Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1995853598', 'doi': 'https://doi.org/10.1016/j.acthis.2012.01.006', 'title': 'MTT assay for cell viability: Intracellular localization of the formazan product is in lipid droplets', 'display_name': 'MTT assay for cell viability: Intracellular localization of the formazan product is in lipid droplets', 'publication_year': 2012, 'publication_date': '2012-02-15', 'ids': {'openalex': 'https://openalex.org/W1995853598', 'doi': 'https://doi.org/10.1016/j.acthis.2012.01.006', 'mag': '1995853598', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/22341561'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.acthis.2012.01.006', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210188353', 'display_name': 'Acta Histochemica', 'issn_l': '0065-1281', 'issn': ['0065-1281', '1618-0372'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5020536945', 'display_name': 'Juan C. Stockert', 'orcid': 'https://orcid.org/0000-0003-4187-9771'}, 'institutions': [{'id': 'https://openalex.org/I63634437', 'display_name': 'Universidad Autónoma de Madrid', 'ror': 'https://ror.org/01cby8j38', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I63634437']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Juan C. Stockert', 'raw_affiliation_strings': ['Department of Biology, Faculty of Sciences, Autonomous University of Madrid, Spain.'], 'affiliations': [{'raw_affiliation_string': 'Department of Biology, Faculty of Sciences, Autonomous University of Madrid, Spain.', 'institution_ids': ['https://openalex.org/I63634437']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091635878', 'display_name': 'Alfonso Blázquez‐Castro', 'orcid': 'https://orcid.org/0000-0002-3270-7065'}, 'institutions': [{'id': 'https://openalex.org/I63634437', 'display_name': 'Universidad Autónoma de Madrid', 'ror': 'https://ror.org/01cby8j38', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I63634437']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Alfonso Blázquez-Castro', 'raw_affiliation_strings': ['Department of Biology, Faculty of Sciences, Autonomous University of Madrid, Cantoblanco, 28049-Madrid, Spain'], 'affiliations': [{'raw_affiliation_string': 'Department of Biology, Faculty of Sciences, Autonomous University of Madrid, Cantoblanco, 28049-Madrid, Spain', 'institution_ids': ['https://openalex.org/I63634437']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5108591598', 'display_name': 'Magdalena Cañete', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I63634437', 'display_name': 'Universidad Autónoma de Madrid', 'ror': 'https://ror.org/01cby8j38', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I63634437']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Magdalena Cañete', 'raw_affiliation_strings': ['Department of Biology, Faculty of Sciences, Autonomous University of Madrid, Cantoblanco, 28049-Madrid, Spain'], 'affiliations': [{'raw_affiliation_string': 'Department of Biology, Faculty of Sciences, Autonomous University of Madrid, Cantoblanco, 28049-Madrid, Spain', 'institution_ids': ['https://openalex.org/I63634437']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5015694073', 'display_name': 'Richard W. Horobin', 'orcid': 'https://orcid.org/0000-0002-6612-6664'}, 'institutions': [{'id': 'https://openalex.org/I7882870', 'display_name': 'University of Glasgow', 'ror': 'https://ror.org/00vtgdb53', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I7882870']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Richard W. Horobin', 'raw_affiliation_strings': ['School of Life Sciences, College of Medical, Veterinary and Life Sciences, The University of Glasgow, Glasgow G12 8QQ, Scotland, UK'], 'affiliations': [{'raw_affiliation_string': 'School of Life Sciences, College of Medical, Veterinary and Life Sciences, The University of Glasgow, Glasgow G12 8QQ, Scotland, UK', 'institution_ids': ['https://openalex.org/I7882870']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5012671114', 'display_name': 'Ángeles Villanueva', 'orcid': 'https://orcid.org/0000-0002-5390-6936'}, 'institutions': [{'id': 'https://openalex.org/I63634437', 'display_name': 'Universidad Autónoma de Madrid', 'ror': 'https://ror.org/01cby8j38', 'country_code': 'ES', 'type': 'education', 'lineage': ['https://openalex.org/I63634437']}], 'countries': ['ES'], 'is_corresponding': False, 'raw_author_name': 'Ángeles Villanueva', 'raw_affiliation_strings': ['Department of Biology, Faculty of Sciences, Autonomous University of Madrid, Cantoblanco, 28049-Madrid, Spain'], 'affiliations': [{'raw_affiliation_string': 'Department of Biology, Faculty of Sciences, Autonomous University of Madrid, Cantoblanco, 28049-Madrid, Spain', 'institution_ids': ['https://openalex.org/I63634437']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 14.266, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 591, 