Publication Information

{'id': 'https://openalex.org/W2000790287', 'doi': 'https://doi.org/10.1021/tx00009a001', 'title': 'Covalent bonding of the prosthetic heme to protein: a potential mechanism for the suicide inactivation or activation of hemoproteins', 'display_name': 'Covalent bonding of the prosthetic heme to protein: a potential mechanism for the suicide inactivation or activation of hemoproteins', 'publication_year': 1989, 'publication_date': '1989-05-01', 'ids': {'openalex': 'https://openalex.org/W2000790287', 'doi': 'https://doi.org/10.1021/tx00009a001', 'mag': '2000790287', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/2519716'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/tx00009a001', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S152840809', 'display_name': 'Chemical Research in Toxicology', 'issn_l': '0893-228X', 'issn': ['0893-228X', '1520-5010'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5111739734', 'display_name': 'Yoichi Osawa', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210106489', 'display_name': 'National Heart Lung and Blood Institute', 'ror': 'https://ror.org/012pb6c26', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210106489']}, {'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Yoichi Osawa', 'raw_affiliation_strings': ['Laboratory of Chemical Pharmacology National Heart, Lung, and Blood Institute National Institutes of Health Bethesda, Maryland, 20892'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Chemical Pharmacology National Heart, Lung, and Blood Institute National Institutes of Health Bethesda, Maryland, 20892', 'institution_ids': ['https://openalex.org/I4210106489', 'https://openalex.org/I1299303238']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5109358092', 'display_name': 'Lance R. Pohl', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Lance R. Pohl', 'raw_affiliation_strings': ['National Institutes of Health'], 'affiliations': [{'raw_affiliation_string': 'National Institutes of Health', 'institution_ids': ['https://openalex.org/I1299303238']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.432, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 79, 'citation_normalized_percentile': {'value': 0.756329, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '2', 'issue': '3', 'first_page': '131', 'last_page': '141'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12094', 'display_name': 'Hemoglobin structure and function', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12094', 'display_name': 'Hemoglobin structure and function', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10493', 'display_name': 'Ion channel regulation and function', 'score': 0.9982, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10301', 'display_name': 'Mitochondrial Function and Pathology', 'score': 0.994, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/hemeprotein', 'display_name': 'Hemeprotein', 'score': 0.8339135}, {'id': 'https://openalex.org/keywords/hemin', 'display_name': 'Hemin', 'score': 0.4724907}], 'concepts': [{'id': 'https://openalex.org/C2776217839', 'wikidata': 'https://www.wikidata.org/wiki/Q189621', 'display_name': 'Heme', 'level': 3, 'score': 0.92289114}, {'id': 'https://openalex.org/C2778063876', 'wikidata': 'https://www.wikidata.org/wiki/Q192642', 'display_name': 'Myoglobin', 'level': 2, 'score': 0.8877646}, {'id': 'https://openalex.org/C20705724', 'wikidata': 'https://www.wikidata.org/wiki/Q902628', 'display_name': 'Hemeprotein', 'level': 4, 'score': 0.8339135}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.8220347}, {'id': 'https://openalex.org/C108204754', 'wikidata': 'https://www.wikidata.org/wiki/Q353392', 'display_name': 'Adduct', 'level': 2, 'score': 0.622458}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.5834801}, {'id': 'https://openalex.org/C180577832', 'wikidata': 'https://www.wikidata.org/wiki/Q127920', 'display_name': 'Covalent bond', 'level': 2, 'score': 0.48912746}, {'id': 'https://openalex.org/C2777723881', 'wikidata': 'https://www.wikidata.org/wiki/Q107315604', 'display_name': 'Hemin', 'level': 4, 'score': 0.4724907}, {'id': 'https://openalex.org/C526171541', 'wikidata': 'https://www.wikidata.org/wiki/Q407693', 'display_name': 'Cytochrome P450', 'level': 3, 'score': 0.46220043}, {'id': 'https://openalex.org/C2780768313', 'wikidata': 'https://www.wikidata.org/wiki/Q408068', 'display_name': 'Cytochrome', 'level': 3, 'score': 0.45542923}, {'id': 'https://openalex.org/C533411734', 'wikidata': 'https://www.wikidata.org/wiki/Q171877', 'display_name': 'Hydrogen peroxide', 'level': 2, 'score': 0.45178446}, {'id': 'https://openalex.org/C197957613', 'wikidata': 'https://www.wikidata.org/wiki/Q407280', 'display_name': 'Cofactor', 'level': 3, 'score': 0.4270721}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.30296233}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.12981057}], 