Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2002123602', 'doi': 'https://doi.org/10.1091/mbc.e12-04-0331', 'title': 'Sub1 associates with Spt5 and influences RNA polymerase II transcription elongation rate', 'display_name': 'Sub1 associates with Spt5 and influences RNA polymerase II transcription elongation rate', 'publication_year': 2012, 'publication_date': '2012-09-13', 'ids': {'openalex': 'https://openalex.org/W2002123602', 'doi': 'https://doi.org/10.1091/mbc.e12-04-0331', 'mag': '2002123602', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/22973055', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3484106'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1091/mbc.e12-04-0331', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S188085164', 'display_name': 'Molecular Biology of the Cell', 'issn_l': '1059-1524', 'issn': ['1059-1524', '1939-4586'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319721', 'host_organization_name': 'American Society for Cell Biology', 'host_organization_lineage': ['https://openalex.org/P4310319721'], 'host_organization_lineage_names': ['American Society for Cell Biology'], 'type': 'journal'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'https://doi.org/10.1091/mbc.e12-04-0331', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5073640052', 'display_name': 'Alicia García', 'orcid': 'https://orcid.org/0000-0003-0121-9437'}, 'institutions': [{'id': 'https://openalex.org/I4210154586', 'display_name': 'Instituto de Biología Funcional y Genómica', 'ror': 'https://ror.org/055cmx385', 'country_code': 'ES', 'type': 'facility', 'lineage': ['https://openalex.org/I134820265', 'https://openalex.org/I184999862', 'https://openalex.org/I4210154586']}, {'id': 'https://openalex.org/I134820265', 'display_name': 'Consejo Superior de Investigaciones Científicas', 'ror': 'https://ror.org/02gfc7t72', 'country_code': 'ES', 'type': 'government', 'lineage': ['https://openalex.org/I134820265']}, {'id': 'https://openalex.org/I184999862', 'display_name': 'Universidad de Salamanca', 'ror': 'https://ror.org/02f40zc51', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I184999862']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Alicia García', 'raw_affiliation_strings': ['Instituto de Biología Funcional y Genómica, Consejo Superior de Investigaciones Científicas/Universidad de Salamanca, 37007 Salamanca, Spain'], 'affiliations': [{'raw_affiliation_string': 'Instituto de Biología Funcional y Genómica, Consejo Superior de Investigaciones Científicas/Universidad de Salamanca, 37007 Salamanca, Spain', 'institution_ids': ['https://openalex.org/I4210154586', 'https://openalex.org/I134820265', 'https://openalex.org/I184999862']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5041623590', 'display_name': 'Alejandro Collin', 'orcid': 'https://orcid.org/0000-0003-3546-2865'}, 'institutions': [{'id': 'https://openalex.org/I4210154586', 'display_name': 'Instituto de Biología Funcional y Genómica', 'ror': 'https://ror.org/055cmx385', 'country_code': 'ES', 'type': 'facility', 'lineage': ['https://openalex.org/I134820265', 'https://openalex.org/I184999862', 'https://openalex.org/I4210154586']}, {'id': 'https://openalex.org/I134820265', 'display_name': 'Consejo Superior de Investigaciones Científicas', 'ror': 'https://ror.org/02gfc7t72', 'country_code': 'ES', 'type': 'government', 'lineage': ['https://openalex.org/I134820265']}, {'id': 'https://openalex.org/I184999862', 'display_name': 'Universidad de Salamanca', 'ror': 'https://ror.org/02f40zc51', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I184999862']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Alejandro Collin', 'raw_affiliation_strings': ['Instituto de Biología Funcional y Genómica, Consejo Superior de Investigaciones Científicas/Universidad de Salamanca, 37007 Salamanca, Spain'], 'affiliations': [{'raw_affiliation_string': 'Instituto de Biología Funcional y Genómica, Consejo Superior de Investigaciones Científicas/Universidad de Salamanca, 37007 Salamanca, Spain', 'institution_ids': ['https://openalex.org/I4210154586', 'https://openalex.org/I134820265', 'https://openalex.org/I184999862']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5068426332', 