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'inhibited': [38, 71, 222, 246], 'basal': [39, 247], 'ligand-stimulated': [41], 'phosphorylation': [43, 170], 'without': [44, 225], 'a': [45, 112, 150, 217], 'decrease': [46], 'in': [47, 77, 98, 111, 146, 158, 201, 255, 275], 'content,': [49], 'EGF-binding': [50], 'sites,': [51], 'or': [52, 229], 'binding': [53], 'affinity.': [54], 'Incubation': [55], '0.1-1': [60], 'AG-1517': [62, 69], 'abrogated': [63, 205], '(125)I-EGF': [64], 'internalization.': [65], 'Both': [66], 'markedly': [70], 'colony': [75], 'formation': [76, 97], 'soft': [78], 'agarose': [79], 'at': [80, 91], 'concentrations': [81], '0.01': [83], '1': [85], 'microM.': [86], 'Daily': [87], 'injections': [88], '50': [92], 'mg/kg': [93], 'delayed': [94], 'athymic': [99], 'nude': [100], 'mice.': [101], 'A': [102], 'transient': [103], 'exposure': [104], 'resulted': [110], 'dose-dependent': [113], 'up-regulation': [114, 284], 'cyclin-dependent': [117], 'inhibitor': [119, 219, 241], 'p27,': [120, 251], 'down-regulation': [121], 'cyclin': [123, 175], 'D1': [124, 176], 'active': [127, 305], 'MAPK,': [128, 298], 'hypophosphorylation': [130], 'retinoblastoma': [133], 'protein': [134, 177, 191, 200], '(Rb).': [135], 'These': [136, 257], 'changes': [137], 'were': [138, 178, 193], 'temporally': [139], 'associated': [140], 'recruitment': [142], 'phase': [148, 188], 'marked': [151], 'reduction': [152], 'proportion': [155], 'phase.': [160], 'Upon': [161], 'removal': [162], 'inhibitor,': [166], 'Rb': [169], 'levels': [173, 192, 232], 'quickly': [179], 'restored,': [180], 'but': [181, 299], 'did': [184], 'not': [185, 292], 'reenter': [186], 'until': [189], 'p27': [190, 196, 199, 261, 286], 'decreased.': [194], 'Phosphorothioate': [195], 'oligonucleotides': [197], 'decreased': [198], 'quinazoline-mediated': [207], 'arrest.': [209], 'PD': [215], '098509,': [216], 'synthetic': [218], 'MEK1,': [221], 'MAPK': [223], 'activity': [224], 'inducing': [226], 'arrest': [228, 267, 282], 'increasing': [230], 'p27.': [234], 'However,': [235], 'treatment': [236], 'LY': [238], '294002,': [239], 'an': [240], 'phosphatidylinositol': [243], '3-kinase': [244], '(PI3K),': [245], 'Akt': [248], 'activity,': [249], 'up-regulated': [250], 'recruited': [253], 'G(1).': [256], 'data': [258], 'suggest': [259], 'that': [260, 268], 'is': [262], 'required': [263], 'for': [264], 'follows': [269], 'interruption': [270, 296, 302], 'receptor-overexpressing': [276], 'cells.': [277], 'In': [278], 'addition,': [279], 'resulting': [287], 'from': [288], 'blockade': [290], 'are': [291], 'due': [293], 'constitutively': [304], 'PI3K': [306], 'function.': [307]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2005075550', 'counts_by_year': [{'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 5}, {'year': 2016, 'cited_by_count': 4}, {'year': 2015, 'cited_by_count': 5}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 8}], 'updated_date': '2024-12-27T11:38:20.525327', 'created_date': '2016-06-24'}