'citation_normalized_percentile': {'value': 0.999974, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '114', 'issue': '8', 'first_page': '785', 'last_page': '796'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11190', 'display_name': '3D Printing in Biomedical Research', 'score': 0.9956, 'subfield': {'id': 'https://openalex.org/subfields/2204', 'display_name': 'Biomedical Engineering'}, 'field': {'id': 'https://openalex.org/fields/22', 'display_name': 'Engineering'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11190', 'display_name': '3D Printing in Biomedical Research', 'score': 0.9956, 'subfield': {'id': 'https://openalex.org/subfields/2204', 'display_name': 'Biomedical Engineering'}, 'field': {'id': 'https://openalex.org/fields/22', 'display_name': 'Engineering'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T12561', 'display_name': 'bioluminescence and chemiluminescence research', 'score': 0.9953, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10725', 'display_name': 'RNA Interference and Gene Delivery', 'score': 0.9911, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/formazan', 'display_name': 'Formazan', 'score': 0.99252665}, {'id': 'https://openalex.org/keywords/mtt-assay', 'display_name': 'MTT assay', 'score': 0.7692596}, {'id': 'https://openalex.org/keywords/viability-assay', 'display_name': 'Viability assay', 'score': 0.6427728}, {'id': 'https://openalex.org/keywords/colocalization', 'display_name': 'Colocalization', 'score': 0.53021514}, {'id': 'https://openalex.org/keywords/lipid-droplet', 'display_name': 'Lipid droplet', 'score': 0.428885}], 'concepts': [{'id': 'https://openalex.org/C2776892249', 'wikidata': 'https://www.wikidata.org/wiki/Q2324668', 'display_name': 'Formazan', 'level': 2, 'score': 0.99252665}, {'id': 'https://openalex.org/C2780783641', 'wikidata': 'https://www.wikidata.org/wiki/Q738686', 'display_name': 'MTT assay', 'level': 3, 'score': 0.7692596}, {'id': 'https://openalex.org/C53227056', 'wikidata': 'https://www.wikidata.org/wiki/Q189152', 'display_name': 'Viability assay', 'level': 3, 'score': 0.6427728}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.54409087}, {'id': 'https://openalex.org/C40209533', 'wikidata': 'https://www.wikidata.org/wiki/Q5147828', 'display_name': 'Colocalization', 'level': 2, 'score': 0.53021514}, {'id': 'https://openalex.org/C109316439', 'wikidata': 'https://www.wikidata.org/wiki/Q246181', 'display_name': 'Cytotoxicity', 'level': 3, 'score': 0.48859507}, {'id': 'https://openalex.org/C25095133', 'wikidata': 'https://www.wikidata.org/wiki/Q573950', 'display_name': 'Lipid droplet', 'level': 2, 'score': 0.428885}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.41972947}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.35192114}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.32118675}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.2948225}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.2795701}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.20380023}], 'mesh': [{'descriptor_ui': 'D022162', 'descriptor_name': 'Cytoplasmic Vesicles', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D005562', 'descriptor_name': 'Formazans', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D008055', 'descriptor_name': 'Lipids', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D013778', 'descriptor_name': 'Tetrazolium Salts', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D002470', 'descriptor_name': 'Cell Survival', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D002470', 'descriptor_name': 'Cell Survival', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D022162', 'descriptor_name': 'Cytoplasmic Vesicles', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D022162', 'descriptor_name': 'Cytoplasmic Vesicles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005456', 'descriptor_name': 'Fluorescent Dyes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005562', 'descriptor_name': 'Formazans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005562', 'descriptor_name': 'Formazans', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': False}, {'descriptor_ui': 'D006367', 'descriptor_name': 'HeLa Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008055', 'descriptor_name': 'Lipids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015394', 'descriptor_name': 'Molecular Structure', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010316', 'descriptor_name': 'Particle Size', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D021281', 'descriptor_name': 'Quantitative Structure-Activity Relationship', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012995', 'descriptor_name': 'Solubility', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013778', 'descriptor_name': 'Tetrazolium Salts', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': False}, {'descriptor_ui': 'D013778', 'descriptor_name': 