Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2003241066', 'doi': 'https://doi.org/10.1242/dev.00522', 'title': 'Two Pax genes,<i>eye gone</i>and<i>eyeless</i>, act cooperatively in promoting<i>Drosophila</i>eye development', 'display_name': 'Two Pax genes,<i>eye gone</i>and<i>eyeless</i>, act cooperatively in promoting<i>Drosophila</i>eye development', 'publication_year': 2003, 'publication_date': '2003-05-20', 'ids': {'openalex': 'https://openalex.org/W2003241066', 'doi': 'https://doi.org/10.1242/dev.00522', 'mag': '2003241066', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/12756177'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1242/dev.00522', 'pdf_url': 'https://journals.biologists.com/dev/article-pdf/130/13/2939/1143601/2939.pdf', 'source': {'id': 'https://openalex.org/S86558740', 'display_name': 'Development', 'issn_l': '0950-1991', 'issn': ['0950-1991', '1477-9129'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311847', 'host_organization_name': 'The Company of Biologists', 'host_organization_lineage': ['https://openalex.org/P4310311847'], 'host_organization_lineage_names': ['The Company of Biologists'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://journals.biologists.com/dev/article-pdf/130/13/2939/1143601/2939.pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5047713771', 'display_name': 'Chuen-Chuen Jang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I148366613', 'display_name': 'National Yang Ming Chiao Tung University', 'ror': 'https://ror.org/00se2k293', 'country_code': 'TW', 'type': 'education', 'lineage': ['https://openalex.org/I148366613']}, {'id': 'https://openalex.org/I4210136969', 'display_name': 'Institute of Molecular Biology, Academia Sinica', 'ror': 'https://ror.org/047sbcx71', 'country_code': 'TW', 'type': 'facility', 'lineage': ['https://openalex.org/I4210136969', 'https://openalex.org/I84653119']}], 'countries': ['TW'], 'is_corresponding': False, 'raw_author_name': 'Chuen-Chuen Jang', 'raw_affiliation_strings': ['Institute of Genetics, National Yang-Ming University, Taipei 111, Taiwan,Republic of China', 'Institute of Molecular Biology, Academia Sinica, Taipei 11529, Taiwan,Republic of China'], 'affiliations': [{'raw_affiliation_string': 'Institute of Genetics, National Yang-Ming University, Taipei 111, Taiwan,Republic of China', 'institution_ids': ['https://openalex.org/I148366613']}, {'raw_affiliation_string': 'Institute of Molecular Biology, Academia Sinica, Taipei 11529, Taiwan,Republic of China', 'institution_ids': ['https://openalex.org/I4210136969']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5005216320', 'display_name': 'Ju-Lan Chao', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I148366613', 'display_name': 'National Yang Ming Chiao Tung University', 'ror': 'https://ror.org/00se2k293', 'country_code': 'TW', 'type': 'education', 'lineage': ['https://openalex.org/I148366613']}, {'id': 'https://openalex.org/I4210136969', 'display_name': 'Institute of Molecular Biology, Academia Sinica', 'ror': 'https://ror.org/047sbcx71', 'country_code': 'TW', 'type': 'facility', 'lineage': ['https://openalex.org/I4210136969', 'https://openalex.org/I84653119']}], 'countries': ['TW'], 'is_corresponding': False, 'raw_author_name': 'Ju-Lan Chao', 'raw_affiliation_strings': ['Institute of Genetics, National Yang-Ming University, Taipei 111, Taiwan,Republic of China', 'Institute of Molecular Biology, Academia Sinica, Taipei 11529, Taiwan,Republic of China'], 'affiliations': [{'raw_affiliation_string': 'Institute of Genetics, National Yang-Ming University, Taipei 111, Taiwan,Republic of China', 'institution_ids': ['https://openalex.org/I148366613']}, {'raw_affiliation_string': 'Institute of Molecular Biology, Academia Sinica, Taipei 11529, Taiwan,Republic of China', 'institution_ids': ['https://openalex.org/I4210136969']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5074814219', 'display_name': 'Nikolas Jones', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I95457486', 'display_name': 'University of California, Berkeley', 'ror': 'https://ror.org/01an7q238', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I95457486']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Nikolas Jones', 'raw_affiliation_strings': ['Department of Molecular and Cell Biology, University of California, Berkeley,CA 94720-3204, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular and Cell Biology, University of California, Berkeley,CA 94720-3204, USA', 