The Human Homologue of the Yeast DNA Repair and TFIIH Regulator MMS19 Is an AF-1-specific Coactivator of Estrogen Receptor

Name: Work Video:
Duration: 3 min 30 s
Xiaoyang Wu; Hui Li; J. Don Chen
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2620, 2642, 2796, 2806, 2824, 2915, 3010, 3178, 3219, 3223, 3304, 3337, 3360, 3392, 3578, 3605, 3649, 3752, 3768, 3943, 3968, 4074, 4099, 4168, 4318, 4334, 4356, 4363, 4490, 4604, 4677, 4705, 4718, 4736, 4821, 4937, 5008, 5036, 5082, 5088, 5096, 5114, 5209, 5221, 5271, 5384], 'control': [8, 200, 425], 'gene': [9, 201, 426, 534, 2645, 3429, 3454, 4795], 'expression': [10, 156, 202, 348, 427, 535, 1852, 1871, 2869, 2887, 2976, 3003, 3472, 3492, 3743], 'in': [11, 53, 104, 107, 122, 203, 245, 296, 299, 314, 428, 536, 909, 1056, 1060, 1164, 1346, 1460, 1509, 1551, 1555, 1633, 1672, 1759, 1778, 1860, 1876, 1902, 2000, 2164, 2201, 2227, 2239, 2288, 2307, 2325, 2333, 2523, 2538, 2553, 2647, 2664, 2669, 2734, 2756, 2769, 2778, 2810, 2828, 2854, 2921, 2963, 3004, 3032, 3070, 3110, 3230, 3267, 3295, 3317, 3365, 3434, 3473, 3485, 3493, 3613, 3689, 3710, 3866, 3983, 4060, 4092, 4165, 4173, 4274, 4324, 4347, 4377, 4384, 4451, 4479, 4525, 4574, 4619, 4655, 4739, 4756, 4781, 4812, 4826, 4914, 5007, 5179, 5234, 5346, 5389, 5409, 5453], 'a': [12, 35, 60, 76, 90, 109, 123, 149, 204, 227, 252, 268, 282, 301, 315, 341, 429, 491, 505, 515, 537, 899, 910, 967, 1165, 1461, 1504, 1561, 1566, 1643, 1747, 1760, 1779, 1951, 2032, 2352, 2457, 2534, 2546, 2554, 2576, 2648, 2740, 2855, 2964, 3036, 3102, 3159, 3172, 3192, 3200, 3296, 3308, 3318, 3329, 3451, 3486, 3609, 3656, 3665, 3674, 3773, 3935, 3980, 4093, 4171, 4237, 4242, 4313, 4526, 4601, 4616, 4652, 4661, 4798, 4930, 4948, 5127, 5170, 5193, 5202, 5206, 5235, 5325, 5516], 'wide': [13, 205, 430], 'array': [14, 206, 431], 'of': [15, 21, 70, 80, 102, 137, 141, 157, 173, 189, 207, 213, 262, 272, 294, 329, 333, 349, 365, 381, 432, 895, 905, 963, 974, 1161, 1335, 1352, 1452, 1463, 1636, 1730, 1734, 1746, 1750, 1768, 1794, 1803, 1853, 1872, 1882, 1892, 1979, 2027, 2080, 2089, 2100, 2112, 2146, 2217, 2226, 2428, 2495, 2506, 2569, 2616, 2662, 2732, 2743, 2752, 2761, 2839, 2848, 2880, 2900, 2936, 2944, 2970, 2981, 3028, 3043, 3105, 3113, 3126, 3135, 3162, 3175, 3197, 3215, 3220, 3272, 3313, 3315, 3332, 3353, 3368, 3375, 3404, 3420, 3442, 3444, 3450, 3496, 3505, 3518, 3525, 3535, 3561, 3570, 3594, 3623, 3637, 3655, 3683, 3698, 3707, 3731, 3744, 3762, 3776, 3825, 3863, 3879, 3894, 3903, 3905, 3951, 3954, 3964, 3986, 3989, 4002, 4054, 4066, 4087, 4162, 