'Tetrazolium Salts', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013844', 'descriptor_name': 'Thiazoles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.acthis.2012.01.006', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4210188353', 'display_name': 'Acta Histochemica', 'issn_l': '0065-1281', 'issn': ['0065-1281', '1618-0372'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/22341561', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 94, 'referenced_works': ['https://openalex.org/W1242727824', 'https://openalex.org/W1574188141', 'https://openalex.org/W1594474101', 'https://openalex.org/W1597240440', 'https://openalex.org/W1606010310', 'https://openalex.org/W1629179716', 'https://openalex.org/W1819048918', 'https://openalex.org/W1849819493', 'https://openalex.org/W1968823236', 'https://openalex.org/W1970401090', 'https://openalex.org/W1971408325', 'https://openalex.org/W1978042177', 'https://openalex.org/W1978066824', 'https://openalex.org/W1983552810', 'https://openalex.org/W1985143918', 'https://openalex.org/W1987244658', 'https://openalex.org/W1987320720', 'https://openalex.org/W1991436646', 'https://openalex.org/W1993202243', 'https://openalex.org/W1993570389', 'https://openalex.org/W1993943341', 'https://openalex.org/W2001649355', 'https://openalex.org/W2004331759', 'https://openalex.org/W2004650539', 'https://openalex.org/W2007106984', 'https://openalex.org/W2009147973', 'https://openalex.org/W2011113156', 'https://openalex.org/W2011909018', 'https://openalex.org/W2015642384', 'https://openalex.org/W2017435106', 'https://openalex.org/W2020166868', 'https://openalex.org/W2021000737', 'https://openalex.org/W2022742728', 'https://openalex.org/W2024214621', 'https://openalex.org/W2024561268', 'https://openalex.org/W2024956005', 'https://openalex.org/W2027653480', 'https://openalex.org/W2028364813', 'https://openalex.org/W2029537997', 'https://openalex.org/W2030260422', 'https://openalex.org/W2034112835', 'https://openalex.org/W2034314192', 'https://openalex.org/W2036537163', 'https://openalex.org/W2036871025', 'https://openalex.org/W2038104564', 'https://openalex.org/W2039359804', 'https://openalex.org/W2043863390', 'https://openalex.org/W2045481257', 'https://openalex.org/W2046919544', 'https://openalex.org/W2048495295', 'https://openalex.org/W2048539136', 'https://openalex.org/W2052268347', 'https://openalex.org/W2057776973', 'https://openalex.org/W2057909925', 'https://openalex.org/W2060412734', 'https://openalex.org/W2060646951', 'https://openalex.org/W2061449630', 'https://openalex.org/W2068102085', 'https://openalex.org/W2070246670', 'https://openalex.org/W2072227605', 'https://openalex.org/W2078492993', 'https://openalex.org/W2078927268', 'https://openalex.org/W2083663938', 'https://openalex.org/W2083698469', 'https://openalex.org/W2088257905', 'https://openalex.org/W2090570348', 'https://openalex.org/W2092913272', 'https://openalex.org/W2093815103', 'https://openalex.org/W2095209660', 'https://openalex.org/W2096255810', 'https://openalex.org/W2096356265', 'https://openalex.org/W2097053416', 'https://openalex.org/W2105023135', 'https://openalex.org/W2106170234', 'https://openalex.org/W2112791853', 'https://openalex.org/W2114918609', 'https://openalex.org/W2132878122', 'https://openalex.org/W2140927361', 'https://openalex.org/W2143158861', 'https://openalex.org/W2149797564', 'https://openalex.org/W2153022134', 'https://openalex.org/W2157461850', 'https://openalex.org/W2323609614', 'https://openalex.org/W2324626530', 'https://openalex.org/W2341769195', 'https://openalex.org/W2439044246', 'https://openalex.org/W2493020923', 'https://openalex.org/W2588623877', 'https://openalex.org/W2604060680', 'https://openalex.org/W2614532505', 'https://openalex.org/W2992553134', 'https://openalex.org/W411418526', 'https://openalex.org/W4243496733', 'https://openalex.org/W50583176'], 'related_works': ['https://openalex.org/W2472537479', 'https://openalex.org/W2394945112', 'https://openalex.org/W2374357932', 'https://openalex.org/W2096255810', 'https://openalex.org/W2079055691', 'https://openalex.org/W2053281570', 'https://openalex.org/W2048539136', 'https://openalex.org/W1995129984', 'https://openalex.org/W136652144', 'https://openalex.org/W118828521'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1995853598', 'counts_by_year': [{'year': 2024, 'cited_by_count': 43}, {'year': 2023, 'cited_by_count': 55}, {'year': 2022, 'cited_by_count': 55}, {'year': 2021, 'cited_by_count': 68}, {'year': 2020, 'cited_by_count': 54}, {'year': 2019, 'cited_by_count': 66}, {'year': 2018, 'cited_by_count': 65}, {'year': 2017, 'cited_by_count': 70}, {'year': 2016, 'cited_by_count': 33}, {'year': 2015, 'cited_by_count': 33}, {'year': 2014, 'cited_by_count': 25}, {'year': 2013, 'cited_by_count': 21}, {'year': 2012, 'cited_by_count': 3}], 'updated_date': '2025-01-06T04:25:12.163809', 'created_date': '2016-06-24'}