Publication Information

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2770, 2793, 2800, 2837, 2840, 2867, 2919, 2939, 2984, 3004, 3044, 3132, 3237, 3298, 3348, 3373, 3421, 3447, 3467, 3481, 3591, 3614, 3617, 3622, 3647, 3698, 3730, 3749, 3755, 3762, 3779, 3783, 3866, 3896, 3932, 3980, 3992, 4019, 4034, 4043, 4051, 4182, 4206, 4450, 4558, 4708, 4813, 4991, 5047, 5115, 5120, 5149, 5220, 5238, 5278], 'phosphorylation': [13, 788, 794, 984, 1872, 1923, 2156, 2195, 2217, 2227, 2853, 3170, 3923, 4301, 4691, 4764, 4993, 5044], 'Attila': [14, 18, 81, 83, 268, 272, 335, 337, 524, 529], 'Csikász-Nagy': [15, 19, 269, 273, 525], 'Corresponding': [16, 228, 270, 482], 'Author': [17, 229, 271, 483, 522], 'The': [20, 111, 274, 365, 647, 728, 870, 1635, 1727, 1766, 1839, 1857, 1894, 1917, 1934, 2441, 2810, 2860, 2910, 2950, 3066, 3116, 3962, 4056, 4577, 4607, 4733, 4848, 4879, 5010, 5082], 'Microsoft': [21, 112, 275, 366, 546, 648], 'Research––University': [22, 113, 276, 367, 547], 'of': [23, 46, 55, 60, 68, 86, 94, 114, 129, 163, 203, 233, 242, 247, 255, 277, 300, 309, 314, 322, 340, 348, 368, 383, 417, 457, 487, 496, 501, 509, 548, 560, 569, 574, 582, 592, 613, 629, 650, 683, 686, 712, 736, 739, 741, 766, 773, 789, 795, 802, 808, 834, 839, 846, 850, 858, 873, 886, 906, 929, 985, 987, 1027, 1035, 1087, 1101, 1179, 1257, 1290, 1337, 1369, 1441, 1451, 1468, 1475, 1521, 1533, 1549, 1563, 1571, 1614, 1643, 1675, 1697, 1757, 1773, 1781, 1800, 1841, 1848, 1852, 1870, 1876, 1887, 1896, 1907, 1911, 1924, 2017, 2053, 2070, 2093, 2105, 2114, 2178, 2186, 2218, 2228, 2237, 2262, 2264, 2271, 2281, 2290, 2305, 2326, 2333, 2346, 2364, 2375, 2446, 2475, 2478, 2489, 2496, 2522, 2539, 2565, 2578, 2582, 2590, 2599, 2610, 2668, 2699, 2725, 2739, 2766, 2854, 2907, 2931, 2935, 2962, 2974, 3037, 3057, 3068, 3107, 3183, 3203, 3226, 3254, 3265, 3296, 3379, 3398, 3410, 3463, 3476, 3505, 3559, 3580, 3636, 3663, 3676, 3680, 3691, 3707, 3711, 3746, 3758, 3816, 3839, 3863, 3867, 3870, 3886, 3888, 3890, 3894, 3910, 3938, 3958, 3972, 4000, 4017, 4040, 4054, 4064, 4158, 4173, 4194, 4209, 4219, 4227, 4245, 4263, 4275, 4300, 4322, 4333, 4337, 4355, 4383, 4406, 4430, 4455, 4464, 4521, 4540, 4556, 4565, 4595, 4613, 4624, 4679, 4692, 4699, 4710, 4723, 4751, 4765, 4778, 4803, 4822, 4857, 4867, 4897, 4912, 4923, 4947, 4951, 4964, 4986, 4994, 5000, 5012, 5018, 5027, 5045, 5058, 5090, 5102, 5118, 5132, 5141, 5157, 5167, 5175, 5196, 5204, 5213, 5227, 5236, 5252, 5284], 'Trento': [24, 115, 278, 369, 549, 651, 661], 'Centre': [25, 49, 116, 236, 279, 303, 370, 490, 550, 563, 652, 677], 'for': [26, 35, 50, 75, 101, 117, 137, 159, 168, 190, 220, 237, 262, 280, 289, 304, 329, 355, 371, 391, 413, 422, 444, 474, 491, 516, 551, 564, 609, 653, 678, 1288, 1303, 1653, 1794, 1861, 1865, 2013, 2155, 2162, 2268, 2283, 2323, 2561, 2694, 3034, 3406, 3688, 3883, 3989, 3996, 4235, 4586, 4768, 4854, 4989, 5087], 'Computational': [27, 118, 281, 372, 552, 654], 'Systems': [29, 52, 120, 125, 239, 283, 306, 374, 379, 493, 554, 566, 656, 680, 707], 'Biology,': [30, 53, 121, 240, 284, 307, 375, 494, 555, 567, 657, 681], 'Povo': [31, 122, 285, 376, 556], '(Trento),': [32, 123, 286, 377, 557], 'Italy': [33, 124, 287, 378, 558], 'Search': [34, 74, 100, 136, 167, 189, 219, 261, 288, 328, 354, 390, 421, 443, 473, 515], 'more': [36, 76, 102, 138, 169, 191, 221, 263, 290, 330, 356, 392, 423, 445, 475, 517, 3081, 3158, 3364, 3519, 3540, 3724, 3855], 'papers': [37, 77, 103, 139, 170, 192, 222, 264, 291, 331, 357, 393, 424, 446, 476, 518], 'this': [39, 79, 105, 141, 172, 194, 224, 266, 293, 333, 359, 395, 426, 448, 478, 520, 1264, 1317, 1327, 1654, 2355, 2376, 3284, 3656, 5295], 'author': [40, 80, 106, 142, 173, 195, 225, 267, 294, 334, 360, 396, 427, 449, 479, 521], 'Orsolya': [41, 43, 295, 297, 527], 'Kapuy': [42, 44, 296, 298, 4360], 'Department': [45, 59, 85, 202, 232, 246, 299, 313, 339, 456, 486, 500, 682], 'Biochemistry,': [47, 130, 234, 301, 384, 488, 561, 593, 684], 'Oxford': [48, 235, 302, 489, 562, 691], 'Integrative': [51, 238, 305, 492, 565, 679, 4261], 'University': [54, 67, 93, 162, 241, 254, 308, 321, 347, 416, 495, 508, 568, 581, 612, 685, 4018], 'Oxford,': [56, 57, 243, 244, 310, 311, 497, 498, 570, 571, 687], 'UK': [58, 183, 188, 245, 312, 437, 442, 499, 572, 622, 627], 'Applied': [61, 87, 248, 315, 341, 502, 575], 'Biotechnology': [62, 88, 249, 316, 342, 503, 576], 'Food': [64, 90, 251, 318, 344, 505, 578], 'Science,': [65, 91, 252, 319, 345, 506, 579], 'Budapest': [66, 92, 253, 320, 346, 507, 580], 'Technology': [69, 95, 256, 323, 349, 510, 583], 'Economics,': [71, 97, 258, 325, 351, 512, 585], 'Budapest,': [72, 98, 259, 326, 352, 513, 586], 'Hungary': [73, 99, 135, 260, 327, 353, 389, 514, 587, 598], 'Tóth': [82, 84, 336, 338], 'Csaba': [107, 109, 361, 363, 531], 'Pál': [108, 110, 362, 364], 'Biology': [126, 151, 380, 405, 589, 601, 708], 'Unit,': [127, 381, 590], 'Institute': [128, 212, 382, 466, 591, 638], 'Biological': [131, 204, 385, 458, 594, 630], 'Research': [132, 182, 185, 386, 436, 439, 595, 621, 624, 4012, 4020, 4026], 'Center,': [133, 387, 596], 'Szeged,': [134, 388, 597], 'Lars': [143, 146, 397, 400, 533], 'Juhl': [144, 147, 398, 401, 534], 'Jensen': [145, 148, 399, 402, 1205, 1227, 4412, 4543, 4545], 'European': [149, 403, 4025, 4031], 'Molecular': [150, 404, 600, 706], 'Laboratory,': [152, 180, 406, 434, 602, 619], 'Heidelberg,': [153, 407, 603], 'Germany': [154, 408, 604], 'Novo': [155, 409], 'Nordisk': [156, 410, 606], 'Foundation': [157, 411, 607, 4048], 'Center': [158, 412, 608], 'Protein': [160, 414, 610], 'Research,': [161, 415, 611], 'Copenhagen,': [164, 165, 418, 419, 614, 615], 'Denmark': [166, 420, 616], 'Frank': [174, 176, 428, 430, 536], 'Uhlmann': [175, 177, 429, 431], 'Chromosome': [178, 432], 'Segregation': [179, 433, 618], 'Cancer': [181, 435, 620], 'London': [184, 438, 623], 'Institute,': [186, 209, 440, 463, 625, 635], 'London,': [187, 441, 626], 'John': [196, 199, 450, 453, 538], 'J': [197, 200, 451, 454, 539, 4240, 4398, 4459, 4746, 5152], 'Tyson': [198, 201, 452, 455, 948, 4258, 4364, 4783, 5105, 5135, 5160], 'Sciences': [205, 459, 631], 'Virginia': [207, 210, 461, 464, 633, 636], 'Bioinformatics': [208, 462, 634, 3764], 'Polytechnic': [211, 465, 637], '&': [213, 467, 639, 726], 'State': [214, 468, 640], 'University,': [215, 469, 641], 'Blacksburg,': [216, 470, 642], 'VA,': [217, 471, 643], 'USA': [218, 472, 644, 4170, 4319, 4720], 'Béla': [226, 230, 480, 484, 542], 'Novák': [227, 231, 481, 485, 543], 'Information': [523, 4067, 4136], '1,': [526], 'Kapuy2,3,': [528], 'Tóth3,': [530], 'Pál1,4,': [532], 'Jensen5,6,': [535], 'Uhlmann7,': [537], 