Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2003433167', 'doi': 'https://doi.org/10.1160/th13-03-0202', 'title': 'Comparison of calibrated dilute thrombin time and aPTT tests with LC-MS/MS for the therapeutic monitoring of patients treated with dabigatran etexilate', 'display_name': 'Comparison of calibrated dilute thrombin time and aPTT tests with LC-MS/MS for the therapeutic monitoring of patients treated with dabigatran etexilate', 'publication_year': 2013, 'publication_date': '2013-01-01', 'ids': {'openalex': 'https://openalex.org/W2003433167', 'doi': 'https://doi.org/10.1160/th13-03-0202', 'mag': '2003433167', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/23783171'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1160/th13-03-0202', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S206235894', 'display_name': 'Thrombosis and Haemostasis', 'issn_l': '0340-6245', 'issn': ['0340-6245', '2567-689X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320000', 'host_organization_name': 'Thieme Medical Publishers (Germany)', 'host_organization_lineage': ['https://openalex.org/P4310320000'], 'host_organization_lineage_names': ['Thieme Medical Publishers (Germany)'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5108152159', 'display_name': 'Jean-Michel Dogné', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I149768937', 'display_name': 'University of Namur', 'ror': 'https://ror.org/03d1maw17', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I149768937']}, {'id': 'https://openalex.org/I4391767857', 'display_name': 'Namur Research Institute for Life Sciences', 'ror': 'https://ror.org/038bmak92', 'country_code': None, 'type': 'facility', 'lineage': ['https://openalex.org/I149768937', 'https://openalex.org/I4391767857']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'Jean-Michel Dogné', 'raw_affiliation_strings': ['Namur Research Institute for Life Sciences'], 'affiliations': [{'raw_affiliation_string': 'Namur Research Institute for Life Sciences', 'institution_ids': ['https://openalex.org/I149768937', 'https://openalex.org/I4391767857']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000944048', 'display_name': 'François Mullier', 'orcid': 'https://orcid.org/0000-0001-6947-6099'}, 'institutions': [{'id': 'https://openalex.org/I149768937', 'display_name': 'University of Namur', 'ror': 'https://ror.org/03d1maw17', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I149768937']}, {'id': 'https://openalex.org/I4391767857', 'display_name': 'Namur Research Institute for Life Sciences', 'ror': 'https://ror.org/038bmak92', 'country_code': None, 'type': 'facility', 'lineage': ['https://openalex.org/I149768937', 'https://openalex.org/I4391767857']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'François Mullier', 'raw_affiliation_strings': ['Namur Research Institute for Life Sciences'], 'affiliations': [{'raw_affiliation_string': 'Namur Research Institute for Life Sciences', 'institution_ids': ['https://openalex.org/I149768937', 'https://openalex.org/I4391767857']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109892826', 'display_name': 'Bernard Châtelain', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Bernard Chatelain', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5105885461', 'display_name': 'Yuko Rönquist-Nii', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I28166907', 'display_name': 'Karolinska Institutet', 'ror': 'https://ror.org/056d84691', 'country_code': 'SE', 'type': 'education', 'lineage': ['https://openalex.org/I28166907']}], 'countries': ['SE'], 'is_corresponding': False, 'raw_author_name': 'Yuko Rönquist-Nii', 'raw_affiliation_strings': ['Karolinska Institutet'], 'affiliations': [{'raw_affiliation_string': 'Karolinska Institutet', 'institution_ids': ['https://openalex.org/I28166907']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5086342867', 'display_name': 'Rickard E. Malmström', 'orcid': 'https://orcid.org/0000-0003-3061-7629'}, 'institutions': [{'id': 'https://openalex.org/I28166907', 'display_name': 'Karolinska Institutet', 'ror': 'https://ror.org/056d84691', 'country_code': 'SE', 'type': 'education', 'lineage': ['https://openalex.org/I28166907']}], 'countries': ['SE'], 'is_corresponding': False, 'raw_author_name': 'Rickard E. Malmström', 'raw_affiliation_strings': ['Karolinska Institutet'], 'affiliations': [{'raw_affiliation_string': 