Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1995943031', 'doi': 'https://doi.org/10.1038/mi.2010.67', 'title': 'The TNF-family cytokine TL1A drives IL-13-dependent small intestinal inflammation', 'display_name': 'The TNF-family cytokine TL1A drives IL-13-dependent small intestinal inflammation', 'publication_year': 2011, 'publication_date': '2011-03-01', 'ids': {'openalex': 'https://openalex.org/W1995943031', 'doi': 'https://doi.org/10.1038/mi.2010.67', 'mag': '1995943031', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/20980995', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3437258'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1038/mi.2010.67', 'pdf_url': 'https://www.nature.com/articles/mi201067.pdf', 'source': {'id': 'https://openalex.org/S68384121', 'display_name': 'Mucosal Immunology', 'issn_l': '1933-0219', 'issn': ['1933-0219', '1935-3456'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://www.nature.com/articles/mi201067.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5091290599', 'display_name': 'Françoise Meylan', 'orcid': 'https://orcid.org/0000-0002-9279-7875'}, 'institutions': [{'id': 'https://openalex.org/I4210087962', 'display_name': 'National Institute of Arthritis and Musculoskeletal and Skin Diseases', 'ror': 'https://ror.org/006zn3t30', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210087962']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'F Meylan', 'raw_affiliation_strings': ['Immunoregulation Section, Autoimmunity Branch, NIAMS, Bethesda, Maryland, USA', 'These authors contributed equally to this work'], 'affiliations': [{'raw_affiliation_string': 'Immunoregulation Section, Autoimmunity Branch, NIAMS, Bethesda, Maryland, USA', 'institution_ids': ['https://openalex.org/I4210087962']}, {'raw_affiliation_string': 'These authors contributed equally to this work', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048463395', 'display_name': 'You Young Song', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210087962', 'display_name': 'National Institute of Arthritis and Musculoskeletal and Skin Diseases', 'ror': 'https://ror.org/006zn3t30', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210087962']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Y-J Song', 'raw_affiliation_strings': ['Immunoregulation Section, Autoimmunity Branch, NIAMS, Bethesda, Maryland, USA', 'These authors contributed equally to this work'], 'affiliations': [{'raw_affiliation_string': 'Immunoregulation Section, Autoimmunity Branch, NIAMS, Bethesda, Maryland, USA', 'institution_ids': ['https://openalex.org/I4210087962']}, {'raw_affiliation_string': 'These authors contributed equally to this work', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5056842523', 'display_name': 'Ivan J. Fuss', 'orcid': 'https://orcid.org/0000-0002-1278-2340'}, 'institutions': [], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'I Fuss', 'raw_affiliation_strings': ['Mucosal Immunology Section, Laboratory of Host Defenses, NIAID, Bethesda, Maryland, USA'], 'affiliations': [{'raw_affiliation_string': 'Mucosal Immunology Section, Laboratory of Host Defenses, NIAID, Bethesda, Maryland, USA', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5019686996', 'display_name': 'S Villarreal', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210087962', 'display_name': 'National Institute of Arthritis and Musculoskeletal and Skin Diseases', 'ror': 'https://ror.org/006zn3t30', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210087962']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'S Villarreal', 'raw_affiliation_strings': ['Immunoregulation Section, Autoimmunity Branch, NIAMS, Bethesda, Maryland, USA'], 'affiliations': [{'raw_affiliation_string': 'Immunoregulation Section, Autoimmunity Branch, NIAMS, Bethesda, Maryland, USA', 'institution_ids': ['https://openalex.org/I4210087962']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063383003', 'display_name': 'Erin Kahle', 'orcid': 'https://orcid.org/0000-0001-6060-9852'}, 'institutions': [{'id': 'https://openalex.org/I4210087962', 'display_name': 'National Institute of Arthritis and Musculoskeletal and Skin Diseases', 'ror': 'https://ror.org/006zn3t30', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210087962']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'E Kahle', 'raw_affiliation_strings': ['Immunoregulation Section, Autoimmunity Branch, NIAMS, Bethesda, Maryland, USA'], 