4264, 4302, 4310, 4329, 4350, 4374, 4448, 4462, 4507, 4510, 4513, 4563, 4577, 4588, 4613, 4709, 4721, 4743, 4754, 4763, 4773, 4779, 4785, 4791, 4803, 4815, 4886, 4912, 4920, 4929, 4944, 4993, 5023, 5029, 5040, 5074, 5102, 5108, 5124, 5130, 5174, 5225, 5273, 5282, 5316, 5340, 5344, 5351, 5391, 5402, 5412, 5451, 5469, 5491, 5500, 5511, 5519, 5526, 5572], 'biological': [16, 208, 433], 'processes.': [17, 209], 'The': [18, 42, 93, 210, 234, 285, 526, 892, 958, 1557, 1589, 1663, 1796, 1840, 1879, 1909, 1983, 2003, 2047, 2060, 2104, 2156, 2270, 2294, 2441, 2492, 2513, 2583, 2750, 2765, 2941, 3058, 3137, 3233, 3401, 3533, 3621, 3695, 3764, 3901, 4266, 4308, 4372, 4476, 4703, 4751, 4999, 5482], 'activity': [20, 69, 172, 212, 261, 364, 3419, 3530, 3537, 3616, 3626, 3761, 3791, 3878, 3950, 3963, 3982, 4080, 4183, 4593, 4778, 4811, 4911, 4928, 5028, 5134, 5350, 5393], 'the': [22, 71, 81, 98, 114, 138, 158, 170, 177, 214, 263, 273, 290, 306, 330, 350, 362, 369, 640, 655, 903, 906, 964, 1152, 1158, 1336, 1353, 1449, 1728, 1731, 1735, 1744, 1751, 1765, 1834, 1864, 1896, 1940, 1980, 1992, 2024, 2028, 2043, 2070, 2081, 2086, 2101, 2115, 2119, 2152, 2206, 2277, 2425, 2436, 2466, 2528, 2539, 2572, 2589, 2606, 2627, 2633, 2643, 2759, 2762, 2811, 2822, 2837, 2846, 2872, 2897, 2922, 2929, 2933, 3011, 3026, 3055, 3074, 3082, 3132, 3224, 3231, 3239, 3244, 3262, 3269, 3275, 3361, 3366, 3385, 3440, 3482, 3494, 3502, 3522, 3591, 3633, 3643, 3653, 3669, 3715, 3720, 3742, 3779, 3822, 3861, 3885, 3889, 3897, 3908, 3930, 3939, 3984, 3993, 4003, 4062, 4083, 4104, 4250, 4254, 4270, 4275, 4300, 4330, 4339, 4348, 4366, 4420, 4427, 4446, 4459, 4465, 4501, 4504, 4511, 4561, 4575, 4585, 4606, 4610, 4620, 4641, 4647, 4671, 4706, 4719, 4740, 4764, 4769, 4813, 4819, 4880, 4887, 4892, 4896, 4909, 4916, 4927, 4957, 4991, 5020, 5037, 5050, 5072, 5100, 5119, 5211, 5222, 5230, 5280, 5314, 5341, 5348, 5400, 5466, 5470, 5487, 5508, 5573], 'is': [24, 51, 216, 243, 643, 1331, 1446, 1456, 1602, 2516, 2521, 2585, 2622, 2755, 2808, 2819, 2826, 3227, 3540, 3647, 3945, 3970, 4269, 4305, 4336, 4423, 4667, 4675, 4691, 4733, 4759, 4996, 5002, 5032, 5067, 5084, 5169, 5227], 'mediated': [25, 217, 3928, 4337], 'by': [26, 218, 1333, 1829, 1887, 2076, 2108, 2131, 2189, 2200, 2292, 2299, 2801, 3089, 3143, 3203, 3350, 3431, 3456, 3538, 3627, 3632, 3788, 3917, 3929, 4068, 4081, 4180, 4590, 4761, 5052, 5077, 5229, 5328, 5394, 5506], 'an': [27, 185, 219, 377, 495, 1548, 1669, 1755, 1790, 2039, 2502, 3213, 3474, 3548, 3972, 4260, 4792, 4941, 5085, 5319, 5479, 5494, 5522], 'N-terminal': [28, 