Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2004986663', 'doi': 'https://doi.org/10.1128/jb.185.16.5019-5022.2003', 'title': 'The<i>pst</i>Operon of<i>Bacillus subtilis</i>Is Specifically Induced by Alkali Stress', 'display_name': 'The<i>pst</i>Operon of<i>Bacillus subtilis</i>Is Specifically Induced by Alkali Stress', 'publication_year': 2003, 'publication_date': '2003-08-01', 'ids': {'openalex': 'https://openalex.org/W2004986663', 'doi': 'https://doi.org/10.1128/jb.185.16.5019-5022.2003', 'mag': '2004986663', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/12897025', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/166449'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/jb.185.16.5019-5022.2003', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S133274750', 'display_name': 'Journal of Bacteriology', 'issn_l': '0021-9193', 'issn': ['0021-9193', '1067-8832', '1098-5530'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://doi.org/10.1128/jb.185.16.5019-5022.2003', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5019089108', 'display_name': 'Akram Atalla', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I54009628', 'display_name': 'University of Bayreuth', 'ror': 'https://ror.org/0234wmv40', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I54009628']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Akram Atalla', 'raw_affiliation_strings': ['Institute of Genetics, University of Bayreuth, D-95440 Bayreuth, Germany'], 'affiliations': [{'raw_affiliation_string': 'Institute of Genetics, University of Bayreuth, D-95440 Bayreuth, Germany', 'institution_ids': ['https://openalex.org/I54009628']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5008389029', 'display_name': 'Wolfgang Schumann', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I54009628', 'display_name': 'University of Bayreuth', 'ror': 'https://ror.org/0234wmv40', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I54009628']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Wolfgang Schumann', 'raw_affiliation_strings': ['Institute of Genetics, University of Bayreuth, D-95440 Bayreuth, Germany'], 'affiliations': [{'raw_affiliation_string': 'Institute of Genetics, University of Bayreuth, D-95440 Bayreuth, Germany', 'institution_ids': ['https://openalex.org/I54009628']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.851, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 28, 'citation_normalized_percentile': {'value': 0.797293, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 88, 'max': 89}, 'biblio': {'volume': '185', 'issue': '16', 'first_page': '5019', 'last_page': '5022'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10120', 'display_name': 'Bacterial Genetics and Biotechnology', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10120', 'display_name': 'Bacterial Genetics and Biotechnology', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11048', 'display_name': 'Bacteriophages and microbial interactions', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2303', 'display_name': 'Ecology'}, 'field': {'id': 'https://openalex.org/fields/23', 'display_name': 'Environmental Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T11455', 'display_name': 'Microbial Inactivation Methods', 'score': 0.9973, 'subfield': {'id': 'https://openalex.org/subfields/1305', 'display_name': 'Biotechnology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/regulon', 'display_name': 'Regulon', 'score': 0.944157}], 'concepts': [{'id': 'https://openalex.org/C203075996', 'wikidata': 'https://www.wikidata.org/wiki/Q139677', 'display_name': 'Operon', 'level': 4, 'score': 0.9740204}, {'id': 'https://openalex.org/C62361671', 'wikidata': 'https://www.wikidata.org/wiki/Q1754612', 'display_name': 'Regulon', 'level': 4, 'score': 0.944157}, {'id': 'https://openalex.org/C2777272437', 'wikidata': 'https://www.wikidata.org/wiki/Q131238', 'display_name': 'Bacillus subtilis', 'level': 3, 'score': 0.83786625}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.703696}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.5209752}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.42918217}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.4116457}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.36741722}, {'id': 'https://openalex.org/C165864922', 'wikidata': 'https://www.wikidata.org/wiki/Q411391', 'display_name': 'Regulation of gene expression', 'level': 3, 'score': 0.3255285}, {'id': 'https://openalex.org/C523546767', 'wikidata': 'https://www.wikidata.org/wiki/Q10876', 'display_name': 'Bacteria', 'level': 2, 'score': 0.22673583}, {'id': 'https://openalex.org/C547475151', 'wikidata': 'https://www.wikidata.org/wiki/Q25419', 'display_name': 'Escherichia coli', 'level': 3, 'score': 0.17359337}], 'mesh': [{'descriptor_ui': 'D001412', 'descriptor_name': 'Bacillus subtilis', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D015964', 