Title: Eosinophilic Syndrome with Methylphenidate Abuse
Abstract: Brief Reports1 August 1978Eosinophilic Syndrome with Methylphenidate AbuseJEFFREY WOLF, M.D., ALAN FEIN, M.D., LOUIS FEHRENBACHER, M.D.JEFFREY WOLF, M.D.Search for more papers by this author, ALAN FEIN, M.D.Search for more papers by this author, LOUIS FEHRENBACHER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-89-2-224 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptRecently we have become aware of a previously unreported syndrome of systemic, pulmonary, and musculoskeletal problems associated with eosinophilia in patients who abuse intravenous methylphenidate (Ritalin®).Sixteen Ritalin-abusing patients were seen between 4 December 1976 and 20 September 1977 at San Francisco General Hospital (Table 1). They came to our attention either through hematologic consultation for marked eosinophilia, through a limited chart review of Ritalin abusers in a drug abuse program, or through a prospective study of all differential counts during a 6-week period. This prospective study identified eosinophil counts greater than 10% in complete blood counts done in all...References1. HAHNSCHWEIDBEATY HAH: Complications of injecting dissolved methylphenidate tablets. Arch Intern Med 123:656-659, 1969 CrossrefMedlineGoogle Scholar2. ROBERTSONREYNOLDSWILSON CRJ: Pulmonary hypertension and foreign body granulomas in intravenous drug abusers. Documentation by cardiac catheterization and lung biopsy. Am J Med 61:657-664, 1976 CrossrefMedlineGoogle Scholar3. Physicians' Desk Reference, 31st ed. Oradell, New Jersey, Medical Economics Co., 1977, p. 735 Google Scholar4. BALDWINPETERS RJ: Hematologic complications from tranquilizers in children. South Med J 61:1072-1075, 1968 CrossrefMedlineGoogle Scholar5. WITTON K: On the use of parenteral methylphenidate. A follow-up report. Am J Psychiatry 121:267-269, 1964 CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: The Cancer Research Institute Cardiovascular Research Institute University of California, San Francisco San Francisco, California PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByAmphétamine et autres psychostimulantsDrug-induced eosinophilic lung diseaseAmphetamine and Other PsychostimulantsMethylphenidate: Increased Abuse or Appropriate Use ?Rheumatic manifestations of diseases associated with substance abuseCase 23-1984Eosinophile LungenkrankheitenClinical Studies of Methylphenidate Serum Levels in Children and Adults 1 August 1978Volume 89, Issue 2Page: 224-225KeywordsBloodChartsComplete blood countDrug abuseEosinophiliaEosinophilsHealth services researchHeartLungsProspective studies Issue Published: 1 August 1978 PDF DownloadLoading ...
Publication Year: 1978
Publication Date: 1978-08-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 13
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