Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1995556774', 'doi': 'https://doi.org/10.2165/00002018-200629030-00005', 'title': 'Camptothecin and Podophyllotoxin Derivatives', 'display_name': 'Camptothecin and Podophyllotoxin Derivatives', 'publication_year': 2006, 'publication_date': '2006-01-01', 'ids': {'openalex': 'https://openalex.org/W1995556774', 'doi': 'https://doi.org/10.2165/00002018-200629030-00005', 'mag': '1995556774', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/16524321'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.2165/00002018-200629030-00005', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S49488433', 'display_name': 'Drug Safety', 'issn_l': '0114-5916', 'issn': ['0114-5916', '1179-1942'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320330', 'host_organization_name': 'Adis, Springer Healthcare', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320330'], 'host_organization_lineage_names': ['Springer Nature', 'Adis, Springer Healthcare'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5109129063', 'display_name': 'Jakob Hartmann', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I8087733', 'display_name': 'University of Tübingen', 'ror': 'https://ror.org/03a1kwz48', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I8087733']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'J??rg T Hartmann', 'raw_affiliation_strings': ['Department of Oncology/Hematology/Immunology/Pneumology/Rheumatology, Eberhard Karls University Tübingen, UKT - Medical Center II, Tübingen, Germany'], 'affiliations': [{'raw_affiliation_string': 'Department of Oncology/Hematology/Immunology/Pneumology/Rheumatology, Eberhard Karls University Tübingen, UKT - Medical Center II, Tübingen, Germany', 'institution_ids': ['https://openalex.org/I8087733']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5009101953', 'display_name': 'Hans‐Peter Lipp', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I8087733', 'display_name': 'University of Tübingen', 'ror': 'https://ror.org/03a1kwz48', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I8087733']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Hans-Peter Lipp', 'raw_affiliation_strings': ['Eberhard-Karls University Tübingen'], 'affiliations': [{'raw_affiliation_string': 'Eberhard-Karls University Tübingen', 'institution_ids': ['https://openalex.org/I8087733']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3390, 'currency': 'EUR', 'value_usd': 4390, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.029, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 131, 'citation_normalized_percentile': {'value': 0.999677, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '29', 'issue': '3', 'first_page': '209', 'last_page': '230'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11845', 'display_name': 'Cancer therapeutics and mechanisms', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11845', 'display_name': 'Cancer therapeutics and mechanisms', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12360', 'display_name': 'Plant-derived Lignans Synthesis and Bioactivity', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11752', 'display_name': 'Cancer Treatment and Pharmacology', 'score': 0.9906, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/camptothecin', 'display_name': 'Camptothecin', 'score': 0.77613795}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.8843437}, {'id': 'https://openalex.org/C2778143360', 'wikidata': 'https://www.wikidata.org/wiki/Q421193', 'display_name': 'Podophyllotoxin', 'level': 2, 'score': 0.82936764}, {'id': 'https://openalex.org/C2779682216', 'wikidata': 'https://www.wikidata.org/wiki/Q419964', 'display_name': 'Camptothecin', 'level': 2, 'score': 0.77613795}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.43014243}, {'id': 'https://openalex.org/C556039675', 'wikidata': 'https://www.wikidata.org/wiki/Q771035', 'display_name': 'Traditional medicine', 'level': 1, 'score': 0.38609663}, {'id': 'https://openalex.org/C71240020', 'wikidata': 'https://www.wikidata.org/wiki/Q186011', 'display_name': 'Stereochemistry', 'level': 1, 'score': 0.26937705}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.10980883}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.05045989}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000972', 'descriptor_name': 'Antineoplastic Agents, Phytogenic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D002166', 'descriptor_name': 'Camptothecin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D004791', 'descriptor_name': 'Enzyme