Publication Information

{'id': 'https://openalex.org/W1999185333', 'doi': 'https://doi.org/10.1111/j.1440-1681.2007.04817.x', 'title': 'DIETARY SESAMIN SUPPRESSES AORTIC NADPH OXIDASE IN DOCA SALT HYPERTENSIVE RATS', 'display_name': 'DIETARY SESAMIN SUPPRESSES AORTIC NADPH OXIDASE IN DOCA SALT HYPERTENSIVE RATS', 'publication_year': 2007, 'publication_date': '2007-10-17', 'ids': {'openalex': 'https://openalex.org/W1999185333', 'doi': 'https://doi.org/10.1111/j.1440-1681.2007.04817.x', 'mag': '1999185333', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/17941888'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1111/j.1440-1681.2007.04817.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S168193669', 'display_name': 'Clinical and Experimental Pharmacology and Physiology', 'issn_l': '0305-1870', 'issn': ['0305-1870', '1440-1681'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5040757849', 'display_name': 'Daisuke Nakano', 'orcid': 'https://orcid.org/0000-0002-7435-8465'}, 'institutions': [{'id': 'https://openalex.org/I90237989', 'display_name': 'Osaka University of Pharmaceutical Sciences', 'ror': 'https://ror.org/029yaft79', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I90237989']}, {'id': 'https://openalex.org/I25041050', 'display_name': 'Augusta University', 'ror': 'https://ror.org/012mef835', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I25041050']}], 'countries': ['JP', 'US'], 'is_corresponding': False, 'raw_author_name': 'Daisuke Nakano', 'raw_affiliation_strings': ['Laboratory of Pathological and Molecular Pharmacology, Osaka University of Pharmaceutical Sciences, Takatsuki,', 'Present address: Vascular Biology Center, Medical College of Georgia, Augusta, GA, USA.'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Pathological and Molecular Pharmacology, Osaka University of Pharmaceutical Sciences, Takatsuki,', 'institution_ids': ['https://openalex.org/I90237989']}, {'raw_affiliation_string': 'Present address: Vascular Biology Center, Medical College of Georgia, Augusta, GA, USA.', 'institution_ids': ['https://openalex.org/I25041050']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5087722596', 'display_name': 'Daisuke Kurumazuka', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I90237989', 'display_name': 'Osaka University of Pharmaceutical Sciences', 'ror': 'https://ror.org/029yaft79', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I90237989']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Daisuke Kurumazuka', 'raw_affiliation_strings': ['Laboratory of Pathological and Molecular Pharmacology, Osaka University of Pharmaceutical Sciences, Takatsuki,'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Pathological and Molecular Pharmacology, Osaka University of Pharmaceutical Sciences, Takatsuki,', 'institution_ids': ['https://openalex.org/I90237989']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5085902016', 'display_name': 'Yukiko Nagai', 'orcid': 'https://orcid.org/0000-0003-2600-626X'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Yukiko Nagai', 'raw_affiliation_strings': ['Research Equipment Center and'], 'affiliations': [{'raw_affiliation_string': 'Research Equipment Center and', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5049861668', 'display_name': 'Akira Nishiyama', 'orcid': 'https://orcid.org/0000-0001-5971-820X'}, 'institutions': [{'id': 'https://openalex.org/I201933988', 'display_name': 'Kagawa University', 'ror': 'https://ror.org/04j7mzp05', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I201933988']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Akira Nishiyama', 'raw_affiliation_strings': ['Department of Pharmacology, Kagawa University Medical School, Kida-gun, Kagawa, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology, Kagawa University Medical School, Kida-gun, Kagawa, Japan', 'institution_ids': ['https://openalex.org/I201933988']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5020299156', 'display_name': 'Yoshinobu Kiso', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210130388', 'display_name': 'Suntory Foundation for Life Sciences', 'ror': 'https://ror.org/02pkrz957', 'country_code': 'JP', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210130388']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yoshinobu Kiso', 'raw_affiliation_strings': ['Institute for Health Care Science, Suntory Ltd, Mishima-gun, Osaka,'], 'affiliations': [{'raw_affiliation_string': 'Institute for Health Care Science, Suntory Ltd, Mishima-gun, Osaka,', 'institution_ids': ['https://openalex.org/I4210130388']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5102419027', 'display_name': 'Yasuo Matsumura', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I90237989', 'display_name': 'Osaka University of Pharmaceutical Sciences', 'ror': 'https://ror.org/029yaft79', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I90237989']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yasuo