Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2000725303', 'doi': 'https://doi.org/10.1016/j.bbamcr.2008.07.010', 'title': 'Chromatin structure influences the sensitivity of DNA to γ-radiation', 'display_name': 'Chromatin structure influences the sensitivity of DNA to γ-radiation', 'publication_year': 2008, 'publication_date': '2008-12-01', 'ids': {'openalex': 'https://openalex.org/W2000725303', 'doi': 'https://doi.org/10.1016/j.bbamcr.2008.07.010', 'mag': '2000725303', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/18706456'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.bbamcr.2008.07.010', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210226410', 'display_name': 'Biochimica et Biophysica Acta (BBA) - Molecular Cell Research', 'issn_l': '0167-4889', 'issn': ['0167-4889', '1879-2596'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5074771839', 'display_name': 'Martin Falk', 'orcid': 'https://orcid.org/0000-0002-9229-0468'}, 'institutions': [{'id': 'https://openalex.org/I202391551', 'display_name': 'Czech Academy of Sciences', 'ror': 'https://ror.org/053avzc18', 'country_code': 'CZ', 'type': 'government', 'lineage': ['https://openalex.org/I202391551']}, {'id': 'https://openalex.org/I4210089928', 'display_name': 'Czech Academy of Sciences, Institute of Biophysics', 'ror': 'https://ror.org/00angvn73', 'country_code': 'CZ', 'type': 'facility', 'lineage': ['https://openalex.org/I202391551', 'https://openalex.org/I4210089928']}], 'countries': ['CZ'], 'is_corresponding': False, 'raw_author_name': 'Martin Falk', 'raw_affiliation_strings': ['Institute of Biophysics, Academy of Sciences of the Czech Republic, Kralovopolska 135, 61265 Brno, Czech Republic'], 'affiliations': [{'raw_affiliation_string': 'Institute of Biophysics, Academy of Sciences of the Czech Republic, Kralovopolska 135, 61265 Brno, Czech Republic', 'institution_ids': ['https://openalex.org/I202391551', 'https://openalex.org/I4210089928']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5105191423', 'display_name': 'Emı́lie Lukášová', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I202391551', 'display_name': 'Czech Academy of Sciences', 'ror': 'https://ror.org/053avzc18', 'country_code': 'CZ', 'type': 'government', 'lineage': ['https://openalex.org/I202391551']}, {'id': 'https://openalex.org/I4210089928', 'display_name': 'Czech Academy of Sciences, Institute of Biophysics', 'ror': 'https://ror.org/00angvn73', 'country_code': 'CZ', 'type': 'facility', 'lineage': ['https://openalex.org/I202391551', 'https://openalex.org/I4210089928']}], 'countries': ['CZ'], 'is_corresponding': True, 'raw_author_name': 'Emilie Lukášová', 'raw_affiliation_strings': ['Institute of Biophysics, Academy of Sciences of the Czech Republic, Kralovopolska 135, 61265 Brno, Czech Republic'], 'affiliations': [{'raw_affiliation_string': 'Institute of Biophysics, Academy of Sciences of the Czech Republic, Kralovopolska 135, 61265 Brno, Czech Republic', 'institution_ids': ['https://openalex.org/I202391551', 'https://openalex.org/I4210089928']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5034705814', 'display_name': 'Stanislav Kozubek', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I202391551', 'display_name': 'Czech Academy of Sciences', 'ror': 'https://ror.org/053avzc18', 'country_code': 'CZ', 'type': 'government', 'lineage': ['https://openalex.org/I202391551']}, {'id': 'https://openalex.org/I4210089928', 'display_name': 'Czech Academy of Sciences, Institute of Biophysics', 'ror': 'https://ror.org/00angvn73', 'country_code': 'CZ', 'type': 'facility', 'lineage': ['https://openalex.org/I202391551', 'https://openalex.org/I4210089928']}], 'countries': ['CZ'], 'is_corresponding': False, 'raw_author_name': 'Stanislav Kozubek', 'raw_affiliation_strings': ['Institute of Biophysics, Academy of Sciences of the Czech Republic, Kralovopolska 135, 61265 Brno, Czech Republic'], 'affiliations': [{'raw_affiliation_string': 'Institute of Biophysics, Academy of Sciences of the Czech Republic, Kralovopolska 135, 61265 Brno, Czech Republic', 'institution_ids': ['https://openalex.org/I202391551', 'https://openalex.org/I4210089928']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5105191423'], 'corresponding_institution_ids': ['https://openalex.org/I202391551', 'https://openalex.org/I4210089928'], 'apc_list': {'value': 3380, 'currency': 'USD', 'value_usd': 3380, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 3.237, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 