Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1996558811', 'doi': 'https://doi.org/10.1007/s10384-013-0251-y', 'title': 'Long-term results of treatment with diquafosol ophthalmic solution for aqueous-deficient dry eye', 'display_name': 'Long-term results of treatment with diquafosol ophthalmic solution for aqueous-deficient dry eye', 'publication_year': 2013, 'publication_date': '2013-06-05', 'ids': {'openalex': 'https://openalex.org/W1996558811', 'doi': 'https://doi.org/10.1007/s10384-013-0251-y', 'mag': '1996558811', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/23740285'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/s10384-013-0251-y', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S171503191', 'display_name': 'Japanese Journal of Ophthalmology', 'issn_l': '0021-5155', 'issn': ['0021-5155', '1613-2246'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5054490944', 'display_name': 'Shizuka Koh', 'orcid': 'https://orcid.org/0000-0002-5402-3051'}, 'institutions': [{'id': 'https://openalex.org/I98285908', 'display_name': 'Osaka University', 'ror': 'https://ror.org/035t8zc32', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I98285908']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Shizuka Koh', 'raw_affiliation_strings': ['Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Japan;'], 'affiliations': [{'raw_affiliation_string': 'Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Japan;', 'institution_ids': ['https://openalex.org/I98285908']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111492988', 'display_name': 'Chikako Ikeda', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I98285908', 'display_name': 'Osaka University', 'ror': 'https://ror.org/035t8zc32', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I98285908']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Chikako Ikeda', 'raw_affiliation_strings': ['Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Japan;'], 'affiliations': [{'raw_affiliation_string': 'Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Japan;', 'institution_ids': ['https://openalex.org/I98285908']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110195670', 'display_name': 'Yoshihiro Takai', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I98285908', 'display_name': 'Osaka University', 'ror': 'https://ror.org/035t8zc32', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I98285908']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yoshihiro Takai', 'raw_affiliation_strings': ['Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Japan;'], 'affiliations': [{'raw_affiliation_string': 'Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Japan;', 'institution_ids': ['https://openalex.org/I98285908']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5101796158', 'display_name': 'Hitoshi Watanabe', 'orcid': 'https://orcid.org/0000-0003-2775-0066'}, 'institutions': [{'id': 'https://openalex.org/I98285908', 'display_name': 'Osaka University', 'ror': 'https://ror.org/035t8zc32', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I98285908']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Hitoshi Watanabe', 'raw_affiliation_strings': ['Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Japan;'], 'affiliations': [{'raw_affiliation_string': 'Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Japan;', 'institution_ids': ['https://openalex.org/I98285908']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5067035065', 'display_name': 'Naoyuki Maeda', 'orcid': 'https://orcid.org/0000-0001-6509-9054'}, 'institutions': [{'id': 'https://openalex.org/I98285908', 'display_name': 'Osaka University', 'ror': 'https://ror.org/035t8zc32', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I98285908']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Naoyuki Maeda', 'raw_affiliation_strings': ['Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Japan;'], 'affiliations': [{'raw_affiliation_string': 'Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Japan;', 'institution_ids': ['https://openalex.org/I98285908']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5033571681', 'display_name': 'Kohji Nishida', 'orcid': 'https://orcid.org/0000-0001-9069-3610'}, 'institutions': [{'id': 'https://openalex.org/I98285908', 'display_name': 'Osaka University', 'ror': 'https://ror.org/035t8zc32', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I98285908']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Kohji Nishida', 'raw_affiliation_strings': ['Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Japan;'], 'affiliations': [{'raw_affiliation_string': 'Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Japan;', 'institution_ids': ['https://openalex.org/I98285908']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 9.654, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 65, 'citation_normalized_percentile': {'value': 0.943366, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '57', 'issue': '5', 'first_page': '440', 'last_page': '446'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10997', 'display_name': 'Ocular Surface and Contact Lens', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10997', 'display_name': 'Ocular Surface and Contact Lens', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10250', 'display_name': 'Glaucoma and retinal disorders', 'score': 0.998, 'subfield': {'id': 'https://openalex.org/subfields/2731', 'display_name': 'Ophthalmology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11826', 'display_name': 'Ocular Infections and Treatments', 'score': 0.9948, 'subfield': {'id': 'https://openalex.org/subfields/2731', 'display_name': 'Ophthalmology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/artificial-tears', 'display_name': 'Artificial tears', 'score': 0.5861023}, {'id': 'https://openalex.org/keywords/ophthalmic-pathology', 'display_name': 'Ophthalmic pathology', 'score': 0.5777124}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.80783963}, {'id': 