99, 220, 291, 496, 1569, 1801, 3046, 3886, 4084, 4642, 5488], 'ligand-independent': [29, 124, 221, 316, 497, 1166, 1780, 3319, 4527], 'activation': [31, 39, 223, 231, 499, 519, 962, 3246, 3449, 3569, 3688, 3738, 4059, 4790, 5076, 5505], 'function': [32, 40, 224, 232, 500, 520, 530, 1554, 1729, 1788, 3771, 3824, 3865, 4086, 4301, 5510, 5518], 'AF-1': [33, 171, 225, 363, 527, 1159, 1337, 1349, 3823, 3875, 3887, 3910, 3944, 3978, 3995, 4005, 4058, 4085, 4910, 4951, 4994, 5027, 5047, 5054, 5086, 5103, 5223, 5509], 'and': [34, 66, 85, 106, 226, 258, 277, 298, 438, 514, 528, 539, 759, 972, 980, 1051, 1350, 1458, 1572, 1597, 1607, 1613, 1639, 1895, 1962, 1971, 1996, 2052, 2058, 2067, 2085, 2171, 2187, 2283, 2301, 2392, 2412, 2416, 2449, 2499, 2525, 2591, 2612, 2629, 2675, 2790, 2831, 2957, 3013, 3061, 3066, 3081, 3087, 3091, 3145, 3185, 3205, 3243, 3344, 3379, 3399, 3408, 3461, 3467, 3509, 3754, 3815, 3888, 4064, 4070, 4121, 4125, 4177, 4253, 4257, 4353, 4370, 4523, 4686, 4700, 4715, 4725, 4748, 4768, 4918, 4922, 4990, 5014, 5025, 5057, 5064, 5104, 5121, 5181, 5199, 5201, 5321, 5456, 5464, 5474, 5549, 5555, 5569], 'C-terminal': [36, 111, 228, 303, 516, 2458, 2592, 2630, 3235, 3721, 3890, 4484, 4707, 4741, 4765, 5214, 5276, 5497], 'AF-2.': [41, 233, 5105], 'nuclear': [43, 235, 2817, 3240, 3284, 3293, 4516, 5078], 'receptor': [44, 64, 131, 236, 256, 323, 386, 388, 391, 409, 412, 415, 657, 907, 965, 1354, 3294, 4255, 4607], 'coactivator': [45, 188, 237, 380, 389, 658, 959, 1793, 3746, 3775, 4251, 4263, 4943, 4995, 5087, 5093, 5284, 5525], 'RAC3': [46, 103, 238, 295, 1052, 1444, 1500, 1545, 1769, 1805, 1984, 2937, 2945, 3031, 3045, 3236, 3273, 3281, 3407, 3519, 3734, 3755, 4252, 4534, 4614, 4635, 4658, 4678, 4699, 4714, 4724, 4747, 5024, 5041, 5094, 5405, 5492], '(also': [47, 239], 'known': [48, 240], 'as': [49, 89, 241, 281, 436, 978, 1630, 1632, 1754, 1770, 1789, 1915, 1947, 2242, 2356, 2439, 2566, 2775, 2777, 2783, 2888, 3274, 3664, 3772, 4241, 4259, 4312, 4940, 4956, 5192, 5318, 5478, 5521], 'AIB1/ACTR/pCIP/TRAM-1/SRC-3)': [50, 242], 'amplified': [52, 244, 1457, 1828, 1841], 'breast': [54, 246, 1464, 1511], 'cancer': [55, 247, 1512, 2737, 2771], 'cells,': [56, 248], 'where': [57, 249], 'it': [58, 250, 1455, 2500, 2520, 2906, 4169, 4690, 4732, 5009, 5031, 5218, 5268], 'forms': [59, 251], 'complex': [61, 253, 1506, 2295, 4648, 4662, 5172, 5285], 'with': [62, 97, 119, 128, 254, 289, 311, 320, 1157, 1507, 1764, 1776, 1833, 1973, 1991, 2038, 2065, 2097, 2114, 2141, 2223, 2232, 2276, 2313, 2341, 2389, 2394, 2424, 2435, 