'display_name': 'Olga Calvo', 'orcid': 'https://orcid.org/0000-0002-9786-7916'}, 'institutions': [{'id': 'https://openalex.org/I4210154586', 'display_name': 'Instituto de Biología Funcional y Genómica', 'ror': 'https://ror.org/055cmx385', 'country_code': 'ES', 'type': 'facility', 'lineage': ['https://openalex.org/I134820265', 'https://openalex.org/I184999862', 'https://openalex.org/I4210154586']}, {'id': 'https://openalex.org/I134820265', 'display_name': 'Consejo Superior de Investigaciones Científicas', 'ror': 'https://ror.org/02gfc7t72', 'country_code': 'ES', 'type': 'government', 'lineage': ['https://openalex.org/I134820265']}, {'id': 'https://openalex.org/I184999862', 'display_name': 'Universidad de Salamanca', 'ror': 'https://ror.org/02f40zc51', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I184999862']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Olga Calvo', 'raw_affiliation_strings': ['Instituto de Biología Funcional y Genómica, Consejo Superior de Investigaciones Científicas/Universidad de Salamanca, 37007 Salamanca, Spain'], 'affiliations': [{'raw_affiliation_string': 'Instituto de Biología Funcional y Genómica, Consejo Superior de Investigaciones Científicas/Universidad de Salamanca, 37007 Salamanca, Spain', 'institution_ids': ['https://openalex.org/I4210154586', 'https://openalex.org/I134820265', 'https://openalex.org/I184999862']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.892, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 26, 'citation_normalized_percentile': {'value': 0.893545, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 91, 'max': 92}, 'biblio': {'volume': '23', 'issue': '21', 'first_page': '4297', 'last_page': '4312'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10604', 'display_name': 'RNA Research and Splicing', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10604', 'display_name': 'RNA Research and Splicing', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10222', 'display_name': 'Genomics and Chromatin Dynamics', 'score': 0.998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10497', 'display_name': 'Fungal and yeast genetics research', 'score': 0.9974, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/rna-polymerase-ii', 'display_name': 'RNA polymerase II', 'score': 0.89491284}, {'id': 'https://openalex.org/keywords/transcription-preinitiation-complex', 'display_name': 'Transcription preinitiation complex', 'score': 0.6820708}, {'id': 'https://openalex.org/keywords/general-transcription-factor', 'display_name': 'General transcription factor', 'score': 0.60187554}, {'id': 'https://openalex.org/keywords/transcription', 'display_name': 'Transcription', 'score': 0.5451779}], 'concepts': [{'id': 'https://openalex.org/C64350747', 'wikidata': 'https://www.wikidata.org/wiki/Q15334993', 'display_name': 'RNA polymerase II', 'level': 5, 'score': 0.89491284}, {'id': 'https://openalex.org/C156951783', 'wikidata': 'https://www.wikidata.org/wiki/Q21110793', 'display_name': 'Transcription factor II E', 'level': 5, 'score': 0.81995696}, {'id': 'https://openalex.org/C154816499', 'wikidata': 'https://www.wikidata.org/wiki/Q21120535', 'display_name': 'Transcription factor II F', 'level': 5, 'score': 0.81063354}, {'id': 'https://openalex.org/C196117886', 'wikidata': 'https://www.wikidata.org/wiki/Q21110340', 'display_name': 'RNA polymerase II holoenzyme', 'level': 5, 'score': 0.7848754}, {'id': 'https://openalex.org/C172768829', 'wikidata': 'https://www.wikidata.org/wiki/Q14817959', 'display_name': 'Transcription factor II D', 'level': 5, 'score': 0.76779616}, {'id': 'https://openalex.org/C188740287', 'wikidata': 'https://www.wikidata.org/wiki/Q423333', 'display_name': 'Transcription preinitiation complex', 'level': 5, 'score': 0.6820708}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.667118}, {'id': 'https://openalex.org/C144825837', 'wikidata': 'https://www.wikidata.org/wiki/Q2316030', 'display_name': 'General transcription factor', 'level': 5, 'score': 0.60187554}, {'id': 'https://openalex.org/C179926584', 'wikidata': 'https://www.wikidata.org/wiki/Q207714', 'display_name': 'Transcription (linguistics)', 