The genetics of human obesity

Name: Work Video:
Duration: 3 min 30 s
Christopher G. Bell; Andrew J. Walley; Philippe Froguel
{'id': 'https://openalex.org/W1998979801', 'doi': 'https://doi.org/10.1038/nrg1556', 'title': 'The genetics of human obesity', 'display_name': 'The genetics of human obesity', 'publication_year': 2005, 'publication_date': '2005-02-10', 'ids': {'openalex': 'https://openalex.org/W1998979801', 'doi': 'https://doi.org/10.1038/nrg1556', 'mag': '1998979801', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/15703762'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1038/nrg1556', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S8553189', 'display_name': 'Nature Reviews Genetics', 'issn_l': '1471-0056', 'issn': ['1471-0056', '1471-0064'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319908', 'host_organization_name': 'Nature Portfolio', 'host_organization_lineage': ['https://openalex.org/P4310319908', 'https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Nature Portfolio', 'Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5091589064', 'display_name': 'Christopher G. Bell', 'orcid': 'https://orcid.org/0000-0003-4601-1242'}, 'institutions': [{'id': 'https://openalex.org/I2801748203', 'display_name': 'Hammersmith Hospital', 'ror': 'https://ror.org/05jg8yp15', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I153355300', 'https://openalex.org/I2801748203']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Christopher G. Bell', 'raw_affiliation_strings': ['Section of Genomic Medicine, Faculty of Medicine, Imperial College, Hammersmith Hospital, Du Cane Road, London, W12 0NN, UK.'], 'affiliations': [{'raw_affiliation_string': 'Section of Genomic Medicine, Faculty of Medicine, Imperial College, Hammersmith Hospital, Du Cane Road, London, W12 0NN, UK.', 'institution_ids': ['https://openalex.org/I2801748203']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5026407923', 'display_name': 'Andrew J. Walley', 'orcid': 'https://orcid.org/0000-0001-7707-7549'}, 'institutions': [{'id': 'https://openalex.org/I2801748203', 'display_name': 'Hammersmith Hospital', 'ror': 'https://ror.org/05jg8yp15', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I153355300', 'https://openalex.org/I2801748203']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Andrew J. Walley', 'raw_affiliation_strings': ['Section of Genomic Medicine, Faculty of Medicine, Imperial College, Hammersmith Hospital, London, UK'], 'affiliations': [{'raw_affiliation_string': 'Section of Genomic Medicine, Faculty of Medicine, Imperial College, Hammersmith Hospital, London, UK', 'institution_ids': ['https://openalex.org/I2801748203']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5009611870', 'display_name': 'Philippe Froguel', 'orcid': 'https://orcid.org/0000-0003-2972-0784'}, 'institutions': [{'id': 'https://openalex.org/I1294671590', 'display_name': 'Centre National de la Recherche Scientifique', 'ror': 'https://ror.org/02feahw73', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I1294671590']}, {'id': 'https://openalex.org/I2801748203', 'display_name': 'Hammersmith Hospital', 'ror': 'https://ror.org/05jg8yp15', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I153355300', 'https://openalex.org/I2801748203']}], 'countries': ['FR', 'GB'], 'is_corresponding': False, 'raw_author_name': 'Philippe Froguel', 'raw_affiliation_strings': ['Centre National de la Recherche Scientifique, 8090 Institute of Biology, Pasteur Institute, Lille, France', 'Section of Genomic Medicine, Faculty of Medicine, Imperial College, Hammersmith Hospital, London, UK'], 'affiliations': [{'raw_affiliation_string': 'Centre National de la Recherche Scientifique, 8090 Institute of Biology, Pasteur Institute, Lille, France', 'institution_ids': ['https://openalex.org/I1294671590']}, {'raw_affiliation_string': 'Section of Genomic Medicine, Faculty of Medicine, Imperial College, Hammersmith Hospital, London, UK', 'institution_ids': ['https://openalex.org/I2801748203']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 6.974, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 645, 'citation_normalized_percentile': {'value': 0.994536, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '6', 'issue': '3', 'first_page': '221', 'last_page': '234'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10489', 'display_name': 'Regulation of Appetite and Obesity', 'score': 0.9953, 