'institution_ids': ['https://openalex.org/I95457486']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110201260', 'display_name': 'Li-Chin Yao', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210136969', 'display_name': 'Institute of Molecular Biology, Academia Sinica', 'ror': 'https://ror.org/047sbcx71', 'country_code': 'TW', 'type': 'facility', 'lineage': ['https://openalex.org/I4210136969', 'https://openalex.org/I84653119']}], 'countries': ['TW'], 'is_corresponding': False, 'raw_author_name': 'Li-Chin Yao', 'raw_affiliation_strings': ['Institute of Molecular Biology, Academia Sinica, Taipei, 11529, Taiwan, Republic of China'], 'affiliations': [{'raw_affiliation_string': 'Institute of Molecular Biology, Academia Sinica, Taipei, 11529, Taiwan, Republic of China', 'institution_ids': ['https://openalex.org/I4210136969']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5017507306', 'display_name': 'Dmitri A. Bessarab', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210136969', 'display_name': 'Institute of Molecular Biology, Academia Sinica', 'ror': 'https://ror.org/047sbcx71', 'country_code': 'TW', 'type': 'facility', 'lineage': ['https://openalex.org/I4210136969', 'https://openalex.org/I84653119']}], 'countries': ['TW'], 'is_corresponding': False, 'raw_author_name': 'Dmitri A. Bessarab', 'raw_affiliation_strings': ['Institute of Molecular Biology, Academia Sinica, Taipei, 11529, Taiwan, Republic of China'], 'affiliations': [{'raw_affiliation_string': 'Institute of Molecular Biology, Academia Sinica, Taipei, 11529, Taiwan, Republic of China', 'institution_ids': ['https://openalex.org/I4210136969']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110278692', 'display_name': 'Yien Ming Kuo', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I95457486', 'display_name': 'University of California, Berkeley', 'ror': 'https://ror.org/01an7q238', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I95457486']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Yien M. Kuo', 'raw_affiliation_strings': ['Department of Molecular and Cell Biology, University of California, Berkeley,CA 94720-3204, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular and Cell Biology, University of California, Berkeley,CA 94720-3204, USA', 'institution_ids': ['https://openalex.org/I95457486']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5008607689', 'display_name': 'Susie Jun', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1344073410', 'display_name': 'Howard Hughes Medical Institute', 'ror': 'https://ror.org/006w34k90', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1344073410']}, {'id': 'https://openalex.org/I83399316', 'display_name': 'Rockefeller University', 'ror': 'https://ror.org/0420db125', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I83399316']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Susie Jun', 'raw_affiliation_strings': ['Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10021, USA'], 'affiliations': [{'raw_affiliation_string': 'Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10021, USA', 'institution_ids': ['https://openalex.org/I1344073410', 'https://openalex.org/I83399316']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5075052493', 'display_name': 'Claude Desplan', 'orcid': 'https://orcid.org/0000-0002-6914-1413'}, 'institutions': [{'id': 'https://openalex.org/I1344073410', 'display_name': 'Howard Hughes Medical Institute', 'ror': 'https://ror.org/006w34k90', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1344073410']}, {'id': 'https://openalex.org/I83399316', 'display_name': 'Rockefeller University', 'ror': 'https://ror.org/0420db125', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I83399316']}, {'id': 'https://openalex.org/I57206974', 'display_name': 'New York University', 'ror': 'https://ror.org/0190ak572', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I57206974']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Claude Desplan', 'raw_affiliation_strings': ['Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10021, USA', 'Present address: Department of Biology, New York University, 1009 Main, 100 Washington Square East, 10003, New York, New York, USA'], 'affiliations': [{'raw_affiliation_string': 'Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10021, USA', 'institution_ids': ['https://openalex.org/I1344073410', 'https://openalex.org/I83399316']}, {'raw_affiliation_string': 'Present address: Department of Biology, New York University, 1009 Main, 100 Washington Square East, 10003, New York, New York, USA', 