'level': 2, 'score': 0.5451779}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.5002928}, {'id': 'https://openalex.org/C77445288', 'wikidata': 'https://www.wikidata.org/wiki/Q637488', 'display_name': 'Coactivator', 'level': 4, 'score': 0.44453675}, {'id': 'https://openalex.org/C105208137', 'wikidata': 'https://www.wikidata.org/wiki/Q425812', 'display_name': 'Transcription factor II B', 'level': 5, 'score': 0.44146582}, {'id': 'https://openalex.org/C101762097', 'wikidata': 'https://www.wikidata.org/wiki/Q224093', 'display_name': 'Promoter', 'level': 4, 'score': 0.37224865}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.3693142}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.35326236}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.30534345}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.28701508}, {'id': 'https://openalex.org/C27153228', 'wikidata': 'https://www.wikidata.org/wiki/Q3787274', 'display_name': 'Transcriptional regulation', 'level': 4, 'score': 0.2611997}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.19770667}, {'id': 'https://openalex.org/C41895202', 'wikidata': 'https://www.wikidata.org/wiki/Q8162', 'display_name': 'Linguistics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C138885662', 'wikidata': 'https://www.wikidata.org/wiki/Q5891', 'display_name': 'Philosophy', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D002868', 'descriptor_name': 'Chromosomal Proteins, Non-Histone', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D012319', 'descriptor_name': 'RNA Polymerase II', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D012441', 'descriptor_name': 'Saccharomyces cerevisiae', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D012441', 'descriptor_name': 'Saccharomyces cerevisiae', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D029701', 'descriptor_name': 'Saccharomyces cerevisiae Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D061805', 'descriptor_name': 'Transcription Elongation, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D014157', 'descriptor_name': 'Transcription Factors', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D035602', 'descriptor_name': 'Transcriptional Elongation Factors', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D002843', 'descriptor_name': 'Chromatin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002843', 'descriptor_name': 'Chromatin', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002868', 'descriptor_name': 'Chromosomal Proteins, Non-Histone', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002868', 'descriptor_name': 'Chromosomal Proteins, Non-Histone', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004268', 'descriptor_name': 'DNA-Binding Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D017353', 'descriptor_name': 'Gene Deletion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015966', 'descriptor_name': 'Gene Expression Regulation, Fungal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016366', 'descriptor_name': 'Open Reading Frames', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016366', 'descriptor_name': 'Open Reading Frames', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D010766', 'descriptor_name': 'Phosphorylation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011485', 'descriptor_name': 'Protein Binding', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D011485', 'descriptor_name': 'Protein Binding', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012319', 'descriptor_name': 'RNA Polymerase II', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012326', 'descriptor_name': 'RNA Splicing', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D012326', 'descriptor_name': 'RNA Splicing', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012333', 'descriptor_name': 'RNA, Messenger', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D012333', 'descriptor_name': 'RNA, Messenger', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D012333', 'descriptor_name': 'RNA, Messenger', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012441', 'descriptor_name': 'Saccharomyces cerevisiae', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D029701', 