Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1996908598', 'doi': 'https://doi.org/10.1038/jid.2012.331', 'title': 'IL-4 Inhibits the Melanogenesis of Normal Human Melanocytes through the JAK2–STAT6 Signaling Pathway', 'display_name': 'IL-4 Inhibits the Melanogenesis of Normal Human Melanocytes through the JAK2–STAT6 Signaling Pathway', 'publication_year': 2012, 'publication_date': '2012-09-20', 'ids': {'openalex': 'https://openalex.org/W1996908598', 'doi': 'https://doi.org/10.1038/jid.2012.331', 'mag': '1996908598', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/22992805'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1038/jid.2012.331', 'pdf_url': 'http://www.jidonline.org/article/S0022202X15360929/pdf', 'source': {'id': 'https://openalex.org/S28607811', 'display_name': 'Journal of Investigative Dermatology', 'issn_l': '0022-202X', 'issn': ['0022-202X', '1523-1747'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'http://www.jidonline.org/article/S0022202X15360929/pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5101551189', 'display_name': 'Hyun Jung Choi', 'orcid': 'https://orcid.org/0009-0008-4976-4104'}, 'institutions': [{'id': 'https://openalex.org/I77107153', 'display_name': 'Amorepacific (South Korea)', 'ror': 'https://ror.org/031p65n62', 'country_code': 'KR', 'type': 'company', 'lineage': ['https://openalex.org/I77107153']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Hyun Choi', 'raw_affiliation_strings': ['Bioscience Institute, AmorePacific Corporation R&D Center, Yongin, Gyeounggi-do, Republic of Korea'], 'affiliations': [{'raw_affiliation_string': 'Bioscience Institute, AmorePacific Corporation R&D Center, Yongin, Gyeounggi-do, Republic of Korea', 'institution_ids': ['https://openalex.org/I77107153']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101866537', 'display_name': 'Hyunjung Choi', 'orcid': 'https://orcid.org/0000-0003-4435-2801'}, 'institutions': [{'id': 'https://openalex.org/I77107153', 'display_name': 'Amorepacific (South Korea)', 'ror': 'https://ror.org/031p65n62', 'country_code': 'KR', 'type': 'company', 'lineage': ['https://openalex.org/I77107153']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Hyunjung Choi', 'raw_affiliation_strings': ['Bioscience Institute, AmorePacific Corporation R&D Center, Yongin, Gyeounggi-do, Republic of Korea'], 'affiliations': [{'raw_affiliation_string': 'Bioscience Institute, AmorePacific Corporation R&D Center, Yongin, Gyeounggi-do, Republic of Korea', 'institution_ids': ['https://openalex.org/I77107153']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101931489', 'display_name': 'Jiyeon Han', 'orcid': 'https://orcid.org/0000-0002-7606-5009'}, 'institutions': [{'id': 'https://openalex.org/I77107153', 'display_name': 'Amorepacific (South Korea)', 'ror': 'https://ror.org/031p65n62', 'country_code': 'KR', 'type': 'company', 'lineage': ['https://openalex.org/I77107153']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Jiyeon Han', 'raw_affiliation_strings': ['Bioscience Institute, AmorePacific Corporation R&D Center, Yongin, Gyeounggi-do, Republic of Korea'], 'affiliations': [{'raw_affiliation_string': 'Bioscience Institute, AmorePacific Corporation R&D Center, Yongin, Gyeounggi-do, Republic of Korea', 'institution_ids': ['https://openalex.org/I77107153']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5102135789', 'display_name': 'Sun Hee Jin', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I57664883', 'display_name': 'Ajou University', 'ror': 'https://ror.org/03tzb2h73', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I57664883']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Sun Hee Jin', 'raw_affiliation_strings': ['College of Pharmacy, Ajou University, Suwon, Gyeounggi-do, Republic of Korea'], 'affiliations': [{'raw_affiliation_string': 'College of Pharmacy, Ajou University, Suwon, Gyeounggi-do, Republic of Korea', 'institution_ids': ['https://openalex.org/I57664883']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069801335', 'display_name': 'Ju-Yearl Park', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I77107153', 'display_name': 'Amorepacific (South Korea)', 'ror': 'https://ror.org/031p65n62', 'country_code': 'KR', 'type': 'company', 'lineage': ['https://openalex.org/I77107153']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Ju-Yearl Park', 'raw_affiliation_strings': ['Bioscience Institute, AmorePacific Corporation R&D Center, Yongin, Gyeounggi-do, Republic of Korea'], 'affiliations': [{'raw_affiliation_string': 'Bioscience Institute, AmorePacific Corporation R&D Center, Yongin, Gyeounggi-do, Republic of Korea', 'institution_ids': ['https://openalex.org/I77107153']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5010758117', 'display_name': 'Dong Wook Shin', 'orcid': 'https://orcid.org/0000-0002-1262-2566'}, 'institutions': [{'id': 'https://openalex.org/I77107153', 'display_name': 'Amorepacific (South Korea)', 'ror': 'https://ror.org/031p65n62', 'country_code': 'KR', 'type': 'company', 'lineage': ['https://openalex.org/I77107153']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Dong