Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2001481098', 'doi': 'https://doi.org/10.1111/j.2042-7158.1997.tb06087.x', 'title': 'Potential Efficacy of a Delta 5-Aminolevulinic Acid Bioadhesive Gel Formulation for the Photodynamic Treatment of Lesions of the Gastrointestinal Tract in Mice', 'display_name': 'Potential Efficacy of a Delta 5-Aminolevulinic Acid Bioadhesive Gel Formulation for the Photodynamic Treatment of Lesions of the Gastrointestinal Tract in Mice', 'publication_year': 1997, 'publication_date': '1997-07-01', 'ids': {'openalex': 'https://openalex.org/W2001481098', 'doi': 'https://doi.org/10.1111/j.2042-7158.1997.tb06087.x', 'mag': '2001481098', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/9255706'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.2042-7158.1997.tb06087.x', 'pdf_url': 'https://academic.oup.com/jpp/article-pdf/49/7/652/37020096/j.2042-7158.1997.tb06087.x.pdf', 'source': {'id': 'https://openalex.org/S118304455', 'display_name': 'Journal of Pharmacy and Pharmacology', 'issn_l': '0022-3573', 'issn': ['0022-3573', '2042-7158'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://academic.oup.com/jpp/article-pdf/49/7/652/37020096/j.2042-7158.1997.tb06087.x.pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5080945920', 'display_name': 'Véronique Vonarx', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210158411', 'display_name': 'Hôpital Laennec', 'ror': 'https://ror.org/04ckvpk15', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210158411']}, {'id': 'https://openalex.org/I4210115034', 'display_name': 'Hôpital Nord', 'ror': 'https://ror.org/029a4pp87', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210087487', 'https://openalex.org/I4210115034']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'V Vonarx', 'raw_affiliation_strings': ['Département Laser, Hôpital Nord Laennec, 44035 Nantes'], 'affiliations': [{'raw_affiliation_string': 'Département Laser, Hôpital Nord Laennec, 44035 Nantes', 'institution_ids': ['https://openalex.org/I4210158411', 'https://openalex.org/I4210115034']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5080633387', 'display_name': 'Sabine Eléouet', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210158411', 'display_name': 'Hôpital Laennec', 'ror': 'https://ror.org/04ckvpk15', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210158411']}, {'id': 'https://openalex.org/I4210115034', 'display_name': 'Hôpital Nord', 'ror': 'https://ror.org/029a4pp87', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210087487', 'https://openalex.org/I4210115034']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'S Eleouet', 'raw_affiliation_strings': ['Département Laser, Hôpital Nord Laennec, 44035 Nantes'], 'affiliations': [{'raw_affiliation_string': 'Département Laser, Hôpital Nord Laennec, 44035 Nantes', 'institution_ids': ['https://openalex.org/I4210158411', 'https://openalex.org/I4210115034']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5030364568', 'display_name': 'Jérôme Carré', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210115034', 'display_name': 'Hôpital Nord', 'ror': 'https://ror.org/029a4pp87', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210087487', 'https://openalex.org/I4210115034']}, {'id': 'https://openalex.org/I4210158411', 'display_name': 'Hôpital Laennec', 'ror': 'https://ror.org/04ckvpk15', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210158411']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'J Carre', 'raw_affiliation_strings': ['Département Laser, Hôpital Nord Laennec, 44035 Nantes'], 'affiliations': [{'raw_affiliation_string': 'Département Laser, Hôpital Nord Laennec, 44035 Nantes', 'institution_ids': ['https://openalex.org/I4210115034', 'https://openalex.org/I4210158411']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5074906727', 'display_name': 'P Ioss', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210158411', 'display_name': 'Hôpital Laennec', 'ror': 'https://ror.org/04ckvpk15', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210158411']}, {'id': 'https://openalex.org/I4210115034', 'display_name': 'Hôpital Nord', 'ror': 