Publication Information

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'Significant': [8, 1689, 1939, 2003], 'Prostate': [9, 13, 1040, 1055, 1157, 1317, 1325, 1367, 1422, 1532, 1591, 1640, 1690, 1702, 1741, 1781, 1800, 1848, 1896, 1940, 1948, 1991, 1996, 2004, 2061, 2069, 2125, 2169, 2215, 2282, 2397, 2514], 'Cancer': [10, 522, 1041, 1158, 1210, 1533, 1641, 1691], 'Using': [11, 1168, 1490], 'Template': [12, 1119, 1165, 1217, 1315, 1701, 1846, 1895, 1995], 'Mapping': [14, 1120, 1166, 1218, 1703, 1897], 'Biopsy': [15, 1116, 1167, 1176, 1311, 1318, 1433, 1488, 1849, 1855, 1992, 1997, 2062, 2121, 2161, 2208], 'Hashim': [16, 37, 2249], 'Uddin': [17, 38, 40, 2250], 'Ahmed,': [18], 'Yipeng': [19, 55, 2289], 'Hu,': [20], 'Tim': [21, 70, 2310], 'Carter,': [22], 'Nimalan': [23, 85, 2335], 'Arumainayagam,': [24], 'Emilie': [25, 101, 2354], 'Lecornet,': [26], 'Alex': [27, 118, 2374], 'Freeman,': [28], 'David': [29, 137, 2404], 'Hawkes,': [30], 'Dean': [31, 152, 2431], 'C.': [32, 153, 155, 2432], 'Barratt,': [33], 'and': [34, 45, 91, 169, 176, 199, 240, 249, 283, 291, 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148, 164, 165, 181, 182, 209, 2260, 2261, 2298, 2299, 2319, 2320, 2345, 2346, 2388, 2413, 2414, 2441, 2442, 2467, 2468, 2495], 'United': [52, 67, 82, 98, 134, 149, 166, 183, 210, 2262, 2300, 2321, 2347, 2389, 2415, 2443, 2469, 2496], 'Kingdom': [53, 68, 83, 99, 135, 150, 167, 184, 211, 2263, 2301, 2322, 2348, 2390, 2416, 2444, 2470, 2497], ',': [54, 69, 84, 100, 117, 136, 151, 168], 'HuYipeng': [56], 'Hu': [57, 1398, 1882, 2141, 2290], 'Centre': [58, 73, 109, 140, 157, 198, 2291, 2312, 2361, 2406, 2434, 2484], 'for': [59, 74, 141, 158, 192, 400, 518, 617, 622, 666, 705, 724, 797, 827, 867, 906, 1221, 1319, 1589, 1636, 2122, 2163, 2200, 2210, 2292, 2313, 2407, 2435, 2478], 'Medical': [60, 75, 142, 159, 2276, 2293, 2314, 2408, 2436, 2507], 'Image': [61, 76, 143, 160, 1049, 1427, 1989, 2294, 2315, 2409, 2437], 'Computing,': [62, 77, 144, 161, 2295, 2316, 2410, 2438], 'CarterTim': [71], 'Carter': [72, 2311], 'ArumainayagamNimalan': [86], 'Arumainayagam': [87, 2336], 'LecornetEmilie': [102], 'Lecornet': [103, 2355], 'Service': [104, 130, 2356, 2385], "d'Urologie,": [105, 2357], 'Hôpital': [106, 2358], 'Claude': [107, 2359], 'Huriez,': [108, 2360], 'Hospitalier': [110, 2362], 'Régional': [111, 2363], 'Universitaire': [112, 2364], 'de': [113, 2365], 'Lille,': [114, 115, 2366, 2367], 'France': [116, 2368], 'FreemanAlex': [119], 'Freeman': [120, 1082, 1193, 1394, 1569, 1669, 1876, 1972, 2375], 'Department': [121, 2376], 'Histopathology,': [123, 2378], 'London': [126, 189, 2381, 2475], 'Hospitals': [127, 2382], 'National': [128, 190, 2383, 2476], 'Health': [129, 193, 2384, 2479], 'Foundation': [131, 2386], 'Trust,': [132, 2387], 'HawkesDavid': [138], 'Hawkes': [139, 1396, 2149, 2405], 'BarrattDean': [154], 