Publication Information

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'have': [33, 223], 'appeared': [34], 'early': [36], 'vertebrate': [37], 'ancestors,': [38], 'possibly': [39], 'Gnathostomes.': [40], 'has': [42, 163], 'additional': [43, 249], 'important': [44], 'biochemical': [45], 'properties': [46], 'including': [47], 'inhibition': [48], 'PKA': [50, 86], 'when': [51], 'phosphorylated': [52, 129], 'by': [53, 57, 118], 'Cdk5': [54], 'and': [55, 61, 91, 102, 109, 132, 143, 159, 172, 183, 191, 218, 232], 'regulation': [56, 150], 'casein': [58], 'kinases': [59], '1': [60], '2.': [62], 'highly': [65], 'specific': [68], 'neuronal': [69, 271], 'populations,': [70], 'especially': [71], 'striatal': [72], 'medium-size': [73], 'spiny': [74], 'neurons.': [75, 174], 'As': [76], 'PP1': [77, 139], 'inhibitor': [78], 'amplifies': [80], 'and/or': [81], 'mediates': [82], 'many': [83], 'actions': [84], 'at': [87], 'the': [88, 93, 141, 149, 165, 179, 196, 266, 270], 'plasma': [89], 'membrane': [90], 'cytoplasm,': [94], 'with': [95, 156, 227, 230], 'broad': [97], 'spectrum': [98], 'potential': [100], 'targets': [101], 'functions.': [103], 'also': [105], 'undergoes': [106], 'continuous': [108], 'tightly': [110, 258], 'regulated': [111, 259], 'cytonuclear': [112], 'shuttling.': [113], 'This': [114], 'trafficking': [115], 'controlled': [117], 'phosphorylation': [119], 'Ser-97,': [121, 135], 'which': [122, 263, 274], 'necessary': [124], 'for': [125], 'nuclear': [126], 'export.': [127], 'When': [128], 'on': [130, 134], 'Thr-34': [131], 'dephosphorylated': [133], 'can': [137], 'inhibit': [138], 'nucleus': [142], 'modulate': [144], 'signaling': [145, 250, 260], 'pathways': [146], 'involved': [147], 'chromatin': [152], 'response.': [153], 'Recent': [154], 'work': [155], 'multiple': [157], 'transgenic': [158], 'knockout': [160], 'mutant': [161], 'mice': [162], 'allowed': [164], 'dissection': [166], 'function': [169], 'striato-nigral': [171], 'striato-pallidal': [173], 'implicated': [177], 'action': [180], 'therapeutic': [182], 'abused': [184], 'psychoactive': [185], 'drugs,': [186], 'prefrontal': [188], 'cortex': [189], 'function,': [190], 'sexual': [193], 'behavior.': [194], 'However,': [195], 'contribution': [197], 'human': [201], 'behavior': [202], 'remains': [203], 'poorly': [204], 'understood.': [205], 'Post-mortem': [206], 'studies': [207, 222], 'humans': [209], 'suggest': [210], 'possible': [211, 228], 'alterations': [212], 'levels': [215], 'schizophrenia': [217], 'bipolar': [219], 'disorder.': [220], 'Genetic': [221], 'revealed': [224], 'polymorphism': [226], 'association': [229], 'psychological': [231], 'psychopathological': [233], 'traits.': [234], 'In': [235], 'addition,': [236], 'short': [238], 'isoform': [239], 'DARPP-32,': [241], 't-DARPP,': [242], 'plays': [243], 'role': [245], 'cancer,': [247], 'indicating': [248], 'properties.': [251], 'Thus,': [252], 'non-essential': [256], 'but': [257], 'hub': [261], 'molecule': [262], 'may': [264], 'improve': [265], 'general': [267], 'performance': [268], 'circuits': [272], 'it': [275], 'expressed.': [277]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2004550591', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 5}, {'year': 2022, 'cited_by_count': 12}, {'year': 2021, 'cited_by_count': 7}, {'year': 2020, 'cited_by_count': 12}, {'year': 2019, 'cited_by_count': 5}, {'year': 2018, 'cited_by_count': 7}, {'year': 2017, 'cited_by_count': 10}, {'year': 2016, 'cited_by_count': 7}, {'year': 2015, 'cited_by_count': 7}, {'year': 2014, 'cited_by_count': 7}, {'year': 2013, 'cited_by_count': 17}, {'year': 2012, 'cited_by_count': 9}], 'updated_date': '2025-01-02T13:59:18.124711', 'created_date': '2016-06-24'}