'Tyson8': [540], '2,3': [544], '1The': [545], '2Department': [559], '3Department': [573], '4Systems': [588], '5European': [599], '6Novo': [605], '7Chromosome': [617], '8Department': [628], '*Corresponding': [645], 'authors.': [646], 'Research—University': [649], 'Piazza': [658], 'Manci': [659], '17,': [660], '38100,': [662], 'Italy.': [663], 'Tel.:': [664, 695], '+39': [665, 670], '046': [666, 671], '188': [667, 672], '2824;': [668], 'Fax:': [669, 699], '2814;': [673], 'E-mail:': [674, 703], '[email': [675, 704], 'protected]': [676, 705], 'South': [688], 'Parks': [689], 'Road,': [690], 'OX1': [692], '3QU,': [693], 'UK.': [694], '+44': [696, 700], '1865': [697, 701], '613216;': [698], '613213;': [702], '(2009)5:236https://doi.org/10.1038/msb.2008.73': [709], 'PDFDownload': [710], 'PDF': [711], 'article': [713], 'text': [714], 'main': [716], 'figures.': [717], 'ToolsAdd': [718], 'to': [719, 882, 1091, 1126, 1158, 1251, 1279, 1314, 1360, 1423, 1577, 1618, 1760, 2049, 2191, 2259, 2394, 2412, 2516, 2532, 2721, 2806, 2826, 2892, 3051, 3079, 3394, 3414, 3536, 3576, 3950, 3978, 4348, 4795, 4888], 'favoritesDownload': [720], 'CitationsTrack': [721], 'CitationsPermissions': [722], 'ShareFacebookTwitterLinked': [723], 'InMendeleyWechatReddit': [724], 'Figures': [725], 'Info': [727], 'eukaryotic': [729, 896, 3526, 3638, 5143], 'cell': [730, 747, 836, 887, 908, 958, 978, 1108, 1131, 1163, 1173, 1183, 1199, 1217, 1238, 1244, 1304, 1429, 1469, 1500, 1514, 1659, 1678, 1719, 1733, 1761, 1774, 1811, 1837, 2125, 2133, 2181, 2252, 2334, 2371, 2514, 2594, 2643, 3412, 3422, 3468, 3509, 3549, 3583, 3666, 3692, 3712, 3750, 3960, 4210, 4232, 4264, 4349, 4425, 4917, 4948, 5144, 5169, 5276], 'requires': [732], 'precise': [733], 'temporal': [734, 892, 2473, 3503, 3588, 3709], 'coordination': [735], 'the': [737, 760, 790, 796, 803, 835, 840, 847, 851, 907, 992, 1000, 1019, 1024, 1032, 1046, 1056, 1063, 1068, 1078, 1085, 1092, 1099, 1198, 1216, 1232, 1266, 1268, 1320, 1332, 1338, 1354, 1370, 1396, 1428, 1442, 1473, 1487, 1522, 1531, 1547, 1588, 1592, 1612, 1666, 1673, 1695, 1698, 1739, 1778, 1792, 1807, 1836, 1846, 1849, 1853, 1868, 1874, 1879, 1884, 1901, 1908, 1912, 1929, 1955, 1960, 2075, 2098, 2106, 2115, 2123, 2147, 2183, 2187, 2204, 2238, 2251, 2260, 2269, 2274, 2284, 2311, 2347, 2368, 2379, 2383, 2397, 2417, 2450, 2460, 2471, 2484, 2502, 2523, 2537, 2540, 2563, 2593, 2597, 2666, 2711, 2735, 2779, 2788, 2816, 2963, 2972, 3146, 3154, 3184, 3188, 3206, 3245, 3259, 3293, 3369, 3377, 3385, 3388, 3399, 3411, 3425, 3488, 3508, 3581, 3606, 3632, 3671, 3689, 3708, 3744, 3753, 3789, 3844, 3852, 3861, 3868, 3884, 3891, 3902, 3907, 3918, 3935, 3943, 3959, 3973, 4001, 4030, 4037, 4044, 4185, 4207, 4334, 4370, 4423, 4453, 4511, 4534, 4614, 4690, 4711, 4886, 4952, 5015, 5088, 5124, 5142, 5168, 5197, 5214, 5275], 'activities': [738, 922, 2322], 'hundreds': [740], "'executor'": [742], 'proteins': [743, 964, 1041, 1051, 1128, 1192, 1210, 1492, 1505, 1667, 1676, 1696, 1710, 1744, 2108, 3043, 3059, 3232, 3616, 3827, 4304, 4858], '(EPs)': [744, 965], 'involved': [745, 1272, 1390, 1416, 1668, 3240, 3517, 3722, 3742], 'in': [746, 758, 890, 917, 996, 1004, 1038, 1045, 1055, 1103, 1118, 1169, 1273, 1283, 1391, 1417, 1478, 1591, 1669, 1832, 2122, 2164, 2212, 2329, 2351, 2401, 2429, 2435, 2534, 2543, 2592, 2782, 2942, 2967, 3109, 3241, 3274, 3289, 3307, 3322, 3331, 3424, 3435, 3442, 3495, 3507, 3518, 3532, 3547, 3566, 3585, 3599, 3625, 3654, 3695, 3723, 3743, 3800, 4229, 4267, 4340, 4375, 4452, 4673, 4689, 4743, 4772, 4891, 5014, 5021, 5052, 5094, 5123, 5246], 'growth': [748], 'division.': [750, 1184, 4211], 'Cyclin-dependent': [751, 918], 'protein': [752, 919, 1149, 1356, 1398, 1930, 2755, 3872, 5217], 'kinases': [753, 3208, 4205, 5218, 5242], '(Cdks)': [754], 'play': [755, 1831, 2118, 3302, 3492, 3544], 'central': [756], 'roles': [757, 1100, 2121, 3441, 3494, 3546, 4985], 'regulating': [759], 'production,': [761], 'activation,': [762], 'inactivation': [763], 'destruction': [765], 'these': [767, 809, 1413, 1795, 1801, 1828, 1897, 2120, 2551, 3058, 3353, 3443, 3484, 3513], 'EPs.': [768, 1502, 3897], 'From': [769, 2550], 'genome-scale': [770], 'data': [771], 'sets': [772], 'budding': [774, 997, 1284, 1339, 1523, 2369, 3110, 3290, 3420, 3436, 3759, 4268, 4773, 5053, 5247], 'yeast,': [775, 3291, 3568], 'we': [776, 823, 1012, 1110, 1329, 1545, 1656, 1749, 1822, 2136, 2357, 2528, 2553, 2607, 2955, 3195, 3342, 3451, 3460, 3802, 3905, 3920, 3933], 'identify': [777, 2555, 3052], '126': [778, 1388, 1414], 'EPs': [779, 810, 830, 859, 1802, 1813, 1984, 2003, 2179, 2560, 3316], 'that': [780, 799, 806, 825, 860, 923, 1018, 1042, 1052, 1112, 1129, 1193, 1211, 1236, 1253, 1394, 1464, 1486, 1658, 1708, 1751, 2103, 2505, 2851, 2903, 2954, 2979, 3020, 3073, 3197, 3283, 3317, 3345, 3360, 3431, 3471, 3487, 3512, 3528, 3543, 3631, 3648, 3670, 3728, 3804, 3922, 4059], 'are': [781, 861, 924, 954, 1156, 1187, 1191, 1194, 1212, 1219, 1259, 1271, 1372, 1421, 1506, 1662, 1711, 1736, 1753, 1797, 1814, 2337, 2349, 2776, 2798, 2959, 3064, 3318, 3363, 3392, 3403, 3439, 3453, 3472, 3515, 3739, 3857, 4793], 'regulated': [782, 812], 'Cdk1': [784, 983, 1060, 1073, 1185, 1291, 1363, 1384, 1401, 1410, 2009, 2095, 2804, 2852, 2870, 3002, 3015, 3061, 3243, 3255, 3766, 3810, 3899, 3916, 3963], 'both': [785, 1509, 4448], 'through': [786, 793, 899, 1835, 2920], 'direct': [787, 1922, 2184, 2216, 3474], 'EP': [791, 1915, 1925, 2058, 2081, 2165, 2220, 2239, 2321, 2427, 2447, 3911, 3928, 3939, 3953], 'factors': [798, 1234], 'control': [800, 3211, 3475, 3645, 4266], 'expression': [801, 1241, 2895, 4612], 'EP,': [804, 3903, 3919], 'so': [805, 3205], 'each': [807, 1543, 2513], 'is': [811, 912, 980, 1249, 1265, 1312, 1382, 1395, 1399, 1408, 1462, 1472, 1622, 1730, 1777, 1788, 1992, 2011, 2059, 2082, 2189, 2702, 2707, 2719, 2865, 2881, 2914, 2999, 3012, 3094, 3103, 3156, 3199, 3280, 3287, 3328, 3337, 3383, 3574, 3808, 3819, 3929, 4343], 'a': [814, 878, 884, 927, 988, 1028, 1145, 1362, 1383, 1400, 1409, 1447, 1465, 1476, 1565, 1568, 1605, 1619, 1630, 1995, 2014, 2054, 2056, 2067, 2079, 2090, 2142, 2174, 2193, 2200, 2213, 2232, 2361, 2493, 2616, 2629, 2642, 2691, 2833, 2932, 3017, 3097, 3104, 3123, 3151, 3214, 3222, 3263, 3304, 3407, 3501, 3569, 3586, 3642, 3651, 3664, 3685, 3704, 3805, 3809, 3969, 3997, 4230, 4236, 4394, 4739, 4850, 5085], 'loop': [816, 1030, 3120, 3149, 3286, 4580, 4713, 4736], '(FFL)': [817], 'from': [818, 1121, 2141, 3172, 3770, 3788, 3843, 3968, 4009, 4305, 4859], 'Cdk1.': [819, 2830, 3822, 5200], 'By': [820, 3144], 'mathematical': [821], 'modelling,': [822], 'show': [824, 1657, 2608], 'such': [826, 1176, 3040, 3233, 3303], 'FFLs': [827, 864, 874, 1102, 1113, 1752, 1975, 2023, 2130, 2384, 2443, 2469, 2482, 2557, 2767, 2953, 2980, 