Matsumura', 'raw_affiliation_strings': ['Laboratory of Pathological and Molecular Pharmacology, Osaka University of Pharmaceutical Sciences, Takatsuki,'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Pathological and Molecular Pharmacology, Osaka University of Pharmaceutical Sciences, Takatsuki,', 'institution_ids': ['https://openalex.org/I90237989']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 4, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3760, 'currency': 'USD', 'value_usd': 3760, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.82, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 64, 'citation_normalized_percentile': {'value': 0.904737, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '35', 'issue': '3', 'first_page': '324', 'last_page': '326'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T13218', 'display_name': 'Sesame and Sesamin Research', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1110', 'display_name': 'Plant Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T13218', 'display_name': 'Sesame and Sesamin Research', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1110', 'display_name': 'Plant Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11142', 'display_name': 'Advanced Glycation End Products research', 'score': 0.9773, 'subfield': {'id': 'https://openalex.org/subfields/1308', 'display_name': 'Clinical Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10387', 'display_name': 'Fatty Acid Research and Health', 'score': 0.957, 'subfield': {'id': 'https://openalex.org/subfields/2916', 'display_name': 'Nutrition and Dietetics'}, 'field': {'id': 'https://openalex.org/fields/29', 'display_name': 'Nursing'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/p22phox', 'display_name': 'P22phox', 'score': 0.9660182}, {'id': 'https://openalex.org/keywords/sesamin', 'display_name': 'Sesamin', 'score': 0.94663274}, {'id': 'https://openalex.org/keywords/nox4', 'display_name': 'NOX4', 'score': 0.8955506}, {'id': 'https://openalex.org/keywords/nox1', 'display_name': 'NOX1', 'score': 0.8141309}], 'concepts': [{'id': 'https://openalex.org/C2781308076', 'wikidata': 'https://www.wikidata.org/wiki/Q21109992', 'display_name': 'P22phox', 'level': 4, 'score': 0.9660182}, {'id': 'https://openalex.org/C2776513503', 'wikidata': 'https://www.wikidata.org/wiki/Q3511416', 'display_name': 'Sesamin', 'level': 2, 'score': 0.94663274}, {'id': 'https://openalex.org/C2779765511', 'wikidata': 'https://www.wikidata.org/wiki/Q18039812', 'display_name': 'NOX4', 'level': 4, 'score': 0.8955506}, {'id': 'https://openalex.org/C2779719074', 'wikidata': 'https://www.wikidata.org/wiki/Q2038057', 'display_name': 'NADPH oxidase', 'level': 3, 'score': 0.8813884}, {'id': 'https://openalex.org/C2776061955', 'wikidata': 'https://www.wikidata.org/wiki/Q18038565', 'display_name': 'NOX1', 'level': 4, 'score': 0.8141309}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.57306606}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.5664692}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.522817}, {'id': 'https://openalex.org/C2780795997', 'wikidata': 'https://www.wikidata.org/wiki/Q413283', 'display_name': 'Superoxide', 'level': 3, 'score': 0.51723224}, {'id': 'https://openalex.org/C38485361', 'wikidata': 'https://www.wikidata.org/wiki/Q576379', 'display_name': 'Oxidase test', 'level': 3, 'score': 0.51232207}, {'id': 'https://openalex.org/C48349386', 'wikidata': 'https://www.wikidata.org/wiki/Q424361', 'display_name': 'Reactive oxygen species', 'level': 2, 'score': 0.37842232}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.3263096}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.29247195}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.25580525}, {'id': 'https://openalex.org/C31903555', 'wikidata': 'https://www.wikidata.org/wiki/Q1637030', 'display_name': 'Food science', 'level': 1, 'score': 0.18043733}], 'mesh': [{'descriptor_ui': 'D001011', 'descriptor_name': 'Aorta', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': True}, {'descriptor_ui': 'D003900', 'descriptor_name': 'Desoxycorticosterone', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': True}, {'descriptor_ui': 'D004149', 'descriptor_name': 'Dioxoles', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D006973', 'descriptor_name': 'Hypertension', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D017705', 'descriptor_name': 'Lignans', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D019255', 'descriptor_name': 'NADPH Oxidases', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001011', 'descriptor_name': 'Aorta', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003497', 'descriptor_name': 'Cyclic N-Oxides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003497', 'descriptor_name': 'Cyclic N-Oxides', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D003900', 'descriptor_name': 