177, 'citation_normalized_percentile': {'value': 0.999983, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '1783', 'issue': '12', 'first_page': '2398', 'last_page': '2414'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10123', 'display_name': 'Molecular Mechanisms of DNA Damage Response', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10123', 'display_name': 'Molecular Mechanisms of DNA Damage Response', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10222', 'display_name': 'Regulation of Chromatin Structure and Function', 'score': 0.9992, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10432', 'display_name': 'G-Quadruplex DNA Structures and Functions', 'score': 0.9976, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/chia-pet', 'display_name': 'ChIA-PET', 'score': 0.5915152}, {'id': 'https://openalex.org/keywords/dna-damage', 'display_name': 'DNA Damage', 'score': 0.571378}, {'id': 'https://openalex.org/keywords/dna-structure', 'display_name': 'DNA Structure', 'score': 0.569522}, {'id': 'https://openalex.org/keywords/scaffold/matrix-attachment-region', 'display_name': 'Scaffold/matrix attachment region', 'score': 0.55241686}, {'id': 'https://openalex.org/keywords/chromatin', 'display_name': 'Chromatin', 'score': 0.526592}, {'id': 'https://openalex.org/keywords/premature-chromosome-condensation', 'display_name': 'Premature chromosome condensation', 'score': 0.42347386}], 'concepts': [{'id': 'https://openalex.org/C83640560', 'wikidata': 'https://www.wikidata.org/wiki/Q180951', 'display_name': 'Chromatin', 'level': 3, 'score': 0.9484749}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.61059815}, {'id': 'https://openalex.org/C67258246', 'wikidata': 'https://www.wikidata.org/wiki/Q5065897', 'display_name': 'ChIA-PET', 'level': 5, 'score': 0.5915152}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.58351606}, {'id': 'https://openalex.org/C103435993', 'wikidata': 'https://www.wikidata.org/wiki/Q837783', 'display_name': 'Heterochromatin', 'level': 4, 'score': 0.556806}, {'id': 'https://openalex.org/C56262557', 'wikidata': 'https://www.wikidata.org/wiki/Q3931949', 'display_name': 'Scaffold/matrix attachment region', 'level': 5, 'score': 0.55241686}, {'id': 'https://openalex.org/C45413362', 'wikidata': 'https://www.wikidata.org/wiki/Q6013254', 'display_name': 'Prophase', 'level': 4, 'score': 0.544439}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.49136797}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.438618}, {'id': 'https://openalex.org/C143425029', 'wikidata': 'https://www.wikidata.org/wiki/Q5205747', 'display_name': 'DNA damage', 'level': 3, 'score': 0.4379782}, {'id': 'https://openalex.org/C30481170', 'wikidata': 'https://www.wikidata.org/wiki/Q37748', 'display_name': 'Chromosome', 'level': 3, 'score': 0.43575004}, {'id': 'https://openalex.org/C178108356', 'wikidata': 'https://www.wikidata.org/wiki/Q7240230', 'display_name': 'Premature chromosome condensation', 'level': 4, 'score': 0.42347386}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.41377902}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.35473055}, {'id': 'https://openalex.org/C167227067', 'wikidata': 'https://www.wikidata.org/wiki/Q5113739', 'display_name': 'Chromatin remodeling', 'level': 4, 'score': 0.3321657}, {'id': 'https://openalex.org/C148196450', 'wikidata': 'https://www.wikidata.org/wiki/Q21100485', 'display_name': 'Meiosis', 'level': 3, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D002843', 'descriptor_name': 'Chromatin', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': True}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': True}, {'descriptor_ui': 'D004249', 'descriptor_name': 'DNA Damage', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': True}, {'descriptor_ui': 'D005720', 'descriptor_name': 'Gamma Rays', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': False}, {'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002467', 'descriptor_name': 'Cell Nucleus', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002467', 'descriptor_name': 'Cell Nucleus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002843', 'descriptor_name': 'Chromatin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D047369', 'descriptor_name': 'Chromatin Immunoprecipitation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003037', 'descriptor_name': 'Cobalt Radioisotopes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004249', 'descriptor_name': 'DNA