'https://ror.org/029a4pp87', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210087487', 'https://openalex.org/I4210115034']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'P Ioss', 'raw_affiliation_strings': ['Département Laser, Hôpital Nord Laennec, 44035 Nantes'], 'affiliations': [{'raw_affiliation_string': 'Département Laser, Hôpital Nord Laennec, 44035 Nantes', 'institution_ids': ['https://openalex.org/I4210158411', 'https://openalex.org/I4210115034']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5064212359', 'display_name': 'Anne Gouyette', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210115034', 'display_name': 'Hôpital Nord', 'ror': 'https://ror.org/029a4pp87', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210087487', 'https://openalex.org/I4210115034']}, {'id': 'https://openalex.org/I4210158411', 'display_name': 'Hôpital Laennec', 'ror': 'https://ror.org/04ckvpk15', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210158411']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'A Gouyette', 'raw_affiliation_strings': ['Département Laser, Hôpital Nord Laennec, 44035 Nantes', 'Laboratoire de Pharmacie Galénique, Faculté de Pharmacie, 44035 Nantes, France'], 'affiliations': [{'raw_affiliation_string': 'Département Laser, Hôpital Nord Laennec, 44035 Nantes', 'institution_ids': ['https://openalex.org/I4210115034', 'https://openalex.org/I4210158411']}, {'raw_affiliation_string': 'Laboratoire de Pharmacie Galénique, Faculté de Pharmacie, 44035 Nantes, France', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5068516538', 'display_name': 'A M Leray', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210158411', 'display_name': 'Hôpital Laennec', 'ror': 'https://ror.org/04ckvpk15', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210158411']}, {'id': 'https://openalex.org/I4210115034', 'display_name': 'Hôpital Nord', 'ror': 'https://ror.org/029a4pp87', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210087487', 'https://openalex.org/I4210115034']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'A M Leray', 'raw_affiliation_strings': ['Département Laser, Hôpital Nord Laennec, 44035 Nantes', 'Laboratoire de Pharmacie Galénique, Faculté de Pharmacie, 44035 Nantes, France'], 'affiliations': [{'raw_affiliation_string': 'Laboratoire de Pharmacie Galénique, Faculté de Pharmacie, 44035 Nantes, France', 'institution_ids': []}, {'raw_affiliation_string': 'Département Laser, Hôpital Nord Laennec, 44035 Nantes', 'institution_ids': ['https://openalex.org/I4210158411', 'https://openalex.org/I4210115034']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5031581181', 'display_name': 'Christian Merle', 'orcid': 'https://orcid.org/0000-0001-8529-4316'}, 'institutions': [{'id': 'https://openalex.org/I4210158411', 'display_name': 'Hôpital Laennec', 'ror': 'https://ror.org/04ckvpk15', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210158411']}, {'id': 'https://openalex.org/I4210115034', 'display_name': 'Hôpital Nord', 'ror': 'https://ror.org/029a4pp87', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210087487', 'https://openalex.org/I4210115034']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'C Merle', 'raw_affiliation_strings': ['Département Laser, Hôpital Nord Laennec, 44035 Nantes', 'Laboratoire de Pharmacie Galénique, Faculté de Pharmacie, 44035 Nantes, France'], 'affiliations': [{'raw_affiliation_string': 'Laboratoire de Pharmacie Galénique, Faculté de Pharmacie, 44035 Nantes, France', 'institution_ids': []}, {'raw_affiliation_string': 'Département Laser, Hôpital Nord Laennec, 44035 Nantes', 'institution_ids': ['https://openalex.org/I4210158411', 'https://openalex.org/I4210115034']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5080218702', 'display_name': 'Y. Lajat', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210158411', 'display_name': 'Hôpital Laennec', 'ror': 'https://ror.org/04ckvpk15', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210158411']}, {'id': 'https://openalex.org/I4210115034', 'display_name': 'Hôpital Nord', 'ror': 'https://ror.org/029a4pp87', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210087487', 