'affiliations': [{'raw_affiliation_string': 'Immunoregulation Section, Autoimmunity Branch, NIAMS, Bethesda, Maryland, USA', 'institution_ids': ['https://openalex.org/I4210087962']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5085076996', 'display_name': 'Ian‐James Malm', 'orcid': 'https://orcid.org/0000-0002-4472-804X'}, 'institutions': [{'id': 'https://openalex.org/I4210087962', 'display_name': 'National Institute of Arthritis and Musculoskeletal and Skin Diseases', 'ror': 'https://ror.org/006zn3t30', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210087962']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'I-J Malm', 'raw_affiliation_strings': ['Immunoregulation Section, Autoimmunity Branch, NIAMS, Bethesda, Maryland, USA'], 'affiliations': [{'raw_affiliation_string': 'Immunoregulation Section, Autoimmunity Branch, NIAMS, Bethesda, Maryland, USA', 'institution_ids': ['https://openalex.org/I4210087962']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5003130158', 'display_name': 'Krishika Acharya', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210087962', 'display_name': 'National Institute of Arthritis and Musculoskeletal and Skin Diseases', 'ror': 'https://ror.org/006zn3t30', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210087962']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'K Acharya', 'raw_affiliation_strings': ['Immunoregulation Section, Autoimmunity Branch, NIAMS, Bethesda, Maryland, USA'], 'affiliations': [{'raw_affiliation_string': 'Immunoregulation Section, Autoimmunity Branch, NIAMS, Bethesda, Maryland, USA', 'institution_ids': ['https://openalex.org/I4210087962']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5047666171', 'display_name': 'Haydeé L. Ramos', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}, {'id': 'https://openalex.org/I4210087962', 'display_name': 'National Institute of Arthritis and Musculoskeletal and Skin Diseases', 'ror': 'https://ror.org/006zn3t30', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210087962']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'H L Ramos', 'raw_affiliation_strings': ['Molecular Immunology and Inflammation Branch, NIAMS, Bethesda, Maryland, USA'], 'affiliations': [{'raw_affiliation_string': 'Molecular Immunology and Inflammation Branch, NIAMS, Bethesda, Maryland, USA', 'institution_ids': ['https://openalex.org/I1299303238', 'https://openalex.org/I4210087962']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000542177', 'display_name': 'Larry Lo', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I108865366', 'display_name': 'Human Genome Sciences (United States)', 'ror': 'https://ror.org/05k1yyh03', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I108865366']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'L Lo', 'raw_affiliation_strings': ['Human Genome Sciences, Rockville, MD, USA'], 'affiliations': [{'raw_affiliation_string': 'Human Genome Sciences, Rockville, MD, USA', 'institution_ids': ['https://openalex.org/I108865366']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5006885476', 'display_name': 'Margaret Mentink‐Kane', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210134534', 'display_name': 'National Institute of Allergy and Infectious Diseases', 'ror': 'https://ror.org/043z4tv69', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210134534']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'M M Mentink-Kane', 'raw_affiliation_strings': ['Immunopathogenesis Section, Laboratory of Parasitic Diseases, NIAID, NIH Bethesda, Bethesda, Maryland, USA'], 'affiliations': [{'raw_affiliation_string': 'Immunopathogenesis Section, Laboratory of Parasitic Diseases, NIAID, NIH Bethesda, Bethesda, Maryland, USA', 'institution_ids': ['https://openalex.org/I4210134534']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5085255411', 'display_name': 'Thomas A. Wynn', 'orcid': 'https://orcid.org/0000-0002-7244-8731'}, 'institutions': [{'id': 'https://openalex.org/I4210134534', 'display_name': 'National Institute of Allergy and Infectious Diseases', 'ror': 'https://ror.org/043z4tv69', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210134534']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'T A Wynn', 'raw_affiliation_strings': ['Immunopathogenesis Section, Laboratory of Parasitic Diseases, NIAID, NIH Bethesda, Bethesda, Maryland, USA'], 'affiliations': [{'raw_affiliation_string': 'Immunopathogenesis Section, Laboratory of Parasitic Diseases, NIAID, NIH