'Barratt': [156, 1390, 2147, 2433], 'EmbertonMark': [171], 'Hospital/University': [187, 2473], 'Institute': [191, 2477], 'Research': [194, 197, 2480, 2483], 'Comprehensive': [195, 2481], 'Biomedical': [196, 2482], 'Clinical': [200, 769, 880, 2056, 2486], 'Effectiveness': [201, 2487], 'Unit,': [202, 2488], 'Royal': [203, 2489], 'Surgeons': [206, 2492], 'England,': [208, 2494], 'View': [212], 'All': [213, 2522], 'Author': [214], 'Informationhttps://doi.org/10.1016/j.juro.2011.03.147AboutFull': [215], 'TextPDF': [216], 'ToolsAdd': [217], 'to': [218, 246, 316, 326, 371, 385, 476, 493, 663, 683, 823, 1117, 1540, 1693, 2058], 'favoritesDownload': [219], 'CitationsTrack': [220], 'CitationsPermissionsReprints': [221], 'ShareFacebookLinked': [222], 'InTwitterEmail': [223], 'Abstract': [224], 'Purpose:': [225], 'Definitions': [226, 338], 'prostate': [228, 259, 274, 306, 375, 486, 499, 520, 531, 540, 563, 580, 615, 646, 657, 669, 691, 707, 772, 779, 800, 830, 846, 871, 893, 908, 925, 940], 'cancer': [229, 238, 293, 342, 351, 393, 433, 466, 541, 616, 670, 801, 869], 'risk': [230, 268, 494], 'are': [231], 'limited': [232], 'since': [233], 'accurate': [234, 267], 'attribution': [235], 'the': [237, 247, 272, 558, 569, 618, 642, 793, 922, 958, 1130, 1320, 1362, 1435, 1637, 1790, 1891, 1999, 2164, 2206], 'grade': [239, 349], 'burden': [241, 352, 467], 'is': [242], 'not': [243], 'possible': [244], 'due': [245], 'random': [248], 'systematic': [250], 'errors': [251, 315], 'associated': [252], 'with': [253, 469, 497, 514, 755, 891, 1480, 1543, 1634, 1856, 1894, 2065, 2212, 2272, 2328, 2396, 2422, 2450, 2503], 'transrectal': [254], 'ultrasound': [255], 'guided': [256], 'biopsy.': [257, 780], 'Transperineal': [258, 485, 579, 1054, 1118, 1216, 1314, 1420, 1845, 1986, 1994, 2119], 'mapping': [260, 275, 307, 487, 532], 'biopsy': [261, 276, 533, 556, 703], 'may': [262, 488], 'have': [263], 'a': [264, 345, 401, 535, 565, 584, 774, 803, 807, 825, 886, 943, 1169, 1483], 'role': [265, 610, 826], 'in': [266, 557, 596, 614, 939, 1129, 1175, 1361, 1429, 1434, 1632, 1698, 1737, 1798, 1998, 2063], 'stratification.': [269], 'We': [270, 302, 387, 463], 'defined': [271], 'transperineal': [273, 305, 778], 'characteristics': [277, 644], 'clinically': [279, 340, 481, 798], 'significant': [280, 341, 482, 537], 'disease.': [281, 483], 'Materials': [282], 'Methods:': [284], 'A': [285, 789, 1037, 1369, 1581, 2152, 2171], '3-dimensional': [286], 'model': [287], 'each': [289], 'gland': [290], 'individual': [292], 'was': [294, 364, 378, 420, 452], 'reconstructed': [295, 388], 'using': [296, 802], '107': [297], 'radical': [298, 516], 'whole': [299], 'mount': [300], 'specimens.': [301, 760], 'performed': [303], '500': [304], 'simulations': [308], 'per': [309], 'case': [310], 'by': [311, 979, 1123, 1262, 1313, 2238, 2286, 2307, 2332, 2351, 2371, 