'https://openalex.org/I4210115034']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Y Lajat', 'raw_affiliation_strings': ['Département Laser, Hôpital Nord Laennec, 44035 Nantes'], 'affiliations': [{'raw_affiliation_string': 'Département Laser, Hôpital Nord Laennec, 44035 Nantes', 'institution_ids': ['https://openalex.org/I4210158411', 'https://openalex.org/I4210115034']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5111517278', 'display_name': 'T. Patrice', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210158411', 'display_name': 'Hôpital Laennec', 'ror': 'https://ror.org/04ckvpk15', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210158411']}, {'id': 'https://openalex.org/I4210115034', 'display_name': 'Hôpital Nord', 'ror': 'https://ror.org/029a4pp87', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210087487', 'https://openalex.org/I4210115034']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'T Patrice', 'raw_affiliation_strings': ['Département Laser, Hôpital Nord Laennec, 44035 Nantes'], 'affiliations': [{'raw_affiliation_string': 'Département Laser, Hôpital Nord Laennec, 44035 Nantes', 'institution_ids': ['https://openalex.org/I4210158411', 'https://openalex.org/I4210115034']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2665, 'currency': 'GBP', 'value_usd': 3268, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.646, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 17, 'citation_normalized_percentile': {'value': 0.735929, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 83, 'max': 84}, 'biblio': {'volume': '49', 'issue': '7', 'first_page': '652', 'last_page': '656'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10957', 'display_name': 'Photodynamic Therapy Research Studies', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10957', 'display_name': 'Photodynamic Therapy Research Studies', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10782', 'display_name': 'Nanoplatforms for cancer theranostics', 'score': 0.9975, 'subfield': {'id': 'https://openalex.org/subfields/2204', 'display_name': 'Biomedical Engineering'}, 'field': {'id': 'https://openalex.org/fields/22', 'display_name': 'Engineering'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10903', 'display_name': 'Porphyrin and Phthalocyanine Chemistry', 'score': 0.9971, 'subfield': {'id': 'https://openalex.org/subfields/2505', 'display_name': 'Materials Chemistry'}, 'field': {'id': 'https://openalex.org/fields/25', 'display_name': 'Materials Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/protoporphyrin-ix', 'display_name': 'Protoporphyrin IX', 'score': 0.8687283}], 'concepts': [{'id': 'https://openalex.org/C2776634624', 'wikidata': 'https://www.wikidata.org/wiki/Q4914690', 'display_name': 'Bioadhesive', 'level': 3, 'score': 0.9636039}, {'id': 'https://openalex.org/C2779671804', 'wikidata': 'https://www.wikidata.org/wiki/Q619815', 'display_name': 'Protoporphyrin IX', 'level': 3, 'score': 0.8687283}, {'id': 'https://openalex.org/C207001950', 'wikidata': 'https://www.wikidata.org/wiki/Q141124', 'display_name': 'In vivo', 'level': 2, 'score': 0.8556657}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.59825397}, {'id': 'https://openalex.org/C2781323092', 'wikidata': 'https://www.wikidata.org/wiki/Q1428072', 'display_name': 'Photodynamic therapy', 'level': 2, 'score': 0.5748976}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.55576444}, {'id': 'https://openalex.org/C91881484', 'wikidata': 'https://www.wikidata.org/wiki/Q191807', 'display_name': 'Fluorescence', 'level': 2, 'score': 0.53135425}, {'id': 'https://openalex.org/C2781469039', 'wikidata': 'https://www.wikidata.org/wiki/Q18388377', 'display_name': 'Photosensitizer', 'level': 2, 'score': 0.4462338}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.4051258}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.35917556}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.3226062}, {'id': 'https://openalex.org/C43617362', 'wikidata': 'https://www.wikidata.org/wiki/Q170050', 'display_name': 'Chromatography', 'level': 1, 'score': 0.32086766}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.27548802}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.16065487}, {'id': 