Wook Shin', 'raw_affiliation_strings': ['Bioscience Institute, AmorePacific Corporation R&D Center, Yongin, Gyeounggi-do, Republic of Korea'], 'affiliations': [{'raw_affiliation_string': 'Bioscience Institute, AmorePacific Corporation R&D Center, Yongin, Gyeounggi-do, Republic of Korea', 'institution_ids': ['https://openalex.org/I77107153']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5064143592', 'display_name': 'Tae Ryong Lee', 'orcid': 'https://orcid.org/0000-0002-6914-1237'}, 'institutions': [{'id': 'https://openalex.org/I77107153', 'display_name': 'Amorepacific (South Korea)', 'ror': 'https://ror.org/031p65n62', 'country_code': 'KR', 'type': 'company', 'lineage': ['https://openalex.org/I77107153']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Tae Ryong Lee', 'raw_affiliation_strings': ['Bioscience Institute, AmorePacific Corporation R&D Center, Yongin, Gyeounggi-do, Republic of Korea'], 'affiliations': [{'raw_affiliation_string': 'Bioscience Institute, AmorePacific Corporation R&D Center, Yongin, Gyeounggi-do, Republic of Korea', 'institution_ids': ['https://openalex.org/I77107153']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048517054', 'display_name': 'Kwangmi Kim', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I89015989', 'display_name': 'Dankook University', 'ror': 'https://ror.org/058pdbn81', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I89015989']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Kwangmi Kim', 'raw_affiliation_strings': ['College of Pharmacy, Dankook University, Cheonan-si, Chungnam, Republic of Korea'], 'affiliations': [{'raw_affiliation_string': 'College of Pharmacy, Dankook University, Cheonan-si, Chungnam, Republic of Korea', 'institution_ids': ['https://openalex.org/I89015989']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5030770053', 'display_name': 'Ai‐Young Lee', 'orcid': 'https://orcid.org/0000-0001-7720-7833'}, 'institutions': [{'id': 'https://openalex.org/I205490536', 'display_name': 'Dongguk University', 'ror': 'https://ror.org/057q6n778', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I205490536']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Ai-Young Lee', 'raw_affiliation_strings': ['Department of Dermatology, Dongguk University School of Medicine, Goyang-si, Gyeounggi-do, Republic of Korea'], 'affiliations': [{'raw_affiliation_string': 'Department of Dermatology, Dongguk University School of Medicine, Goyang-si, Gyeounggi-do, Republic of Korea', 'institution_ids': ['https://openalex.org/I205490536']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5018847566', 'display_name': 'Minsoo Noh', 'orcid': 'https://orcid.org/0000-0002-4020-5372'}, 'institutions': [{'id': 'https://openalex.org/I57664883', 'display_name': 'Ajou University', 'ror': 'https://ror.org/03tzb2h73', 'country_code': 'KR', 'type': 'education', 'lineage': ['https://openalex.org/I57664883']}], 'countries': ['KR'], 'is_corresponding': False, 'raw_author_name': 'Minsoo Noh', 'raw_affiliation_strings': ['College of Pharmacy, Ajou University, Suwon, Gyeounggi-do, Republic of Korea'], 'affiliations': [{'raw_affiliation_string': 'College of Pharmacy, Ajou University, Suwon, Gyeounggi-do, Republic of Korea', 'institution_ids': ['https://openalex.org/I57664883']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 4, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3400, 'currency': 'USD', 'value_usd': 3400, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.733, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 77, 'citation_normalized_percentile': {'value': 0.885942, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '133', 'issue': '2', 'first_page': '528', 'last_page': '536'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11144', 'display_name': 'melanin and skin pigmentation', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11144', 'display_name': 'melanin and skin pigmentation', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11553', 'display_name': 'Acne and Rosacea Treatments and Effects', 'score': 0.9722, 'subfield': {'id': 'https://openalex.org/subfields/2708', 'display_name': 'Dermatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11013', 'display_name': 'Skin Protection and Aging', 'score': 0.963, 'subfield': {'id': 'https://openalex.org/subfields/2708', 'display_name': 'Dermatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/microphthalmia-associated-transcription-factor', 'display_name': 'Microphthalmia-associated transcription factor', 'score': 0.78766465}, {'id': 'https://openalex.org/keywords/stat6', 'display_name': 'STAT6', 'score': 0.78312916}, {'id': 'https://openalex.org/keywords/stat1', 'display_name': 'STAT1', 'score': 0.57078695}], 'concepts': [{'id': 'https://openalex.org/C177504595', 'wikidata': 'https://www.wikidata.org/wiki/Q336500', 'display_name': 'Microphthalmia-associated transcription factor', 'level': 4, 'score': 0.78766465}, {'id': 'https://openalex.org/C145430368', 'wikidata': 'https://www.wikidata.org/wiki/Q14914613', 'display_name': 'STAT6', 