Inhibitors', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': True}, {'descriptor_ui': 'D011034', 'descriptor_name': 'Podophyllotoxin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000972', 'descriptor_name': 'Antineoplastic Agents, Phytogenic', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D000972', 'descriptor_name': 'Antineoplastic Agents, Phytogenic', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D000972', 'descriptor_name': 'Antineoplastic Agents, Phytogenic', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D002166', 'descriptor_name': 'Camptothecin', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D002166', 'descriptor_name': 'Camptothecin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D002166', 'descriptor_name': 'Camptothecin', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D004791', 'descriptor_name': 'Enzyme Inhibitors', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D004791', 'descriptor_name': 'Enzyme Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011034', 'descriptor_name': 'Podophyllotoxin', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D011034', 'descriptor_name': 'Podophyllotoxin', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D011034', 'descriptor_name': 'Podophyllotoxin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D059004', 'descriptor_name': 'Topoisomerase I Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D059005', 'descriptor_name': 'Topoisomerase II Inhibitors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.2165/00002018-200629030-00005', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S49488433', 'display_name': 'Drug Safety', 'issn_l': '0114-5916', 'issn': ['0114-5916', '1179-1942'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320330', 'host_organization_name': 'Adis, Springer Healthcare', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310320330'], 'host_organization_lineage_names': ['Springer Nature', 'Adis, Springer Healthcare'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/16524321', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.58, 'id': 'https://metadata.un.org/sdg/2', 'display_name': 'Zero hunger'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 169, 'referenced_works': ['https://openalex.org/W106814647', 'https://openalex.org/W111795647', 'https://openalex.org/W1486430237', 'https://openalex.org/W1555002034', 'https://openalex.org/W1565521022', 'https://openalex.org/W1584024009', 'https://openalex.org/W1585209741', 'https://openalex.org/W1587615774', 'https://openalex.org/W1588408911', 'https://openalex.org/W1594148627', 'https://openalex.org/W1731800664', 'https://openalex.org/W1763824163', 'https://openalex.org/W1766927792', 'https://openalex.org/W1768357783', 'https://openalex.org/W1774923611', 'https://openalex.org/W1790602060', 'https://openalex.org/W1793717229', 'https://openalex.org/W1825053022', 'https://openalex.org/W1831172932', 'https://openalex.org/W1833467461', 'https://openalex.org/W1859729923', 'https://openalex.org/W1869323251', 'https://openalex.org/W1875574217', 'https://openalex.org/W1878454852', 'https://openalex.org/W1883759477', 'https://openalex.org/W1891206313', 'https://openalex.org/W1894280592', 'https://openalex.org/W1900083602', 'https://openalex.org/W1902268748', 'https://openalex.org/W1927327874', 'https://openalex.org/W1929570960', 'https://openalex.org/W1930485762', 'https://openalex.org/W1932625604', 'https://openalex.org/W1954914693', 'https://openalex.org/W1969787124', 'https://openalex.org/W1972803807', 'https://openalex.org/W1978537873', 'https://openalex.org/W1979749400', 'https://openalex.org/W1979921784', 'https://openalex.org/W1980521536', 'https://openalex.org/W1980716159', 'https://openalex.org/W1983212741', 'https://openalex.org/W1992222388', 'https://openalex.org/W1992413184', 'https://openalex.org/W1996537678', 'https://openalex.org/W1997761808', 'https://openalex.org/W1999533317', 'https://openalex.org/W1999616653', 'https://openalex.org/W2000669739', 'https://openalex.org/W2002987782', 'https://openalex.org/W2005914922', 'https://openalex.org/W2008291053', 'https://openalex.org/W2010498396', 'https://openalex.org/W2012353841', 'https://openalex.org/W2013905200', 'https://openalex.org/W2021622287', 'https://openalex.org/W2022929237', 'https://openalex.org/W2024971373', 'https://openalex.org/W2027030412', 'https://openalex.org/W2029935294', 'https://openalex.org/W2030539263', 'https://openalex.org/W2030786393', 'https://openalex.org/W2033561568', 'https://openalex.org/W2035829068', 'https://openalex.org/W2036094732', 'https://openalex.org/W2038765960', 'https://openalex.org/W2038988728', 