Title: Interaction of liposomes of different phospholipid and ganglioside composition with rat hepatocytes
Abstract: The studies of the effect of phospholipids and gangliosides from different tissues on the interaction between liposomes and rat hepatocytes in the monolayer culture have been carried out. Gangliosides purified from the liver upon their incorporation into liposomal membrane increase the capture of liposomes by these cells in a concentration-dependent manner. The effect of incorporated gangliosides on liposome capture by target cells depends on the phospholipid composition of liposomes. Liposomes with phospholipid-ganglioside composition which most closely resemble that of target cells demonstrate the highest affinity toward these cells.
Publication Year: 1988
Publication Date: 1988-09-01
Language: en
Type: article
Indexed In: ['crossref']
Access and Citation
Cited By Count: 9
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