'level': 4, 'score': 0.78312916}, {'id': 'https://openalex.org/C2778923194', 'wikidata': 'https://www.wikidata.org/wiki/Q14912019', 'display_name': 'STAT3', 'level': 3, 'score': 0.73643833}, {'id': 'https://openalex.org/C2777003663', 'wikidata': 'https://www.wikidata.org/wiki/Q14912030', 'display_name': 'STAT1', 'level': 3, 'score': 0.57078695}, {'id': 'https://openalex.org/C107538193', 'wikidata': 'https://www.wikidata.org/wiki/Q187526', 'display_name': 'Melanin', 'level': 2, 'score': 0.5697409}, {'id': 'https://openalex.org/C11960822', 'wikidata': 'https://www.wikidata.org/wiki/Q242736', 'display_name': 'Phosphorylation', 'level': 2, 'score': 0.5617401}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.5112705}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.50596994}, {'id': 'https://openalex.org/C2778690821', 'wikidata': 'https://www.wikidata.org/wiki/Q212354', 'display_name': 'Cytokine', 'level': 2, 'score': 0.48267177}, {'id': 'https://openalex.org/C86339819', 'wikidata': 'https://www.wikidata.org/wiki/Q407384', 'display_name': 'Transcription factor', 'level': 3, 'score': 0.44516677}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.38150892}, {'id': 'https://openalex.org/C191732599', 'wikidata': 'https://www.wikidata.org/wiki/Q14865947', 'display_name': 'Interleukin 4', 'level': 3, 'score': 0.37431172}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.3566298}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.34248477}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.3288413}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.32115388}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.18176037}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.14361727}], 'mesh': [{'descriptor_ui': 'D017496', 'descriptor_name': 'Hypopigmentation', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': True}, {'descriptor_ui': 'D015847', 'descriptor_name': 'Interleukin-4', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D053614', 'descriptor_name': 'Janus Kinase 2', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008544', 'descriptor_name': 'Melanocytes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D050800', 'descriptor_name': 'STAT6 Transcription Factor', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D027682', 'descriptor_name': 'Cation Transport Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D027682', 'descriptor_name': 'Cation Transport Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D052816', 'descriptor_name': 'Foreskin', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D052816', 'descriptor_name': 'Foreskin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015870', 'descriptor_name': 'Gene Expression', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015870', 'descriptor_name': 'Gene Expression', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D015870', 'descriptor_name': 'Gene Expression', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017496', 'descriptor_name': 'Hypopigmentation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017496', 'descriptor_name': 'Hypopigmentation', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D007371', 'descriptor_name': 'Interferon-gamma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007371', 'descriptor_name': 'Interferon-gamma', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D007371', 'descriptor_name': 'Interferon-gamma', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D020381', 'descriptor_name': 'Interleukin-17', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020381', 'descriptor_name': 'Interleukin-17', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D020381', 'descriptor_name': 'Interleukin-17', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D015847', 'descriptor_name': 'Interleukin-4', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015847', 'descriptor_name': 'Interleukin-4', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D015850', 'descriptor_name': 'Interleukin-6', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015850', 'descriptor_name': 'Interleukin-6', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D053614', 'descriptor_name': 'Janus Kinase 2', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008543', 'descriptor_name': 'Melanins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008543', 'descriptor_name': 'Melanins', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D008543', 'descriptor_name': 'Melanins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D008544', 'descriptor_name': 'Melanocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008544', 'descriptor_name': 'Melanocytes', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D008544', 'descriptor_name': 'Melanocytes', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D051739', 'descriptor_name': 'Microphthalmia-Associated Transcription Factor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051739', 'descriptor_name': 'Microphthalmia-Associated Transcription Factor', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D061251', 'descriptor_name': 'Primary