 2, 'score': 0.5731664}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.50421035}, {'id': 'https://openalex.org/C118892022', 'wikidata': 'https://www.wikidata.org/wiki/Q7834587', 'display_name': 'Transmembrane domain', 'level': 3, 'score': 0.47874683}, {'id': 'https://openalex.org/C120405084', 'wikidata': 'https://www.wikidata.org/wiki/Q285307', 'display_name': 'Symporter', 'level': 4, 'score': 0.45475614}, {'id': 'https://openalex.org/C190062978', 'wikidata': 'https://www.wikidata.org/wiki/Q79899', 'display_name': 'Cytoplasm', 'level': 2, 'score': 0.45138365}, {'id': 'https://openalex.org/C2781313199', 'wikidata': 'https://www.wikidata.org/wiki/Q4746435', 'display_name': 'Amino acid transporter', 'level': 4, 'score': 0.4469395}, {'id': 'https://openalex.org/C53345823', 'wikidata': 'https://www.wikidata.org/wiki/Q5531554', 'display_name': 'Gene isoform', 'level': 3, 'score': 0.44514155}, {'id': 'https://openalex.org/C175656101', 'wikidata': 'https://www.wikidata.org/wiki/Q56646', 'display_name': 'Chinese hamster ovary cell', 'level': 3, 'score': 0.41265982}, {'id': 'https://openalex.org/C149011108', 'wikidata': 'https://www.wikidata.org/wiki/Q652985', 'display_name': 'Transporter', 'level': 3, 'score': 0.39140776}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.38622075}, {'id': 'https://openalex.org/C167625842', 'wikidata': 'https://www.wikidata.org/wiki/Q899763', 'display_name': 'Peptide sequence', 'level': 3, 'score': 0.3607338}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.35381687}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.23300004}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.21908712}, {'id': 'https://openalex.org/C2779306644', 'wikidata': 'https://www.wikidata.org/wiki/Q2002370', 'display_name': 'Insulin', 'level': 2, 'score': 0.11681712}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D009004', 'descriptor_name': 'Monosaccharide Transport Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D009004', 'descriptor_name': 'Monosaccharide Transport Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D009124', 'descriptor_name': 'Muscle Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000595', 'descriptor_name': 'Amino Acid Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001692', 'descriptor_name': 'Biological Transport', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016466', 'descriptor_name': 'CHO Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002966', 'descriptor_name': 'Clathrin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006224', 'descriptor_name': 'Cricetinae', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003847', 'descriptor_name': 'Deoxyglucose', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D003847', 'descriptor_name': 'Deoxyglucose', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051275', 'descriptor_name': 'Glucose Transporter Type 4', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009004', 'descriptor_name': 'Monosaccharide Transport Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010649', 'descriptor_name': 'Phenylalanine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D021382', 'descriptor_name': 'Protein Sorting Signals', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D021382', 'descriptor_name': 'Protein Sorting Signals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017384', 'descriptor_name': 'Sequence Deletion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013329', 'descriptor_name': 'Structure-Activity Relationship', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013347', 'descriptor_name': 'Subcellular Fractions', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013347', 'descriptor_name': 'Subcellular Fractions', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1083/jcb.121.6.1221', 'pdf_url': 'https://rupress.org/jcb/article-pdf/121/6/1221/1257352/1221.pdf', 'source': {'id': 'https://openalex.org/S96410829', 'display_name': 'The Journal of Cell Biology', 'issn_l': '0021-9525', 'issn': ['0021-9525', '1540-8140'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2119717', 'pdf_url': 'https://europepmc.org/articles/pmc2119717?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2119717', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/8509445', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1083/jcb.121.6.1221', 'pdf_url': 'https://rupress.org/jcb/article-pdf/121/6/1221/1257352/1221.pdf', 'source': {'id': 'https://openalex.org/S96410829', 'display_name': 'The Journal of Cell Biology', 'issn_l': '0021-9525', 'issn': ['0021-9525', '1540-8140'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 45, 'referenced_works': ['https://openalex.org/W120166209', 'https://openalex.org/W1483819615', 'https://openalex.org/W1490846487', 'https://openalex.org/W1493638086', 'https://openalex.org/W1519083075', 'https://openalex.org/W1526233070', 'https://openalex.org/W1529141138', 'https://openalex.org/W1556712517', 'https://openalex.org/W1564186686', 'https://openalex.org/W1583703772', 'https://openalex.org/W1645373081', 'https://openalex.org/W1874037893', 'https://openalex.org/W1911305856', 