Publication Information

{'id': 'https://openalex.org/W1997231952', 'doi': 'https://doi.org/10.1002/mrm.1910320206', 'title': 'Intracellular and extracellular spaces and the direct quantification of molar intracellular concentrations of phosphorus metabolites in the isolated rat heart using <sup>31</sup>P NMR spectroscopy and phosphonate markers', 'display_name': 'Intracellular and extracellular spaces and the direct quantification of molar intracellular concentrations of phosphorus metabolites in the isolated rat heart using <sup>31</sup>P NMR spectroscopy and phosphonate markers', 'publication_year': 1994, 'publication_date': '1994-08-01', 'ids': {'openalex': 'https://openalex.org/W1997231952', 'doi': 'https://doi.org/10.1002/mrm.1910320206', 'mag': '1997231952', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/7968440'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/mrm.1910320206', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S111160002', 'display_name': 'Magnetic Resonance in Medicine', 'issn_l': '0740-3194', 'issn': ['0740-3194', '1522-2594'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5004025656', 'display_name': 'Kieran Clarke', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210096059', 'display_name': 'Institute for Biological Sciences', 'ror': 'https://ror.org/00t7c0489', 'country_code': 'CA', 'type': 'facility', 'lineage': ['https://openalex.org/I4210096059', 'https://openalex.org/I4210159778']}, {'id': 'https://openalex.org/I40120149', 'display_name': 'University of Oxford', 'ror': 'https://ror.org/052gg0110', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I40120149']}], 'countries': ['CA', 'GB'], 'is_corresponding': False, 'raw_author_name': 'Kieran Clarke', 'raw_affiliation_strings': ['Biomedical NMR, Institute for Biological Sciences, National Research Council, Ottawa, Ontario, Canada', 'University of Oxford, Department of Biochemistry, South Parks Road, Oxford OX1 3QU, United Kingdom'], 'affiliations': [{'raw_affiliation_string': 'Biomedical NMR, Institute for Biological Sciences, National Research Council, Ottawa, Ontario, Canada', 'institution_ids': ['https://openalex.org/I4210096059']}, {'raw_affiliation_string': 'University of Oxford, Department of Biochemistry, South Parks Road, Oxford OX1 3QU, United Kingdom', 'institution_ids': ['https://openalex.org/I40120149']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110990156', 'display_name': 'R. E. Anderson', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1335113835', 'display_name': 'Karolinska University Hospital', 'ror': 'https://ror.org/00m8d6786', 'country_code': 'SE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1335113835']}], 'countries': ['SE'], 'is_corresponding': False, 'raw_author_name': 'Russell E. Anderson', 'raw_affiliation_strings': ['Department of Cardiothoracic Anaesthetics and Intensive Care, Karolinska Hospital, Stockholm, Sweden'], 'affiliations': [{'raw_affiliation_string': 'Department of Cardiothoracic Anaesthetics and Intensive Care, Karolinska Hospital, Stockholm, Sweden', 'institution_ids': ['https://openalex.org/I1335113835']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5009214972', 'display_name': 'Jean‐François Nédélec', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210103368', 'display_name': 'Centre hospitalier de Rouffach', 'ror': 'https://ror.org/01extmz43', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210103368']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Jean‐François Nédélec', 'raw_affiliation_strings': ['FORENAP, Magnetic Resonance Unit, Hospital Center, Rouffach, France'], 'affiliations': [{'raw_affiliation_string': 'FORENAP, Magnetic Resonance Unit, Hospital Center, Rouffach, France', 'institution_ids': ['https://openalex.org/I4210103368']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5052118573', 'display_name': 'David O. Foster', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210145699', 'display_name': 'National Research Council Institute for Biodiagnostics', 'ror': 'https://ror.org/043b26x63', 'country_code': 'CA', 'type': 'facility', 'lineage': ['https://openalex.org/I4210145699', 'https://openalex.org/I4210159778']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'David O. Foster', 'raw_affiliation_strings': ['Institute for Biodiagnostics, National Research Council, Winnipeg, Mannitoba, Canada'], 'affiliations': [{'raw_affiliation_string': 'Institute for Biodiagnostics, National Research Council, Winnipeg, Mannitoba, Canada', 