'Desoxycorticosterone', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019587', 'descriptor_name': 'Dietary Supplements', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004149', 'descriptor_name': 'Dioxoles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006973', 'descriptor_name': 'Hypertension', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006973', 'descriptor_name': 'Hypertension', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': False}, {'descriptor_ui': 'D017705', 'descriptor_name': 'Lignans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019255', 'descriptor_name': 'NADPH Oxidases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017207', 'descriptor_name': 'Rats, Sprague-Dawley', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013113', 'descriptor_name': 'Spin Labels', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1111/j.1440-1681.2007.04817.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S168193669', 'display_name': 'Clinical and Experimental Pharmacology and Physiology', 'issn_l': '0305-1870', 'issn': ['0305-1870', '1440-1681'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/17941888', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 18, 'referenced_works': ['https://openalex.org/W1479733192', 'https://openalex.org/W2004725689', 'https://openalex.org/W2007274732', 'https://openalex.org/W2027942116', 'https://openalex.org/W2028375045', 'https://openalex.org/W2048324674', 'https://openalex.org/W2055679906', 'https://openalex.org/W2055772285', 'https://openalex.org/W2056228772', 'https://openalex.org/W2064009707', 'https://openalex.org/W2075775046', 'https://openalex.org/W2077746464', 'https://openalex.org/W2091201900', 'https://openalex.org/W2093050573', 'https://openalex.org/W2109791081', 'https://openalex.org/W2120215319', 'https://openalex.org/W2135802281', 'https://openalex.org/W2137088942'], 'related_works': ['https://openalex.org/W3177361848', 'https://openalex.org/W2887530025', 'https://openalex.org/W2372856071', 'https://openalex.org/W2170266244', 'https://openalex.org/W2144443864', 'https://openalex.org/W2079448980', 'https://openalex.org/W2054056852', 'https://openalex.org/W2019126109', 'https://openalex.org/W1999185333', 'https://openalex.org/W1994126631'], 'abstract_inverted_index': {'1.': [0], 'Dietary': [1], 'sesamin,': [2], 'a': [3, 54], 'sesame': [4], 'lignan,': [5], 'is': [6], 'known': [7], 'to': [8, 80, 167], 'suppress': [9], 'the': [10, 28, 71, 129, 171], 'development': [11], 'of': [12, 84, 120, 176], 'experimental': [13], 'hypertension': [14, 101], 'in': [15, 27, 131, 140, 156, 170], 'rats': [16], 'partly': [17], 'through': [18], 'its': [19], 'inhibitory': [20], 'effect': [21, 38], 'on': [22, 39], 'vascular': [23, 40], 'O(2)(-)': [24, 62, 106], 'production.': [25, 107], 'Therefore,': [26], 'present': [29], 'study,': [30], 'we': [31], 'examined': [32], 'whether': [33], 'sesamin': [34, 151], 'feeding': [35, 57, 96, 127], 'had': [36], 'any': [37], 'NADPH': [41, 65, 85, 112, 132, 157], 'oxidase': [42, 66, 86, 113, 133, 158], 'using': [43, 70], 'aortas': [44], 'from': [45], 'deoxycorticosterone': [46], 'acetate': [47], '(DOCA)': [48], 'salt': [49, 109], 'hypertensive': [50], 'rats.': [51], '2.': [52], 'After': [53], '5': [55], 'week': [56], 'and': [58, 64, 91, 102, 115, 124, 143, 160, 173], 'treatment': [59, 110], 'period,': [60], 'aortic': [61, 82, 105, 117], 'production': [63], 'activity': [67, 114, 134, 159], 'were': [68], 'measured': [69], 'lucigenin': [72], 'assay.': [73], 'Reverse': [74], 'transcription-polymerase': [75], 'chain': [76], 'reaction': [77], 'was': [78], 'performed': [79], 'analyse': [81], 'expression': [83, 119], 'subunit': [87, 161], '(p22phox,': [88], 'gp91phox,': [89, 122], 'Nox1': [90, 123, 144], 'Nox4)': [92], 'mRNA.': [93], '3.': [94], 'Sesamin': [95, 126], 'markedly': [97], 'suppressed': [98, 138], 'DOCA': [99, 108, 153], 'salt-induced': [100, 154], 'significantly': [103, 137], 'decreased': [104], 'increased': [111], 'elevated': [116], 'mRNA': [118, 145, 162], 'p22phox,': [121, 141], 'Nox4.': [125], 'abolished': [128], 'increase': [130], 'and,': [135], 'furthermore,': [136], 'increases': [139, 155], 'gp91phox': [142], 'expression.': [146, 163], '4.': [147], 'In': [148], 'conclusion,': [149], 'dietary': [150], 'prevented': [152], 'These': [164], 'effects': [165, 175], 'seem': [166], 'be': [168], 'involved': [169], 'anti-oxidant': [172], 'antihypertensive': [174], 'sesamin.': [177]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1999185333', 'counts_by_year': [{'year': 2023, 'cited_by_count': 6}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 7}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 3}, {'year': 2016, 'cited_by_count': 4}, {'year': 2015, 'cited_by_count': 8}, {'year': 2014, 'cited_by_count': 5}, {'year': 2013, 'cited_by_count': 4}, {'year': 2012, 'cited_by_count': 6}], 'updated_date': '2024-12-23T02:55:15.351358', 'created_date': '2016-06-24'}