'https://openalex.org/W1972580189', 'https://openalex.org/W1976177239', 'https://openalex.org/W1977834451', 'https://openalex.org/W1989424897', 'https://openalex.org/W1991410135', 'https://openalex.org/W1995696385', 'https://openalex.org/W1997862023', 'https://openalex.org/W2001736800', 'https://openalex.org/W2018364757', 'https://openalex.org/W2044343226', 'https://openalex.org/W2059031237', 'https://openalex.org/W2061462231', 'https://openalex.org/W2065009864', 'https://openalex.org/W2067691363', 'https://openalex.org/W2070892520', 'https://openalex.org/W2074045232', 'https://openalex.org/W2074783201', 'https://openalex.org/W2080066315', 'https://openalex.org/W2080828698', 'https://openalex.org/W2082861222', 'https://openalex.org/W2109223015', 'https://openalex.org/W2115569175', 'https://openalex.org/W2126564161', 'https://openalex.org/W2128840474', 'https://openalex.org/W2138270253', 'https://openalex.org/W2150207458', 'https://openalex.org/W2156126895', 'https://openalex.org/W2328895879', 'https://openalex.org/W2408312165', 'https://openalex.org/W48961390', 'https://openalex.org/W69372474', 'https://openalex.org/W70275427'], 'related_works': ['https://openalex.org/W4239447438', 'https://openalex.org/W3022297939', 'https://openalex.org/W2582504713', 'https://openalex.org/W2132963149', 'https://openalex.org/W2090709720', 'https://openalex.org/W2086473487', 'https://openalex.org/W2078660393', 'https://openalex.org/W2063199722', 'https://openalex.org/W1994858472', 'https://openalex.org/W1991233227'], 'abstract_inverted_index': {'Expression': [0], 'of': [1, 4, 6, 25, 35, 70, 103, 127, 147, 202, 215, 219, 260, 278], 'chimeras,': [2], 'composed': [3], 'portions': [5], 'two': [7], 'different': [8], 'glucose': [9, 204], 'transporter': [10, 129, 205, 280], 'isoforms': [11], '(GLUT-1': [12], 'and': [13, 166, 239], 'GLUT-4),': [14], 'in': [15, 93, 120, 123, 273], 'CHO': [16, 94], 'cells': [17, 95], 'had': [18], 'indicated': [19], 'that': [20, 31, 256, 267], 'the': [21, 63, 66, 71, 88, 108, 128, 131, 152, 156, 173, 190, 194, 203, 212, 216, 220, 225, 244, 249, 257, 279, 286], 'cytoplasmic': [22, 213], 'NH2': [23, 89, 110, 227, 258], 'terminus': [24, 90, 111, 228, 259], 'GLUT-4': [26, 72, 79, 109, 121, 148, 159, 195, 226, 238, 261], 'contains': [27, 262], 'important': [28], 'targeting': [29, 74, 191, 197, 265], 'information': [30, 192], 'mediates': [32, 268], 'intracellular': [33, 234, 269], 'sequestration': [34, 270], 'this': [36, 167, 207], 'isoform': [37], '(Piper,': [38], 'R.': [39], 'C.,': [40], 'C.': [41, 46, 49], 'Tai,': [42], 'J.': [43, 58], 'W.': [44], 'Slot,': [45], 'S.': [47], 'Hahn,': [48], 'M.': [50], 'Rice,': [51], 'H.': [52], 'Huang,': [53], 'D.': [54], 'E.': [55], 'James.': [56], '1992.': [57], 'Cell': [59], 'Biol.': [60], '117:729-743).': [61], 'In': [62], 'present': [64], 'studies,': [65], 'amino': [67, 105, 137, 176], 'acid': [68], 'constituents': [69], 'NH2-terminal': [73, 82, 196], 'domain': [75, 198, 208], 'have': [76], 'been': [77], 'identified.': [78], 'constructs': [80], 'containing': [81], 'deletions': [83], 'or': [84, 112, 180], 'alanine': [85, 114], 'substitutions': [86], 'within': [87, 193], 'were': [91, 178], 'expressed': [92], 'using': [96], 'a': [97, 124, 263], 'Sindbis': [98], 'virus': [99], 'expression': [100, 146], 'system.': [101], 'Deletion': [102], 'eight': [104], 'acids': [106, 138, 177], 'from': [107, 243], 'substituting': [113], 'for': [115], 'phenylalanine': [116], 'at': [117, 130, 135, 271, 285], 'position': [118], '5': [119], 'resulted': [122], 'marked': [125], 'accumulation': [126], 'plasma': [132], 'membrane.': [133], 'Mutations': [134], 'other': [136], 'surrounding': [139], 'Phe5': [140, 157, 182], 'also': [141, 161], 'caused': [142], 'increased': [143], 'cell': [144, 245, 287], 'surface': [145, 246], 'but': [149], 'not': [150], 'to': [151, 163, 185, 232, 237], 'same': [153], 'extent': [154], 'as': [155], 'mutation.': [158], 'was': [160, 169, 183, 209, 229, 240, 248], 'localized': [162, 231], 'clathrin': [164], 'lattices': [165], 'colocalization': [168], 'abolished': [170], 'when': [171, 181], 'either': [172], 'first': [174], '13': [175], 'deleted': [179], 'changed': [184], 'alanine.': [186], 'To': [187], 'ascertain': [188], 'whether': [189], 'could': [199], 'function': [200], 'independently': [201], 'structure': [206], 'inserted': [210], 'into': [211], 'tail': [214], 'H1': [217, 223, 251], 'subunit': [218], 'asialoglycoprotein': [221], 'receptor.': [222], 'with': [224, 281], 'predominantly': [230], 'an': [233], 'compartment': [235], 'similar': [236], 'sequestered': [241], 'more': [242], 'than': [247], 'wild-type': [250], 'protein.': [252], 'It': [253], 'is': [254], 'concluded': [255], 'phenylalanine-based': [264], 'motif': [266], 'least': [272], 'part': [274], 'by': [275], 'facilitating': [276], 'interaction': [277], 'endocytic': [282], 'machinery': [283], 'located': [284], 'surface.': [288]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2007143460', 'counts_by_year': [{'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-09-25T01:12:21.483392', 'created_date': '2016-06-24'}