2465, 2571, 2594, 2758, 2821, 2841, 2851, 2882, 2896, 2908, 2919, 2961, 2983, 2994, 3022, 3030, 3068, 3079, 3115, 3121, 3183, 3261, 3283, 3292, 3341, 3377, 3384, 3397, 3406, 3478, 3590, 3596, 3600, 3652, 3733, 4248, 4390, 4434, 4458, 4472, 4503, 4515, 4521, 4533, 4571, 4638, 4663, 4684, 4698, 4712, 4723, 4746, 4818, 5011, 5019, 5059, 5091, 5118, 5397, 5404, 5486], 'estrogen': [63, 120, 190, 255, 312, 382, 390, 408, 5527], '(ER)': [65, 257], 'enhances': [67, 161, 259, 353, 960, 4883, 4908], 'AF-2': [68, 178, 260, 370, 529, 1351, 3877, 3891, 3913, 3932, 4932, 5060, 5092], 'receptor.': [72, 135, 191, 264, 327, 383, 4673, 5528], 'Here,': [73, 265, 1741, 4234], 'we': [74, 266, 1742, 2430, 2804, 2843, 3034, 3286, 3302, 3426, 3438, 3870, 4235, 4935, 5382, 5461], 'identify': [75, 267, 2420], 'putative': [77, 269], 'human': [78, 94, 115, 270, 286, 307, 407, 1748, 1804, 1952, 2004, 2671, 2736, 2780, 3826, 4238, 5000, 5467, 5483, 5538], 'homologue': [79, 271, 1749, 2574, 4240, 5468], 'yeast': [82, 274, 1752, 1761, 1910, 1993, 2432, 2467, 2529, 2573, 2856, 2923, 3264, 3386, 3780, 4094, 4166, 5471], 'DNA': [83, 275, 508, 1797, 1836, 1842, 1855, 1888, 2132, 2829, 3898, 4126, 5472], 'repair': [84, 276, 2830, 4176, 5184, 5473], 'regulator': [87, 279, 5476], 'MMS19': [88, 95, 116, 280, 287, 308, 1753, 1994, 2468, 2621, 2825, 3781, 3864, 4163, 4239, 5001, 5477, 5484], 'RAC3-interacting': [91, 283, 1756, 4243, 5322], 'protein.': [92, 284, 3370, 4244, 5481], 'interacts': [96, 118, 288, 310, 1775, 2917, 3282, 4247, 4389, 4532, 4637, 4711, 5010, 5018, 5090, 5116, 5485], 'PAS-A/B': [100, 292, 2953, 2984, 3270, 4340, 5489], 'domain': [101, 140, 293, 332, 406, 493, 510, 1160, 1563, 1591, 1601, 1665, 1733, 1767, 2427, 2438, 2899, 2935, 2943, 3134, 3242, 3271, 4006, 4268, 4304, 4320, 4376, 4395, 4422, 4461, 4506, 4644, 4708, 4742, 4898, 5022, 5039, 5224, 5278, 5490], 'vivo': [105, 297], 'vitrothrough': [108, 300], 'conserved': [110, 302, 1568, 1604, 2623, 4272, 4425, 4485, 5496], 'domain.': [112, 304, 3645, 3900, 4486, 4933, 5216, 5498], 'Interestingly,': [113, 305, 1151, 1772, 2660, 3188, 4052, 4342], 'also': [117, 309, 1155, 1774, 2532, 2603, 2640, 3326, 3363, 3395, 4381, 4432, 4531, 5089, 5562], 'manner': [125, 317, 541, 912, 1167, 3320, 3488, 5237], 'but': [126, 175, 318, 367, 3096, 3598, 3933, 4438], 'not': [127, 176, 319, 368, 2793, 2866, 2894, 2978, 3000, 3097, 3156, 3228, 3254, 3357, 3557, 3599, 3971, 4456], 'retinoic': [129, 321, 410], 'acid': [130, 322, 411, 2460], 'or': [132, 324, 502, 523, 1862, 2401, 2596, 2875, 2910, 2952, 