3031, 3075, 3314, 3362, 3402, 3434, 3455, 3478, 3491, 3514, 3649, 3677, 3719, 3738], 'can': [828, 1939, 2249, 3351, 3611, 3618, 4581], 'activate': [829], 'at': [831, 1254, 1319, 1378, 1404, 1994, 2396, 2449, 2459, 2741, 3130, 3137, 3244, 3752, 3813, 3955], 'different': [832, 1699, 2279, 3018, 3956], 'phases': [833, 905, 2336, 3957], 'depending': [838], 'effective': [841, 1957], 'signs': [842, 1847, 1899, 1958, 2538, 2564, 2774, 3862], '(+': [843, 1860, 2423, 2465, 2625, 2638], 'or': [844, 1182, 1352, 1366, 1376, 1863, 1890, 1905, 1931, 2295, 2299, 3330, 3539], '−)': [845], 'regulatory': [848, 1124, 1165, 1444, 1481, 1700, 1768, 2541, 3083, 3390, 3726, 3975, 4671, 5092, 5119], 'steps': [849], 'FFL.': [852, 3217], 'We': [853, 1386, 1671, 1706, 2101, 2145, 2254, 2373, 2575, 3310, 3629, 3668, 3876, 3984], 'provide': [854, 1650], 'several': [855], 'case': [856, 2261, 2270, 2285, 2667, 2973, 3067, 3378], 'studies': [857], 'controlled': [862, 981], 'exactly': [865, 2119], 'as': [866, 1160, 1177, 1190, 1300, 1302, 2378, 2385, 2406, 2690, 2705, 2752, 3041, 3122, 3234, 3678, 3703, 3940, 4738], 'our': [867, 1786, 2111, 2256, 2544, 2600, 2670, 2697], 'models': [868], 'predict.': [869], 'signal-transduction': [871, 1829, 2964], 'properties': [872, 1978], 'allow': [875], 'one': [876, 1380, 1406, 3181, 3553, 3602, 3815], '(or': [877], 'few)': [879], 'Cdk': [880, 952, 1136, 1146, 1170, 1221, 1537, 1758, 1927, 1990, 2063, 2072, 2086, 2222, 2317, 2490, 2917, 3169, 3326, 3335, 3498, 3682, 3974], 'signal(s)': [881], 'drive': [883, 1237, 2425, 2444, 3577, 3612], 'host': [885], 'responses': [889, 960], 'correct': [891, 3426, 3502], 'sequence.': [893], 'Introduction': [894], 'A': [895, 1081, 4179, 4438, 4788, 5210], "cell's": [897, 2524], 'progression': [898, 1834], 'G1,': [900], 'S,': [901, 4415, 4551, 4569, 4703, 4727, 4757, 4904, 5004, 5031, 5037, 5068], 'G2': [902], 'M': [904, 3276, 4978], 'replication': [909, 2862, 3465, 4237, 4771, 5020, 5051, 5245], 'division': [910, 979, 2644, 3469, 3751], 'orchestrated': [913], 'large-amplitude': [915], 'fluctuations': [916, 1168], 'kinase': [920, 2791, 4446, 4616, 4694, 4882, 5199], '(Cdk)': [921], 'generated': [925, 3967], 'series': [928], 'coupled': [930], 'positive': [931, 3267], 'negative': [933], 'feedback': [934, 3099, 3119, 3148, 3268, 3285, 4532, 4911], '(Novak': [936], 'et': [937, 941, 945, 967, 971, 1015, 1202, 1206, 1224, 1228, 1293, 1308, 1687, 1691, 1980, 2030, 2038, 2242, 2621, 2634, 2662, 2687, 2745, 2761, 2847, 2872, 2876, 2897, 2925, 3008, 3113, 3141, 3175, 3250, 3775, 3793, 3833, 3848, 4667], 'al,': [938, 942, 946, 968, 972, 1016, 1203, 1207, 1225, 1229, 1294, 1309, 1688, 1692, 1981, 2031, 2039, 2243, 2622, 2635, 2663, 2688, 2746, 2762, 2848, 2873, 2877, 2898, 2926, 3009, 3114, 3142, 3176, 3251, 3776, 3794, 3849], '2007;': [939, 3006], 'Holt': [940, 4524], '2008;': [943, 947, 2036], 'Skotheim': [944, 4900], 'Novak,': [950, 3981], '2008).': [951, 2040], 'signals': [953, 1120, 1166, 3683], 'transduced': [955], 'into': [956, 1342, 1528, 1806, 1942, 2492, 3247, 3262, 3500, 3660], 'appropriate': [957], 'specific': [962], 'executor': [963, 1148], '(Sutani': [966], '1999;': [969], 'Tanaka': [970, 3007, 5003, 5030], '2007a)': [973], '(Box': [974, 1276, 1764, 2388, 3674], '1).': [975, 1277, 1765, 2389], 'For': [976, 1542, 1553, 1594, 2970, 3913], 'example,': [977, 2971], 'components': [986, 3818], 'signalling': [989], 'pathway': [990], 'called': [991], "'mitotic": [993], 'exit': [994, 2408, 2812, 3139, 3624, 5216], "network'": [995, 1003], 'yeast': [998, 1006, 1285, 1340, 1524, 2116, 2124, 2370, 3111, 3437, 4377, 4424, 4441, 4953, 4981, 5271], "'septation": [1001], 'initiation': [1002, 1021, 1065, 1178, 2743, 3745, 4372, 5016], 'fission': [1005, 3567, 4376, 4440], '(Bardin': [1007], 'Amon,': [1009, 2649], '2001).': [1010, 3982], 'Recently,': [1011], 'showed': [1013], '(Csikasz-Nagy': [1014], '2007)': [1017, 2751], 'septation': [1020, 1064, 4371], 'network': [1022, 1047, 1057, 1069, 1345, 3521, 4373, 4714], 'has': [1023, 1357, 2231, 2683, 2832, 2889, 3162, 3699], 'characteristic': [1025], 'topology': [1026, 1532, 1769], '(FFL):': [1031], 'high': [1033, 1449, 1771, 1996, 2094], 'level': [1034, 1997], 'Cdk1–cyclin': [1036, 1122, 2365, 2390], 'B': [1037, 2366, 2391, 3239, 4367, 4444, 4943, 5110, 5138, 5163, 5268], 'mitosis': [1039, 2402, 2409, 3248, 4451], 'activates': [1040, 1928, 3901], 'function': [1043, 1053, 1159, 1840, 4709], 'early': [1044, 3696], '(sensors)': [1048], 'inactivates': [1050, 3917], 'late': [1054], '(executors).': [1058], 'High': [1059], 'activity': [1061, 1074, 1875, 1991, 2010, 2064, 2073, 2087, 2096, 2392, 2428, 2448, 2491, 3128, 3135, 3327, 3336, 3573], 'primes': [1062], 'network,': [1066], 'but': [1067, 2226, 2823, 3511, 4346], 'cannot': [1070, 2843], "'fire'": [1071], 'until': [1072], 'falls': [1075, 2088, 2404], 'releases': [1077], 'inhibitory': [1079], 'arm.': [1080, 2206], 'similar': [1082, 3223], 'FFL': [1083, 1275, 1480, 1843, 1913, 2149, 2188, 2324, 2545, 2614, 2627, 2640, 2655, 2712, 3093, 3261, 3609], 'controls': [1084, 3694, 4885], 'onset': [1086], 'DNA': [1088, 1105, 1180, 2861, 3038, 3464, 3747, 4228, 4770, 5019, 5050, 5244], 'synthesis,': [1089], 'according': [1090], "'licensing": [1093], "factor'": [1094], 'hypothesis': [1095, 1318], '(Blow,': [1096], '1993).': [1097], 'Recognizing': [1098], 'executing': [1104], 'synthesis': [1106, 1181, 2289, 3748], 'division,': [1109], 'hypothesized': [1111], 'might': [1114, 2131, 3032, 3343], 'be': [1115, 1243, 1361, 1424, 1435, 1498, 1578, 1940, 1986, 2005, 2570, 2714, 2722, 2827, 2844, 2982, 3049, 3077, 3272, 3537, 3721], 'common': [1116, 3634], 'motifs': [1117, 1445, 2150, 2325, 2546], 'transmitting': [1119], 'master': [1123], 'complexes': [1125], 'target': [1127, 1402], 'execute': [1130], 'events.': [1133, 3551, 3714], 'Box': [1134], '1': [1135], 'signal': [1137, 2026, 2700, 3366, 3659], 'transduction': [1138, 2701], 'Feed-forward': [1142], 'loops,': [1143, 3269], 'involving': [1144, 2558], 'substrate': [1147, 3811], '(EP)': [1150], 'its': [1152, 2229, 2754, 2794, 2841, 2857, 2921, 3022, 3227, 3556, 3817], 'factor': [1154, 2819, 4609], '(TF),': [1155], 'proposed': [1157, 2571, 2685, 2891], 'transducers': [1161, 1756, 3367, 3679], 'between': [1162], '(periodic': [1167], 'activity)': [1171], 'responses,': [1175], 'substrates': [1186, 1222, 3767], 'potential': [1188, 2692], 'EPs,': [1189, 3560], 'periodically': [1195, 1213, 1425, 1452, 1489, 1510, 1550], 'expressed': [1196, 1214, 1426, 1453, 3320], 'during': [1197, 1215, 1427, 2367, 2512, 4422], '(Spellman': [1201], '1998;': [1204], '2006).': [1208, 1230, 2899, 3795], 'Intriguingly,': [1209], 'often': [1220, 3516], '(Ubersax': [1223, 