Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2000489536', 'doi': 'https://doi.org/10.1016/0014-5793(92)80925-7', 'title': 'Expression of functional <i>Thermoplasma acidophilum</i> proteasomes in <i>Escherichia coli</i>', 'display_name': 'Expression of functional <i>Thermoplasma acidophilum</i> proteasomes in <i>Escherichia coli</i>', 'publication_year': 1992, 'publication_date': '1992-11-09', 'ids': {'openalex': 'https://openalex.org/W2000489536', 'doi': 'https://doi.org/10.1016/0014-5793(92)80925-7', 'mag': '2000489536', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/1426246'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/0014-5793(92)80925-7', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S104830714', 'display_name': 'FEBS Letters', 'issn_l': '0014-5793', 'issn': ['0014-5793', '1873-3468'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5050695209', 'display_name': 'Peter Zwickl', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210150093', 'display_name': 'Max Planck Institute of Biochemistry', 'ror': 'https://ror.org/04py35477', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I149899117', 'https://openalex.org/I4210150093']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Peter Zwickl', 'raw_affiliation_strings': ['Max-Planck-Institute für Biochemie, Am Klopferspitz 18a, D-8033 Martinsried, Germany'], 'affiliations': [{'raw_affiliation_string': 'Max-Planck-Institute für Biochemie, Am Klopferspitz 18a, D-8033 Martinsried, Germany', 'institution_ids': ['https://openalex.org/I4210150093']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5041718533', 'display_name': 'Friedrich Lottspeich', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210150093', 'display_name': 'Max Planck Institute of Biochemistry', 'ror': 'https://ror.org/04py35477', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I149899117', 'https://openalex.org/I4210150093']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Friedrich Lottspeich', 'raw_affiliation_strings': ['Max-Planck-Institute für Biochemie, Am Klopferspitz 18a, D-8033 Martinsried, Germany'], 'affiliations': [{'raw_affiliation_string': 'Max-Planck-Institute für Biochemie, Am Klopferspitz 18a, D-8033 Martinsried, Germany', 'institution_ids': ['https://openalex.org/I4210150093']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5029559203', 'display_name': 'Wolfgang Baumeister', 'orcid': 'https://orcid.org/0000-0001-8154-8809'}, 'institutions': [{'id': 'https://openalex.org/I4210150093', 'display_name': 'Max Planck Institute of Biochemistry', 'ror': 'https://ror.org/04py35477', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I149899117', 'https://openalex.org/I4210150093']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Wolfgang Baumeister', 'raw_affiliation_strings': ['Max-Planck-Institute für Biochemie, Am Klopferspitz 18a, D-8033 Martinsried, Germany'], 'affiliations': [{'raw_affiliation_string': 'Max-Planck-Institute für Biochemie, Am Klopferspitz 18a, D-8033 Martinsried, Germany', 'institution_ids': ['https://openalex.org/I4210150093']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3610, 'currency': 'USD', 'value_usd': 3610, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 4.027, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 87, 'citation_normalized_percentile': {'value': 0.892648, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '312', 'issue': '2-3', 'first_page': '157', 'last_page': '160'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11041', 'display_name': 'Ubiquitin-Proteasome Proteolytic Pathway', 'score': 0.9799, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11041', 'display_name': 'Ubiquitin-Proteasome Proteolytic Pathway', 'score': 0.9799, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12505', 'display_name': 'Role of Fibroblast Activation in Cancer Progression', 'score': 0.9748, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10602', 'display_name': 'Glycosylation in Health and Disease', 'score': 0.9654, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/thermoplasma-acidophilum', 'display_name': 'Thermoplasma acidophilum', 'score': 0.9995202}, {'id': 'https://openalex.org/keywords/proteasome', 'display_name': 'Proteasome', 'score': 0.498743}], 'concepts': [{'id': 'https://openalex.org/C2779198424', 'wikidata': 'https://www.wikidata.org/wiki/Q14324411', 'display_name': 'Thermoplasma acidophilum', 'level': 3, 'score': 0.9995202}, {'id': 'https://openalex.org/C547475151', 'wikidata': 'https://www.wikidata.org/wiki/Q25419', 'display_name': 'Escherichia coli', 'level': 3, 'score': 0.7993243}, {'id': 'https://openalex.org/C27740335', 'wikidata': 'https://www.wikidata.org/wiki/Q14878333', 'display_name': 'Proteasome', 'level': 2, 'score': 0.6652848}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.599658}, {'id': 'https://openalex.org/C40767141', 'wikidata': 'https://www.wikidata.org/wiki/Q285697', 'display_name': 'Recombinant DNA', 'level': 3, 'score': 