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'are': [46, 129, 195, 211, 218, 227], 'well': [48], 'understood.': [49], 'PFOA': [50, 62, 79, 90, 128, 237], 'has': [51], 'been': [52], 'used': [53], 'to': [54, 224, 229], 'manufacture': [55], 'such': [56], 'products': [57], 'as': [58], 'Gore-Tex': [59], 'and': [60, 106, 109, 118, 142, 200, 213, 223], 'Teflon.': [61], 'break': [65], 'down': [66], 'environment;': [69], 'human': [71, 124], 'half-life': [72], 'estimated': [74], 'at': [75], 'about': [76], '3': [77], 'years.': [78], 'metabolized': [82], 'body;': [85], 'it': [86, 99], 'lipophilic.': [89], 'directly': [93], 'genotoxic;': [94], 'animal': [95], 'data': [96, 206, 226], 'indicate': [97], 'that': [98], 'can': [100], 'cause': [101], 'several': [102], 'types': [103], 'tumors': [105], 'neonatal': [107], 'death': [108], 'may': [110], 'have': [111, 207], 'toxic': [112], 'effects': [113, 126, 217], 'on': [114, 122, 202], 'immune,': [116], 'liver,': [117], 'endocrine': [119], 'systems.': [120], 'Data': [121], 'health': [125], 'sparse.': [130], 'There': [131, 158], 'relatively': [133], 'consistent': [134, 164, 189], 'evidence': [135, 165, 190, 220], 'modest': [137, 168], 'positive': [138, 169], 'associations': [139], 'with': [140, 171], 'cholesterol': [141, 150], 'uric': [143], 'acid,': [144], 'although': [145], 'magnitude': [147], 'effect': [151], 'inconsistent': [153], 'across': [154], 'different': [155], 'levels.': [157], 'much': [162], 'less': [163], 'a': [167], 'correlation': [170], 'liver': [172], 'enzymes.': [173], 'Most': [174], 'findings': [175], 'come': [176], 'from': [177], 'cross-sectional': [178], 'studies,': [179], 'limiting': [180], 'conclusions.': [181], 'Two': [182], 'occupational': [183], 'cohort': [184], 'studies': [185], 'do': [186], 'provide': [188], 'chronic': [192], 'disease;': [193], 'both': [194], 'limited': [196], 'by': [197], 'sample': [198], 'size': [199], 'reliance': [201], 'mortality': [203], 'data.': [204], 'Reproductive': [205], 'increased': [208], 'recently': [209], 'inconsistent,': [212], 'any': [214, 239], 'observed': [215], 'adverse': [216], 'modest.Epidemiologic': [219], 'remains': [221], 'limited,': [222], 'date': [225], 'insufficient': [228], 'draw': [230], 'firm': [231], 'conclusions': [232], 'regarding': [233], 'role': [235], 'diseases': [242], 'concern.': [244]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2000476420', 'counts_by_year': [{'year': 2024, 'cited_by_count': 36}, {'year': 2023, 'cited_by_count': 46}, {'year': 2022, 'cited_by_count': 53}, {'year': 2021, 'cited_by_count': 49}, {'year': 2020, 'cited_by_count': 44}, {'year': 2019, 'cited_by_count': 47}, {'year': 2018, 'cited_by_count': 36}, {'year': 2017, 'cited_by_count': 38}, {'year': 2016, 'cited_by_count': 28}, {'year': 2015, 'cited_by_count': 41}, {'year': 2014, 'cited_by_count': 46}, {'year': 2013, 'cited_by_count': 40}, {'year': 2012, 'cited_by_count': 36}], 'updated_date': '2024-12-18T10:24:25.800905', 'created_date': '2016-06-24'}