'descriptor_name': 'Saccharomyces cerevisiae Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D029701', 'descriptor_name': 'Saccharomyces cerevisiae Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014157', 'descriptor_name': 'Transcription Factors', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D014157', 'descriptor_name': 'Transcription Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D035602', 'descriptor_name': 'Transcriptional Elongation Factors', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D035602', 'descriptor_name': 'Transcriptional Elongation Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 5, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1091/mbc.e12-04-0331', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S188085164', 'display_name': 'Molecular Biology of the Cell', 'issn_l': '1059-1524', 'issn': ['1059-1524', '1939-4586'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319721', 'host_organization_name': 'American Society for Cell Biology', 'host_organization_lineage': ['https://openalex.org/P4310319721'], 'host_organization_lineage_names': ['American Society for Cell Biology'], 'type': 'journal'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3484106', 'pdf_url': 'https://europepmc.org/articles/pmc3484106?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://hdl.handle.net/10261/67491', 'pdf_url': 'https://digital.csic.es/bitstream/10261/67491/1/Sub1%20associates.pdf', 'source': {'id': 'https://openalex.org/S4306400616', 'display_name': 'DIGITAL.CSIC (Spanish National Research Council (CSIC))', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I134820265', 'host_organization_name': 'Consejo Superior de Investigaciones Científicas', 'host_organization_lineage': ['https://openalex.org/I134820265'], 'host_organization_lineage_names': ['Consejo Superior de Investigaciones Científicas'], 'type': 'repository'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484106', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/22973055', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1091/mbc.e12-04-0331', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S188085164', 'display_name': 'Molecular Biology of the Cell', 'issn_l': '1059-1524', 'issn': ['1059-1524', '1939-4586'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319721', 'host_organization_name': 'American Society for Cell Biology', 'host_organization_lineage': ['https://openalex.org/P4310319721'], 'host_organization_lineage_names': ['American Society for Cell Biology'], 'type': 'journal'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 82, 'referenced_works': ['https://openalex.org/W147471776', 'https://openalex.org/W1485947996', 'https://openalex.org/W1526043578', 'https://openalex.org/W1760846735', 'https://openalex.org/W1899174876', 'https://openalex.org/W1967522002', 'https://openalex.org/W1969332827', 'https://openalex.org/W1972091887', 'https://openalex.org/W1973382421', 'https://openalex.org/W1973498182', 'https://openalex.org/W1973697733', 'https://openalex.org/W1974697229', 'https://openalex.org/W1979198416', 'https://openalex.org/W1981735048', 'https://openalex.org/W1989849863', 'https://openalex.org/W1990875360', 'https://openalex.org/W1994732022', 'https://openalex.org/W1994886301', 'https://openalex.org/W2006373999', 'https://openalex.org/W2008461545', 'https://openalex.org/W2010727636', 'https://openalex.org/W2013535834', 'https://openalex.org/W2013666169', 'https://openalex.org/W2015557667', 'https://openalex.org/W2021431933', 'https://openalex.org/W2022936085', 'https://openalex.org/W2025054326', 'https://openalex.org/W2025485946', 'https://openalex.org/W2031189364', 'https://openalex.org/W2032742580', 'https://openalex.org/W2033244618', 'https://openalex.org/W2036244319', 'https://openalex.org/W2044313365', 'https://openalex.org/W2062630554', 'https://openalex.org/W2067438466', 'https://openalex.org/W2069555162', 'https://openalex.org/W2071177849', 'https://openalex.org/W2073350644', 'https://openalex.org/W2073772594', 'https://openalex.org/W2076478546', 'https://openalex.org/W2079493448', 'https://openalex.org/W2080057367', 'https://openalex.org/W2081322742', 