Title: Idiopathic ventricular fibrillation associated with J wave and early repolarization: a really benign electrocardiographic sign?
Abstract: Evaluation of: Sudden cardiac arrest associated with early repolarization. Haiissaguerre M, Derval N, Saccher F et al.: N. Engl. J. Med. 358, 2016–2023 (2008). In patients with idiopathic ventricular fibrillation, several kinds of electrocardiographic findings have been reported. Brugada electrocardiogram (ECG), a coved-type ST-segment elevation in the right precordial leads, is a well-known electrocardiographic sign, which is related to ventricular fibrillation leading to sudden cardiac death. By contrast, J wave and early repolarization are generally considered as benign manifestations on the ECG; however, they are reported as having the potential to cause cardiac arrhythmias at experimental studies. This study revealed that J wave and early repolarization were more frequent in patients with idiopathic ventricular fibrillation compared with control subjects (31 vs 5%; p < 0.0001). Moreover, a higher incidence of recurrent ventricular fibrillation was observed in patients with J wave and early repolarization on the ECG compared with those without such abnormalities (HR: 2.1; 95% CI: 1.2–3.5; p = 0.008). This study raises a question on the general concept that J wave and early repolarization are benign electrocardiographic patterns.
Publication Year: 2009
Publication Date: 2009-05-01
Language: en
Type: letter
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 1
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