'institution_ids': ['https://openalex.org/I57206974']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063832815', 'display_name': 'Steven K. Beckendorf', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I95457486', 'display_name': 'University of California, Berkeley', 'ror': 'https://ror.org/01an7q238', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I95457486']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Steven K. Beckendorf', 'raw_affiliation_strings': ['Department of Molecular and Cell Biology, University of California, Berkeley,CA 94720-3204, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Molecular and Cell Biology, University of California, Berkeley,CA 94720-3204, USA', 'institution_ids': ['https://openalex.org/I95457486']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5067668992', 'display_name': 'Y. Henry Sun', 'orcid': 'https://orcid.org/0000-0001-8279-5270'}, 'institutions': [{'id': 'https://openalex.org/I148366613', 'display_name': 'National Yang Ming Chiao Tung University', 'ror': 'https://ror.org/00se2k293', 'country_code': 'TW', 'type': 'education', 'lineage': ['https://openalex.org/I148366613']}, {'id': 'https://openalex.org/I4210136969', 'display_name': 'Institute of Molecular Biology, Academia Sinica', 'ror': 'https://ror.org/047sbcx71', 'country_code': 'TW', 'type': 'facility', 'lineage': ['https://openalex.org/I4210136969', 'https://openalex.org/I84653119']}], 'countries': ['TW'], 'is_corresponding': False, 'raw_author_name': 'Y. Henry Sun', 'raw_affiliation_strings': ['Institute of Genetics, National Yang-Ming University, Taipei 111, Taiwan,Republic of China', 'Institute of Molecular Biology, Academia Sinica, Taipei 11529, Taiwan,Republic of China'], 'affiliations': [{'raw_affiliation_string': 'Institute of Genetics, National Yang-Ming University, Taipei 111, Taiwan,Republic of China', 'institution_ids': ['https://openalex.org/I148366613']}, {'raw_affiliation_string': 'Institute of Molecular Biology, Academia Sinica, Taipei 11529, Taiwan,Republic of China', 'institution_ids': ['https://openalex.org/I4210136969']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 6, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 3.743, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 125, 'citation_normalized_percentile': {'value': 0.999978, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '130', 'issue': '13', 'first_page': '2939', 'last_page': '2951'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10268', 'display_name': 'Developmental Biology and Gene Regulation', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10268', 'display_name': 'Developmental Biology and Gene Regulation', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11077', 'display_name': 'Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities', 'score': 0.9589, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12065', 'display_name': 'Hippo pathway signaling and YAP/TAZ', 'score': 0.9432, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/pax6', 'display_name': 'PAX6', 'score': 0.8390241}, {'id': 'https://openalex.org/keywords/ectopic-expression', 'display_name': 'Ectopic expression', 'score': 0.80232024}], 'concepts': [{'id': 'https://openalex.org/C114696181', 'wikidata': 'https://www.wikidata.org/wiki/Q5422650', 'display_name': 'Eye development', 'level': 4, 'score': 0.9515798}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.88400733}, {'id': 'https://openalex.org/C51816534', 'wikidata': 'https://www.wikidata.org/wiki/Q14916213', 'display_name': 'PAX6', 'level': 4, 'score': 0.8390241}, {'id': 'https://openalex.org/C97037327', 'wikidata': 'https://www.wikidata.org/wiki/Q5334291', 'display_name': 'Ectopic expression', 'level': 3, 'score': 0.80232024}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.51050127}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.50349706}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.46405828}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.45957422}, {'id': 'https://openalex.org/C2909722775', 'wikidata': 'https://www.wikidata.org/wiki/Q942537', 'display_name': 'Compound eye', 'level': 2, 'score': 0.42333975}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.42132488}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C120665830', 'wikidata': 'https://www.wikidata.org/wiki/Q14620', 'display_name': 'Optics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D029721', 'descriptor_name': 'Drosophila Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D004331', 'descriptor_name': 