1292, 3774], '2003;': [1226, 1295, 2032, 3777], 'Furthermore,': [1231, 3459], '(TFs)': [1235], 'cycle-dependent': [1239], 'gene': [1240, 1371, 1477, 1566, 1716, 1892, 2679], 'must': [1242, 1823, 2506], 'cycle-regulated': [1245, 4949], 'themselves,': [1246], 'it': [1248, 1311, 1461, 3011, 3279, 3941], 'reasonable': [1250, 3686], 'suspect': [1252], 'least': [1255, 1379, 1405, 3814], 'some': [1256, 2535, 2585], 'them': [1258], 'phosphorylated': [1260, 2799, 2866, 3013, 3820, 3927], 'Cdks.': [1262], 'Wherever': [1263], 'case,': [1267], 'Cdk–TF–EP': [1269], 'trio': [1270], 'an': [1274, 1392, 1479, 1581, 1639, 1842, 2219, 2611, 2624, 2637, 2652, 2657, 2708, 2723, 3053, 3089, 3092, 3201, 3626], 'Owing': [1278], 'large-scale': [1280, 3772], 'experimental': [1281, 2732], 'screens': [1282, 3773], '(Saccharomyces': [1286], 'cerevisiae)': [1287], 'targets': [1289, 3785], 'Loog': [1296, 3778, 4682], 'Morgan,': [1298, 3780], '2005),': [1299], 'well': [1301, 2753], 'TFs': [1306, 1368, 1793, 3782, 3798, 3895], '(Lee': [1307], '2002),': [1310], 'possible': [1313, 1826, 1936], 'systematically': [1315], 'test': [1316], 'genome-wide': [1321], 'scale.': [1322], 'Results': [1323], 'discussion': [1325], 'To': [1326, 1649, 2127, 2172], 'end,': [1328], 'classified': [1330], 'all': [1331, 1602, 2566, 2579, 3168, 3525, 3578], '4691': [1333], 'verified': [1334, 1519], 'protein-coding': [1335], 'genes': [1336, 1389, 1415, 1454, 1512, 1796, 3840, 4950, 5273], 'genome': [1341, 1525], '6': [1343], 'non-overlapping': [1344], 'topologies': [1346, 1701, 3350, 3371, 3727], '(Figure': [1347, 1455, 1722, 2167, 2602, 2976, 3070, 3086, 3219, 3445, 3479, 3596], '1A)': [1348], 'based': [1349], 'on': [1350, 1575, 1703, 1845, 1873, 1914, 1959, 2199, 2235, 2734, 3016, 3126, 3641, 3859, 4303], 'whether': [1351, 1365, 1375, 1883, 1921], 'not': [1353, 1367, 1377, 3200, 3281, 3301, 3384, 4344], 'encoded': [1355, 1397], 'been': [1358, 2684, 2890, 3163, 3530], 'reported': [1359], 'substrate,': [1364], 'known': [1373, 3433], 'TF': [1381, 1407, 1888, 2230, 2287, 2693, 2884, 3806], 'target.': [1385, 1411], 'identified': [1387, 2109, 3829], 'FFL,': [1393, 2282, 3153, 3185], 'Of': [1412, 2041], 'FFLs,': [1418, 1950, 1967, 2419, 2583, 3381], '68': [1419, 1488], '(54%)': [1420], 'found': [1422, 1579, 1707, 2576, 3461], 'cycle,': [1430, 2182, 3510], 'whereas': [1431], 'only': [1432, 1988, 2007, 2048, 2510, 3386, 3405], '13': [1433], 'would': [1434, 1985, 2004], 'expected': [1436, 1640, 2190], 'chance': [1438], '(P<10−28).': [1439], 'None': [1440], 'other': [1443, 1767, 2940, 3035], 'shows': [1446], 'comparably': [1448], 'ratio': [1450, 1642], '1A;': [1456], 'Supplementary': [1457, 1556, 1598, 1724, 2169, 2275, 2783, 2943, 3853, 4068, 4074, 4080, 4086, 4092, 4098, 4104, 4110, 4116, 4123, 4129, 4135], 'Table': [1458, 1494, 1557, 1599, 1725, 1746, 2170, 2308, 2548, 2573, 2784, 2944, 2992, 3457, 3881, 4093, 4099, 4105, 4111, 4117, 4124, 4130], 'S1).': [1459], 'Thus,': [1460, 1748], 'clear': [1463, 3282], 'strong': [1466, 2051, 3305], 'predictor': [1467], 'periodicity': [1471], 'involvement': [1474], 'motif.': [1482, 4715], 'This': [1483, 2728, 3160, 4003], 'observation': [1484], 'suggests': [1485, 2995, 3072, 3359], 'transcribed,': [1490], 'FFL-regulated': [1491, 1709, 1743, 1808, 2107], '(Supplementary': [1493, 1745, 2307, 2547, 2572, 2991, 3456, 3880], 'S2)': [1495], 'may': [1496, 2046, 2569, 2981, 3048, 3076, 3271, 3554, 3720], 'indeed': [1497, 1754, 1815, 3210, 3448], 'key': [1499], 'Figure': [1503, 1704, 2245, 2352, 2605, 2764, 3340, 4069, 4075, 4081, 4087], '1.FFL-regulated': [1504], 'over-represented': [1507, 1664, 1713, 1737], 'among': [1508, 1665, 1694, 1714, 1738], 'transcribed': [1511], 'cycle-related': [1515, 1660, 1775], 'genes.': [1516, 1784, 4587], '(A)': [1517, 2277, 2786], 'All': [1518], 'ORFs': [1520], 'were': [1526, 3768, 3786, 3828, 3841, 3948], 'distributed': [1527], 'groups': [1529], 'their': [1534, 2139, 3732, 3784], '(Cdk1)': [1538], 'factors.': [1541], 'group,': [1544], 'report': [1546], 'number': [1548], 'transcribed/total': [1551], 'proteins.': [1552, 2480], 'details,': [1554], 'see': [1555, 1597, 2128, 2273], 'S1.': [1558], '(B)': [1559, 2302, 2809], 'Odds': [1560], 'ratios': [1561], '(observed/expected)': [1562], 'finding': [1564], 'with': [1567, 1580, 1677, 1718, 1742, 1770, 1818, 1954, 1971, 2293, 2821, 2886, 3096, 3315, 4393], 'certain': [1569], 'type': [1570], '(as': [1573], 'explained': [1574], '(A))': [1576], 'MIPS': [1582, 1682, 3836], 'functional': [1583, 1683, 3294, 4851], 'category': [1584, 1684], 'term': [1585], 'given': [1586, 3858], 'colour': [1589, 2328], 'code': [1590], 'legend.': [1593], 'detailed': [1595], 'statistics,': [1596], 'S3.': [1600], 'On': [1601], 'six': [1603], 'panels,': [1604], 'single': [1606, 2175, 3570, 3643, 3657, 4231, 4395, 4439], 'star': [1607], 'denotes': [1608, 1629], 'those': [1609], 'cases': [1610, 3914], 'where': [1611, 2286, 3091, 3292, 3915], 'probability': [1613, 1631], 'random': [1615], 'appearance': [1616, 2474, 2591], '(according': [1617], 'binomial': [1620], 'distribution)': [1621], 'less': [1623, 1632, 3191], 'than': [1624, 1633, 2203, 3368], '10−3,': [1625], 'two': [1627, 1898, 1943, 2503, 3025, 3189, 3389, 3538, 3771], 'stars': [1628], '10−6.': [1634], 'dashed': [1636], 'line': [1637], 'indicates': [1638, 1867, 1882, 1900, 1920], 'odds': [1641], '1.': [1644], 'Download': [1645, 1647, 2340, 2342, 2946, 2948], 'figure': [1646, 2341, 2947], 'PowerPoint': [1648, 2343, 2949], 'further': [1651], 'support': [1652], 'assertion,': [1655], 'functions': [1661, 1721, 1735, 1776, 3121, 4585], 'significantly': [1663, 1712, 1816], 'FFLs.': [1670, 2936, 3028, 3564], 'checked': [1672], 'distribution': [1674], '(and': [1680], 'related)': [1681], 'annotations': [1685, 3838], '(Ruepp': [1686], '2004;': [1689], 'Guldener': [1690, 4467, 4839], '2005)': [1693], 'established': [1702], '1A.': [1705], 'most': [1715, 1799, 3432, 3449], 'classes': [1717, 1944], '1B;': [1723], 'S3).': [1726], 'converse': [1728], 'statement': [1729], 'also': [1731, 2338], 'true:': [1732], 'terms': [1740], 'associated': [1741, 1817, 2885, 3312], 'S4).': [1747], 'conclude': [1750, 3344, 3669], 'important': [1755, 2586, 3273, 3493], "'signals'": [1759], "'responses'": [1763], 'over-representation': [1772], 'small': [1779], 'group': [1780], "'only": [1782, 2674, 3346], "Cdk'-regulated": [1783], 'If': [1785, 1810, 2696, 3898], 'conclusion': [1787], 'correct,': [1789, 2703], 'then,': [1790, 2704], 'once': [1791, 2508, 2511], 'discovered,': [1798], 'will': [1803], 'fall': [1804, 2488], 'disproportionately': [1805], 'group.': [1809], 'FFL-regulatory': [1819], 'topologies,': [1820], 'then': [1821, 3904], 'ask': [1824], 