2401, 2428, 2454, 2518], 'varying': [312], 'needle': [313], 'targeting': [314], 'calculate': [317], 'sensitivity,': [318], 'specificity,': [319], 'negative': [321, 597], 'positive': [323, 398], 'predictive': [324], 'value': [325], 'detect': [327], 'lesions': [328, 410, 442], '0.2': [329, 416, 448], 'ml': [330, 335, 412, 417, 444, 449], 'or': [331, 333, 336, 413, 418, 423, 428, 445, 450, 455, 460], 'greater,': [332, 429, 461], '0.5': [334, 411, 443], 'greater.': [337], 'based': [343], 'on': [344, 539, 592, 961, 1215], 'combination': [346], 'Gleason': [348, 473, 842], '(cancer': [353], 'core': [354, 394, 434, 586], 'length)': [355], 'were': [356], 'derived.': [357], 'Results:': [358], 'Mean': [359], '±': [360, 366, 380], 'SD': [361], 'patient': [362], 'age': [363], '61': [365], '6.4': [367], 'years': [368], '(range': [369, 383], '44': [370], '74)': [372], 'mean': [374], 'specific': [376], 'antigen': [377], '9.7': [379], '5.9': [381], 'ng/ml': [382], '0.8': [384], '36.2).': [386], '665': [389], 'foci.': [390], 'The': [391, 431, 501, 609, 633, 719, 918, 1627, 1685, 2157], 'total': [392], 'length': [395, 435], 'from': [396, 942, 957], 'all': [397], 'biopsies': [399], 'particular': [402], 'lesion': [403, 635, 920], 'that': [404, 436, 503, 589, 1495], 'detected': [405, 437], 'more': [406, 438], 'than': [407, 439], '95%': [408, 440], 'greater': [414, 419, 424, 446, 451, 456], '10': [421, 717], 'mm': [422, 427, 454, 459], '6': [426, 453, 631], 'respectively.': [430, 462], 'maximum': [432], '4': [458, 475, 577, 851, 853], 'combined': [464], 'these': [465], 'thresholds': [468], 'dominant': [470], 'nondominant': [472], 'pattern': [474, 588], 'derive': [477], '2': [478, 528], 'definitions': [479, 502], 'Conclusions:': [484], 'provide': [489], 'an': [490, 639], 'effective': [491], 'method': [492, 723], 'stratify': [495], 'men': [496], 'localized': [498, 519, 706, 892], 'cancer.': [500, 521, 647, 692, 708, 872, 894, 909, 926], 'we': [504], 'present': [505], 'require': [506], 'prospective': [507], 'validation.': [508], 'References': [509], '1': [510], ':': [511, 529, 551, 578, 608, 632, 655, 678, 699, 718, 735, 750, 768, 788, 819, 841, 864, 879, 903, 917, 936, 953], 'Active': [512, 904, 1738, 2201], 'surveillance': [513, 889, 905], 'selective': [515], 'treatment': [517, 667], 'J2007;': [523], '13:': [524], '289.': [525], 'Google': [526, 548, 575, 605, 629, 652, 675, 696, 715, 732, 747, 765, 785, 816, 838, 861, 876, 900, 914, 933, 950, 975], 'Scholar': [527, 549, 576, 606, 630, 653, 676, 697, 716, 733, 748, 766, 786, 817, 839, 862, 877, 901, 915, 934, 951, 976], 'Three-dimensional': [530, 700], 'has': [534], 'potentially': [536], 'impact': [538], 'management.': [542], 'J': [543, 625, 727, 811, 856, 895, 929, 946, 1981], 'Clin': [544, 834, 857, 896], 'Oncol2009;': [545, 835], '27:': [546, 859], '4321.': [547], '3': [550, 