'https://openalex.org/W2040208960', 'https://openalex.org/W2041066142', 'https://openalex.org/W2043252316', 'https://openalex.org/W2043474087', 'https://openalex.org/W2044358936', 'https://openalex.org/W2045767625', 'https://openalex.org/W2047014606', 'https://openalex.org/W2048079370', 'https://openalex.org/W2048459104', 'https://openalex.org/W2048462280', 'https://openalex.org/W2051557049', 'https://openalex.org/W2051907464', 'https://openalex.org/W2055342386', 'https://openalex.org/W2056249358', 'https://openalex.org/W2056269944', 'https://openalex.org/W2056388091', 'https://openalex.org/W2058845021', 'https://openalex.org/W2059809665', 'https://openalex.org/W2061681410', 'https://openalex.org/W2067578884', 'https://openalex.org/W2068224783', 'https://openalex.org/W2069547611', 'https://openalex.org/W2070540557', 'https://openalex.org/W2071983981', 'https://openalex.org/W2072240028', 'https://openalex.org/W2072665226', 'https://openalex.org/W2073816184', 'https://openalex.org/W2077353674', 'https://openalex.org/W2077621121', 'https://openalex.org/W2079003456', 'https://openalex.org/W2080566980', 'https://openalex.org/W2080625981', 'https://openalex.org/W2086280990', 'https://openalex.org/W2090004228', 'https://openalex.org/W2091941736', 'https://openalex.org/W2092820110', 'https://openalex.org/W2094593530', 'https://openalex.org/W2096088019', 'https://openalex.org/W2096096300', 'https://openalex.org/W2097257602', 'https://openalex.org/W2098648310', 'https://openalex.org/W2102661337', 'https://openalex.org/W2103768449', 'https://openalex.org/W2104743561', 'https://openalex.org/W2105415002', 'https://openalex.org/W2105529325', 'https://openalex.org/W2105823978', 'https://openalex.org/W2111484240', 'https://openalex.org/W2112055293', 'https://openalex.org/W2115830912', 'https://openalex.org/W2116604772', 'https://openalex.org/W2119027011', 'https://openalex.org/W2120321741', 'https://openalex.org/W2124319487', 'https://openalex.org/W2124467386', 'https://openalex.org/W2124707826', 'https://openalex.org/W2130492456', 'https://openalex.org/W2132063970', 'https://openalex.org/W2133106296', 'https://openalex.org/W2133295671', 'https://openalex.org/W2133930930', 'https://openalex.org/W2135121954', 'https://openalex.org/W2135859599', 'https://openalex.org/W2136313288', 'https://openalex.org/W2136730527', 'https://openalex.org/W2136955408', 'https://openalex.org/W2138020718', 'https://openalex.org/W2138315554', 'https://openalex.org/W2138344872', 'https://openalex.org/W2139550132', 'https://openalex.org/W2146553883', 'https://openalex.org/W2148550474', 'https://openalex.org/W2151566966', 'https://openalex.org/W2153050324', 'https://openalex.org/W2161433518', 'https://openalex.org/W2161861379', 'https://openalex.org/W2165351839', 'https://openalex.org/W2166811349', 'https://openalex.org/W2167501156', 'https://openalex.org/W2169857347', 'https://openalex.org/W2170830299', 'https://openalex.org/W2170845869', 'https://openalex.org/W2173418622', 'https://openalex.org/W2265594607', 'https://openalex.org/W2267139930', 'https://openalex.org/W2268254480', 'https://openalex.org/W2279873332', 'https://openalex.org/W2316156427', 'https://openalex.org/W2321350829', 'https://openalex.org/W2328209945', 'https://openalex.org/W2332727735', 'https://openalex.org/W2333225131', 'https://openalex.org/W2333611917', 'https://openalex.org/W2398428726', 'https://openalex.org/W2399252245', 'https://openalex.org/W2410480704', 'https://openalex.org/W2414201755', 'https://openalex.org/W2444044513', 'https://openalex.org/W33382804', 'https://openalex.org/W422063659', 'https://openalex.org/W4231530066', 'https://openalex.org/W4251365833'], 'related_works': ['https://openalex.org/W4389568370', 'https://openalex.org/W3108674512', 'https://openalex.org/W3032375762', 'https://openalex.org/W3031052312', 'https://openalex.org/W2748952813', 'https://openalex.org/W2080531066', 'https://openalex.org/W2057267277', 'https://openalex.org/W1995515455', 'https://openalex.org/W1506200166', 'https://openalex.org/W1489783725'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1995556774', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 5}, {'year': 2022, 'cited_by_count': 9}, {'year': 2021, 'cited_by_count': 9}, {'year': 2020, 'cited_by_count': 11}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 8}, {'year': 2016, 'cited_by_count': 8}, {'year': 2015, 'cited_by_count': 5}, {'year': 2014, 'cited_by_count': 7}, {'year': 2013, 'cited_by_count': 5}, {'year': 2012, 'cited_by_count': 9}], 'updated_date': '2024-12-17T02:37:02.015988', 'created_date': '2016-06-24'}