Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2003109865', 'doi': 'https://doi.org/10.1002/art.1780400333', 'title': 'Serum biologic markers as predictors of disease progression in osteoarthritis of the knee', 'display_name': 'Serum biologic markers as predictors of disease progression in osteoarthritis of the knee', 'publication_year': 1997, 'publication_date': '1997-03-01', 'ids': {'openalex': 'https://openalex.org/W2003109865', 'doi': 'https://doi.org/10.1002/art.1780400333', 'mag': '2003109865', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/9082954'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/art.1780400333', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S132787887', 'display_name': 'Arthritis & Rheumatism', 'issn_l': '0004-3591', 'issn': ['0004-3591', '1529-0131'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'letter', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5058613002', 'display_name': 'Claire Georges', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210092774', 'display_name': 'Hôpital Cochin', 'ror': 'https://ror.org/00ph8tk69', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210092774', 'https://openalex.org/I4210097159', 'https://openalex.org/I4210124464']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Claire Georges', 'raw_affiliation_strings': ['Cochin Hospital Paris, France'], 'affiliations': [{'raw_affiliation_string': 'Cochin Hospital Paris, France', 'institution_ids': ['https://openalex.org/I4210092774']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5053153290', 'display_name': 'Hélène Vigneron', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210092774', 'display_name': 'Hôpital Cochin', 'ror': 'https://ror.org/00ph8tk69', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210092774', 'https://openalex.org/I4210097159', 'https://openalex.org/I4210124464']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Hélène Vigneron', 'raw_affiliation_strings': ['Cochin Hospital Paris, France'], 'affiliations': [{'raw_affiliation_string': 'Cochin Hospital Paris, France', 'institution_ids': ['https://openalex.org/I4210092774']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5060426202', 'display_name': 'X Ayral', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210092774', 'display_name': 'Hôpital Cochin', 'ror': 'https://ror.org/00ph8tk69', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210092774', 'https://openalex.org/I4210097159', 'https://openalex.org/I4210124464']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Xavier Ayral', 'raw_affiliation_strings': ['Cochin Hospital Paris, France'], 'affiliations': [{'raw_affiliation_string': 'Cochin Hospital Paris, France', 'institution_ids': ['https://openalex.org/I4210092774']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5064288864', 'display_name': 'V. Listrat', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210092774', 'display_name': 'Hôpital Cochin', 'ror': 'https://ror.org/00ph8tk69', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210092774', 'https://openalex.org/I4210097159', 'https://openalex.org/I4210124464']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Véronique Listrat', 'raw_affiliation_strings': ['Cochin Hospital Paris, France'], 'affiliations': [{'raw_affiliation_string': 'Cochin Hospital Paris, France', 'institution_ids': ['https://openalex.org/I4210092774']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050180409', 'display_name': 'Philippe Ravaud', 'orcid': 'https://orcid.org/0000-0001-8264-9206'}, 'institutions': [{'id': 'https://openalex.org/I4210092774', 'display_name': 'Hôpital Cochin', 'ror': 'https://ror.org/00ph8tk69', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210092774', 'https://openalex.org/I4210097159', 'https://openalex.org/I4210124464']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Philippe Ravaud', 'raw_affiliation_strings': ['Cochin Hospital Paris, France'], 'affiliations': [{'raw_affiliation_string': 'Cochin Hospital Paris, France', 'institution_ids': ['https://openalex.org/I4210092774']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5108092302', 'display_name': 'Maxime Dougados', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210092774', 'display_name': 'Hôpital Cochin', 'ror': 'https://ror.org/00ph8tk69', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210092774', 'https://openalex.org/I4210097159', 'https://openalex.org/I4210124464']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Maxime