849, 1598], 'Extended': [552], 'saturation': [554], 'prostatic': [555], 'diagnosis': [559], 'characterisation': [561], 'cancer:': [564, 658, 773, 847], 'critical': [566, 790], 'analysis': [567, 582, 640, 791], 'literature.': [570], 'Eur': [571], 'Urol2007;': [572], '52:': [573], '1309.': [574], 'biopsy:': [581], 'uniform': [585], 'sampling': [587], 'yields': [590], 'data': [591, 804], 'tumor': [593, 612, 661, 685, 794], 'volume': [594, 662, 795], 'limits': [595], 'biopsies.': [598], 'Theor': [599], 'Biol': [600], 'Med': [601, 710, 743], 'Model2010;': [602], '7:': [603], '23.': [604], '5': [607], 'focality': [613], 'selection': [619], 'patients': [621], 'focal': [623, 637], 'therapy.': [624], 'Urol2009;': [626], '181:': [627], '491.': [628], 'index': [634, 919], 'therapy:': [638], 'pathological': [643], 'BJU': [648, 781], 'Int2010;': [649], '106:': [650], '1607.': [651], '7': [654], 'Localized': [656, 1366, 1590, 1799, 2068], 'Relationship': [659], 'clinical': [664, 681], 'significance': [665], '.': [671], 'Cancer1993;': [672], '71:': [673], '933.': [674], '8': [677], 'Pathologic': [679], 'findings': [682], 'predict': [684], 'extent': [686], 'nonpalpable': [688], '(stage': [689], 'T1c)': [690], 'JAMA1994;': [693], '271:': [694], '368.': [695], '9': [698], 'modeling': [701], 'protocols': [704], 'Comput': [709], 'Imaging': [711, 1127, 1306, 1360, 1529, 1736, 1797, 1853, 2054, 2114], 'Graph1998;': [712], '22:': [713], '229.': [714], 'principal': [720], 'axes': [721], 'transformation–a': [722], 'image': [725], 'registration.': [726], 'Nucl': [728], 'Med1990;': [729], '31:': [730], '1717.': [731], '11': [734], 'Shape-based': [736], 'interpolation': [737], 'multidimensional': [739], 'objects.': [740], 'IEEE': [741], 'Trans': [742], 'Imaging1990;': [744], '9:': [745], '32.': [746], '12': [749], 'Tissue': [751], 'shrinkage': [752], 'after': [753], 'fixation': [754], 'formalin': [756], 'injection': [757], 'prostatectomy': [759], 'Virchows': [761], 'Arch2006;': [762], '449:': [763], '297.': [764], '13': [767], 'staging': [770], 'computer-simulated': [775], 'study': [776, 2265, 2303], 'Int2005;': [782], '96:': [783], '999.': [784], '14': [787], 'threshold': [796], 'insignificant': [799], 'set': [805], 'randomized': [808], 'screening': [809, 866], 'trial.': [810], 'Urol2011;': [812], '185:': [813], '121.': [814], 'Link,': [815], '15': [818], 'Is': [820], 'it': [821], 'time': [822], 'consider': [824], 'MRI': [828], 'before': [829], 'biopsy?.': [831], 'Nat': [832], 'Rev': [833], '6:': [836], '197.': [837], '16': [840], 'score': [843], 'lethal': [845], 'does': [848], '+': [850, 854], '=': [852], '3?.': [855], 'Onc2009;': [858], '3459.': [860], '17': [863], 'Rethinking': [865], 'breast': [868], 'JAMA2009;': [873], '302:': [874], '1685.': [875], '18': [878], 'results': [881], 'long-term': [883], 'follow-up': [884], 