2985, 2997, 3054, 3123, 3131, 3153, 3167, 3572, 3602, 3619, 3876, 3911, 4649], 'thyroid': [133, 325, 413], 'Overexpression': [136, 328, 4784, 4802, 5499], 'interacting': [139, 331, 3722, 4361, 4474, 4477], 'hMMS19': [142, 160, 168, 182, 334, 352, 360, 374, 1773, 1786, 2029, 2518, 2570, 2644, 2733, 2763, 2807, 2840, 3063, 3139, 3179, 3252, 3289, 3338, 3355, 3393, 3405, 3415, 3606, 3684, 3709, 3732, 3753, 3769, 3873, 3906, 3955, 3969, 4055, 4075, 4246, 4311, 4369, 4430, 4454, 4480, 4514, 4568, 4639, 4664, 4685, 4695, 4710, 4722, 4744, 4755, 4882, 4906, 4938, 5017, 5083, 5097, 5115, 5131, 5317, 5385, 5403, 5446, 5501, 5520], 'strongly': [143, 335, 2884, 2988, 3469, 3740, 3925, 4056, 4907], 'inhibits': [144, 336, 4787], 'ER-mediated': [145, 162, 337, 354, 3447, 3727, 5503], 'activation,': [147, 339], 'indicating': [148, 340], 'dominant': [150, 342, 3634, 3666, 4799], 'negative': [151, 343, 3635, 3667, 4800], 'activity.': [152, 344, 3585, 3680, 4904], 'In': [153, 345, 2890, 3164, 3371, 3713, 5338, 5459], 'contrast,': [154, 346, 2891, 3165, 3372, 3714], 'over': [155, 347], 'full-length': [159, 351, 2493, 2514, 3056, 3062, 3354, 3369, 3670, 3940, 4770, 4881], 'activation.': [164, 356], 'We': [165, 357, 2531, 2561, 2639, 2926, 3498, 3881, 5529, 5561], 'find': [166, 358], 'stimulates': [169, 361], 'ERα,': [174, 366, 3941, 5539], 'activity,': [179, 371, 3869, 3996], 'suggesting': [180, 372, 1339, 1543, 2795, 3177, 3199, 3336, 3359, 3577, 3751, 3942, 3967, 4073, 4355, 4464], 'may': [183, 375, 1343, 1546, 1787, 3394, 3580, 3607, 3629, 3701, 3756, 3770, 4321, 4358, 4469, 4559, 4569, 4581, 4659, 4727, 5042, 5098, 5331], 'be': [184, 376, 1344, 1593, 3630, 3702, 4322, 4359, 4382, 4442, 4470, 4728, 5043, 5332, 5387, 5407], 'AF-1-specific': [186, 378, 1791, 4261, 4942, 5523], 'steroid/nuclear': [384], 'steroid': [387, 656], 'basic-helix-loop-helix': [392, 1570], 'Per-Arnt-Sim': [393, 1573], 'glutathione': [394, 2190], 'S-transferase': [395], 'hemagglutinin': [396], 'kilobase(s)': [397], 'polyacrylamide': [398], 'gel': [399], 'electrophoresis': [400], '17β-estradiol': [401], 'methyl': [402, 4107], 'methanesulfonate': [403, 4108], 'Ligand': [404], 'binding': [405, 509, 1856, 2240, 2278, 3208, 3250, 3276, 3554, 3899, 4520], '(SNR)1': [419], 'processes': [434], 'such': [435, 977, 1329, 2782, 4955, 5191], 'development': [437, 1641], 'reproduction': [439], '(1Tsai': [440], 'M.J.': [441, 619, 682, 725, 1071, 1171, 1199, 1364, 4035], "O'Malley": [442, 620, 683, 1072, 1093, 1172, 1202, 1367, 5548], 'B.W.': [443, 621, 684, 1073, 1094, 1173, 