'what': [1825], 'function(s)': [1827], 'pathways': [1830, 5122], 'orchestrating': [1833], 'cycle.': [1838, 2126, 2253, 2372, 3667, 3961, 4426, 5170], 'depends': [1844], 'three': [1850, 2567], 'links': [1851, 2568], 'motif': [1854], '(±': [1855], '±/±).': [1856], 'first': [1858, 2137], 'sign': [1859, 1881, 1919, 1937], 'activation': [1862, 2177, 2298, 3056, 3397], '−': [1864, 2296], 'inhibition)': [1866, 1906], 'effect': [1869, 1903, 2234, 3869], 'Cdk-mediated': [1871], 'TF,': [1877, 2922], 'second': [1880], 'active': [1885, 1987, 2006, 3892, 3908, 3945], 'form': [1886, 3909], 'upregulates': [1889, 2288, 2905], 'downregulates': [1891], 'expression.': [1893, 2727], 'product': [1895], 'net': [1902], '(activation': [1904], "'long": [1909], "arm'": [1910], 'activity.': [1916], 'third': [1918], 'inhibits': [1932], 'it.': [1933], 'eight': [1935, 2148, 2580, 2951, 3489], 'combinations': [1938], 'divided': [1941], '(Mangan': [1945, 1979, 3372], 'Alon,': [1947, 3374], '2003):': [1948, 1982], 'coherent': [1949, 2418, 3152, 3216, 3260, 3313, 3361, 4734, 4916], '(±±/+)': [1951, 1983], '(∓±/−)': [1953, 2002], 'same': [1956, 2327, 2817], 'long': [1961], 'short': [1963, 3408], 'arms': [1964, 3391], 'incoherent': [1966, 2442, 3380, 3454, 3477, 3737, 4578], '(±±/−)': [1968, 2080], '(∓±/+)': [1970, 2057], 'opposite': [1972], 'signs.': [1973], 'Coherent': [1974, 2468], 'have': [1976, 2024, 2192, 2956, 3311, 3529, 3555, 4061], 'noise-filtering': [1977], 'when': [1989, 2008, 2062, 2085], 'sustained': [1993, 2426], '(in': [1998, 2019, 2359], 'S+G2+M': [1999, 2436, 3332], 'phase),': [2000], 'absent': [2012], 'prolonged': [2015, 2068, 2091], 'period': [2016, 2069, 2092, 3409], 'time': [2018, 3964], 'G1': [2020, 2413, 2430, 2617, 2911, 3323, 4456, 4887, 4913], 'phase).': [2021], 'Incoherent': [2022, 2481, 3401], 'rich': [2025], 'response': [2027], 'capabilities': [2028], '(Tyson': [2029, 3979], 'Csikasz-Nagy': [2033, 4252, 4358, 4386, 4787], 'Soyer,': [2035], 'Kaplan': [2037, 4568], 'particular': [2042], 'relevance': [2043], 'here,': [2044], 'they': [2045, 3063, 4060], 'respond': [2047], 'sufficiently': [2050], 'bursts': [2052, 2445], 'signal:': [2055], 'activated': [2060, 2083, 2802, 2868, 3000, 3404, 3562], 'transiently': [2061, 2084], 'rises': [2065], 'after': [2066, 2089, 2997], 'low': [2071], '(at': [2074, 2097], 'G1/S': [2076, 2398, 2451, 3754], 'transition),': [2077], 'M/G1': [2099, 2461, 3756], 'transition).': [2100], 'propose': [2102], 'many': [2104, 3797], 'bioinformatics': [2112], 'survey': [2113], 'genome/proteome': [2117], 'how': [2129, 3601], 'regulate': [2132, 2250, 2893, 5274], 'events,': [2135], 'study': [2138, 4004], 'dynamics': [2140, 4392, 5117], 'theoretical': [2143], 'perspective.': [2144], 'model': [2146, 2348, 2901, 3971], 'using': [2151], 'ordinary': [2152], 'differential': [2153, 2160, 3878], 'equations': [2154, 2161, 2306, 3879], 'reactions': [2157], 'delay': [2159, 4741], 'changes': [2163], 'concentrations': [2166, 3889], '2A;': [2168], 'S5).': [2171], 'implement': [2173], 'transient': [2176, 3055, 3396], 'per': [2180], 'arm': [2185], 'lower': [2194], 'threshold': [2196], 'operate': [2198, 3033], 'faster': [2201], 'timescale': [2202, 2208], 'indirect': [2205], 'These': [2207], 'differences': [2209], 'arise': [2210], 'naturally': [2211], 'phosphorylation-transcription': [2214], 'FFL:': [2215], 'happens': [2223], 'within': [2224, 3150], 'seconds,': [2225], 'delayed': [2233], 'production': [2236, 2906], '(timescale∼minutes)': [2240], '(Adelman': [2241], '2002).': [2244, 2763], '2.Four': [2246], 'limit': [2255], 'attention': [2257], 'here': [2258], 'upregulation': [2263], 'TF;': [2267], 'downregulation,': [2272], 'information.': [2276], 'Four': [2278], 'types': [2280, 2581], 'EP.': [2291, 3400], 'Arrows': [2292], '+': [2294], 'represent': [2297], 'inhibition,': [2300], 'respectively.': [2301, 2440], 'Computer': [2303], 'simulations': [2304], 'S5)': [2309], 'describing': [2310], 'interactions': [2312], 'diagrammed': [2313], 'above.': [2314], 'Black': [2315], 'line:': [2316], 'activity;': [2318], 'coloured': [2319], 'lines:': [2320], '(A).': [2330], 'Proposed': [2331], 'borders': [2332], 'indicated.': [2339], 'Simulation': [2344], 'results': [2345, 2733], 'shown': [2350], '2B.': [2353], 'In': [2354, 2604, 2665, 3193, 3376, 3524, 3715, 3823, 3851], 'figure,': [2356], 'plot': [2358, 3906, 3934], 'black)': [2360], 'typical': [2362], 'trajectory': [2363, 2377], 'think': [2374], "'signal": [2380, 2386], "generator'": [2381], "transducers'": [2387], 'begins': [2393], 'rise': [2395, 2486], 'transition,': [2399], 'peaks': [2400, 3954], 'rapidly': [2405, 3930], 'cells': [2407, 3438, 3639], 'return': [2411], 'phase.': [2414, 3277], 'As': [2415, 3796], 'expected,': [2416], '(−': [2420, 2455, 2612, 2653, 2715], '+/−)': [2421, 2466, 2613, 2639], '+/+),': [2424], 'phase': [2431, 2437, 3324, 3333], '(yellow': [2432], 'curve)': [2433], '(red': [2438], 'curve),': [2439], 'transition': [2452, 2462, 3246, 4890], '(blue': [2453], 'curve:': [2454, 2464], '+/+)': [2456, 2626, 2654, 2716], 'FFL)': [2457], '(green': [2463], 'FFL).': [2467], 'ensure': [2470, 2517], 'proper': [2472, 2518], 'G1-specific': [2476], '(S+G2+M)-specific': [2479], 'convert': [2483], 'periodic': [2485, 2678, 3497, 3571, 3681, 3826], 'strict': [2494], 'alternation': [2495], 'S-phase': [2497, 2658, 2709, 2742, 3620, 4449], 'entry': [2498, 3621], 'M-phase': [2500, 3623], 'exit,': [2501], 'transitions': [2504, 3190, 3757, 4792], 'occur': [2507], 'duplication': [2519], 'separation': [2521], 'genetic': [2525], 'material.': [2526], 'Next,': [2527], 'use': [2529], 'diverse': [2530], 'evidences': [2531], 'predict,': [2533], 'cases,': [2536], 'effects': [2542], 'S6).': [2549], 'predictions,': [2552], 'could': [2554], '59': [2556], '46': [2559], 'which': [2562, 2994, 3186, 3270], 'S7).': [2574, 3458], 'examples': [2577, 2609, 2941, 3450, 3462, 3485], 'including': [2584, 3231], 'regulators': [2587], 'whose': [2588], 'times': [2589], 'match': [2596], 'predictions': [2598], 'theory': [2601, 2698, 3358], '2B).': [2603], '3,': [2606], 'controlling': [2615, 2628, 2641, 2656], 'protein,': [2618, 2631, 2645], 'Sic1': [2619, 3085, 3102, 3173, 3198, 3212, 4335], '(Knapp': [2620, 2924], '1996),': [2623], 'mitotic': [2630, 2789, 2811, 3138, 3308, 3582, 4442, 5215], 'Cdc5': [2632, 3218, 3257], '(Zhu': [2633], '2000),': [2636], 'Dbf2': [2646, 2814, 2824, 2831, 2855], '(Visintin': [2647], '2001)': [2650], 'initiator,': [2659, 2710], 'Sld2': [2660, 2706, 2740, 2864, 2975, 2987, 2998, 4766, 5046, 5237], '(Tanaka': [2661, 2744, 2871], '2007a).': [2664], 'Sld2,': [2669, 2887], 'database': [2671, 3791, 3846], 'search': [2672], 'revealed': [2673, 3430], "Cdk'": [2675, 