0.5838965}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.45981938}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.24656293}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.22226742}], 'mesh': [{'descriptor_ui': 'D003546', 'descriptor_name': 'Cysteine Endopeptidases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D009097', 'descriptor_name': 'Multienzyme Complexes', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D013822', 'descriptor_name': 'Thermoplasma', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000595', 'descriptor_name': 'Amino Acid Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001483', 'descriptor_name': 'Base Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015153', 'descriptor_name': 'Blotting, Western', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003001', 'descriptor_name': 'Cloning, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003546', 'descriptor_name': 'Cysteine Endopeptidases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D003546', 'descriptor_name': 'Cysteine Endopeptidases', 'qualifier_ui': 'Q000302', 'qualifier_name': 'isolation & purification', 'is_major_topic': False}, {'descriptor_ui': 'D003546', 'descriptor_name': 'Cysteine Endopeptidases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004269', 'descriptor_name': 'DNA, Bacterial', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015180', 'descriptor_name': 'Electrophoresis, Gel, Two-Dimensional', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004926', 'descriptor_name': 'Escherichia coli', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008854', 'descriptor_name': 'Microscopy, Electron', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009097', 'descriptor_name': 'Multienzyme Complexes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009097', 'descriptor_name': 'Multienzyme Complexes', 'qualifier_ui': 'Q000302', 'qualifier_name': 'isolation & purification', 'is_major_topic': False}, {'descriptor_ui': 'D009097', 'descriptor_name': 'Multienzyme Complexes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D046988', 'descriptor_name': 'Proteasome Endopeptidase Complex', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': 'Q000302', 'qualifier_name': 'isolation & purification', 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D011994', 'descriptor_name': 'Recombinant Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013822', 'descriptor_name': 'Thermoplasma', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D013822', 'descriptor_name': 'Thermoplasma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/0014-5793(92)80925-7', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S104830714', 'display_name': 'FEBS Letters', 'issn_l': '0014-5793', 'issn': ['0014-5793', '1873-3468'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/1426246', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 23, 'referenced_works': ['https://openalex.org/W1258228527', 'https://openalex.org/W1499894587', 'https://openalex.org/W1510053656', 'https://openalex.org/W1873199501', 'https://openalex.org/W1985728179', 'https://openalex.org/W1990148399', 'https://openalex.org/W1999741800', 'https://openalex.org/W2003642562', 'https://openalex.org/W2004180892', 'https://openalex.org/W2010955189', 'https://openalex.org/W2012259755', 'https://openalex.org/W2021769945', 'https://openalex.org/W2032689356', 'https://openalex.org/W2052015211', 'https://openalex.org/W2068518785', 'https://openalex.org/W2073515886', 'https://openalex.org/W2087441938', 'https://openalex.org/W2088191492', 'https://openalex.org/W2138270253', 'https://openalex.org/W2169319614', 'https://openalex.org/W2394803502', 'https://openalex.org/W2496774298', 'https://openalex.org/W263799869'], 'related_works': ['https://openalex.org/W6856752', 'https://openalex.org/W4213178320', 'https://openalex.org/W3046976449', 'https://openalex.org/W2941888903', 'https://openalex.org/W2917043960', 'https://openalex.org/W2916929354', 'https://openalex.org/W2068656520', 'https://openalex.org/W2015583980', 'https://openalex.org/W2009804616', 'https://openalex.org/W1595313680'], 'abstract_inverted_index': {'The': [0, 26], 'two': [1], 'genes': [2], 'encoding': [3], 'the': [4, 8], 'constituent': [5], 'subunits': [6], 'of': [7], 'Thermoplasma': [9], 'acidophilum': [10, 46], 'proteasome': [11], 'were': [12, 29], 'expressed': [13], 'in': [14], 'Escherichia': [15], 'coli': [16], 'yielding': [17], 'fully': [18], 'assembled': [19], 'molecules': [20], 'as': [21], 'shown': [22, 35], 'by': [23], 'electron': [24], 'microscopy.': [25], 'recombinant': [27], 'proteasomes': [28, 42], 'purified': [30], 'to': [31, 36], 'homogeneity': [32], 'and': [33], 'ware': [34], 'have': [37], 'proteolytic': [38], 'activity': [39], 'indistinguishable': [40], 'from': [41, 44], 'isolated': [43], 'T.': [45], '.': [47]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2000489536', 'counts_by_year': [{'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-08-15T05:13:28.957993', 'created_date': '2016-06-24'}