'subfield': {'id': 'https://openalex.org/subfields/2807', 'display_name': 'Endocrine and Autonomic Systems'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10489', 'display_name': 'Regulation of Appetite and Obesity', 'score': 0.9953, 'subfield': {'id': 'https://openalex.org/subfields/2807', 'display_name': 'Endocrine and Autonomic Systems'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12267', 'display_name': 'Diet and metabolism studies', 'score': 0.9948, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11457', 'display_name': 'Adipose Tissue and Metabolism', 'score': 0.9946, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/identification', 'display_name': 'Identification', 'score': 0.5709713}, {'id': 'https://openalex.org/keywords/human-obesity', 'display_name': 'Human obesity', 'score': 0.53426987}, {'id': 'https://openalex.org/keywords/genetic-architecture', 'display_name': 'Genetic architecture', 'score': 0.50101304}], 'concepts': [{'id': 'https://openalex.org/C511355011', 'wikidata': 'https://www.wikidata.org/wiki/Q12174', 'display_name': 'Obesity', 'level': 2, 'score': 0.7632989}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.75594187}, {'id': 'https://openalex.org/C116834253', 'wikidata': 'https://www.wikidata.org/wiki/Q2039217', 'display_name': 'Identification (biology)', 'level': 2, 'score': 0.5709713}, {'id': 'https://openalex.org/C2992149932', 'wikidata': 'https://www.wikidata.org/wiki/Q12174', 'display_name': 'Human obesity', 'level': 3, 'score': 0.53426987}, {'id': 'https://openalex.org/C9287583', 'wikidata': 'https://www.wikidata.org/wiki/Q5532883', 'display_name': 'Genetic architecture', 'level': 4, 'score': 0.50101304}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.44409314}, {'id': 'https://openalex.org/C60644358', 'wikidata': 'https://www.wikidata.org/wiki/Q128570', 'display_name': 'Bioinformatics', 'level': 1, 'score': 0.42445648}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.41128057}, {'id': 'https://openalex.org/C127716648', 'wikidata': 'https://www.wikidata.org/wiki/Q104053', 'display_name': 'Phenotype', 'level': 3, 'score': 0.2700012}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.08851826}, {'id': 'https://openalex.org/C59822182', 'wikidata': 'https://www.wikidata.org/wiki/Q441', 'display_name': 'Botany', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D015894', 'descriptor_name': 'Genome, Human', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D009765', 'descriptor_name': 'Obesity', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D002874', 'descriptor_name': 'Chromosome Mapping', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005838', 'descriptor_name': 'Genotype', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020412', 'descriptor_name': 'Multifactorial Inheritance', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009765', 'descriptor_name': 'Obesity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1038/nrg1556', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S8553189', 'display_name': 'Nature Reviews Genetics', 'issn_l': '1471-0056', 'issn': ['1471-0056', '1471-0064'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319908', 'host_organization_name': 'Nature Portfolio', 'host_organization_lineage': ['https://openalex.org/P4310319908', 'https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Nature Portfolio', 'Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://hal.archives-ouvertes.fr/hal-00174490', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306402512', 'display_name': 'HAL (Le Centre pour la Communication Scientifique Directe)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1294671590', 'host_organization_name': 'Centre National de la Recherche Scientifique', 'host_organization_lineage': ['https://openalex.org/I1294671590'], 'host_organization_lineage_names': ['Centre National de la Recherche Scientifique'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://hal.science/hal-00174490', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306402512', 'display_name': 'HAL (Le Centre pour la Communication Scientifique Directe)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1294671590', 'host_organization_name': 'Centre National de la Recherche Scientifique', 'host_organization_lineage': ['https://openalex.org/I1294671590'], 'host_organization_lineage_names': ['Centre National de la Recherche