'Karolinska Institutet', 'institution_ids': ['https://openalex.org/I28166907']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068373464', 'display_name': 'Paul Hjemdahl', 'orcid': 'https://orcid.org/0000-0001-5346-275X'}, 'institutions': [{'id': 'https://openalex.org/I28166907', 'display_name': 'Karolinska Institutet', 'ror': 'https://ror.org/056d84691', 'country_code': 'SE', 'type': 'education', 'lineage': ['https://openalex.org/I28166907']}], 'countries': ['SE'], 'is_corresponding': False, 'raw_author_name': 'Paul Hjemdahl', 'raw_affiliation_strings': ['Karolinska Institutet'], 'affiliations': [{'raw_affiliation_string': 'Karolinska Institutet', 'institution_ids': ['https://openalex.org/I28166907']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5078686392', 'display_name': 'Jonathan Douxfils', 'orcid': 'https://orcid.org/0000-0002-7644-5298'}, 'institutions': [{'id': 'https://openalex.org/I149768937', 'display_name': 'University of Namur', 'ror': 'https://ror.org/03d1maw17', 'country_code': 'BE', 'type': 'education', 'lineage': ['https://openalex.org/I149768937']}], 'countries': ['BE'], 'is_corresponding': False, 'raw_author_name': 'Jonathan Douxfils', 'raw_affiliation_strings': ['Douxfils Jonathan, Department of Pharmacy, Namur Thrombosis and Hemostasis Center (NTHC), Namur Research Institute for LIfe Sciences (NARILIS), University of Namur, B-5000, Belgium, E-mail'], 'affiliations': [{'raw_affiliation_string': 'Douxfils Jonathan, Department of Pharmacy, Namur Thrombosis and Hemostasis Center (NTHC), Namur Research Institute for LIfe Sciences (NARILIS), University of Namur, B-5000, Belgium, E-mail', 'institution_ids': ['https://openalex.org/I149768937']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 13.008, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 101, 'citation_normalized_percentile': {'value': 0.942234, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '110', 'issue': '09', 'first_page': '543', 'last_page': '549'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10065', 'display_name': 'Atrial Fibrillation Management and Outcomes', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10065', 'display_name': 'Atrial Fibrillation Management and Outcomes', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11217', 'display_name': 'Cardiac Arrhythmias and Treatments', 'score': 0.9906, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10217', 'display_name': 'Cardiac electrophysiology and arrhythmias', 'score': 0.9653, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/therapeutic-drug-monitoring', 'display_name': 'Therapeutic Drug Monitoring', 'score': 0.5586122}, {'id': 'https://openalex.org/keywords/direct-thrombin-inhibitor', 'display_name': 'Direct thrombin inhibitor', 'score': 0.5046023}, {'id': 'https://openalex.org/keywords/thrombin-time', 'display_name': 'Thrombin time', 'score': 0.42919174}], 'concepts': [{'id': 'https://openalex.org/C2778810321', 'wikidata': 'https://www.wikidata.org/wiki/Q419345', 'display_name': 'Dabigatran', 'level': 4, 'score': 0.93667173}, {'id': 'https://openalex.org/C2780272996', 'wikidata': 'https://www.wikidata.org/wiki/Q1261151', 'display_name': 'Therapeutic drug monitoring', 'level': 3, 'score': 0.5586122}, {'id': 'https://openalex.org/C43617362', 'wikidata': 'https://www.wikidata.org/wiki/Q170050', 'display_name': 'Chromatography', 'level': 1, 'score': 0.54404944}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.5378605}, {'id': 'https://openalex.org/C2776710957', 'wikidata': 'https://www.wikidata.org/wiki/Q5280395', 'display_name': 'Direct thrombin inhibitor', 'level': 5, 'score': 0.5046023}, {'id': 'https://openalex.org/C64489805', 'wikidata': 'https://www.wikidata.org/wiki/Q873864', 'display_name': 'Liquid chromatography–mass spectrometry', 'level': 3, 'score': 0.46851802}, {'id': 'https://openalex.org/C2780077467', 'wikidata': 'https://www.wikidata.org/wiki/Q2520736', 'display_name': 'Thrombin time', 'level': 4, 'score': 0.42919174}, {'id': 'https://openalex.org/C162356407', 'wikidata': 'https://www.wikidata.org/wiki/Q180809', 'display_name': 'Mass spectrometry', 'level': 2, 'score': 0.35814697}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.33922648}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.23342672}, {'id': 'https://openalex.org/C112705442', 'wikidata': 'https://www.wikidata.org/wiki/Q323936', 