'https://openalex.org/C118487528', 'wikidata': 'https://www.wikidata.org/wiki/Q161437', 'display_name': 'Ophthalmology', 'level': 1, 'score': 0.78508615}, {'id': 'https://openalex.org/C2778837293', 'wikidata': 'https://www.wikidata.org/wiki/Q3320636', 'display_name': 'Artificial tears', 'level': 2, 'score': 0.5861023}, {'id': 'https://openalex.org/C159738032', 'wikidata': 'https://www.wikidata.org/wiki/Q7098087', 'display_name': 'Ophthalmic pathology', 'level': 4, 'score': 0.5777124}, {'id': 'https://openalex.org/C88785568', 'wikidata': 'https://www.wikidata.org/wiki/Q1217322', 'display_name': 'Neuro-ophthalmology', 'level': 3, 'score': 0.55288225}, {'id': 'https://openalex.org/C2776883082', 'wikidata': 'https://www.wikidata.org/wiki/Q1162694', 'display_name': 'Dry eyes', 'level': 2, 'score': 0.4805087}, {'id': 'https://openalex.org/C197934379', 'wikidata': 'https://www.wikidata.org/wiki/Q2047938', 'display_name': 'Adverse effect', 'level': 2, 'score': 0.44590345}, {'id': 'https://openalex.org/C141071460', 'wikidata': 'https://www.wikidata.org/wiki/Q40821', 'display_name': 'Surgery', 'level': 1, 'score': 0.324688}, {'id': 'https://openalex.org/C2778527774', 'wikidata': 'https://www.wikidata.org/wiki/Q159701', 'display_name': 'Glaucoma', 'level': 2, 'score': 0.19074625}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.16893488}], 'mesh': [{'descriptor_ui': 'D015352', 'descriptor_name': 'Dry Eye Syndromes', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D011122', 'descriptor_name': 'Polyphosphates', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D058912', 'descriptor_name': 'Purinergic P2Y Receptor Agonists', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D014500', 'descriptor_name': 'Uracil Nucleotides', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003228', 'descriptor_name': 'Conjunctiva', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D003228', 'descriptor_name': 'Conjunctiva', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003315', 'descriptor_name': 'Cornea', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D003315', 'descriptor_name': 'Cornea', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015352', 'descriptor_name': 'Dry Eye Syndromes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015352', 'descriptor_name': 'Dry Eye Syndromes', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019793', 'descriptor_name': 'Fluorescein', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D019793', 'descriptor_name': 'Fluorescein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005470', 'descriptor_name': 'Fluorometry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005500', 'descriptor_name': 'Follow-Up Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009883', 'descriptor_name': 'Ophthalmic Solutions', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011122', 'descriptor_name': 'Polyphosphates', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D058912', 'descriptor_name': 'Purinergic P2Y Receptor Agonists', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013666', 'descriptor_name': 'Tears', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D013666', 'descriptor_name': 'Tears', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D013666', 'descriptor_name': 'Tears', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D041623', 'descriptor_name': 'Tomography, Optical Coherence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016896', 'descriptor_name': 'Treatment Outcome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014500', 'descriptor_name': 'Uracil Nucleotides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/s10384-013-0251-y', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S171503191', 'display_name': 'Japanese Journal of Ophthalmology', 'issn_l': '0021-5155', 'issn': ['0021-5155', '1613-2246'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/23740285', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 35, 'referenced_works': ['https://openalex.org/W145780728', 'https://openalex.org/W1651036320', 'https://openalex.org/W1965137851', 'https://openalex.org/W1967987864', 'https://openalex.org/W1972723605', 'https://openalex.org/W1978463186', 'https://openalex.org/W1994414334', 'https://openalex.org/W1995865377', 'https://openalex.org/W1996639029', 'https://openalex.org/W2006365717', 'https://openalex.org/W2015750611', 'https://openalex.org/W2017918307', 'https://openalex.org/W2018888236', 'https://openalex.org/W2019111833', 'https://openalex.org/W2023278554', 'https://openalex.org/W2033012374', 'https://openalex.org/W2033543307', 'https://openalex.org/W2037922034', 'https://openalex.org/W2043581072', 'https://openalex.org/W2045123711', 'https://openalex.org/W2048158029', 'https://openalex.org/W2048608735', 'https://openalex.org/W2054186928', 'https://openalex.org/W2080839328', 'https://openalex.org/W2081283474', 'https://openalex.org/W2087340871', 'https://openalex.org/W2117393219', 'https://openalex.org/W2131907069', 'https://openalex.org/W2157224631', 'https://openalex.org/W2184413367', 'https://openalex.org/W2184917771', 'https://openalex.org/W2313816167', 'https://openalex.org/W2596391620', 'https://openalex.org/W2735954633', 'https://openalex.org/W4253363959'], 'related_works': ['https://openalex.org/W4297850889', 'https://openalex.org/W4289534908', 'https://openalex.org/W3147454663', 'https://openalex.org/W3030537508', 'https://openalex.org/W2616910126', 'https://openalex.org/W2587436937', 'https://openalex.org/W2147709410', 'https://openalex.org/W2101371140', 'https://openalex.org/W1996558811', 'https://openalex.org/W1991849106'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1996558811', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 6}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 6}, {'year': 2016, 'cited_by_count': 10}, {'year': 2015, 'cited_by_count': 15}, {'year': 2014, 'cited_by_count': 5}], 'updated_date': '2025-01-09T14:33:40.773322', 'created_date': '2016-06-24'}