Scientifique'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15703762', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.56}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 212, 'referenced_works': ['https://openalex.org/W1417970984', 'https://openalex.org/W1490107818', 'https://openalex.org/W1498791370', 'https://openalex.org/W1503357410', 'https://openalex.org/W1506453366', 'https://openalex.org/W1512875938', 'https://openalex.org/W1516631422', 'https://openalex.org/W1519521580', 'https://openalex.org/W1522183720', 'https://openalex.org/W1522893416', 'https://openalex.org/W1525286886', 'https://openalex.org/W1525550784', 'https://openalex.org/W1527649416', 'https://openalex.org/W1527986744', 'https://openalex.org/W154014389', 'https://openalex.org/W1541471661', 'https://openalex.org/W1572823334', 'https://openalex.org/W1584840122', 'https://openalex.org/W1606342288', 'https://openalex.org/W1631449371', 'https://openalex.org/W1639930240', 'https://openalex.org/W1670573097', 'https://openalex.org/W1718065612', 'https://openalex.org/W1896220440', 'https://openalex.org/W1935811654', 'https://openalex.org/W1965574341', 'https://openalex.org/W1967135896', 'https://openalex.org/W1970934755', 'https://openalex.org/W1973327917', 'https://openalex.org/W1974256272', 'https://openalex.org/W1978641757', 'https://openalex.org/W1978977923', 'https://openalex.org/W1980614497', 'https://openalex.org/W1980867508', 'https://openalex.org/W1983885899', 'https://openalex.org/W1985908429', 'https://openalex.org/W1988071630', 'https://openalex.org/W1988819654', 'https://openalex.org/W1990139289', 'https://openalex.org/W1993244369', 'https://openalex.org/W1996302892', 'https://openalex.org/W1996713062', 'https://openalex.org/W1997130090', 'https://openalex.org/W1997759222', 'https://openalex.org/W1999286267', 'https://openalex.org/W2000934244', 'https://openalex.org/W2001620383', 'https://openalex.org/W2001801549', 'https://openalex.org/W2001913879', 'https://openalex.org/W2003542068', 'https://openalex.org/W2003822998', 'https://openalex.org/W2005943019', 'https://openalex.org/W2006787271', 'https://openalex.org/W2008314471', 'https://openalex.org/W2009045981', 'https://openalex.org/W2010142606', 'https://openalex.org/W2010755726', 'https://openalex.org/W2010898576', 'https://openalex.org/W2011607258', 'https://openalex.org/W2011683949', 'https://openalex.org/W2015076196', 'https://openalex.org/W2015425683', 'https://openalex.org/W2015849111', 'https://openalex.org/W2015918699', 'https://openalex.org/W2016222005', 'https://openalex.org/W2016258379', 'https://openalex.org/W2019056933', 'https://openalex.org/W2021427828', 'https://openalex.org/W2021946345', 'https://openalex.org/W2022986290', 'https://openalex.org/W2024291635', 'https://openalex.org/W2025846514', 'https://openalex.org/W2026663790', 'https://openalex.org/W2027427622', 'https://openalex.org/W2029121047', 'https://openalex.org/W2029430258', 'https://openalex.org/W2034021000', 'https://openalex.org/W2034810986', 'https://openalex.org/W2036398371', 'https://openalex.org/W2036952225', 'https://openalex.org/W2039784604', 'https://openalex.org/W2040373032', 'https://openalex.org/W2041416783', 'https://openalex.org/W2042621509', 'https://openalex.org/W2042694949', 'https://openalex.org/W2045790275', 'https://openalex.org/W2048667936', 'https://openalex.org/W2050040558', 'https://openalex.org/W2050558733', 'https://openalex.org/W2052743140', 'https://openalex.org/W2054880642', 'https://openalex.org/W2056360998', 'https://openalex.org/W2059557242', 'https://openalex.org/W2060018442', 'https://openalex.org/W2060784977', 'https://openalex.org/W2060942021', 'https://openalex.org/W2063014521', 'https://openalex.org/W2063426414', 'https://openalex.org/W2065531094', 'https://openalex.org/W2066667699', 'https://openalex.org/W2066669827', 'https://openalex.org/W2067245109', 'https://openalex.org/W2067530045', 'https://openalex.org/W2068134092', 'https://openalex.org/W2069041149', 'https://openalex.org/W2069144875', 'https://openalex.org/W2071390670', 'https://openalex.org/W2072134379', 'https://openalex.org/W2074697500', 'https://openalex.org/W2078026630', 'https://openalex.org/W2081017525', 'https://openalex.org/W2082029611', 'https://openalex.org/W2083324601', 'https://openalex.org/W2087316629', 'https://openalex.org/W2088847440', 'https://openalex.org/W2090466948', 'https://openalex.org/W2091151411', 'https://openalex.org/W2091316042', 