Damage', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004260', 'descriptor_name': 'DNA Repair', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': False}, {'descriptor_ui': 'D004260', 'descriptor_name': 'DNA Repair', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004791', 'descriptor_name': 'Enzyme Inhibitors', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D004791', 'descriptor_name': 'Enzyme Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005347', 'descriptor_name': 'Fibroblasts', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': False}, {'descriptor_ui': 'D005347', 'descriptor_name': 'Fibroblasts', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D005347', 'descriptor_name': 'Fibroblasts', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D005347', 'descriptor_name': 'Fibroblasts', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005455', 'descriptor_name': 'Fluorescent Antibody Technique', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016193', 'descriptor_name': 'G1 Phase', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': False}, {'descriptor_ui': 'D016193', 'descriptor_name': 'G1 Phase', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D016193', 'descriptor_name': 'G1 Phase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005786', 'descriptor_name': 'Gene Expression Regulation', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': False}, {'descriptor_ui': 'D005786', 'descriptor_name': 'Gene Expression Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D056572', 'descriptor_name': 'Histone Deacetylase Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006655', 'descriptor_name': 'Histone Deacetylases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006655', 'descriptor_name': 'Histone Deacetylases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006877', 'descriptor_name': 'Hydroxamic Acids', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D006877', 'descriptor_name': 'Hydroxamic Acids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017404', 'descriptor_name': 'In Situ Hybridization, Fluorescence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016196', 'descriptor_name': 'S Phase', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': False}, {'descriptor_ui': 'D016196', 'descriptor_name': 'S Phase', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D016196', 'descriptor_name': 'S Phase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012867', 'descriptor_name': 'Skin', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': False}, {'descriptor_ui': 'D012867', 'descriptor_name': 'Skin', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D012867', 'descriptor_name': 'Skin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012867', 'descriptor_name': 'Skin', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.bbamcr.2008.07.010', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210226410', 'display_name': 'Biochimica et Biophysica Acta (BBA) - Molecular Cell Research', 'issn_l': '0167-4889', 'issn': ['0167-4889', '1879-2596'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/18706456', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/1', 'display_name': 'No poverty', 'score': 0.76}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 58, 'referenced_works': ['https://openalex.org/W1481979447', 'https://openalex.org/W1483692899', 'https://openalex.org/W1509466986', 'https://openalex.org/W1603793127', 'https://openalex.org/W1975297840', 'https://openalex.org/W1981840277', 'https://openalex.org/W1984411935', 'https://openalex.org/W1985775217', 'https://openalex.org/W1987388787', 'https://openalex.org/W1988284872', 'https://openalex.org/W1995258838', 'https://openalex.org/W1996821738', 'https://openalex.org/W1997154923', 'https://openalex.org/W1997345448', 'https://openalex.org/W2002405288', 'https://openalex.org/W2012391942', 'https://openalex.org/W2012888776', 'https://openalex.org/W2022702976', 'https://openalex.org/W2022811243', 'https://openalex.org/W2026953150', 'https://openalex.org/W2030808618', 'https://openalex.org/W2031203839', 'https://openalex.org/W2033376776', 'https://openalex.org/W2039313637', 'https://openalex.org/W2039395294', 'https://openalex.org/W2047837922', 'https://openalex.org/W2049708436', 'https://openalex.org/W2051869287', 'https://openalex.org/W2052668971', 'https://openalex.org/W2060228572', 'https://openalex.org/W2061111901', 'https://openalex.org/W2061352751', 'https://openalex.org/W2068690942', 'https://openalex.org/W2074200686', 