'Drosophila melanogaster', 'qualifier_ui': 'Q000254', 'qualifier_name': 'growth & development', 'is_major_topic': True}, {'descriptor_ui': 'D004628', 'descriptor_name': 'Embryonic Structures', 'qualifier_ui': 'Q000254', 'qualifier_name': 'growth & development', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D029721', 'descriptor_name': 'Drosophila Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D029721', 'descriptor_name': 'Drosophila Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004331', 'descriptor_name': 'Drosophila melanogaster', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004331', 'descriptor_name': 'Drosophila melanogaster', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004331', 'descriptor_name': 'Drosophila melanogaster', 'qualifier_ui': 'Q000196', 'qualifier_name': 'embryology', 'is_major_topic': False}, {'descriptor_ui': 'D004331', 'descriptor_name': 'Drosophila melanogaster', 'qualifier_ui': 'Q000033', 'qualifier_name': 'anatomy & histology', 'is_major_topic': False}, {'descriptor_ui': 'D004628', 'descriptor_name': 'Embryonic Structures', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004628', 'descriptor_name': 'Embryonic Structures', 'qualifier_ui': 'Q000033', 'qualifier_name': 'anatomy & histology', 'is_major_topic': False}, {'descriptor_ui': 'D018507', 'descriptor_name': 'Gene Expression Regulation, Developmental', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017344', 'descriptor_name': 'Genes, Insect', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017403', 'descriptor_name': 'In Situ Hybridization', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010641', 'descriptor_name': 'Phenotype', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017956', 'descriptor_name': 'Photoreceptor Cells, Invertebrate', 'qualifier_ui': 'Q000254', 'qualifier_name': 'growth & development', 'is_major_topic': False}, {'descriptor_ui': 'D017956', 'descriptor_name': 'Photoreceptor Cells, Invertebrate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017956', 'descriptor_name': 'Photoreceptor Cells, Invertebrate', 'qualifier_ui': 'Q000196', 'qualifier_name': 'embryology', 'is_major_topic': False}, {'descriptor_ui': 'D017956', 'descriptor_name': 'Photoreceptor Cells, Invertebrate', 'qualifier_ui': 'Q000033', 'qualifier_name': 'anatomy & histology', 'is_major_topic': False}, {'descriptor_ui': 'D011518', 'descriptor_name': 'Proto-Oncogene Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D011518', 'descriptor_name': 'Proto-Oncogene Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011518', 'descriptor_name': 'Proto-Oncogene Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D014158', 'descriptor_name': 'Transcription, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019076', 'descriptor_name': 'Transgenes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051155', 'descriptor_name': 'Wnt1 Protein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1242/dev.00522', 'pdf_url': 'https://journals.biologists.com/dev/article-pdf/130/13/2939/1143601/2939.pdf', 'source': {'id': 'https://openalex.org/S86558740', 'display_name': 'Development', 'issn_l': '0950-1991', 'issn': ['0950-1991', '1477-9129'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311847', 'host_organization_name': 'The Company of Biologists', 'host_organization_lineage': ['https://openalex.org/P4310311847'], 'host_organization_lineage_names': ['The Company of Biologists'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/12756177', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1242/dev.00522', 'pdf_url': 'https://journals.biologists.com/dev/article-pdf/130/13/2939/1143601/2939.pdf', 'source': {'id': 'https://openalex.org/S86558740', 'display_name': 'Development', 'issn_l': '0950-1991', 'issn': ['0950-1991', '1477-9129'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311847', 'host_organization_name': 'The Company of Biologists', 'host_organization_lineage': ['https://openalex.org/P4310311847'], 'host_organization_lineage_names': ['The Company of Biologists'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 64, 'referenced_works': ['https://openalex.org/W1895850272', 'https://openalex.org/W1939431494', 'https://openalex.org/W1964761197', 'https://openalex.org/W1965210215', 'https://openalex.org/W1981607744', 'https://openalex.org/W1986382645', 'https://openalex.org/W1992635772', 'https://openalex.org/W1994528729', 'https://openalex.org/W1994881558', 'https://openalex.org/W1997301423', 'https://openalex.org/W1997339096', 