'institution_ids': ['https://openalex.org/I4210145699']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5113607325', 'display_name': 'A.I. Ally', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1288894424', 'display_name': 'Health Canada', 'ror': 'https://ror.org/05p8nb362', 'country_code': 'CA', 'type': 'government', 'lineage': ['https://openalex.org/I1288894424']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'Ariff Ally', 'raw_affiliation_strings': ['Toxicology Evaluation, Health Canada, Ottawa, Ontario, Canada'], 'affiliations': [{'raw_affiliation_string': 'Toxicology Evaluation, Health Canada, Ottawa, Ontario, Canada', 'institution_ids': ['https://openalex.org/I1288894424']}]}], 'institution_assertions': [], 'countries_distinct_count': 4, 'institutions_distinct_count': 6, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3500, 'currency': 'USD', 'value_usd': 3500, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.352, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 49, 'citation_normalized_percentile': {'value': 0.849297, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 92, 'max': 93}, 'biblio': {'volume': '32', 'issue': '2', 'first_page': '181', 'last_page': '188'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10378', 'display_name': 'Advanced MRI Techniques and Applications', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10378', 'display_name': 'Advanced MRI Techniques and Applications', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10372', 'display_name': 'Cardiac Imaging and Diagnostics', 'score': 0.9971, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12381', 'display_name': 'Electron Spin Resonance Studies', 'score': 0.9957, 'subfield': {'id': 'https://openalex.org/subfields/1304', 'display_name': 'Biophysics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/creatine', 'display_name': 'Creatine', 'score': 0.68781674}, {'id': 'https://openalex.org/keywords/intracellular-ph', 'display_name': 'Intracellular pH', 'score': 0.66739136}], 'concepts': [{'id': 'https://openalex.org/C28406088', 'wikidata': 'https://www.wikidata.org/wiki/Q5571762', 'display_name': 'Extracellular', 'level': 2, 'score': 0.9289838}, {'id': 'https://openalex.org/C79879829', 'wikidata': 'https://www.wikidata.org/wiki/Q5571762', 'display_name': 'Intracellular', 'level': 2, 'score': 0.8392257}, {'id': 'https://openalex.org/C2779896295', 'wikidata': 'https://www.wikidata.org/wiki/Q223600', 'display_name': 'Creatine', 'level': 2, 'score': 0.68781674}, {'id': 'https://openalex.org/C2777477808', 'wikidata': 'https://www.wikidata.org/wiki/Q407595', 'display_name': 'Metabolite', 'level': 2, 'score': 0.6813304}, {'id': 'https://openalex.org/C134897140', 'wikidata': 'https://www.wikidata.org/wiki/Q6058355', 'display_name': 'Intracellular pH', 'level': 3, 'score': 0.66739136}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.6267903}, {'id': 'https://openalex.org/C2113261', 'wikidata': 'https://www.wikidata.org/wiki/Q2914458', 'display_name': 'Extracellular fluid', 'level': 3, 'score': 0.6040833}, {'id': 'https://openalex.org/C2778626300', 'wikidata': 'https://www.wikidata.org/wiki/Q1984607', 'display_name': 'Phosphocreatine', 'level': 3, 'score': 0.5812799}, {'id': 'https://openalex.org/C66974803', 'wikidata': 'https://www.wikidata.org/wiki/Q10359898', 'display_name': 'Nuclear magnetic resonance spectroscopy', 'level': 2, 'score': 0.549486}, {'id': 'https://openalex.org/C2777132085', 'wikidata': 'https://www.wikidata.org/wiki/Q46220103', 'display_name': 'Phosphate', 'level': 2, 'score': 0.5085372}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.3848695}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.19578457}, {'id': 'https://openalex.org/C71240020', 'wikidata': 'https://www.wikidata.org/wiki/Q186011', 'display_name': 'Stereochemistry', 'level': 1, 'score': 0.13383672}, {'id': 'https://openalex.org/C2986317502', 'wikidata': 'https://www.wikidata.org/wiki/Q570714', 'display_name': 'Energy metabolism', 'level': 2, 'score': 0.12546077}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.11990148}], 'mesh': [{'descriptor_ui': 'D009682', 'descriptor_name': 'Magnetic Resonance Spectroscopy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D009206', 'descriptor_name': 'Myocardium', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D010710', 'descriptor_name': 'Phosphates', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005110', 'descriptor_name': 'Extracellular