Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1999703541', 'doi': 'https://doi.org/10.2165/11531450-000000000-00000', 'title': 'Oseltamivir Resistance and the H274Y Neuraminidase Mutation in Seasonal, Pandemic and Highly Pathogenic Influenza Viruses', 'display_name': 'Oseltamivir Resistance and the H274Y Neuraminidase Mutation in Seasonal, Pandemic and Highly Pathogenic Influenza Viruses', 'publication_year': 2009, 'publication_date': '2009-12-01', 'ids': {'openalex': 'https://openalex.org/W1999703541', 'doi': 'https://doi.org/10.2165/11531450-000000000-00000', 'mag': '1999703541', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/19943705'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.2165/11531450-000000000-00000', 'pdf_url': 'https://link.springer.com/content/pdf/10.2165/11531450-000000000-00000.pdf', 'source': {'id': 'https://openalex.org/S4436492', 'display_name': 'Drugs', 'issn_l': '0012-6667', 'issn': ['0012-6667', '1179-1950'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320330', 'host_organization_name': 'Adis, Springer Healthcare', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320330'], 'host_organization_lineage_names': ['Springer Nature', 'Adis, Springer Healthcare'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://link.springer.com/content/pdf/10.2165/11531450-000000000-00000.pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5025769696', 'display_name': 'Aeron C. Hurt', 'orcid': 'https://orcid.org/0000-0003-1826-4314'}, 'institutions': [{'id': 'https://openalex.org/I4210088630', 'display_name': 'Victorian Infectious Diseases Reference Laboratory', 'ror': 'https://ror.org/005ynf375', 'country_code': 'AU', 'type': 'facility', 'lineage': ['https://openalex.org/I4210088630']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Aeron C. Hurt', 'raw_affiliation_strings': ['WHO Collaborating Centre for Reference and Research on Influenza, 10 Wreckyn St, North Melbourne, Victoria, 3051, Australia'], 'affiliations': [{'raw_affiliation_string': 'WHO Collaborating Centre for Reference and Research on Influenza, 10 Wreckyn St, North Melbourne, Victoria, 3051, Australia', 'institution_ids': ['https://openalex.org/I4210088630']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5041778642', 'display_name': 'Jessica K. Holien', 'orcid': 'https://orcid.org/0000-0002-8735-2871'}, 'institutions': [{'id': 'https://openalex.org/I77826658', 'display_name': 'St Vincents Institute of Medical Research', 'ror': 'https://ror.org/02k3cxs74', 'country_code': 'AU', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I77826658']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Jessica K. Holien', 'raw_affiliation_strings': ["Structural Biology Laboratory, St Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia"], 'affiliations': [{'raw_affiliation_string': "Structural Biology Laboratory, St Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia", 'institution_ids': ['https://openalex.org/I77826658']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5002522363', 'display_name': 'Michael W. Parker', 'orcid': 'https://orcid.org/0000-0002-3101-1138'}, 'institutions': [{'id': 'https://openalex.org/I77826658', 'display_name': 'St Vincents Institute of Medical Research', 'ror': 'https://ror.org/02k3cxs74', 'country_code': 'AU', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I77826658']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Michael W. Parker', 'raw_affiliation_strings': ["Structural Biology Laboratory, St Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia"], 'affiliations': [{'raw_affiliation_string': "Structural Biology Laboratory, St Vincent's Institute of Medical Research, Fitzroy, Victoria, Australia", 'institution_ids': ['https://openalex.org/I77826658']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5073886173', 'display_name': 'Ian Barr', 'orcid': 'https://orcid.org/0000-0002-7351-418X'}, 'institutions': [{'id': 'https://openalex.org/I56590836', 'display_name': 'Monash University', 'ror': 'https://ror.org/02bfwt286', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I56590836']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Ian G. Barr', 'raw_affiliation_strings': ['School of Applied Sciences, Monash University, Churchill, Victoria, Australia'], 'affiliations': [{'raw_affiliation_string': 'School of Applied Sciences, Monash University, Churchill, Victoria, Australia', 'institution_ids': ['https://openalex.org/I56590836']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3990, 'currency': 'EUR', 'value_usd': 5290, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 5.604, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 119, 'citation_normalized_percentile': {'value': 0.946224, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '69', 'issue': '18', 'first_page': '2523', 'last_page': '2531'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10167', 'display_name': 'Influenza Virus Research Studies', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10167', 