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179], 'colonize': [33], 'the': [34, 71, 104, 107, 130, 134, 143, 147, 184, 191, 225, 237], 'respiratory': [35], 'epithelium.': [36], 'Although': [37], 'this': [38, 43, 128], 'is': [39, 48, 166, 228], 'not': [40, 211], 'fully': [41], 'understood,': [42], 'primary': [44], 'stage': [45], 'infection': [47], 'believed': [49], 'part': [53], 'mediated': [54], 'by': [55], 'specific': [57], 'type': [58], 'adhesins,': [60], 'named': [61], 'trimeric': [62], 'autotransporter': [63], 'adhesins': [64], '(TAAs).': [65], 'These': [66], 'homotrimeric': [67], 'proteins': [68], 'exist': [69], 'on': [70], 'surface': [72], 'many': [74], 'Gram': [75], 'negative': [76], 'pathogens': [77], 'often': [79], 'mediate': [80], 'number': [82], 'critical': [84], 'functions,': [85], 'including': [86], 'biofilm': [87, 177], 'formation,': [88], 'serum': [89, 204], 'resistance': [90, 201], 'adherence': [92, 172], 'an': [94, 155], 'invasion': [95, 213], 'host': [97], 'cells.': [98, 219], 'We': [99], 'have': [100], 'previously': [101], 'identified': [102], 'genome': [105], 'epidemic': [108], 'clinical': [109], 'isolate': [110], 'B.': [111, 152, 240], 'cenocepacia': [112, 153], 'J2315,': [113], 'novel': [115], 'cluster': [116, 136], 'genes': [118], 'putatively': [119], 'encoding': [120], 'three': [121], 'TAAs': [122], '(BCAM0219,': [123], 'BCAM0223': [124, 150, 226], 'BCAM0224).': [126], 'study,': [129], 'genomic': [131], 'organization': [132], 'TAA': [135, 149], 'has': [137], 'been': [138], 'determined.': [139], 'To': [140], 'further': [141], 'address': [142], 'direct': [144], 'role': [145], 'putative': [148], 'pathogenicity,': [154], 'isogenic': [156], 'mutant': [157, 165, 193], 'was': [158], 'constructed': [159], 'via': [160], 'insertional': [161], 'inactivation.': [162], 'The': [163], 'BCAM0223::Tp': [164, 192], 'deficient': [167], 'hemagglutination,': [169], 'affected': [170], 'vitronectin': [174], 'formation': [178], 'showed': [180, 195], 'attenuated': [181], 'virulence': [182, 231], 'Galleria': [185], 'mellonella': [186], 'model': [187], 'infection.': [189], 'Moreover,': [190], 'also': [194], 'significant': [197], 'reduction': [198], 'its': [200], 'human': [203, 216], 'as': [205, 207], 'well': [206], 'adherence,': [209], 'but': [210], 'of,': [214], 'cultured': [215], 'bronchial': [217], 'epithelial': [218], 'Altogether': [220], 'these': [221], 'results': [222], 'demonstrate': [223], 'that': [224, 233], 'protein': [227], 'multifunctional': [230], 'factor': [232], 'may': [234], 'contribute': [235], 'pathogenicity': [238], 'cenocepacia.': [241]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2001263765', 'counts_by_year': [{'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 6}, {'year': 2015, 'cited_by_count': 5}, {'year': 2014, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 6}], 'updated_date': '2024-09-17T15:13:46.813980', 'created_date': '2016-06-24'}