'large,': [887], 'active': [888], 'cohort': [890], 'Oncol2010;': [897], '28:': [898], '126.': [899], '19': [902], 'low-risk': [907], 'Anticancer': [910], 'Res2010;': [911], '30:': [912], '3683.': [913], '20': [916], 'origin': [923], 'N': [927], 'Engl': [928], 'Med2009;': [930], '361:': [931], '1704.': [932], '21': [935], 'Focal': [937, 962, 1222, 1258, 1586], 'therapy': [938], 'cancer-report': [941], 'consensus': [944, 955], 'panel.': [945], 'Endourol2010;': [947], '24:': [948], '775.': [949], '22': [952], 'Group': [954], 'reports': [956], 'Consensus': [959], 'Conference': [960], 'Treatment': [963], 'Prostatic': [965], 'Carcinoma,': [966], 'Celebration,': [967], 'Florida,': [968], 'February': [969], '24,': [970], '2006.': [971], 'Urology2007;': [972], '70:': [973], '42.': [974], '©': [977], '2011': [978, 2237], 'American': [980, 2239], 'Urological': [981, 2240], 'Association': [982, 2241], 'Education': [983, 2242], 'Research,': [985, 2244], 'Inc.FiguresReferencesRelatedDetailsCited': [986], 'ByKhoo': [987], 'C,': [988, 1068, 1095, 1338, 1340, 1401, 1405, 1461, 1612, 1656, 1672, 1768, 1819, 1823, 1829, 1875, 1879, 1965, 1975, 2023, 2144, 2191], 'Eldred-Evans': [989], 'D,': [990, 1006, 1018, 1024, 1101, 1245, 1344, 1391, 1397, 1514, 1610, 1722, 1928, 2148, 2150], 'Peters': [991, 1199], 'M,': [992, 995, 1000, 1004, 1105, 1192, 1200, 1289, 1342, 1387, 1449, 1455, 1558, 1618, 1654, 1831, 1873, 1920, 1924, 1969, 2025, 2029, 2084, 2187], 'van': [993, 996, 1408, 1661, 1978], 'Son': [994], 'Rossum': [997], 'P,': [998, 1241, 1512, 1678, 1758, 1766, 1881, 2094, 2146, 2189], 'Connor': [999], 'Hosking-Jervis': [1001], 'F,': [1002, 1251, 1606, 2035], 'Tanaka': [1003], 'Reddy': [1005], 'Bass': [1007], 'E,': [1008, 1014, 1146, 1239, 1451, 1716, 1770, 2138], 'Powell': [1009], 'L,': [1010, 1077, 1383, 1560, 1926], 'Ahmad': [1011], 'S,': [1012, 1016, 1028, 1030, 1070, 1075, 1099, 1144, 1346, 1393, 1407, 1510, 1516, 1620, 1658, 1660, 1720, 1724, 1762, 1817, 1827, 1914, 1971, 2019, 2090, 2100], 'Pegers': [1013], 'Joshi': [1015], 'Sri': [1017], 'Wong': [1019], 'K,': [1020, 1616, 1922, 2037, 2092], 'Tam': [1021], 'H,': [1022, 1026, 1198, 1614, 1666, 1756, 1835, 1967, 2039, 2102, 2140], 'Hrouda': [1023], 'Qazi': [1025], 'Gordon': [1027], 'McCracken': [1029], 'Winkler': [1031, 1104], 'M': [1032, 1107, 1204, 1413, 1575, 1622, 1683, 1837, 1885, 1984, 2104, 2155, 2196], 'H': [1035, 1110, 1207, 1416, 1471, 1572, 1680, 1888, 2193], '(2020)': [1036, 1208], 'Comparison': [1038, 1112], 'Detection': [1042, 1159, 1321, 1936, 2000, 2123, 2165], 'between': [1043], 'Visual': [1044, 1424], 'Estimation': [1045, 1425], '(Cognitive': [1046], 'Registration)': [1047, 1052], 'Fusion': [1050, 1173, 1266, 1308, 1428, 1487, 1860, 1946, 2120], '(Software': [1051], 'Targeted': [1053, 1310, 1421, 1854, 1990], 'BiopsyJournal': [1056, 1267, 1949], 'Urology,': [1058, 