Title: Antibody-producing cells in human periapical granulomas and cysts
Abstract: Immunoglobulin-producing cells were quantitated in 20 human periapical granulomas and cysts. Results showed that 42% of the lymphoid cells comprising 19% of all inflammatory cells contained immunoglobulins. The majority of lymphocytes (81%) were not associated with immunoglobulin production. IgG was found in 74%, IgA in 20%, IgE in 4%, and IgM in 2% of the immunoglobulin-positive cells. Pain did not correlate with any measurable change in the distribution of immunoglobulin-positive cells or other inflammatory cells. Endodontic treatment of inflamed pulps did not alter the lesional distribution of immunoglobulin-positive cells compared with the distribution that prevailed in untreated patients. There were no significant differences in immunoglobulin distribution between the solid and cystic forms of the periapical lesions. Immunoglobulin-producing cells were quantitated in 20 human periapical granulomas and cysts. Results showed that 42% of the lymphoid cells comprising 19% of all inflammatory cells contained immunoglobulins. The majority of lymphocytes (81%) were not associated with immunoglobulin production. IgG was found in 74%, IgA in 20%, IgE in 4%, and IgM in 2% of the immunoglobulin-positive cells. Pain did not correlate with any measurable change in the distribution of immunoglobulin-positive cells or other inflammatory cells. Endodontic treatment of inflamed pulps did not alter the lesional distribution of immunoglobulin-positive cells compared with the distribution that prevailed in untreated patients. There were no significant differences in immunoglobulin distribution between the solid and cystic forms of the periapical lesions.
Publication Year: 1981
Publication Date: 1981-01-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
Access and Citation
Cited By Count: 61
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