Dougados', 'raw_affiliation_strings': ['Cochin Hospital Paris, France'], 'affiliations': [{'raw_affiliation_string': 'Cochin Hospital Paris, France', 'institution_ids': ['https://openalex.org/I4210092774']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013899119', 'display_name': 'Mohammed Sharif', 'orcid': 'https://orcid.org/0000-0001-9723-6295'}, 'institutions': [{'id': 'https://openalex.org/I2802901496', 'display_name': 'Bristol Royal Infirmary', 'ror': 'https://ror.org/031p4kj21', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802901496']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Mohammed Sharif', 'raw_affiliation_strings': ['Bristol Royal Infirmary Bristol, UK.'], 'affiliations': [{'raw_affiliation_string': 'Bristol Royal Infirmary Bristol, UK.', 'institution_ids': ['https://openalex.org/I2802901496']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113680226', 'display_name': 'Paul Dieppe', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2802901496', 'display_name': 'Bristol Royal Infirmary', 'ror': 'https://ror.org/031p4kj21', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802901496']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Paul Dieppe', 'raw_affiliation_strings': ['Bristol Royal Infirmary Bristol, UK.'], 'affiliations': [{'raw_affiliation_string': 'Bristol Royal Infirmary Bristol, UK.', 'institution_ids': ['https://openalex.org/I2802901496']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5015932797', 'display_name': 'Tore Saxne', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I187531555', 'display_name': 'Lund University', 'ror': 'https://ror.org/012a77v79', 'country_code': 'SE', 'type': 'education', 'lineage': ['https://openalex.org/I187531555']}], 'countries': ['SE'], 'is_corresponding': False, 'raw_author_name': 'Tore Saxne', 'raw_affiliation_strings': ['Lund University Hospital, Lund, Sweden,'], 'affiliations': [{'raw_affiliation_string': 'Lund University Hospital, Lund, Sweden,', 'institution_ids': ['https://openalex.org/I187531555']}]}], 'institution_assertions': [], 'countries_distinct_count': 3, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': None, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 27, 'citation_normalized_percentile': {'value': 0.906977, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 87, 'max': 88}, 'biblio': {'volume': '40', 'issue': '3', 'first_page': '590', 'last_page': '591'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10105', 'display_name': 'Osteoarthritis Treatment and Mechanisms', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10105', 'display_name': 'Osteoarthritis Treatment and Mechanisms', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12800', 'display_name': 'Musculoskeletal synovial abnormalities and treatments', 'score': 0.9968, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10200', 'display_name': 'Rheumatoid Arthritis Research and Therapies', 'score': 0.9944, 'subfield': {'id': 'https://openalex.org/subfields/2745', 'display_name': 'Rheumatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.53255713}], 'mesh': [{'descriptor_ui': 'D015415', 'descriptor_name': 'Biomarkers', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': True}, {'descriptor_ui': 'D007719', 'descriptor_name': 'Knee Joint', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D010003', 'descriptor_name': 'Osteoarthritis', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': True}, {'descriptor_ui': 'D015415', 'descriptor_name': 'Biomarkers', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018450', 'descriptor_name': 'Disease Progression', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007719', 'descriptor_name': 'Knee Joint', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D010003', 'descriptor_name': 'Osteoarthritis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010003', 'descriptor_name': 'Osteoarthritis', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D011379', 'descriptor_name': 'Prognosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/art.1780400333', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S132787887', 'display_name': 'Arthritis & Rheumatism', 'issn_l': '0004-3591', 'issn': ['0004-3591', '1529-0131'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9082954', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.59, 'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 6, 