'display_name': 'Pharmacokinetics', 'level': 2, 'score': 0.20564681}, {'id': 'https://openalex.org/C2778261982', 'wikidata': 'https://www.wikidata.org/wiki/Q1755136', 'display_name': 'Partial thromboplastin time', 'level': 3, 'score': 0.20551571}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.19741666}, {'id': 'https://openalex.org/C2776301958', 'wikidata': 'https://www.wikidata.org/wiki/Q407431', 'display_name': 'Warfarin', 'level': 3, 'score': 0.16257909}, {'id': 'https://openalex.org/C2778382381', 'wikidata': 'https://www.wikidata.org/wiki/Q179217', 'display_name': 'Coagulation', 'level': 2, 'score': 0.1596041}, {'id': 'https://openalex.org/C2779161974', 'wikidata': 'https://www.wikidata.org/wiki/Q815819', 'display_name': 'Atrial fibrillation', 'level': 2, 'score': 0.060590714}], 'mesh': [{'descriptor_ui': 'D001562', 'descriptor_name': 'Benzimidazoles', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D016903', 'descriptor_name': 'Drug Monitoring', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D010314', 'descriptor_name': 'Partial Thromboplastin Time', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D011725', 'descriptor_name': 'Pyridines', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': True}, {'descriptor_ui': 'D013918', 'descriptor_name': 'Thrombin Time', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D000925', 'descriptor_name': 'Anticoagulants', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D000925', 'descriptor_name': 'Anticoagulants', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001562', 'descriptor_name': 'Benzimidazoles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001777', 'descriptor_name': 'Blood Coagulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001777', 'descriptor_name': 'Blood Coagulation', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D002138', 'descriptor_name': 'Calibration', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002853', 'descriptor_name': 'Chromatography, Liquid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002853', 'descriptor_name': 'Chromatography, Liquid', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D000069604', 'descriptor_name': 'Dabigatran', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016903', 'descriptor_name': 'Drug Monitoring', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D064368', 'descriptor_name': 'Healthy Volunteers', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010314', 'descriptor_name': 'Partial Thromboplastin Time', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011725', 'descriptor_name': 'Pyridines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012016', 'descriptor_name': 'Reference Values', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015203', 'descriptor_name': 'Reproducibility of Results', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053719', 'descriptor_name': 'Tandem Mass Spectrometry', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D053719', 'descriptor_name': 'Tandem Mass Spectrometry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013917', 'descriptor_name': 'Thrombin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013917', 'descriptor_name': 'Thrombin', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': False}, {'descriptor_ui': 'D013918', 'descriptor_name': 'Thrombin Time', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1160/th13-03-0202', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S206235894', 'display_name': 'Thrombosis and Haemostasis', 'issn_l': '0340-6245', 'issn': ['0340-6245', '2567-689X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320000', 'host_organization_name': 'Thieme Medical Publishers (Germany)', 'host_organization_lineage': ['https://openalex.org/P4310320000'], 'host_organization_lineage_names': ['Thieme Medical Publishers (Germany)'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/23783171', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'No poverty', 'id': 'https://metadata.un.org/sdg/1', 'score': 0.44}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 17, 'referenced_works': ['https://openalex.org/W1587492601', 'https://openalex.org/W1959502336', 'https://openalex.org/W1979251728', 'https://openalex.org/W2003479746', 'https://openalex.org/W2015940002', 'https://openalex.org/W2023143117', 'https://openalex.org/W2024241508', 