'https://openalex.org/W2004616894', 'https://openalex.org/W2007054766', 'https://openalex.org/W2014908429', 'https://openalex.org/W2015448530', 'https://openalex.org/W2023229923', 'https://openalex.org/W2027199315', 'https://openalex.org/W2029508750', 'https://openalex.org/W2030814126', 'https://openalex.org/W2046084533', 'https://openalex.org/W2046820750', 'https://openalex.org/W2050566666', 'https://openalex.org/W2063985696', 'https://openalex.org/W2064121506', 'https://openalex.org/W2070250500', 'https://openalex.org/W2071575397', 'https://openalex.org/W2076242116', 'https://openalex.org/W2088541123', 'https://openalex.org/W2089208780', 'https://openalex.org/W2094598747', 'https://openalex.org/W2097038192', 'https://openalex.org/W2099805939', 'https://openalex.org/W2102589238', 'https://openalex.org/W2104104103', 'https://openalex.org/W2109204015', 'https://openalex.org/W2110643873', 'https://openalex.org/W2114892387', 'https://openalex.org/W2120213194', 'https://openalex.org/W2120272758', 'https://openalex.org/W2120995883', 'https://openalex.org/W2121784339', 'https://openalex.org/W2122289311', 'https://openalex.org/W2129763289', 'https://openalex.org/W2131906224', 'https://openalex.org/W2139587743', 'https://openalex.org/W2141652419', 'https://openalex.org/W2144267063', 'https://openalex.org/W2151011371', 'https://openalex.org/W2151547320', 'https://openalex.org/W2152032402', 'https://openalex.org/W2152442542', 'https://openalex.org/W2155825305', 'https://openalex.org/W2159935247', 'https://openalex.org/W2160222217', 'https://openalex.org/W2163573865', 'https://openalex.org/W2165089629', 'https://openalex.org/W2168081141', 'https://openalex.org/W2169536561', 'https://openalex.org/W2169988786', 'https://openalex.org/W2172162107', 'https://openalex.org/W2175560053', 'https://openalex.org/W2185144948', 'https://openalex.org/W2187079233', 'https://openalex.org/W4388299216'], 'related_works': ['https://openalex.org/W2149404122', 'https://openalex.org/W2144745574', 'https://openalex.org/W2134321528', 'https://openalex.org/W2005943162', 'https://openalex.org/W2003241066', 'https://openalex.org/W1999893499', 'https://openalex.org/W1973776426', 'https://openalex.org/W1589588578', 'https://openalex.org/W1566190075', 'https://openalex.org/W11768714'], 'abstract_inverted_index': {'We': [0], 'report': [1], 'the': [2, 26, 30, 102, 105, 137], 'identification': [3], 'of': [4, 25, 37, 54, 104, 110, 118, 147], 'a': [5, 115], 'Drosophila': [6], 'Pax': [7], 'gene,': [8, 34], 'eye': [9, 16, 41, 90, 120, 138, 143], 'gone': [10], '(eyg),': [11], 'which': [12], 'is': [13, 65], 'required': [14], 'for': [15, 101], 'development.': [17], 'Loss-of-function': [18], 'eyg': [19, 38, 63, 95, 111, 127], 'mutations': [20], 'cause': [21], 'reduction': [22], 'or': [23], 'absence': [24], 'eye.': [27], 'Similar': [28], 'to': [29, 132, 141], 'Pax6': [31], 'eyeless': [32], '(ey)': [33], 'ectopic': [35, 78, 89, 119], 'expression': [36, 64], 'induces': [39], 'extra': [40], 'formation,': [42], 'but': [43], 'at': [44], 'sites': [45], 'different': [46], 'from': [47], 'those': [48], 'induced': [49], 'by': [50, 68], 'ey.': [51], 'Several': [52], 'lines': [53], 'evidence': [55], 'suggest': [56], 'that': [57, 126], 'eygand': [58], 'ey': [59, 74, 97, 113], 'act': [60], 'cooperatively:': [61], '(1)': [62], 'not': [66, 83], 'regulated': [67], 'ey,': [69, 85], 'nor': [70, 86], 'does': [71, 82, 87], 'it': [72], 'regulate': [73], 'expression,': [75], '(2)': [76], 'eyg-induced': [77], 'morphogenetic': [79], 'furrow': [80], 'formation': [81], 'require': [84, 92], 'ey-induced': [88], 'production': [91], 'eyg,': [93], '(3)': [94], 'and': [96, 107, 112, 140], 'can': [98], 'partially': [99], 'substitute': [100], 'function': [103], 'other,': [106], '(4)': [108], 'coexpression': [109], 'has': [114, 128], 'synergistic': [116], 'enhancement': [117], 'formation.': [121], 'Our': [122], 'results': [123], 'also': [124], 'show': [125], 'two': [129], 'major': [130], 'functions:': [131], 'promote': [133, 142], 'cell': [134], 'proliferation': [135], 'in': [136], 'disc': [139], 'development': [144], 'through': [145], 'suppression': [146], 'wg': [148], 'transcription.': [149]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2003241066', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 6}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 7}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 4}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 12}], 'updated_date': '2024-12-15T19:08:22.516289', 'created_date': '2016-06-24'}