'display_name': 'Influenza Virus Research Studies', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11243', 'display_name': 'Respiratory viral infections research', 'score': 0.9802, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T13047', 'display_name': 'Pharmacological Receptor Mechanisms and Effects', 'score': 0.9781, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/zanamivir', 'display_name': 'Zanamivir', 'score': 0.94417703}, {'id': 'https://openalex.org/keywords/oseltamivir', 'display_name': 'Oseltamivir', 'score': 0.9423684}, {'id': 'https://openalex.org/keywords/neuraminidase-inhibitor', 'display_name': 'Neuraminidase inhibitor', 'score': 0.73445725}, {'id': 'https://openalex.org/keywords/rimantadine', 'display_name': 'Rimantadine', 'score': 0.6696111}, {'id': 'https://openalex.org/keywords/pandemic', 'display_name': 'Pandemic', 'score': 0.59336376}, {'id': 'https://openalex.org/keywords/amantadine', 'display_name': 'Amantadine', 'score': 0.44740868}], 'concepts': [{'id': 'https://openalex.org/C2781442963', 'wikidata': 'https://www.wikidata.org/wiki/Q146075', 'display_name': 'Zanamivir', 'level': 5, 'score': 0.94417703}, {'id': 'https://openalex.org/C2780374985', 'wikidata': 'https://www.wikidata.org/wiki/Q211509', 'display_name': 'Oseltamivir', 'level': 5, 'score': 0.9423684}, {'id': 'https://openalex.org/C134164806', 'wikidata': 'https://www.wikidata.org/wiki/Q409485', 'display_name': 'Neuraminidase', 'level': 3, 'score': 0.91396236}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.76326686}, {'id': 'https://openalex.org/C2777538117', 'wikidata': 'https://www.wikidata.org/wiki/Q425196', 'display_name': 'Neuraminidase inhibitor', 'level': 5, 'score': 0.73445725}, {'id': 'https://openalex.org/C2780391423', 'wikidata': 'https://www.wikidata.org/wiki/Q42171', 'display_name': 'Rimantadine', 'level': 4, 'score': 0.6696111}, {'id': 'https://openalex.org/C2522874641', 'wikidata': 'https://www.wikidata.org/wiki/Q808', 'display_name': 'Virus', 'level': 2, 'score': 0.6083707}, {'id': 'https://openalex.org/C89623803', 'wikidata': 'https://www.wikidata.org/wiki/Q12184', 'display_name': 'Pandemic', 'level': 5, 'score': 0.59336376}, {'id': 'https://openalex.org/C2777546802', 'wikidata': 'https://www.wikidata.org/wiki/Q834390', 'display_name': 'Influenza A virus', 'level': 3, 'score': 0.5392962}, {'id': 'https://openalex.org/C2777374534', 'wikidata': 'https://www.wikidata.org/wiki/Q409761', 'display_name': 'Amantadine', 'level': 2, 'score': 0.44740868}, {'id': 'https://openalex.org/C519248777', 'wikidata': 'https://www.wikidata.org/wiki/Q160122', 'display_name': 'Influenza A virus subtype H5N1', 'level': 3, 'score': 0.44320315}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.40490654}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.39300686}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.3618328}, {'id': 'https://openalex.org/C3008058167', 'wikidata': 'https://www.wikidata.org/wiki/Q84263196', 'display_name': 'Coronavirus disease 2019 (COVID-19)', 'level': 4, 'score': 0.11761132}, {'id': 'https://openalex.org/C524204448', 'wikidata': 'https://www.wikidata.org/wiki/Q788926', 'display_name': 'Infectious disease (medical specialty)', 'level': 3, 'score': 0.06984538}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D024882', 'descriptor_name': 'Drug Resistance, Viral', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D053118', 'descriptor_name': 'Influenza A Virus, H1N1 Subtype', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D007252', 'descriptor_name': 'Influenza Vaccines', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D009439', 'descriptor_name': 'Neuraminidase', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D053139', 'descriptor_name': 'Oseltamivir', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D011159', 'descriptor_name': 'Population Surveillance', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D012299', 'descriptor_name': 'Rimantadine', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D053243', 'descriptor_name': 'Zanamivir', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D003428', 'descriptor_name': 'Cross Infection', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D003428', 'descriptor_name': 'Cross Infection', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003428', 'descriptor_name': 'Cross Infection', 'qualifier_ui': 'Q000453', 'qualifier_name': 'epidemiology', 'is_major_topic': False}, {'descriptor_ui': 'D024882', 'descriptor_name': 'Drug Resistance, Viral', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014943', 'descriptor_name': 'Global Health', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053118', 'descriptor_name': 'Influenza A Virus, H1N1 Subtype', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053124', 'descriptor_name': 'Influenza A Virus, H5N1 Subtype', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053124', 'descriptor_name': 'Influenza A Virus, H5N1 Subtype', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D009980', 