Bethesda, Bethesda, Maryland, USA', 'institution_ids': ['https://openalex.org/I4210134534']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5011729944', 'display_name': 'T-S Migone', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I108865366', 'display_name': 'Human Genome Sciences (United States)', 'ror': 'https://ror.org/05k1yyh03', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I108865366']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'T-S Migone', 'raw_affiliation_strings': ['Human Genome Sciences, Rockville, MD, USA'], 'affiliations': [{'raw_affiliation_string': 'Human Genome Sciences, Rockville, MD, USA', 'institution_ids': ['https://openalex.org/I108865366']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5053370481', 'display_name': 'Warren Strober', 'orcid': 'https://orcid.org/0000-0002-6259-2895'}, 'institutions': [], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'W Strober', 'raw_affiliation_strings': ['Mucosal Immunology Section, Laboratory of Host Defenses, NIAID, Bethesda, Maryland, USA'], 'affiliations': [{'raw_affiliation_string': 'Mucosal Immunology Section, Laboratory of Host Defenses, NIAID, Bethesda, Maryland, USA', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5022663310', 'display_name': 'Richard M. Siegel', 'orcid': 'https://orcid.org/0000-0001-5953-9893'}, 'institutions': [{'id': 'https://openalex.org/I4210087962', 'display_name': 'National Institute of Arthritis and Musculoskeletal and Skin Diseases', 'ror': 'https://ror.org/006zn3t30', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210087962']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'R M Siegel', 'raw_affiliation_strings': ['Immunoregulation Section, Autoimmunity Branch, NIAMS, Bethesda, Maryland, USA'], 'affiliations': [{'raw_affiliation_string': 'Immunoregulation Section, Autoimmunity Branch, NIAMS, Bethesda, Maryland, USA', 'institution_ids': ['https://openalex.org/I4210087962']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 4, 'corresponding_author_ids': ['https://openalex.org/A5022663310'], 'corresponding_institution_ids': ['https://openalex.org/I4210087962'], 'apc_list': {'value': 4990, 'currency': 'USD', 'value_usd': 4990, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 6.598, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 136, 'citation_normalized_percentile': {'value': 0.999922, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '4', 'issue': '2', 'first_page': '172', 'last_page': '185'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12528', 'display_name': 'Innate Lymphoid Cells in Immunity', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12528', 'display_name': 'Innate Lymphoid Cells in Immunity', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11020', 'display_name': 'Natural Killer Cells in Immunity', 'score': 0.9984, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10031', 'display_name': 'Regulatory T Cell Development and Function', 'score': 0.9881, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/regulatory-t-cells', 'display_name': 'Regulatory T Cells', 'score': 0.478542}], 'concepts': [{'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.72514576}, {'id': 'https://openalex.org/C17991360', 'wikidata': 'https://www.wikidata.org/wiki/Q21173843', 'display_name': 'Tumor necrosis factor alpha', 'level': 2, 'score': 0.6193728}, {'id': 'https://openalex.org/C2776914184', 'wikidata': 'https://www.wikidata.org/wiki/Q101991', 'display_name': 'Inflammation', 'level': 2, 'score': 0.6113657}, {'id': 'https://openalex.org/C2779727006', 'wikidata': 'https://www.wikidata.org/wiki/Q426188', 'display_name': 'FOXP3', 'level': 3, 'score': 0.58380455}, {'id': 'https://openalex.org/C2778260677', 'wikidata': 'https://www.wikidata.org/wiki/Q917447', 'display_name': 'Inflammatory bowel disease', 'level': 3, 'score': 0.5426683}, {'id': 'https://openalex.org/C2778690821', 'wikidata': 'https://www.wikidata.org/wiki/Q212354', 'display_name': 'Cytokine', 'level': 2, 'score': 0.53457975}, {'id': 'https://openalex.org/C47348012', 'wikidata': 'https://www.wikidata.org/wiki/Q99486570', 'display_name': 'Interleukin 17', 'level': 3, 'score': 0.5256418}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.44712102}, {'id': 'https://openalex.org/C2776090121', 'wikidata': 'https://www.wikidata.org/wiki/Q193529', 'display_name': 'T cell', 'level': 3, 'score': 0.44443738}, {'id': 'https://openalex.org/C2775862500', 'wikidata': 'https://www.wikidata.org/wiki/Q2453464', 