'https://openalex.org/W2092966600', 'https://openalex.org/W2093319493', 'https://openalex.org/W2094813557', 'https://openalex.org/W2095045763', 'https://openalex.org/W2095867308', 'https://openalex.org/W2096525024', 'https://openalex.org/W2098667370', 'https://openalex.org/W2099180218', 'https://openalex.org/W2099616263', 'https://openalex.org/W2101852419', 'https://openalex.org/W2102463041', 'https://openalex.org/W2102525693', 'https://openalex.org/W2103460148', 'https://openalex.org/W2105429765', 'https://openalex.org/W2105470099', 'https://openalex.org/W2106550052', 'https://openalex.org/W2107551481', 'https://openalex.org/W2111669682', 'https://openalex.org/W2111888395', 'https://openalex.org/W2112897062', 'https://openalex.org/W2114044152', 'https://openalex.org/W2114499768', 'https://openalex.org/W2116466073', 'https://openalex.org/W2117208624', 'https://openalex.org/W2117767482', 'https://openalex.org/W2118192748', 'https://openalex.org/W2118308505', 'https://openalex.org/W2118339293', 'https://openalex.org/W2118602205', 'https://openalex.org/W2119016364', 'https://openalex.org/W2120005510', 'https://openalex.org/W2120228339', 'https://openalex.org/W2120462461', 'https://openalex.org/W2120720683', 'https://openalex.org/W2121192347', 'https://openalex.org/W2121296504', 'https://openalex.org/W2123229219', 'https://openalex.org/W2123508236', 'https://openalex.org/W2124110471', 'https://openalex.org/W2125052180', 'https://openalex.org/W2125510262', 'https://openalex.org/W2129446381', 'https://openalex.org/W2133843602', 'https://openalex.org/W2134662886', 'https://openalex.org/W2136437813', 'https://openalex.org/W2139226057', 'https://openalex.org/W2140923468', 'https://openalex.org/W2141662760', 'https://openalex.org/W2142004686', 'https://openalex.org/W2142365461', 'https://openalex.org/W2143497221', 'https://openalex.org/W2143902469', 'https://openalex.org/W2144379262', 'https://openalex.org/W2144392815', 'https://openalex.org/W2147888023', 'https://openalex.org/W2150804210', 'https://openalex.org/W2154730509', 'https://openalex.org/W2157226283', 'https://openalex.org/W2159645411', 'https://openalex.org/W2159829835', 'https://openalex.org/W2160233784', 'https://openalex.org/W2160552788', 'https://openalex.org/W2160589226', 'https://openalex.org/W2160859079', 'https://openalex.org/W2161126620', 'https://openalex.org/W2162721714', 'https://openalex.org/W2164478479', 'https://openalex.org/W2165953630', 'https://openalex.org/W2168184182', 'https://openalex.org/W2168293539', 'https://openalex.org/W2169066706', 'https://openalex.org/W2186853760', 'https://openalex.org/W223502698', 'https://openalex.org/W2265687025', 'https://openalex.org/W2312451657', 'https://openalex.org/W2317860856', 'https://openalex.org/W2318485599', 'https://openalex.org/W2319176243', 'https://openalex.org/W2319231450', 'https://openalex.org/W2319361543', 'https://openalex.org/W2333875985', 'https://openalex.org/W2334252978', 'https://openalex.org/W2334337188', 'https://openalex.org/W2335145280', 'https://openalex.org/W2336925169', 'https://openalex.org/W2400562533', 'https://openalex.org/W2519064875', 'https://openalex.org/W2763739464', 'https://openalex.org/W2916596946', 'https://openalex.org/W4327878057', 'https://openalex.org/W54786159', 'https://openalex.org/W75828125', 'https://openalex.org/W82809700', 'https://openalex.org/W91106440'], 'related_works': ['https://openalex.org/W4206198331', 'https://openalex.org/W4200261624', 'https://openalex.org/W321314377', 'https://openalex.org/W2994158260', 'https://openalex.org/W2407627124', 'https://openalex.org/W2368164840', 'https://openalex.org/W2149663148', 'https://openalex.org/W2105168483', 'https://openalex.org/W2033242980', 'https://openalex.org/W1553579314'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1998979801', 'counts_by_year': [{'year': 2024, 'cited_by_count': 6}, {'year': 2023, 'cited_by_count': 14}, {'year': 2022, 'cited_by_count': 11}, {'year': 2021, 'cited_by_count': 30}, {'year': 2020, 'cited_by_count': 19}, {'year': 2019, 'cited_by_count': 29}, {'year': 2018, 'cited_by_count': 24}, {'year': 2017, 'cited_by_count': 28}, {'year': 2016, 'cited_by_count': 29}, {'year': 2015, 'cited_by_count': 36}, {'year': 2014, 'cited_by_count': 39}, {'year': 2013, 'cited_by_count': 43}, {'year': 2012, 'cited_by_count': 41}], 'updated_date': '2025-01-08T23:04:17.667208', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