3347], '(with': [2677], 'expression).': [2680], 'However,': [2681, 3278], 'Ash1': [2682, 2718, 2888, 2904], '(Teixeira': [2686, 2896, 3792], '2006)': [2689], 'Sld2.': [2695, 2908], 'should': [2713], 'predicted': [2720, 2777], 'activator': [2724, 2796], 'SLD2': [2726, 2894], 'prediction': [2729], 'fits': [2730], 'recent': [2731], 'role': [2736, 3306, 3653, 5011], '2007b;': [2747, 2874], 'Zegerman': [2748, 2875, 5230], 'Diffley,': [2750, 3005], 'fluctuation': [2756], 'profile': [2757], '(not': [2758], 'shown)': [2759], '(Masumoto': [2760], '3.Examples': [2765], 'transcriptional': [2769, 2795, 4557], 'post-translational': [2771, 4559], 'controls.': [2772], 'Interaction': [2773], '(±)': [2775], 'rules': [2780], 'presented': [2781], 'S6.': [2785], 'Both': [2787], 'polo': [2790], '(Cdc5)': [2792], '(Fkh2)': [2797, 2820], 'presumably': [2801], '(bound': [2805], 'B-type': [2807, 4338, 4880], 'cyclins).': [2808], 'initiator': [2813], 'shares': [2815], 'Cdc5,': [2822], 'appears': [2825], 'inhibited': [2828, 2915], 'PEST': [2834, 2989, 4811], 'sequence': [2835, 3504, 3589], '(Rechsteiner': [2836], 'Rogers,': [2838], '1996)': [2839], 'phosphoprotein': [2842], 'detected': [2845], '(Chi': [2846], '2007),': [2849, 3177], 'suggesting': [2850], 'induces': [2856, 3021, 3924], 'degradation.': [2858], '(C)': [2859], 'inducer': [2863], '2007).': [2878], 'Although': [2879], 'there': [2880, 3534], 'no': [2882, 4062], 'documented': [2883], 'Our': [2900, 3428, 3594], 'predicts': [2902], '(D)': [2909], 'stabilizer,': [2912], 'Sic1,': [2913], 'directly': [2918, 3900], 'Swi5': [2923, 4610], '1996).': [2927, 3593], '(E)': [2928], 'An': [2929], 'example': [2930, 3090, 3224], 'complex': [2933, 3082, 3520, 3725, 3807, 4420], 'embedding': [2934, 3145], 'Further': [2937], 'details': [2938, 3856], 'S7.': [2945], 'basic': [2952, 3490, 3608], 'described': [2957], 'theoretically': [2958], 'clearly': [2960], 'oversimplifications': [2961], 'schemes': [2965], 'operating': [2966], 'real': [2968], 'cells.': [2969, 4378], '3C)': [2977], 'illustrates': [2978], 'overlapping': [2983, 3030], 'even': [2985, 3701], 'contradictory.': [2986], 'contains': [2988], 'sequences': [2990, 4812], 'S6),': [2993], 'that,': [2996], '(Zegerman': [3003], '2007b),': [3010], 'site': [3019], 'degradation,': [3023, 3925], 'giving': [3024], 'overlapping,': [3026], 'contradictory': [3027], 'Similar': [3029], 'initiators': [3036, 3466], 'replication,': [3039, 3419], 'MCM': [3042], 'Cdc6.': [3045], '(Our': [3046], 'methods': [3047, 3763], 'insufficient': [3050], 'early,': [3054], 'before': [3062], 'degraded.)': [3065], 'Cln3': [3069], '3E)': [3071], 'interlocked': [3074, 3266], 'employed': [3078], 'achieve': [3080, 3395], 'effects.': [3084], '3D)': [3087], 'presents': [3088, 3221], 'composed': [3095], 'double-negative': [3098, 3117, 3147], 'loop,': [3100], 'because': [3101, 3225], 'well-known': [3105], 'inhibitor': [3106, 3202, 4336, 4617, 4883], 'Cdk1-Clb': [3108], '(Schwob': [3112], '1994).': [3115], '(=positive)': [3118], 'switch,': [3124], 'flipping': [3125], '(Cdk1-Clb': [3127, 3134], 'high)': [3129], 'start': [3131], 'off': [3133], 'low)': [3136, 3329], '(Chen': [3140], '2004).': [3143, 3252], 'switch': [3155], 'made': [3157, 3187], 'robust.': [3159, 3192], 'feature': [3161], 'demonstrated': [3164], 'recently': [3165], 'removing': [3167, 3180], 'sites': [3171, 4302], '(Cross': [3174], 'i.e.': [3178], 'leg': [3182], 'passing,': [3194], 'note': [3196], 'Cdk1-Cln,': [3204], 'Cln-dependent': [3207], 'do': [3209, 3300], 'simple': [3215], '3A)': [3220], 'multiple': [3228], 'downstream': [3229, 3416], 'targets,': [3230], 'Cdc25,': [3235], 'Wee1': [3236, 3299], 'cyclin': [3238, 4443, 4615, 4881], 'activating': [3242], '(Barr': [3249], 'Activation': [3253], 'turns': [3258], 'pair': [3264], 'stabilizing': [3275], 'operational': [3288], 'homologues': [3295], 'Cdc25': [3297], 'entry.': [3309, 4919], 'continually': [3319], 'either': [3321], '(when': [3325, 3334], 'high).': [3338], 'Consulting': [3339], '1A,': [3341], "'chain'": [3349], 'serve': [3352], 'purposes': [3354], 'equally': [3355], 'well.': [3356], 'But': [3357], 'robust': [3365], 'single-arm': [3370], '2003).': [3375], 'robustness': [3382], 'advantage:': [3387], 'needed': [3393], 'induce': [3415], 'events': [3417, 3444, 3506, 3579, 3662], '(DNA': [3418], 'division)': [3423], 'order.': [3427], 'analysis': [3429, 3765, 4157, 4262, 5089], 'playing': [3440], '1B)': [3446], 'predict': [3452], 'inducers': [3470], 'under': [3473], '3B': [3480], 'C).': [3482], 'Altogether,': [3483], 'suggest': [3486], 'converting': [3496, 3655], 'oscillations': [3499], 'topologies.': [3522], 'Conclusion': [3523], 'organisms': [3527], 'studied': [3531], 'detail,': [3533], 'appear': [3535], 'Cdk–cyclin': [3541, 3572, 3603, 3644], 'pairs': [3542], 'crucial': [3545, 3652], 'coordinating': [3548], 'Each': [3552], 'own': [3557], 'suite': [3558], 'probably': [3561], 'Nonetheless,': [3565, 3736], 'sufficient': [3575], 'viable': [3587], '(Fisher': [3590], 'Nurse,': [3592], 'simulation': [3595], '2B)': [3597], 'shows,': [3598], 'principle,': [3600], 'pair,': [3604], 'utilizing': [3605], 'four': [3607], 'motifs,': [3610], 'G1-': [3613], 'G2-specific': [3615], 'trigger': [3619], 'alternating': [3627], 'manner.': [3628], 'imagine': [3630], 'last': [3633], 'ancestor': [3635], 'present-day': [3637], 'relied': [3640], 'signal,': [3646], 'played': [3650], 'oscillatory': [3658], 'coordinated': [3661], 'eukaryotic-style': [3665], 'idealized': [3672], 'view': [3673], '1)': [3675], 'provides': [3684], 'scenario': [3687], 'evolution': [3690], 'eukaryotes': [3697], 'merit': [3700], 'now': [3702], "'first": [3705], "approximation'": [3706], 'organization': [3710, 5166], 'present': [3716], 'day': [3717], 'organisms,': [3718], 'exploit': [3729], 'modify': [3731], 'intrinsic': [3733], 'dynamical': [3734], 'potentials.': [3735], 'still': [3740], 'intimately': [3741], 'yeast.': [3760, 4269, 4774, 5054, 5248], 'Materials': [3761], 'obtained': [3769], '2005).': [3781, 3850], 'downloaded': [3787, 3842], 'YEASTRACT': [3790, 5083], 'act': [3799], 'complexes,': [3801], 'say': [3803], 'if': [3812], 'total,': [3824], '600': [3825], 'de': [3831, 4409, 4547], 'Lichtenberg': [3832, 4410, 4548], 'al': [3834, 4668], '(2005).': [3835], 'FunCat': [3837], 'CYGD': [3845], '(Guldener': [3847], 'information,': [3854], 'determining': [3860], 'TF–EP': [3864], 'connections': [3865], 'Cdk1-mediated': [3871], 'phosphorylations.': [3873], 'Model': [3874], 'construction': [3875], 'wrote': [3877], 'S4)': [3882], 'rates': [3885], 'change': [3887], 'forms': [3893], 'only.': [3912], 'assume': [3921], 'thus': [3926], 'degraded,': [3931], 'total': [3936, 3944], 'amount': [3937], 