'https://openalex.org/W2074887011', 'https://openalex.org/W2077494070', 'https://openalex.org/W2083087496', 'https://openalex.org/W2089417788', 'https://openalex.org/W2089829464', 'https://openalex.org/W2091660221', 'https://openalex.org/W2093616732', 'https://openalex.org/W2094912385', 'https://openalex.org/W2100743187', 'https://openalex.org/W2102999073', 'https://openalex.org/W2104855205', 'https://openalex.org/W2106797333', 'https://openalex.org/W2108027073', 'https://openalex.org/W2111336486', 'https://openalex.org/W2114014715', 'https://openalex.org/W2121834970', 'https://openalex.org/W2128680272', 'https://openalex.org/W2140388293', 'https://openalex.org/W2148309758', 'https://openalex.org/W2154026141', 'https://openalex.org/W2162967758', 'https://openalex.org/W2163470930', 'https://openalex.org/W2280758135', 'https://openalex.org/W4317675606'], 'related_works': ['https://openalex.org/W4250257883', 'https://openalex.org/W2462931191', 'https://openalex.org/W2126878399', 'https://openalex.org/W2096065245', 'https://openalex.org/W2055121745', 'https://openalex.org/W2039247620', 'https://openalex.org/W2030504921', 'https://openalex.org/W2010649437', 'https://openalex.org/W1995962202', 'https://openalex.org/W1991790766'], 'abstract_inverted_index': {'For': [0], 'the': [1, 80, 123, 134, 142], 'first': [2], 'time,': [3], 'DNA': [4, 48, 121], 'double-strand': [5], 'breaks': [6], '(DSBs)': [7], 'were': [8], 'directly': [9], 'visualized': [10], 'in': [11, 66, 102, 107, 128, 170, 185, 193], 'functionally': [12], 'and': [13, 64, 79, 105, 154, 175, 188], 'structurally': [14], 'different': [15, 194], 'chromatin': [16, 28, 46, 70, 108, 136, 186], 'domains': [17], 'of': [18, 44, 75, 120, 144, 148, 180, 190], 'human': [19], 'cells.': [20], 'The': [21, 91], 'results': [22, 115, 160], 'show': [23, 161], 'that': [24, 116, 162], 'genetically': [25, 152], 'inactive': [26], 'condensed': [27], 'is': [29, 130], 'much': [30], 'less': [31], 'susceptible': [32], 'to': [33, 122, 151], 'DSB': [34, 55, 62, 191], 'induction': [35, 63], 'by': [36, 52, 125, 133, 141], 'γ-rays': [37], 'than': [38], 'expressed,': [39], 'decondensed': [40, 155], 'domains.': [41], 'Higher': [42], 'sensitivity': [43, 119], 'open': [45], 'for': [47, 167], 'damage': [49, 124], 'was': [50], 'accompanied': [51], 'more': [53], 'efficient': [54], 'repair.': [56], 'These': [57], 'findings': [58], 'follow': [59], 'from': [60, 95, 112], 'comparing': [61], 'repair': [65, 192], 'two': [67], '11': [68], 'Mbp-long': [69], 'regions,': [71], 'one': [72], 'with': [73, 97], 'clusters': [74], 'highly': [76], 'expressed': [77], 'genes': [78, 85], 'other,': [81], 'gene-poor,': [82], 'containing': [83], 'mainly': [84], 'having': [86], 'only': [87], 'low': [88], 'transcriptional': [89], 'activity.': [90], 'same': [92], 'conclusions': [93], 'result': [94], 'experiments': [96], 'whole': [98], 'chromosome': [99], 'territories,': [100], 'differing': [101], 'gene': [103], 'density': [104], 'consequently': [106], 'condensation.': [109], 'It': [110], 'follows': [111], 'our': [113, 159], 'further': [114], 'this': [117], 'lower': [118], 'ionizing': [126], 'radiation': [127], 'heterochromatin': [129], 'not': [131], 'caused': [132], 'simple': [135], 'condensation': [137], 'but': [138], 'very': [139], 'probably': [140], 'presence': [143], 'a': [145], 'higher': [146], 'amount': [147], 'proteins': [149], 'compared': [150], 'active': [153], 'chromatin.': [156], 'In': [157], 'addition,': [158], 'some': [163], 'agents': [164], 'potentially': [165], 'used': [166], 'cell': [168, 178], 'killing': [169], 'cancer': [171], 'therapy': [172], '(TSA,': [173], 'hypotonic': [174], 'hypertonic)': [176], 'influence': [177], 'survival': [179], 'irradiated': [181], 'cells': [182], 'via': [183], 'changes': [184], 'structure': [187], 'efficiency': [189], 'ways.': [195]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2000725303', 'counts_by_year': [{'year': 2024, 'cited_by_count': 7}, {'year': 2023, 'cited_by_count': 12}, {'year': 2022, 'cited_by_count': 10}, {'year': 2021, 'cited_by_count': 11}, {'year': 2020, 'cited_by_count': 15}, {'year': 2019, 'cited_by_count': 8}, {'year': 2018, 'cited_by_count': 7}, {'year': 2017, 'cited_by_count': 12}, {'year': 2016, 'cited_by_count': 15}, {'year': 2015, 'cited_by_count': 10}, {'year': 2014, 'cited_by_count': 15}, {'year': 2013, 'cited_by_count': 18}, {'year': 2012, 'cited_by_count': 12}], 'updated_date': '2024-09-16T16:16:44.525779', 'created_date': '2016-06-24'}