1134, 1180, 1227, 1269, 1328, 1373, 1439, 1548, 1594, 1644, 1706, 1746, 1803, 1863, 1900, 1951, 2007, 2072, 2128, 2175, 2218], 'VOL.': [1059, 1135, 1181, 1228, 1270, 1329, 1374, 1440, 1499, 1549, 1595, 1645, 1707, 1747, 1804, 1864, 1901, 1952, 2008, 2073, 2129, 2176, 2219], '205,': [1060], 'NO.': [1061, 1137, 1183, 1230, 1272, 1331, 1376, 1442, 1501, 1551, 1597, 1647, 1709, 1749, 1806, 1866, 1903, 1954, 2010, 2075, 2131, 2178, 2221], '4,': [1062, 1184, 1807, 1904, 2132], '(1075-1081),': [1063], 'Online': [1064, 1140, 1186, 1233, 1275, 1334, 1379, 1445, 1504, 1554, 1602, 1650, 1712, 1752, 1809, 1869, 1906, 1957, 2013, 2078, 2134, 2181, 2224], 'publication': [1065, 1141, 1187, 1234, 1276, 1335, 1380, 1446, 1505, 1555, 1603, 1651, 1713, 1753, 1810, 1870, 1907, 1958, 2014, 2079, 2135, 2182, 2225], 'date:': [1066, 1142, 1188, 1235, 1277, 1336, 1381, 1447, 1506, 1556, 1604, 1652, 1714, 1754, 1811, 1871, 1908, 1959, 2015, 2080, 2136, 2183, 2226], '1-Apr-2021.Lovegrove': [1067], 'Miah': [1069], 'El-Shater': [1071], 'Bosaily': [1072], 'A,': [1073, 1083, 1085, 1091, 1148, 1190, 1194, 1196, 1243, 1279, 1385, 1395, 1465, 1508, 1562, 1570, 1668, 1670, 1877, 1910, 1918, 1973, 1977], 'Bott': [1074, 1657], 'Brown': [1076], 'Burns-Cox': [1078], 'N,': [1079, 1237, 1287, 1403, 1564, 1568, 2017], 'Dudderidge': [1080], 'T,': [1081, 1202, 1293, 1389, 1463, 1815, 1825, 2027, 2082, 2088], 'Henderson': [1084], 'Hindley': [1086, 1673], 'R,': [1087, 1089, 1093, 1097, 1249, 1518, 1674, 1963], 'Kaplan': [1088], 'Kirkham': [1090, 1976], 'Oldroyd': [1092], 'Parker': [1094], 'Persad': [1096], 'Punwani': [1098, 1406], 'Rosario': [1100], 'Shergill': [1102], 'I,': [1103, 1566, 1764, 1821], '(2019)': [1111, 1156], 'Transrectal': [1114, 1356, 2116], 'Ultrasound': [1115, 1486, 1945, 2117], 'Biopsies': [1121], 'Stratified': [1122], 'Multiparametric': [1124, 1303, 1794, 2051], 'Magnetic': [1125, 1170, 1263, 1304, 1484, 1527, 1734, 1795, 1851, 1857, 1942, 1987, 2052, 2112], 'Resonance': [1126, 1171, 1264, 1305, 1528, 1735, 1796, 1852, 1858, 1943, 1988, 2053, 2113], 'Score': [1128], 'PROMIS': [1131], 'TrialJournal': [1132, 1437], '203,': [1136, 1182], '1,': [1138, 1502, 1600, 1867], '(100-107),': [1139], '1-Jan-2020.Zhou': [1143], 'Chang': [1145, 1238], 'Patankar': [1147], 'Huang': [1149, 1246, 1347, 1519, 1725], 'J,': [1150, 1247, 1411, 1457, 1459, 1469, 1520, 1608, 1664, 1718, 1726, 1813, 2031, 2086], 'Marks': [1151, 1252, 1524, 1730], 'L': [1152, 1253, 1525, 1731], 'Natarajan': [1154, 1255, 1509, 1719], 'S': [1155, 1256, 1776, 2043], 'Rate': [1160], 'Freehand': [1162], 'versus': [1163], '3-Dimensional': [1164], 'Imaging-Ultrasound': [1172, 1859], 'Device': [1174], 'Naïve': [1177], 'MenJournal': [1178], '(699-705),': [1185], '1-Apr-2020.Kanthabalan': [1189], 'Arya': [1191, 1386], 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