Title: Cobalt(II)-Catalyzed Intermolecular Benzylic C−H Amination with 2,2,2-Trichloroethoxycarbonyl Azide (TrocN<sub>3</sub>)
Abstract: 2,2,2-Trichloroethoxycarbonyl azide (TrocN3) is an effective nitrene source for cobalt(II)-catalyzed intermolecular nitrene insertion of C−H bonds. Among different metalloporphyrins studied, Co(II)(TPP) was shown to be a competent catalyst for the selective amination of various benzylic C−H bonds under mild conditions without the need of other reagents or additives, forming the desired Troc-protected amines in moderate to high yields with nitrogen gas as the only byproduct.
Publication Year: 2009
Publication Date: 2009-12-22
Language: en
Type: article
Indexed In: ['crossref']
Access and Citation
Cited By Count: 178
AI Researcher Chatbot
Get quick answers to your questions about the article from our AI researcher chatbot