'display_name': 'Colitis', 'level': 2, 'score': 0.4243915}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.3505612}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.17740357}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.17687976}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.099369526}], 'mesh': [{'descriptor_ui': 'D004751', 'descriptor_name': 'Enteritis', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D053380', 'descriptor_name': 'Tumor Necrosis Factor Ligand Superfamily Member 15', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018801', 'descriptor_name': 'CD2 Antigens', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D003092', 'descriptor_name': 'Colitis', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D003713', 'descriptor_name': 'Dendritic Cells', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D004306', 'descriptor_name': 'Dose-Response Relationship, Immunologic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051858', 'descriptor_name': 'Forkhead Transcription Factors', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D005786', 'descriptor_name': 'Gene Expression Regulation', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D023061', 'descriptor_name': 'Gene Order', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D057809', 'descriptor_name': 'HEK293 Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007156', 'descriptor_name': 'Immunologic Memory', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D015212', 'descriptor_name': 'Inflammatory Bowel Diseases', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D018793', 'descriptor_name': 'Interleukin-13', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D008213', 'descriptor_name': 'Lymphocyte Activation', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008810', 'descriptor_name': 'Mice, Inbred C57BL', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008822', 'descriptor_name': 'Mice, Transgenic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011401', 'descriptor_name': 'Promoter Regions, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053219', 'descriptor_name': 'Receptors, Tumor Necrosis Factor, Member 25', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013601', 'descriptor_name': 'T-Lymphocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1038/mi.2010.67', 'pdf_url': 'https://www.nature.com/articles/mi201067.pdf', 'source': {'id': 'https://openalex.org/S68384121', 'display_name': 'Mucosal Immunology', 'issn_l': '1933-0219', 'issn': ['1933-0219', '1935-3456'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3437258', 'pdf_url': 'https://europepmc.org/articles/pmc3437258?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3437258', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/20980995', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1038/mi.2010.67', 'pdf_url': 'https://www.nature.com/articles/mi201067.pdf', 'source': {'id': 'https://openalex.org/S68384121', 'display_name': 'Mucosal Immunology', 'issn_l': '1933-0219', 'issn': ['1933-0219', '1935-3456'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.6}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 62, 'referenced_works': ['https://openalex.org/W126500405', 'https://openalex.org/W1560419085', 'https://openalex.org/W1578322024', 'https://openalex.org/W1585378175', 'https://openalex.org/W1603996693', 'https://openalex.org/W1773874353', 'https://openalex.org/W1810491633', 'https://openalex.org/W1813646352', 'https://openalex.org/W1918582126', 'https://openalex.org/W1972926790', 'https://openalex.org/W1978824927', 'https://openalex.org/W1991753815', 'https://openalex.org/W1992153017', 'https://openalex.org/W1993764727', 'https://openalex.org/W1994266361', 'https://openalex.org/W1995720928', 'https://openalex.org/W2004751481', 'https://openalex.org/W2010692719', 'https://openalex.org/W2019870550', 'https://openalex.org/W2024263435', 'https://openalex.org/W2041442644', 'https://openalex.org/W2041589295', 'https://openalex.org/W2046486403', 'https://openalex.org/W2047882259', 'https://openalex.org/W2060493356', 'https://openalex.org/W2065708991', 'https://openalex.org/W2069426612', 'https://openalex.org/W2070715537', 'https://openalex.org/W2077417036', 'https://openalex.org/W2081951192', 'https://openalex.org/W2085652392', 'https://openalex.org/W2086356138', 'https://openalex.org/W2087221993', 'https://openalex.org/W2089800177', 'https://openalex.org/W2090429984', 