'https://openalex.org/C521977710', 'wikidata': 'https://www.wikidata.org/wiki/Q81163', 'display_name': 'Polymer', 'level': 2, 'score': 0.10741532}, {'id': 'https://openalex.org/C75473681', 'wikidata': 'https://www.wikidata.org/wiki/Q188651', 'display_name': 'Photochemistry', 'level': 1, 'score': 0.071983576}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C150903083', 'wikidata': 'https://www.wikidata.org/wiki/Q7108', 'display_name': 'Biotechnology', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C62520636', 'wikidata': 'https://www.wikidata.org/wiki/Q944', 'display_name': 'Quantum mechanics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000622', 'descriptor_name': 'Aminolevulinic Acid', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D001471', 'descriptor_name': 'Barrett Esophagus', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D010778', 'descriptor_name': 'Photochemotherapy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D013274', 'descriptor_name': 'Stomach Neoplasms', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D014014', 'descriptor_name': 'Tissue Adhesives', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D000622', 'descriptor_name': 'Aminolevulinic Acid', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D000622', 'descriptor_name': 'Aminolevulinic Acid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000622', 'descriptor_name': 'Aminolevulinic Acid', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001471', 'descriptor_name': 'Barrett Esophagus', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D001471', 'descriptor_name': 'Barrett Esophagus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001672', 'descriptor_name': 'Biocompatible Materials', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001672', 'descriptor_name': 'Biocompatible Materials', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D001672', 'descriptor_name': 'Biocompatible Materials', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004195', 'descriptor_name': 'Disease Models, Animal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005336', 'descriptor_name': 'Fiber Optic Technology', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005704', 'descriptor_name': 'Gallbladder', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005704', 'descriptor_name': 'Gallbladder', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D005704', 'descriptor_name': 'Gallbladder', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D005753', 'descriptor_name': 'Gastric Mucosa', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005753', 'descriptor_name': 'Gastric Mucosa', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D005753', 'descriptor_name': 'Gastric Mucosa', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D005782', 'descriptor_name': 'Gels', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D066298', 'descriptor_name': 'In Vitro Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017319', 'descriptor_name': 'Photosensitizing Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017319', 'descriptor_name': 'Photosensitizing Agents', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011524', 'descriptor_name': 'Protoporphyrins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011524', 'descriptor_name': 'Protoporphyrins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013050', 'descriptor_name': 'Spectrometry, Fluorescence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013274', 'descriptor_name': 'Stomach Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013274', 'descriptor_name': 'Stomach Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D014014', 'descriptor_name': 'Tissue Adhesives', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014014', 'descriptor_name': 'Tissue Adhesives', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D014014', 'descriptor_name': 'Tissue Adhesives', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.2042-7158.1997.tb06087.x', 'pdf_url': 'https://academic.oup.com/jpp/article-pdf/49/7/652/37020096/j.2042-7158.1997.tb06087.x.pdf', 'source': {'id': 