Cell Culture', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D034741', 'descriptor_name': 'RNA, Small Interfering', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D034741', 'descriptor_name': 'RNA, Small Interfering', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D050794', 'descriptor_name': 'STAT1 Transcription Factor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050794', 'descriptor_name': 'STAT1 Transcription Factor', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D050796', 'descriptor_name': 'STAT3 Transcription Factor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050796', 'descriptor_name': 'STAT3 Transcription Factor', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D050800', 'descriptor_name': 'STAT6 Transcription Factor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050800', 'descriptor_name': 'STAT6 Transcription Factor', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D012880', 'descriptor_name': 'Skin Pigmentation', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D012880', 'descriptor_name': 'Skin Pigmentation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014357', 'descriptor_name': 'Trypsin', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D014357', 'descriptor_name': 'Trypsin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D058951', 'descriptor_name': 'gp100 Melanoma Antigen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D058951', 'descriptor_name': 'gp100 Melanoma Antigen', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1038/jid.2012.331', 'pdf_url': 'http://www.jidonline.org/article/S0022202X15360929/pdf', 'source': {'id': 'https://openalex.org/S28607811', 'display_name': 'Journal of Investigative Dermatology', 'issn_l': '0022-202X', 'issn': ['0022-202X', '1523-1747'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/22992805', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1038/jid.2012.331', 'pdf_url': 'http://www.jidonline.org/article/S0022202X15360929/pdf', 'source': {'id': 'https://openalex.org/S28607811', 'display_name': 'Journal of Investigative Dermatology', 'issn_l': '0022-202X', 'issn': ['0022-202X', '1523-1747'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'score': 0.69, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [{'funder': 'https://openalex.org/F4320322034', 'funder_display_name': 'Ministry of Health and Welfare', 'award_id': 'A103017'}, {'funder': 'https://openalex.org/F4320322120', 'funder_display_name': 'National Research Foundation of Korea', 'award_id': None}, {'funder': 'https://openalex.org/F4320322349', 'funder_display_name': 'Ministry of Education, Science and Technology', 'award_id': '2012012738'}], 'datasets': [], 'versions': [], 'referenced_works_count': 39, 'referenced_works': ['https://openalex.org/W1548640328', 'https://openalex.org/W1602488051', 'https://openalex.org/W1650320961', 'https://openalex.org/W1657719429', 'https://openalex.org/W1858234123', 'https://openalex.org/W1962394256', 'https://openalex.org/W1965037168', 'https://openalex.org/W1968801618', 'https://openalex.org/W1968873996', 'https://openalex.org/W1978497980', 'https://openalex.org/W1985149018', 'https://openalex.org/W1990005278', 'https://openalex.org/W1996112634', 'https://openalex.org/W1998325167', 'https://openalex.org/W2002117801', 'https://openalex.org/W2003724801', 'https://openalex.org/W2011944479', 'https://openalex.org/W2013102804', 'https://openalex.org/W2034239165', 'https://openalex.org/W2037455853', 'https://openalex.org/W2043584813', 'https://openalex.org/W2051638902', 'https://openalex.org/W2052327891', 'https://openalex.org/W2054344840', 'https://openalex.org/W2057098942', 'https://openalex.org/W2061867074', 'https://openalex.org/W2075325752', 'https://openalex.org/W2092374642', 'https://openalex.org/W2093442991', 'https://openalex.org/W2099249565', 'https://openalex.org/W2102978104', 'https://openalex.org/W2112467050', 'https://openalex.org/W2127100103', 'https://openalex.org/W2129946962', 'https://openalex.org/W2138112259', 'https://openalex.org/W2146404284', 'https://openalex.org/W2152532651', 'https://openalex.org/W2160707678', 'https://openalex.org/W2164708259'], 'related_works': ['https://openalex.org/W2755734790', 'https://openalex.org/W2563471712', 'https://openalex.org/W2528433440', 'https://openalex.org/W2162688135', 'https://openalex.org/W2117219881', 'https://openalex.org/W2032763203', 'https://openalex.org/W2009163387', 'https://openalex.org/W1967570034', 'https://openalex.org/W174995411', 'https://openalex.org/W1180754862'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1996908598', 'counts_by_year': [{'year': 2024, 'cited_by_count': 11}, {'year': 2023, 'cited_by_count': 8}, {'year': 2022, 'cited_by_count': 8}, {'year': 2021, 'cited_by_count': 11}, {'year': 2020, 'cited_by_count': 6}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 7}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 6}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 7}, {'year': 2013, 'cited_by_count': 3}], 'updated_date': '2024-12-19T16:46:50.586194', 'created_date': '2016-06-24'}