'https://openalex.org/W2095105732', 'https://openalex.org/W2100690094', 'https://openalex.org/W2110015632', 'https://openalex.org/W2110957620', 'https://openalex.org/W2113198849', 'https://openalex.org/W2120499377', 'https://openalex.org/W2127432084', 'https://openalex.org/W2134276972', 'https://openalex.org/W2136361349', 'https://openalex.org/W2136589770', 'https://openalex.org/W2137167164', 'https://openalex.org/W2140206763', 'https://openalex.org/W2141679700', 'https://openalex.org/W2144836936', 'https://openalex.org/W2146153364', 'https://openalex.org/W2151164793', 'https://openalex.org/W2160683795', 'https://openalex.org/W2161792071', 'https://openalex.org/W2162012576', 'https://openalex.org/W2165554836', 'https://openalex.org/W2165872127', 'https://openalex.org/W2166060998', 'https://openalex.org/W2168647393', 'https://openalex.org/W2171525876', 'https://openalex.org/W2171997755', 'https://openalex.org/W4253323169', 'https://openalex.org/W4293279301'], 'related_works': ['https://openalex.org/W3025849401', 'https://openalex.org/W2766901706', 'https://openalex.org/W2750722062', 'https://openalex.org/W2613214396', 'https://openalex.org/W2557124335', 'https://openalex.org/W2550872987', 'https://openalex.org/W2515067185', 'https://openalex.org/W2413233050', 'https://openalex.org/W1509080832', 'https://openalex.org/W1479981577'], 'abstract_inverted_index': {'The': [0], 'tumor': [1], 'necrosis': [2], 'factor': [3], '(TNF)-family': [4], 'cytokine': [5], 'TL1A': [6, 27, 51, 118, 154], '(TNFSF15)': [7], 'costimulates': [8], 'T': [9, 53, 106, 177], 'cells': [10, 54, 107], 'through': [11], 'its': [12, 38], 'receptor': [13, 87], 'DR3': [14], '(TNFRSF25)': [15], 'and': [16, 155, 166, 174], 'is': [17, 41], 'required': [18], 'for': [19, 176], 'autoimmune': [20], 'pathology': [21, 66], 'driven': [22, 94], 'by': [23, 95], 'diverse': [24], 'T-cell': [25, 86], 'subsets.': [26], 'has': [28], 'been': [29], 'linked': [30], 'to': [31, 73], 'human': [32], 'inflammatory': [33, 63], 'bowel': [34, 65], 'disease': [35], '(IBD),': [36], 'but': [37], 'pathogenic': [39], 'role': [40], 'not': [42], 'known.': [43], 'We': [44], 'generated': [45], 'transgenic': [46], 'mice': [47, 59], 'that': [48, 67, 91, 117, 136, 160, 169], 'constitutively': [49], 'express': [50], 'in': [52, 97, 111, 162], 'or': [55], 'dendritic': [56], 'cells.': [57], 'These': [58, 76, 147], 'spontaneously': [60], 'develop': [61], 'IL-13-dependent': [62], 'small': [64, 163], 'strikingly': [68], 'resembles': [69], 'the': [70, 81, 98, 115, 120], 'intestinal': [71, 99, 143, 164], 'response': [72], 'nematode': [74], 'infections.': [75], 'changes': [77], 'were': [78, 109], 'dependent': [79], 'on': [80], 'presence': [82], 'of': [83, 122, 142], 'a': [84, 150], 'polyclonal': [85], '(TCR)': [88], 'repertoire,': [89], 'suggesting': [90], 'they': [92], 'are': [93, 172], 'components': [96], 'flora.': [100], 'Forkhead': [101], 'box': [102], 'P3': [103], '(FoxP3)-positive': [104], 'regulatory': [105], '(Tregs)': [108], 'present': [110], 'increased': [112], 'numbers': [113], 'despite': [114], 'fact': [116], 'suppresses': [119], 'generation': [121], 'inducible': [123], 'Tregs.': [124], 'Finally,': [125], 'blocking': [126], 'TL1A–DR3': [127, 170], 'interactions': [128, 138, 171], 'abrogates': [129], '2,4,6': [130], 'trinitrobenzenesulfonic': [131], 'acid': [132], '(TNBS)': [133], 'colitis,': [134], 'indicating': [135], 'these': [137], 'influence': [139], 'other': [140], 'causes': [141], 'inflammation': [144], 'as': [145], 'well.': [146], 'results': [148, 161], 'establish': [149, 168], 'novel': [151], 'link': [152], 'between': [153], 'interleukin': [156], '13': [157], '(IL-13)': [158], 'responses': [159], 'inflammation,': [165], 'also': [167], 'necessary': [173], 'sufficient': [175], 'cell-dependent': [178], 'IBD.': [179]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1995943031', 'counts_by_year': [{'year': 2024, 'cited_by_count': 6}, {'year': 2023, 'cited_by_count': 5}, {'year': 2022, 'cited_by_count': 5}, {'year': 2021, 'cited_by_count': 12}, {'year': 2020, 'cited_by_count': 5}, {'year': 2019, 'cited_by_count': 5}, {'year': 2018, 'cited_by_count': 9}, {'year': 2017, 'cited_by_count': 11}, {'year': 2016, 'cited_by_count': 14}, {'year': 2015, 'cited_by_count': 14}, {'year': 2014, 'cited_by_count': 12}, {'year': 2013, 'cited_by_count': 18}, {'year': 2012, 'cited_by_count': 12}], 'updated_date': '2024-09-09T00:36:05.700621', 'created_date': '2016-06-24'}