'https://openalex.org/W2027863730', 'https://openalex.org/W2033102959', 'https://openalex.org/W2075502536', 'https://openalex.org/W2112991023', 'https://openalex.org/W2113446992', 'https://openalex.org/W2124882231', 'https://openalex.org/W2156970332', 'https://openalex.org/W2158014557', 'https://openalex.org/W2163853479', 'https://openalex.org/W2170703129'], 'related_works': ['https://openalex.org/W2471369460', 'https://openalex.org/W2160160759', 'https://openalex.org/W2146593044', 'https://openalex.org/W2113446992', 'https://openalex.org/W2098356073', 'https://openalex.org/W2039550682', 'https://openalex.org/W2003433167', 'https://openalex.org/W1997970906', 'https://openalex.org/W1981656480', 'https://openalex.org/W1981340953'], 'abstract_inverted_index': {'Ways': [0], 'to': [1, 26, 53, 91, 110, 202, 207, 225], 'monitor': [2], 'dabigatran': [3, 28, 67, 204, 231, 237], 'etexilate': [4], '(DE)': [5], 'therapy': [6], 'would': [7], 'be': [8, 42], 'useful': [9], 'in': [10, 36, 44, 68, 239], 'certain': [11], 'situations.': [12], 'Functional': [13], 'assays': [14, 224], 'such': [15], 'as': [16, 101, 113], 'aPTT': [17, 55, 80, 161, 201], 'or': [18], 'Hemoclot®': [19], 'Thrombin': [20], 'Inhibitor': [21], '(HTI)': [22], 'have': [23], 'been': [24], 'proposed': [25], 'evaluate': [27], 'concentrations,': [29], 'but': [30], 'previous': [31], 'findings': [32], 'are': [33], 'based': [34], 'on': [35], 'vitro': [37], 'studies': [38], 'and': [39, 56, 85, 120, 156, 178, 191, 212], 'results': [40], 'must': [41], 'confirmed': [43], 'clinical': [45], 'samples.': [46], 'The': [47, 96, 104, 126, 160], 'aim': [48], 'of': [49, 66, 133, 152, 200, 222, 230, 235], 'this': [50], 'study': [51], 'was': [52, 81, 88, 108, 149], 'compare': [54], 'HTI': [57, 87, 119, 141, 223], 'measurements': [58, 65], 'with': [59, 167, 176, 180, 195, 215], 'liquid': [60], 'chromatography-tandem': [61], 'mass': [62], 'spectrometry': [63], '(LC-MS/MS)': [64], 'plasma': [69, 76, 105, 168], 'samples': [70, 77], 'from': [71, 93], 'DE': [72], 'treated': [73], 'patients.': [74], 'Seventy-one': [75], 'were': [78], 'included.': [79], 'performed': [82, 89, 142], 'using': [83], 'STA-CKPrest®': [84], 'SynthASil®.': [86], 'according': [90], 'instructions': [92], 'the': [94, 118, 140, 184, 187, 192, 198, 220, 243], 'manufacturer.': [95], 'LC-MS/MS': [97, 121, 148, 172, 196, 216, 245], 'method': [98], 'utilised': [99], 'dabigatran-d3': [100], 'internal': [102], 'standard.': [103], 'concentration': [106], 'range': [107], '0': [109], '645': [111], 'ng/ml': [112, 135], 'measured': [114, 170], 'by': [115, 171], 'LC-MS/MS.': [116], 'Overall,': [117], 'analyses': [122], 'correlated': [123], 'well': [124, 166], '(r²=0.97).': [125], 'Bland-Altman': [127], 'analysis': [128], 'showed': [129], 'a': [130], 'mean': [131], 'difference': [132], '9': [134], '(SD:': [136], '20': [137], 'ng/ml).': [138], 'However,': [139], 'poorly': [143], 'at': [144], 'concentrations': [145, 169, 229], '<50': [146], 'ng/ml.': [147, 233], 'sensitive': [150], '(limit': [151], 'quantification': [153], '1.1': [154], 'ng/ml)': [155], 'specific': [157], 'for': [158], 'dabigatran.': [159], 'methods': [162], 'did': [163], 'not': [164], 'correlate': [165], '(r²': [173], '=': [174], '0.59': [175], 'SynthASil®': [177], '0.50': [179], 'STA-CKPrest®).': [181], 'In': [182], 'conclusion,': [183], 'poor': [185, 193], 'sensitivity,': [186], 'important': [188], 'inter-individual': [189, 210], 'variability,': [190], 'correlation': [194], 'preclude': [197], 'use': [199, 221], 'estimate': [203, 228], 'concentrations.': [205], 'Due': [206], 'its': [208], 'small': [209], 'variability': [211], 'good': [213], 'agreement': [214], 'measurements,': [217], 'we': [218], 'recommend': [219], 'rather': [226], 'accurately': [227], '>50': [232], 'Quantification': [234], 'lower': [236], 'levels': [238], 'DE-treated': [240], 'patients': [241], 'requires': [242], '"reference"': [244], 'method.': [246]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2003433167', 'counts_by_year': [{'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 5}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 11}, {'year': 2017, 'cited_by_count': 6}, {'year': 2016, 'cited_by_count': 13}, {'year': 2015, 'cited_by_count': 24}, {'year': 2014, 'cited_by_count': 24}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-15T09:52:43.020832', 'created_date': '2016-06-24'}