'descriptor_name': 'Gene Expression Regulation, Bacterial', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D009876', 'descriptor_name': 'Operon', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D010710', 'descriptor_name': 'Phosphates', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D001412', 'descriptor_name': 'Bacillus subtilis', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D001412', 'descriptor_name': 'Bacillus subtilis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003470', 'descriptor_name': 'Culture Media', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006863', 'descriptor_name': 'Hydrogen-Ion Concentration', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010710', 'descriptor_name': 'Phosphates', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014158', 'descriptor_name': 'Transcription, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/jb.185.16.5019-5022.2003', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S133274750', 'display_name': 'Journal of Bacteriology', 'issn_l': '0021-9193', 'issn': ['0021-9193', '1067-8832', '1098-5530'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc166449', 'pdf_url': 'https://europepmc.org/articles/pmc166449?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC166449', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/12897025', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/jb.185.16.5019-5022.2003', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S133274750', 'display_name': 'Journal of Bacteriology', 'issn_l': '0021-9193', 'issn': ['0021-9193', '1067-8832', '1098-5530'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 15, 'referenced_works': ['https://openalex.org/W1155520140', 'https://openalex.org/W129666705', 'https://openalex.org/W1488051347', 'https://openalex.org/W1527050015', 'https://openalex.org/W1555904090', 'https://openalex.org/W1560706979', 'https://openalex.org/W1569077780', 'https://openalex.org/W1601371949', 'https://openalex.org/W1883026703', 'https://openalex.org/W2012630600', 'https://openalex.org/W2036944766', 'https://openalex.org/W2041431215', 'https://openalex.org/W2107311753', 'https://openalex.org/W2132790938', 'https://openalex.org/W2138081694'], 'related_works': ['https://openalex.org/W4296449001', 'https://openalex.org/W2741414450', 'https://openalex.org/W2416264719', 'https://openalex.org/W2356107242', 'https://openalex.org/W2171972144', 'https://openalex.org/W2132790938', 'https://openalex.org/W2038893582', 'https://openalex.org/W1993278045', 'https://openalex.org/W1930517486', 'https://openalex.org/W1796329565'], 'abstract_inverted_index': {'To': [0], 'cope': [1], 'with': [2], 'a': [3, 96, 128], 'sudden': [4], 'increase': [5], 'in': [6, 127], 'the': [7, 34, 41, 50, 55, 63, 69, 82, 102, 109, 134, 138, 144, 152, 162, 182], 'external': [8], 'pH': [9], 'value': [10], 'to': [11, 54, 61, 79, 116, 158, 177], '8.9,': [12], 'Bacillus': [13], 'subtilis': [14], 'cells': [15], 'induce': [16], 'about': [17], '80': [18], 'genes': [19, 30, 48, 70, 84], 'which': [20], 'can': [21], 'be': [22], 'divided': [23], 'into': [24], 'two': [25, 80], 'classes.': [26], 'Most': [27, 131], 'of': [28, 33, 43, 49, 65, 71, 81, 85, 143, 151, 181], 'these': [29], 'are': [31, 39, 74, 175], 'members': [32], 'sigma(W)': [35], 'regulon,': [36, 154], 'while': [37], 'some': [38], 'under': [40], 'control': [42], 'so-far-unknown': [44], 'transcriptional': [45, 77, 110], 'regulators.': [46], 'The': [47], 'pst': [51, 145, 183], 'operon': [52, 73, 104], 'belong': [53], 'second': [56], 'class.': [57], 'Here,': [58], 'we': [59, 88, 164], 'attempted': [60], 'answer': [62], 'questions': [64], 'why': [66], 'and': [67, 122, 147], 'how': [68], 'this': [72, 86], 'induced.': [75], 'Using': [76], 'fusions': [78], 'five': [83], 'operon,': [87, 146], 'confirmed': [89], 'their': [90], 'induction': [91, 124, 142, 180], 'after': [92, 119], 'alkali': [93, 106, 141, 159, 167, 179], 'stress.': [94, 160], 'Furthermore,': [95], 'Northern': [97], 'blot': [98], 'experiment': [99], 'revealed': [100], 'that': [101, 108, 117, 123, 166], 'complete': [103], 'was': [105, 114, 125], 'inducible,': [107], 'start': [111], 'site': [112], 'used': [113, 118], 'identical': [115], 'phosphate': [120, 135, 171], 'starvation,': [121], 'prevented': [126, 140, 170], 'phoR': [129], 'background.': [130], 'interestingly,': [132], 'increasing': [133], 'concentration': [136], 'within': [137], 'medium': [139], 'phoA,': [148], 'another': [149], 'member': [150], 'PhoRP': [153], 'did': [155], 'not': [156], 'respond': [157], 'In': [161], 'end,': [163], 'showed': [165], 'treatment': [168], 'completely': [169], 'uptake.': [172], 'These': [173], 'results': [174], 'discussed': [176], 'explain': [178], 'operon.': [184]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2004986663', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-14T17:55:44.856083', 'created_date': '2016-06-24'}