'https://openalex.org/S118304455', 'display_name': 'Journal of Pharmacy and Pharmacology', 'issn_l': '0022-3573', 'issn': ['0022-3573', '2042-7158'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9255706', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.2042-7158.1997.tb06087.x', 'pdf_url': 'https://academic.oup.com/jpp/article-pdf/49/7/652/37020096/j.2042-7158.1997.tb06087.x.pdf', 'source': {'id': 'https://openalex.org/S118304455', 'display_name': 'Journal of Pharmacy and Pharmacology', 'issn_l': '0022-3573', 'issn': ['0022-3573', '2042-7158'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 19, 'referenced_works': ['https://openalex.org/W1504186761', 'https://openalex.org/W1506108633', 'https://openalex.org/W1592732258', 'https://openalex.org/W1979668498', 'https://openalex.org/W1984815101', 'https://openalex.org/W1987479252', 'https://openalex.org/W2001115630', 'https://openalex.org/W2026891239', 'https://openalex.org/W2033853636', 'https://openalex.org/W2072823589', 'https://openalex.org/W2084174503', 'https://openalex.org/W2084576539', 'https://openalex.org/W2087804429', 'https://openalex.org/W2091897384', 'https://openalex.org/W2109966571', 'https://openalex.org/W2150240082', 'https://openalex.org/W2341799933', 'https://openalex.org/W2409395041', 'https://openalex.org/W4285719527'], 'related_works': ['https://openalex.org/W4247044552', 'https://openalex.org/W4242341064', 'https://openalex.org/W4234956294', 'https://openalex.org/W3158206585', 'https://openalex.org/W3029655042', 'https://openalex.org/W2753164976', 'https://openalex.org/W2361848027', 'https://openalex.org/W2256492013', 'https://openalex.org/W2158428798', 'https://openalex.org/W2110332934'], 'abstract_inverted_index': {'A': [0], 'delta': [1], '5-aminolevulinic': [2], 'acid': [3], '(ALA)': [4], 'bioadhesive': [5], 'gel': [6, 42, 90], 'has': [7], 'been': [8], 'developed': [9], 'and': [10, 35, 47, 56, 71, 101, 110, 132, 150], 'evaluated': [11], 'in': [12], 'an': [13, 114], 'in-vivo': [14, 105], 'mouse': [15], 'model': [16], 'for': [17, 77, 93, 166], 'photodynamic': [18], 'treatment': [19], 'of': [20, 41, 95, 154], 'gastric': [21, 67], 'cancer': [22], 'or': [23], "Barrett's": [24], 'oesophagus.': [25], 'Four': [26], 'gels': [27], 'were': [28, 73], 'tested:': [29], 'noveon': [30, 46], 'AA-1,': [31], 'keltrol': [32, 48], 'T,': [33], 'lutrol': [34, 55], 'blanose.': [36, 57], 'An': [37], 'initial': [38], 'in-vitro': [39], 'study': [40, 84], 'adhesion': [43, 149], 'showed': [44, 106], 'that': [45, 61, 107], 'had': [49, 113], 'longer': [50], 'polyethylene': [51], 'transit': [52], 'times': [53], 'than': [54], 'In-vivo': [58], 'assays': [59], 'indicated': [60], 'protoporphyrin': [62, 117], 'IX': [63, 118], 'was': [64, 80, 91, 125, 161], 'synthesized': [65], 'by': [66], 'mucosa': [68], 'when': [69], 'ALA-noveon': [70, 89], 'ALA-lutrol': [72], 'used': [74], '(preferable': [75], 'results': [76], 'noveon).': [78], 'Keltrol': [79], 'eliminated': [81], 'from': [82], 'the': [83, 96, 163], 'after': [85, 143], 'these': [86], 'investigations.': [87], 'Only': [88], 'retained': [92], 'studies': [94], 'relationship': [97], 'between': [98], 'ALA': [99, 108, 155, 168], 'dose': [100], 'fluorescence.': [102], 'Fluorescence': [103], 'measurements': [104], 'concentration': [109], 'application': [111, 137], 'time': [112], 'influence': [115], 'on': [116], 'synthesis.': [119], 'Maximum': [120], 'intensity': [121], '(2091': [122], 'counts': [123, 141], 's-1)': [124], 'found': [126], 'with': [127, 136], '2': [128], 'mg': [129], 'mL-1': [130], 'ALA,': [131], 'fluorescence': [133], 'intensities': [134], 'differed': [135], 'time,': [138], 'reaching': [139], '1805': [140], 's-1': [142], '240': [144], 'min.': [145], 'ALA-noveon,': [146], 'showing': [147], 'good': [148], 'enabling': [151], 'efficient': [152], 'diffusion': [153], 'at': [156], 'a': [157], 'pH': [158], '<': [159], '6,': [160], 'considered': [162], 'best': [164], 'formulation': [165], 'maintaining': [167], 'stability.': [169]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2001481098', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-14T05:13:08.559153', 'created_date': '2016-06-24'}