'referenced_works': ['https://openalex.org/W161235914', 'https://openalex.org/W2116959483', 'https://openalex.org/W2133485385', 'https://openalex.org/W2150579918', 'https://openalex.org/W3212073397', 'https://openalex.org/W61386510'], 'related_works': ['https://openalex.org/W4389568370', 'https://openalex.org/W3108674512', 'https://openalex.org/W3032375762', 'https://openalex.org/W3031052312', 'https://openalex.org/W2748952813', 'https://openalex.org/W2586801360', 'https://openalex.org/W2080531066', 'https://openalex.org/W1995515455', 'https://openalex.org/W1506200166', 'https://openalex.org/W1489783725'], 'abstract_inverted_index': {'Arthritis': [0], '&': [1], 'RheumatismVolume': [2], '40,': [3], 'Issue': [4], '3': [5], 'p.': [6], '590-591': [7, 389], 'LetterFree': [8], 'to': [9, 312, 334, 357], 'Read': [10], 'Serum': [11], 'biologic': [12], 'markers': [13], 'as': [14], 'predictors': [15], 'of': [16, 21, 328, 338, 351, 362], 'disease': [17], 'progression': [18], 'in': [19], 'osteoarthritis': [20], 'the': [22, 344, 354], 'knee': [23], 'Claire': [24, 27, 163, 166], 'Georges': [25, 28, 164, 167], 'MD,': [26, 41, 56, 71, 86, 101, 116, 132, 148, 165, 180, 195, 210, 225, 240, 255, 271, 287], 'MD': [29, 44, 59, 74, 89, 104, 119, 135, 151, 168, 183, 198, 213, 228, 243, 258, 274, 290], 'Cochin': [30, 45, 60, 75, 90, 105, 169, 184, 199, 214, 229, 244], 'Hospital': [31, 46, 61, 76, 91, 106, 154, 170, 185, 200, 215, 230, 245, 293], 'Paris,': [32, 47, 62, 77, 92, 107, 171, 186, 201, 216, 231, 246], 'FranceSearch': [33, 48, 63, 78, 93, 108, 172, 187, 202, 217, 232, 247], 'for': [34, 49, 64, 79, 94, 109, 125, 141, 157, 173, 188, 203, 218, 233, 248, 264, 280, 296, 382], 'more': [35, 50, 65, 80, 95, 110, 126, 142, 158, 174, 189, 204, 219, 234, 249, 265, 281, 297], 'papers': [36, 51, 66, 81, 96, 111, 127, 143, 159, 175, 190, 205, 220, 235, 250, 266, 282, 298], 'by': [37, 52, 67, 82, 97, 112, 128, 144, 160, 176, 191, 206, 221, 236, 251, 267, 283, 299], 'this': [38, 53, 68, 83, 98, 113, 129, 145, 161, 177, 192, 207, 222, 237, 252, 268, 284, 300, 363, 383], 'authorHélène': [39, 178], 'Vigneron': [40, 43, 179, 182], 'Hélène': [42, 181], 'authorXavier': [54, 193], 'Ayral': [55, 58, 194, 197], 'Xavier': [57, 196], 'authorVéronique': [69, 208], 'Listrat': [70, 73, 209, 212], 'Véronique': [72, 211], 'authorPhilippe': [84, 223], 'Ravaud': [85, 88, 224, 227], 'Philippe': [87, 226], 'authorMaxime': [99, 238], 'Dougados': [100, 103, 239, 242], 'Maxime': [102, 241], 'authorMohammed': [114, 253], 'Sharif': [115, 118, 254, 257], 'Mohammed': [117, 256], 'Bristol': [120, 136, 259, 275], 'Royal': [121, 137, 260, 276], 'Infirmary': [122, 138, 261, 277], 'Bristol,': [123, 139, 262, 278], 'UKSearch': [124, 140, 263, 279], 'authorPaul': [130, 269], 'Dieppe': [131, 134, 270, 273], 'Paul': [133, 272], 'authorTore': [146, 285], 'Saxne': [147, 150, 286, 289], 'Tore': [149, 288], 'Lund': [152, 291], 'University': [153, 292], 'Lund,': [155, 294], 'SwedenSearch': [156, 295], 'author': [162, 301], 'First': [302], 'published:': [303], '12': [304], 'December': [305], '2005': [306], 'https://doi.org/10.1002/art.1780400333Citations:': [307], '22AboutPDF': [308], 'ToolsRequest': [309], 'permissionExport': [310], 'citationAdd': [311], 'favoritesTrack': [313], 'citation': [314], 'ShareShare': [315], 'Give': [316], 'accessShare': [317, 320], 'full': [318], 'text': [319], 'full-text': [321, 336, 360], 'accessPlease': [322], 'review': [323], 'our': [324], 'Terms': [325, 348], 'and': [326, 330, 342, 349, 368], 'Conditions': [327, 350], 'Use': [329], 'check': [331], 'box': [332], 'below': [333, 356], 'share': [335, 358], 'version': [337, 361], 'article.I': [339], 'have': [340], 'read': [341], 'accept': [343], 'Wiley': [345], 'Online': [346], 'Library': [347], 'UseShareable': [352], 'LinkUse': [353], 'link': [355], 'a': [359, 374], 'article': [364], 'with': [365], 'your': [366], 'friends': [367], 'colleagues.': [369], 'Learn': [370], 'more.Copy': [371], 'URL': [372], 'Share': [373], 'linkShare': [375], 'onFacebookTwitterLinked': [376], 'InRedditWechat': [377], 'No': [378], 'abstract': [379], 'is': [380], 'available': [381], 'article.Citing': [384], 'Literature': [385], 'Volume40,': [386], 'Issue3March': [387], '1997Pages': [388], 'RelatedInformation': [390]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2003109865', 'counts_by_year': [{'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-12T03:42:45.644046', 'created_date': '2016-06-24'}