'represents': [3942], 'form.': [3946], 'Parameters': [3947], 'chosen': [3949], 'get': [3951], 'unique': [3952], 'course': [3965], 'was': [3966, 4005], 'minimal': [3970], 'system,': [3976], 'comparable': [3977], 'Acknowledgements': [3983], 'thank': [3985], 'Fredrick': [3986], 'R': [3987, 4399], 'Cross': [3988, 4254, 4325, 4907], 'stimulating': [3990], 'discussions': [3991], 'Orkun': [3993], 'S': [3994, 4046, 4889], 'Soyer': [3995, 4388], 'critical': [3998], 'reading': [3999], 'paper.': [4002], 'supported': [4006], 'grants': [4008], 'Hungarian': [4010], 'Scientific': [4011], 'Fund': [4013], '(OTKA-F60414),': [4014], 'Italian': [4015], 'Ministry': [4016], 'Project': [4021], 'FIRB': [4022], '(RBPR0523C3)': [4023], '(AC-N),': [4024], 'Council': [4027], '(202591)': [4028], '(CP),': [4029], 'Commission': [4032], '(YSBN': [4033], 'FP7:': [4035], '201142),': [4036], 'National': [4038], 'Institutes': [4039], 'Health': [4041], '(5R01GM079207)': [4042], 'James': [4045], 'McDonnell': [4047], '(21002050)': [4049], '(BN': [4050], 'JJT).': [4052], 'Conflict': [4053], 'Interest': [4055], 'authors': [4057], 'declare': [4058], 'conflict': [4063], 'interest.': [4065], 'Supporting': [4066], 'S1': [4070, 4094], '(application/jpg,': [4071, 4077, 4083, 4089], '642.4': [4072], 'KB)': [4073, 4097, 4103, 4109, 4115, 4122, 4128, 4134, 4139], 'S2': [4076, 4100], '2.8': [4078], 'MB)': [4079, 4085, 4091], 'S3': [4082, 4106], '2.2': [4084], 'S4': [4088, 4112], '2.4': [4090], '(application/xls,': [4095, 4101, 4107, 4113, 4126, 4132], '369': [4096], '60': [4102], '105.5': [4108], '1,009': [4114], 'S5': [4118], '(PDF': [4119], 'document,': [4120], '14.7': [4121], 'S6': [4125], '61.5': [4127], 'S7': [4131], '40': [4133], '(application/doc,': [4137], '90': [4138], 'References': [4140], 'Adelman': [4141], 'K,': [4142, 4832, 4935, 4976, 5035, 5189], 'La': [4143], 'Porta': [4144], 'A,': [4145, 4253, 4279, 4359, 4387, 4491, 4571, 4729, 4826, 4828], 'Santangelo': [4146], 'TJ,': [4147], 'Lis': [4148], 'JT,': [4149], 'Roberts': [4150], 'JW,': [4151], 'Wang': [4152], 'MD': [4153], '(2002)': [4154, 4669, 4762], 'Single': [4155], 'molecule': [4156], 'RNA': [4159], 'polymerase': [4160], 'elongation': [4161], 'reveals': [4162], 'uniform': [4163], 'kinetic': [4164], 'behavior.': [4165], 'Proc': [4166, 4315, 4716], 'Natl': [4167, 4316, 4717], 'Acad': [4168, 4317, 4718], 'Sci': [4169, 4318, 4719, 4819], '99:': [4171], '13538–13543CrossrefCASPubMedWeb': [4172], 'Science®Google': [4174, 4195, 4220, 4246, 4276, 4323, 4356, 4384, 4407, 4431, 4465, 4522, 4541, 4566, 4596, 4625, 4680, 4700, 4724, 4752, 4779, 4804, 4823, 4868, 4898, 4924, 4965, 5001, 5028, 5059, 5103, 5133, 5158, 5176, 5205, 5228, 5253, 5285], 'Scholar': [4175, 4196, 4221, 4247, 4277, 4324, 4357, 4385, 4408, 4432, 4466, 4523, 4542, 4567, 4597, 4626, 4681, 4701, 4725, 4753, 4780, 4805, 4824, 4869, 4899, 4925, 4966, 5002, 5029, 5060, 5104, 5134, 5159, 5177, 5206, 5229, 5254, 5286], 'Bardin': [4176], 'AJ,': [4177], 'Amon': [4178, 5209], '(2001)': [4180, 5139, 5211], 'MEN': [4181], 'SIN:': [4183], "what's": [4184], 'difference?': [4186], 'Nat': [4187, 4212, 4798], 'Rev': [4188, 4213], 'Mol': [4189, 4214, 4270, 4588, 4619, 4747, 4959, 5222], 'Biol': [4191, 4216, 4242, 4271, 4590, 4621, 4748, 4800, 4960, 5129, 5154, 5172, 5223], '2:': [4192, 5025], '815–826CrossrefCASPubMedWeb': [4193], 'Barr': [4197], 'FA,': [4198], 'Sillje': [4199], 'HH,': [4200], 'Nigg': [4201], 'EA': [4202], '(2004)': [4203, 4260, 4847], 'Polo-like': [4204], 'orchestration': [4208], '5:': [4217], '429–440CrossrefCASPubMedWeb': [4218], 'Blow': [4222], 'JJ': [4223, 4259], '(1993)': [4224], 'Preventing': [4225], 're-replication': [4226], 'cycle:': [4233, 5145], 'evidence': [4234], 'licensing': [4238], 'factor.': [4239], '122:': [4243], '993–1002CrossrefCASPubMedWeb': [4244], 'Chen': [4248, 5107], 'KC,': [4249, 5108], 'Calzone': [4250], 'L,': [4251, 4328, 4601], 'FR,': [4255, 4326], 'Novak': [4256, 4366, 4781, 5109, 5137, 5162], 'B,': [4257, 4363, 4495, 4497, 4656, 4782, 4786], '15:': [4273, 4460, 5130], '3841–3862CrossrefCASPubMedWeb': [4274], 'Chi': [4278], 'Huttenhower': [4280], 'C,': [4281, 4479, 4506], 'Geer': [4282], 'LY,': [4283], 'Coon': [4284], 'JJ,': [4285, 4365, 4658, 4784, 5106, 5136, 5161], 'Syka': [4286], 'JE,': [4287, 4487], 'Bai': [4288], 'DL,': [4289, 4434], 'Shabanowitz': [4290], 'J,': [4291, 4477, 4481, 4485, 4502, 4648, 4834], 'Burke': [4292], 'DJ,': [4293, 4603], 'Troyanskaya': [4294], 'OG,': [4295], 'Hunt': [4296], 'DF': [4297], '(2007)': [4298, 4331, 4368, 4789, 5234], 'Analysis': [4299], 'Saccharomyces': [4306, 4341, 4674, 4954, 5095], 'cerevisiae': [4307, 4342, 4955], 'electron': [4309], 'transfer': [4310], 'dissociation': [4311], '(ETD)': [4312], 'mass': [4313], 'spectrometry.': [4314], '104:': [4320], '2193–2198CrossrefCASPubMedWeb': [4321], 'Schroeder': [4327], 'Bean': [4329], 'JM': [4330], 'Phosphorylation': [4332, 5235], 'cyclins': [4339, 4914], 'essential': [4345, 4767, 4984], 'contributes': [4347], 'robustness.': [4351], 'Genetics': [4352], '176:': [4353], '1541–1555CrossrefCASPubMedWeb': [4354], 'O,': [4361], 'Gyorffy': [4362, 4785], 'Modeling': [4369], '(SIN)': [4374], 'Curr': [4379, 5126, 5171], 'Genet': [4380], '51:': [4381], '245–255CrossrefCASPubMedWeb': [4382], 'OS': [4389], '(2008)': [4390, 4530, 4576, 4909, 5164], 'Adaptive': [4391], 'two-state': [4396], 'protein.': [4397], 'Soc': [4400], 'Interface': [4401], '5': [4402], '(Suppl': [4403], '1):': [4404], 'S41–S47CrossrefCASPubMedWeb': [4405], 'U,': [4411, 4468, 4549, 4840], 'LJ,': [4413, 4525, 4544], 'Brunak': [4414, 4550], 'Bork': [4416, 4552], 'P': [4417, 4436, 4553], '(2005)': [4418, 4509, 4686], 'Dynamic': [4419], 'formation': [4421], 'Science': [4427, 4676], '307:': [4428], '724–727CrossrefCASPubMedWeb': [4429], 'Fisher': [4433], 'Nurse': [4435], '(1996)': [4437, 4606, 4810], 'p34cdc2': [4445], 'promotes': [4447, 5243], 'absence': [4454], 'cyclins.': [4457], 'EMBO': [4458], '850–860Wiley': [4461], 'Online': [4462, 4593], 'LibraryCASPubMedWeb': [4463], 'Munsterkotter': [4469, 4843], 'M,': [4470, 4683, 4807, 4836, 4844, 5074, 5185], 'Kastenmuller': [4471], 'G,': [4472, 4842, 4929, 5256], 'Strack': [4473], 'N,': [4474, 4974], 'van': [4475], 'Helden': [4476], 'Lemer': [4478], 'Richelles': [4480], 'Wodak': [4482], 'SJ,': [4483], 'Garcia-Martinez': [4484], 'Perez-Ortin': [4486], 'Michael': [4488], 'H,': [4489, 4755], 'Kaps': [4490], 'Talla': [4492], 'E,': [4493, 4504, 4573, 4664, 4871], 'Dujon': [4494], 'Andre': [4496], 'Souciet': [4498], 'JL,': [4499], 'De': [4500], 'Montigny': [4501], 'Bon': [4503], 'Gaillardin': [4505], 'Mewes': [4507, 4845], 'HW': [4508, 4846], 'CYGD:': [4510], 'Comprehensive': [4512, 4945], 'Yeast': [4513], 