'https://openalex.org/W2082286024', 'https://openalex.org/W2091563313', 'https://openalex.org/W2095881318', 'https://openalex.org/W2097621806', 'https://openalex.org/W2099034328', 'https://openalex.org/W2100313737', 'https://openalex.org/W2100649212', 'https://openalex.org/W2102678326', 'https://openalex.org/W2102691305', 'https://openalex.org/W2104531065', 'https://openalex.org/W2105721989', 'https://openalex.org/W2108259296', 'https://openalex.org/W2110501180', 'https://openalex.org/W2110524124', 'https://openalex.org/W2117348845', 'https://openalex.org/W2126233054', 'https://openalex.org/W2130619792', 'https://openalex.org/W2131997929', 'https://openalex.org/W2132201134', 'https://openalex.org/W2134166862', 'https://openalex.org/W2135869142', 'https://openalex.org/W2138461551', 'https://openalex.org/W2139548742', 'https://openalex.org/W2139756153', 'https://openalex.org/W2143395788', 'https://openalex.org/W2146728788', 'https://openalex.org/W2148917483', 'https://openalex.org/W2151683280', 'https://openalex.org/W2152927202', 'https://openalex.org/W2153154881', 'https://openalex.org/W2156566553', 'https://openalex.org/W2159725870', 'https://openalex.org/W2160720092', 'https://openalex.org/W2166829841', 'https://openalex.org/W2167023949', 'https://openalex.org/W2169482535', 'https://openalex.org/W2170092320', 'https://openalex.org/W257400002', 'https://openalex.org/W2801944549'], 'related_works': ['https://openalex.org/W812958809', 'https://openalex.org/W4388253090', 'https://openalex.org/W2344189114', 'https://openalex.org/W2157087271', 'https://openalex.org/W2133503490', 'https://openalex.org/W2039675129', 'https://openalex.org/W2026537834', 'https://openalex.org/W2005097302', 'https://openalex.org/W2004796688', 'https://openalex.org/W1972091887'], 'abstract_inverted_index': {'The': [0], 'transcriptional': [1], 'coactivator': [2], 'Sub1': [3, 27, 56, 84, 103, 121, 133, 157], 'has': [4, 38], 'been': [5, 39], 'implicated': [6], 'in': [7, 13, 61, 107, 147], 'several': [8], 'steps': [9], 'of': [10, 19, 47, 88, 92, 137], 'mRNA': [11], 'metabolism': [12], 'yeast,': [14], 'such': [15], 'as': [16], 'the': [17, 48, 76, 79, 89, 97, 108], 'activation': [18], 'transcription,': [20], 'termination,': [21], 'and': [22, 34, 100, 104, 128, 139, 142, 161, 166], "3'-end": [23], 'formation.': [24], 'In': [25, 125], 'addition,': [26, 126], 'globally': [28], 'regulates': [29], 'RNA': [30, 65], 'polymerase': [31, 66], 'II': [32, 67], 'phosphorylation,': [33], 'most': [35], 'recently': [36], 'it': [37, 42], 'shown': [40], 'that': [41, 55, 71, 83, 101, 120, 132, 156], 'is': [43], 'a': [44, 58, 148], 'functional': [45], 'component': [46], 'preinitiation': [49], 'complex.': [50], 'Here': [51], 'we': [52], 'present': [53], 'evidence': [54], 'plays': [57], 'significant': [59], 'role': [60], 'transcription': [62, 114, 135, 168], 'elongation': [63, 80, 136, 169], 'by': [64, 96], '(RNAPII).': [68], 'We': [69], 'show': [70, 131], 'SUB1': [72], 'genetically': [73], 'interacts': [74], 'with': [75, 144, 159], 'gene': [77], 'encoding': [78], 'factor': [81], 'Spt5,': [82], 'influences': [85, 122, 134, 162], 'Spt5': [86, 105, 160], 'phosphorylation': [87], 'carboxy-terminal': [90], 'domain': [91], 'RNAPII': [93], 'largest': [94], 'subunit': [95], 'kinase': [98], 'Bur1,': [99], 'both': [102], 'copurify': [106], 'same': [109], 'complex,': [110], 'likely': [111], 'during': [112], 'early': [113], 'elongation.': [115], 'Indeed,': [116], 'our': [117, 153], 'data': [118, 130], 'indicate': [119, 155], 'Spt5-Rpb1': [123, 163], 'interaction.': [124], 'biochemical': [127], 'molecular': [129], 'constitutive': [138], 'inducible': [140], 'genes': [141], 'associates': [143, 158], 'coding': [145], 'regions': [146], 'transcription-dependent': [149], 'manner.': [150], 'Taken': [151], 'together,': [152], 'results': [154], 'complex': [164], 'levels': [165], 'consequently': [167], 'rate.': [170]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2002123602', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 4}, {'year': 2015, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 1}], 'updated_date': '2025-01-10T18:07:14.110733', 'created_date': '2016-06-24'}