'mesh': [{'descriptor_ui': 'D006418', 'descriptor_name': 'Heme', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D006420', 'descriptor_name': 'Hemeproteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001711', 'descriptor_name': 'Biotransformation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006418', 'descriptor_name': 'Heme', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006420', 'descriptor_name': 'Hemeproteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006420', 'descriptor_name': 'Hemeproteins', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011485', 'descriptor_name': 'Protein Binding', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1021/tx00009a001', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S152840809', 'display_name': 'Chemical Research in Toxicology', 'issn_l': '0893-228X', 'issn': ['0893-228X', '1520-5010'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320006', 'host_organization_name': 'American Chemical Society', 'host_organization_lineage': ['https://openalex.org/P4310320006'], 'host_organization_lineage_names': ['American Chemical Society'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/2519716', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.73}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4388635417', 'https://openalex.org/W2952643234', 'https://openalex.org/W2466287610', 'https://openalex.org/W2465600400', 'https://openalex.org/W2108445615', 'https://openalex.org/W2055834016', 'https://openalex.org/W2020647158', 'https://openalex.org/W2015039549', 'https://openalex.org/W1996610300', 'https://openalex.org/W1522117607'], 'abstract_inverted_index': {'ADVERTISEMENT': [0], 'RETURN': [1], 'TO': [2], 'ISSUEPREVArticleNEXTCovalent': [3], 'bonding': [4], 'of': [5, 20, 60, 95, 121], 'the': [6, 15, 57, 88, 93, 122, 133, 146, 149, 154, 161, 167], 'prosthetic': [7], 'heme': [8], 'to': [9, 82, 87], 'protein:': [10], 'a': [11, 118, 125, 138], 'potential': [12], 'mechanism': [13], 'for': [14, 153], 'suicide': [16], 'inactivation': [17], 'or': [18], 'activation': [19], 'hemoproteinsYoichi': [21], 'Osawa': [22], 'and': [23, 70, 75, 104, 148, 165, 181, 183], 'Lance': [24], 'R.': [25], 'PohlCite': [26], 'this:': [27], 'Chem.': [28], 'Res.': [29], 'Toxicol.': [30], '1989,': [31], '2,': [32], '3,': [33], '131–141Publication': [34], 'Date': [35], '(Print):May': [36], '1,': [37], '1989Publication': [38], 'History': [39], 'Published': [40], 'online1': [41], 'May': [42, 46], '2002Published': [43], 'inissue': [44], '1': [45], '1989https://pubs.acs.org/doi/10.1021/tx00009a001https://doi.org/10.1021/tx00009a001research-articleACS': [47], 'PublicationsRequest': [48], 'reuse': [49], 'permissionsArticle': [50], 'Views239Altmetric-Citations71LEARN': [51], 'ABOUT': [52], 'THESE': [53], 'METRICSArticle': [54], 'Views': [55], 'are': [56, 79, 92], 'COUNTER-compliant': [58], 'sum': [59], 'full': [61], 'text': [62], 'article': [63, 127], 'downloads': [64], 'since': [65], 'November': [66], '2008': [67], '(both': [68], 'PDF': [69], 'HTML)': [71], 'across': [72], 'all': [73], 'institutions': [74], 'individuals.': [76], 'These': [77], 'metrics': [78], 'regularly': [80], 'updated': [81, 105], 'reflect': [83], 'usage': [84], 'leading': [85], 'up': [86], 'last': [89], 'few': [90], 'days.Citations': [91], 'number': [94], 'other': [96], 'articles': [97], 'citing': [98], 'this': [99], 'article,': [100], 'calculated': [101], 'by': [102], 'Crossref': [103, 111], 'daily.': [106], 'Find': [107, 157], 'more': [108, 158], 'information': [109, 159], 'about': [110, 145], 'citation': [112], 'counts.The': [113], 'Altmetric': [114, 162], 'Attention': [115, 163], 'Score': [116, 164], 'is': [117, 169], 'quantitative': [119], 'measure': [120], 'attention': [123], 'that': [124], 'research': [126], 'has': [128], 'received': [129], 'online.': [130], 'Clicking': [131], 'on': [132, 160], 'donut': [134], 'icon': [135], 'will': [136], 'load': [137], 'page': [139], 'at': [140], 'altmetric.com': [141], 'with': [142, 177], 'additional': [143], 'details': [144], 'score': [147, 168], 'social': [150], 'media': [151], 'presence': [152], 'given': [155], 'article.': [156], 'how': [166], 'calculated.': [170], 'Share': [171, 186], 'Add': [172], 'toView': [173], 'InAdd': [174], 'Full': [175], 'Text': [176], 'ReferenceAdd': [178], 'Description': [179], 'ExportRISCitationCitation': [180], 'abstractCitation': [182], 'referencesMore': [184], 'Options': [185], 'onFacebookTwitterWechatLinked': [187], 'InRedditEmail': [188], 'Other': [189], 'access': [190], 'optionsGet': [191], 'e-Alertsclose': [192], 'Get': [193], 'e-Alerts': [194]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2000790287', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-07T16:27:03.560201', 'created_date': '2016-06-24'}