'Genome': [4514], 'Database.': [4515], 'Nucleic': [4516, 4862, 5097], 'Acids': [4517, 4863, 5098], 'Res': [4518, 4864, 5099], '33:': [4519], 'D364–D368CrossrefCASPubMedWeb': [4520], 'Krutchinsky': [4526], 'AN,': [4527], 'Morgan': [4528, 4684, 5192], 'DO': [4529, 4685, 5193], 'Positive': [4531, 4910], 'sharpens': [4533], 'anaphase': [4535], 'switch.': [4536], 'Nature': [4537, 4562, 4696, 4775, 4920, 5055, 5201, 5249, 5281], '454:': [4538, 4921], '353–357CrossrefCASPubMedWeb': [4539], 'TS,': [4546], '(2006)': [4554, 5081], 'Co-evolution': [4555], 'cell-cycle': [4560, 4791], 'regulation.': [4561], '443:': [4563], '594–597CrossrefCASPubMedWeb': [4564], 'Bren': [4570], 'Dekel': [4572], 'Alon': [4574, 4704, 4730], 'U': [4575, 4705, 4731], 'generate': [4582], 'non-monotonic': [4583], 'input': [4584], 'Syst': [4589], '4:': [4591], '203Wiley': [4592], 'LibraryPubMedWeb': [4594], 'Knapp': [4598], 'D,': [4599, 4830, 4941, 5264], 'Bhoite': [4600], 'Stillman': [4602], 'Nasmyth': [4604, 4876], 'K': [4605, 4877], 'regulates': [4611], 'p40Sic1.': [4618], '16:': [4622], '5701–5707CrossrefCASPubMedWeb': [4623], 'Lee': [4627], 'TI,': [4628], 'Rinaldi': [4629], 'NJ,': [4630], 'Robert': [4631], 'F,': [4632], 'Odom': [4633], 'DT,': [4634], 'Bar-Joseph': [4635], 'Z,': [4636], 'Gerber': [4637], 'GK,': [4638], 'Hannett': [4639], 'NM,': [4640], 'Harbison': [4641], 'CT,': [4642], 'Thompson': [4643], 'CM,': [4644], 'Simon': [4645], 'I,': [4646, 4838], 'Zeitlinger': [4647], 'Jennings': [4649], 'EG,': [4650], 'Murray': [4651], 'HL,': [4652], 'Gordon': [4653], 'DB,': [4654], 'Ren': [4655], 'Wyrick': [4657], 'Tagne': [4659], 'JB,': [4660], 'Volkert': [4661], 'TL,': [4662], 'Fraenkel': [4663], 'Gifford': [4665], 'DK': [4666], 'Transcriptional': [4670], 'networks': [4672], 'cerevisiae.': [4675, 4893, 5096], '298:': [4677], '799–804CrossrefCASPubMedWeb': [4678], 'Cyclin': [4687], 'specificity': [4688], 'cyclin-dependent': [4693, 5198, 5241], 'substrates.': [4695], '434:': [4697], '104–108CrossrefCASPubMedWeb': [4698], 'Mangan': [4702, 4726], '(2003)': [4706, 4732, 5111, 5194], 'Structure': [4707], '100:': [4721], '11980–11985CrossrefCASPubMedWeb': [4722], 'Zaslaver': [4728], 'feedforward': [4735], 'serves': [4737], 'sign-sensitive': [4740], 'element': [4742], 'networks.': [4745], '334:': [4749], '197–204CrossrefCASPubMedWeb': [4750], 'Masumoto': [4754], 'Muramatsu': [4756, 5036], 'Kamimura': [4758, 5038], 'Y,': [4759, 5039], 'Araki': [4760, 5007, 5040], 'H': [4761, 5008, 5041], 'S-Cdk-dependent': [4763], 'chromosomal': [4769], '415:': [4776], '651–655CrossrefCASPubMedWeb': [4777], 'Irreversible': [4790], 'due': [4794], 'systems-level': [4796], 'feedback.': [4797], '9:': [4801, 4962], '724–728CrossrefCASPubMedWeb': [4802], 'Rechsteiner': [4806], 'Rogers': [4808], 'SW': [4809], 'proteolysis.': [4816], 'Trends': [4817], 'Biochem': [4818], '21:': [4820], '267–271CrossrefCASPubMedWeb': [4821], 'Ruepp': [4825], 'Zollner': [4827], 'Maier': [4829], 'Albermann': [4831], 'Hani': [4833], 'Mokrejs': [4835], 'Tetko': [4837], 'Mannhaupt': [4841], 'FunCat,': [4849], 'annotation': [4852], 'scheme': [4853], 'systematic': [4855], 'classification': [4856], 'whole': [4860], 'genomes.': [4861], '32:': [4865], '5539–5545CrossrefCASPubMedWeb': [4866], 'Schwob': [4870], 'Bohm': [4872], 'T,': [4873, 4968, 4970, 4972, 5033, 5260], 'Mendenhall': [4874], 'MD,': [4875], '(1994)': [4878], 'p40sic1': [4884], 'S.': [4892], '79:': [4895], '233–244CrossrefCASPubMedWeb': [4896], 'JM,': [4901], 'Di': [4902], 'Talia': [4903], 'Siggia': [4905], 'ED,': [4906], 'FR': [4908], 'ensures': [4915], '291–296CrossrefCASPubMedWeb': [4922], 'Spellman': [4926, 5257], 'PT,': [4927, 5258], 'Sherlock': [4928], 'Zhang': [4930], 'MQ,': [4931], 'Iyer': [4932], 'VR,': [4933], 'Anders': [4934], 'Eisen': [4936], 'MB,': [4937], 'Brown': [4938, 5261], 'PO,': [4939, 5262], 'Botstein': [4940, 5263], 'Futcher': [4942, 5267], '(1998)': [4944], 'identification': [4946], 'microarray': [4957], 'hybridization.': [4958], '3273–3297CrossrefCASPubMedWeb': [4963], 'Sutani': [4967], 'Yuasa': [4969], 'Tomonaga': [4971], 'Dohmae': [4973], 'Takio': [4975], 'Yanagida': [4977], '(1999)': [4979], 'Fission': [4980], 'condensin': [4982], 'complex:': [4983], 'non-SMC': [4987], 'subunits': [4988], 'condensation': [4990], 'Cdc2': [4992], 'Cut3/SMC4.': [4995], 'Genes': [4996], 'Dev': [4997], '13:': [4998], '2271–2283CrossrefCASPubMedWeb': [4999], 'Tak': [5005], 'YS,': [5006], '(2007a)': [5009], 'CDK': [5013], 'step': [5017], 'eukaryotes.': [5022], 'Div': [5024], '16CrossrefCASPubMedWeb': [5026], 'Umemori': [5032], 'Hirai': [5034], '(2007b)': [5042], 'CDK-dependent': [5043], 'Sld3': [5048, 5239], 'initiates': [5049], '445:': [5056, 5250], '328–332CrossrefCASPubMedWeb': [5057], 'Teixeira': [5061], 'MC,': [5062], 'Monteiro': [5063], 'P,': [5064, 5066, 5231], 'Jain': [5065], 'Tenreiro': [5067], 'Fernandes': [5069], 'AR,': [5070], 'Mira': [5071], 'NP,': [5072], 'Alenquer': [5073], 'Freitas': [5075], 'AT,': [5076], 'Oliveira': [5077], 'AL,': [5078], 'Sa-Correia': [5079], 'I': [5080], 'database:': [5084], 'tool': [5086], 'associations': [5093], '34:': [5100], 'D446–D451CrossrefCASPubMedWeb': [5101], 'Sniffers,': [5112], 'buzzers,': [5113], 'toggles,': [5114], 'blinkers:': [5116], 'signaling': [5121], 'cell.': [5125], 'Opin': [5127], '221–231CrossrefCASPubMedWeb': [5131], 'Regulation': [5140, 5212], 'molecular': [5146], 'antagonism,': [5147], 'hysteresis': [5148], 'irreversible': [5150], 'transitions.': [5151], 'Theor': [5153], '210:': [5155], '249–263CrossrefCASPubMedWeb': [5156], 'Temporal': [5165], '18:': [5173], 'R759–R768CrossrefCASPubMedWeb': [5174], 'Ubersax': [5178], 'JA,': [5179], 'Woodbury': [5180], 'EL,': [5181], 'Quang': [5182], 'PN,': [5183], 'Paraz': [5184], 'Blethrow': [5186], 'JD,': [5187], 'Shah': [5188], 'Shokat': [5190], 'KM,': [5191], 'Targets': [5195], '425:': [5202], '859–864CrossrefCASPubMedWeb': [5203], 'Visintin': [5207], 'R,': [5208], 'Cdc15': [5219], 'Dbf2.': [5221], '12:': [5225], '2961–2974CrossrefCASPubMedWeb': [5226], 'Diffley': [5232], 'JF': [5233], '281–285CrossrefCASPubMedWeb': [5251], 'Zhu': [5255], 'Volpe': [5259], 'Davis': [5265], 'TN,': [5266], '(2000)': [5269], 'Two': [5270], 'forkhead': [5272], 'pseudohyphal': [5279], 'growth.': [5280], '406:': [5282], '90–94CrossrefCASPubMedWeb': [5283], 'Previous': [5287], 'ArticleNext': [5288], 'Article': [5289], 'Volume': [5290], '5Issue': [5291], '11': [5292], '2009In': [5294], 'issue': [5296], 'FiguresReferencesRelatedDetailsLoading': [5297], '...': [5298]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2006777346', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 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