'descriptor_name': 'Influenza A virus', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D009980', 'descriptor_name': 'Influenza A virus', 'qualifier_ui': 'Q000472', 'qualifier_name': 'pathogenicity', 'is_major_topic': False}, {'descriptor_ui': 'D009980', 'descriptor_name': 'Influenza A virus', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D009980', 'descriptor_name': 'Influenza A virus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009981', 'descriptor_name': 'Influenza B virus', 'qualifier_ui': 'Q000472', 'qualifier_name': 'pathogenicity', 'is_major_topic': False}, {'descriptor_ui': 'D009981', 'descriptor_name': 'Influenza B virus', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D009981', 'descriptor_name': 'Influenza B virus', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D009981', 'descriptor_name': 'Influenza B virus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007252', 'descriptor_name': 'Influenza Vaccines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007251', 'descriptor_name': 'Influenza, Human', 'qualifier_ui': 'Q000517', 'qualifier_name': 'prevention & control', 'is_major_topic': False}, {'descriptor_ui': 'D007251', 'descriptor_name': 'Influenza, Human', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009154', 'descriptor_name': 'Mutation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009439', 'descriptor_name': 'Neuraminidase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053139', 'descriptor_name': 'Oseltamivir', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012299', 'descriptor_name': 'Rimantadine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053243', 'descriptor_name': 'Zanamivir', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.2165/11531450-000000000-00000', 'pdf_url': 'https://link.springer.com/content/pdf/10.2165/11531450-000000000-00000.pdf', 'source': {'id': 'https://openalex.org/S4436492', 'display_name': 'Drugs', 'issn_l': '0012-6667', 'issn': ['0012-6667', '1179-1950'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320330', 'host_organization_name': 'Adis, Springer Healthcare', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320330'], 'host_organization_lineage_names': ['Springer Nature', 'Adis, Springer Healthcare'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/19943705', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.2165/11531450-000000000-00000', 'pdf_url': 'https://link.springer.com/content/pdf/10.2165/11531450-000000000-00000.pdf', 'source': {'id': 'https://openalex.org/S4436492', 'display_name': 'Drugs', 'issn_l': '0012-6667', 'issn': ['0012-6667', '1179-1950'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320330', 'host_organization_name': 'Adis, Springer Healthcare', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320330'], 'host_organization_lineage_names': ['Springer Nature', 'Adis, Springer Healthcare'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.87}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 29, 'referenced_works': ['https://openalex.org/W1487246189', 'https://openalex.org/W1529484581', 'https://openalex.org/W1893105611', 'https://openalex.org/W1967579117', 'https://openalex.org/W1978487827', 'https://openalex.org/W1979485633', 'https://openalex.org/W198643845', 'https://openalex.org/W2002034570', 'https://openalex.org/W2014210710', 'https://openalex.org/W2015270682', 'https://openalex.org/W2020852349', 'https://openalex.org/W2046745698', 'https://openalex.org/W2066635136', 'https://openalex.org/W2104873628', 'https://openalex.org/W2119394949', 'https://openalex.org/W2126078732', 'https://openalex.org/W2129482297', 'https://openalex.org/W2130441728', 'https://openalex.org/W2135934555', 'https://openalex.org/W2144125773', 'https://openalex.org/W2148249666', 'https://openalex.org/W2148314825', 'https://openalex.org/W2149087734', 'https://openalex.org/W2151176095', 'https://openalex.org/W2157177671', 'https://openalex.org/W2312463092', 'https://openalex.org/W2314497776', 'https://openalex.org/W41880533', 'https://openalex.org/W4231030417'], 'related_works': ['https://openalex.org/W4367480319', 'https://openalex.org/W3107377978', 'https://openalex.org/W2522024491', 'https://openalex.org/W2343499463', 'https://openalex.org/W2119003349', 'https://openalex.org/W2043580251', 'https://openalex.org/W2039561401', 'https://openalex.org/W1999703541', 'https://openalex.org/W168938078', 'https://openalex.org/W1569528234'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1999703541', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 5}, {'year': 2022, 'cited_by_count': 9}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 7}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 9}, {'year': 2017, 'cited_by_count': 12}, {'year': 2016, 'cited_by_count': 8}, {'year': 2015, 'cited_by_count': 6}, {'year': 2014, 'cited_by_count': 10}, {'year': 2013, 'cited_by_count': 14}, {'year': 2012, 'cited_by_count': 5}], 'updated_date': '2025-01-08T18:05:21.619284', 'created_date': '2016-06-24'}