Space', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005110', 'descriptor_name': 'Extracellular Space', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D066298', 'descriptor_name': 'In Vitro Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009206', 'descriptor_name': 'Myocardium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009943', 'descriptor_name': 'Organophosphorus Compounds', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010710', 'descriptor_name': 'Phosphates', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017207', 'descriptor_name': 'Rats, Sprague-Dawley', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/mrm.1910320206', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S111160002', 'display_name': 'Magnetic Resonance in Medicine', 'issn_l': '0740-3194', 'issn': ['0740-3194', '1522-2594'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/7968440', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Clean water and sanitation', 'id': 'https://metadata.un.org/sdg/6', 'score': 0.64}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 20, 'referenced_works': ['https://openalex.org/W1540135207', 'https://openalex.org/W1581338941', 'https://openalex.org/W1674775418', 'https://openalex.org/W1982800154', 'https://openalex.org/W1991666470', 'https://openalex.org/W2008168573', 'https://openalex.org/W2016340605', 'https://openalex.org/W2021459037', 'https://openalex.org/W2042015322', 'https://openalex.org/W2049370893', 'https://openalex.org/W2055360226', 'https://openalex.org/W2064678570', 'https://openalex.org/W2065650211', 'https://openalex.org/W2071491283', 'https://openalex.org/W2075683192', 'https://openalex.org/W2084382384', 'https://openalex.org/W2110633987', 'https://openalex.org/W2129367678', 'https://openalex.org/W2166979692', 'https://openalex.org/W2258885649'], 'related_works': ['https://openalex.org/W2404753348', 'https://openalex.org/W2151760453', 'https://openalex.org/W2146774191', 'https://openalex.org/W2069826553', 'https://openalex.org/W2052899556', 'https://openalex.org/W2052758316', 'https://openalex.org/W2040391598', 'https://openalex.org/W2028946095', 'https://openalex.org/W1970627584', 'https://openalex.org/W139982068'], 'abstract_inverted_index': {'Abstract': [0], 'To': [1], 'quantify': [2], 'metabolite': [3, 156], 'and': [4, 14, 41, 53, 65, 81, 92, 101, 115, 141], 'cation': [5], 'concentrations': [6, 157], 'using': [7], 'NMR': [8, 26, 170], 'spectroscopy,': [9], 'the': [10, 58, 79, 89, 122, 151], 'volumes': [11, 56], 'of': [12, 37, 47, 96, 153], 'intracellular': [13, 52, 90, 154], 'extracellular': [15, 48, 54, 82, 127], 'spaces': [16], 'must': [17], 'be': [18], 'known.': [19], 'We': [20], 'describe': [21], 'a': [22, 35, 45, 164], 'simple': [23], '31': [24, 168], 'P': [25, 169], 'spectroscopic': [27], 'method': [28, 148], 'that': [29], 'employs': [30], 'dimethyl': [31], 'methylphosphonate': [32], '(DMMP)': [33], 'as': [34, 44, 86], 'marker': [36, 46], 'total': [38, 80], 'water': [39, 83], 'space': [40, 49, 55], 'phenylphosphoriate': [42], '(PPA)': [43], 'to': [50, 72, 135], 'determine': [51], 'in': [57, 66, 132, 158], 'isolated,': [59], 'perfused': [60, 159], 'rat': [61, 124, 160], 'heart.': [62, 125], 'In': [63], 'vivo': [64], 'vitro': [67], 'radiolabel': [68], 'studies': [69], 'were': [70, 106], 'used': [71], 'verify': [73], 'this': [74], 'method.': [75], 'The': [76, 126, 147], 'difference': [77], 'between': [78], 'spaces,': [84], 'determined': [85], 'milliliters/heart,': [87], 'gave': [88], 'volume': [91, 128], 'allowed': [93], 'direct': [94], 'calculation': [95], 'myocardial': [97], 'creatine': [98], 'phosphate,': [99], 'ATP,': [100], 'inorganic': [102], 'phosphate': [103], 'concentrations,': [104], 'which': [105], '13.4': [107], 'm': [108, 112, 117], 'M': [109, 113, 118], ',': [110, 114, 119], '10.1': [111], '3.4': [116], 'respectively,': [120], 'for': [121], 'glucose‐perfused': [123], 'decreased': [129], 'by': [130, 143], '84%': [131], 'hearts': [133], 'subjected': [134], '28': [136], 'min': [137], 'total,': [138], 'global': [139], 'ischemia': [140], 'increased': [142], '15%': [144], 'during': [145], 'reperfusion.': [146], 'described': [149], 'allows': [150], 'determination': [152], 'energy': [155], 'heart': [161], 'directly': [162], 'from': [163], 'single,': [165], 'fully': [166], 'relaxed': [167], 'spectrum.': [171]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1997231952', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-10T08:28:56.804476', 'created_date': '2016-06-24'}