1203, 1368], 'Annu.': [444], 'Rev.': [445], 'Biochem.': [446], '1994;': [447, 608], '63:': [448], '451-486Crossref': [449], 'PubMed': [450, 483, 563, 585, 611, 634, 669, 689, 715, 734, 754, 777, 800, 829, 861, 887, 925, 953, 1013, 1041, 1078, 1105, 1146, 1186, 1215, 1251, 1274, 1295, 1322, 1380, 1416, 1439, 1490, 1538, 1584, 1625, 1658, 1690, 1706, 1722, 1822, 1934, 2265, 2379, 2487, 2702, 2724, 3810, 3852, 4025, 4047, 4118, 4139, 4156, 4202, 4229, 4294, 4414, 4552, 4630, 4849, 4873, 4987, 5163, 5262, 5308, 5377, 5440], 'Scopus': [451, 484, 564, 586, 612, 635, 670, 690, 716, 735, 755, 778, 801, 830, 862, 888, 926, 954, 1014, 1042, 1079, 1106, 1147, 1187, 1216, 1252, 1275, 1296, 1323, 1381, 1417, 1440, 1491, 1539, 1585, 1626, 1659, 1691, 1707, 1723, 1823, 1935, 2266, 2380, 2488, 2703, 2725, 3811, 3853, 4026, 4048, 4140, 4157, 4203, 4230, 4295, 4415, 4553, 4631, 4850, 4874, 5164, 5263, 5309, 5378, 5441], '(2699)': [452], 'Google': [453, 486, 566, 588, 614, 637, 672, 692, 718, 737, 757, 780, 803, 832, 864, 890, 928, 956, 1016, 1044, 1081, 1108, 1149, 1189, 1218, 1254, 1277, 1298, 1325, 1383, 1419, 1442, 1493, 1541, 1587, 1628, 1661, 1693, 1709, 1725, 1825, 1937, 2268, 2382, 2490, 2705, 2727, 3813, 3855, 4028, 4050, 4119, 4142, 4159, 4205, 4218, 4232, 4297, 4417, 4555, 4633, 4852, 4876, 4988, 5166, 5265, 5311, 5380, 5443], 'Scholar,': [454, 567, 589, 615, 719, 738, 781, 804, 833, 865, 929, 1017, 1082, 1109, 1219, 1255, 1278, 1299, 1384, 1420, 1694, 1710, 2706, 4029, 4143, 4206, 4219, 4853], '2Mangelsdorf': [455], 'D.J.': [456, 1517], 'Thummel': [457], 'C.': [458, 547, 573, 662, 744, 1092, 1227, 1392, 1577, 1679, 2248, 2362, 2689, 4536, 4623], 'Beato': [459], 'M.': [460, 472, 1620, 2472, 3795, 4187, 4839, 4970, 5298], 'Herrlich': [461], 'P.': [462, 470, 474, 555, 577, 597, 746, 1221, 1223, 1309, 1386, 1388, 1698, 2476, 3799, 4191], 'Schutz': [463], 'G.': [464, 818, 1088, 1479, 5152], 'Umesono': [465], 'K.': [466, 698, 723, 1035, 1129, 4964], 'Blumberg': [467], 'B.': [468, 993, 5146], 'Kastner': [469], 'Mark': [471], 'Chambon': [473, 554, 576, 745], 'et': [475], 'al.Cell.': [476], '1995;': [477, 686, 1719, 4411], '83:': [478], '835-839Abstract': [479], 'Full': [480, 560, 582, 856, 858, 882, 884, 948, 950, 1008, 1010, 1210, 1212, 1269, 1271, 1375, 1377, 1434, 1436, 3847, 3849, 4020, 4022, 4042, 4044, 4547, 4549, 4844, 4846, 4868, 4870, 5257, 5259, 5303, 5305, 5372, 5374, 5435, 5437], 'Text': [481, 561, 583, 857, 859, 883, 885, 949, 951, 1009, 1011, 1211, 1213, 1270, 1272, 1376, 1378, 1435, 1437, 3848, 3850, 4021, 4023, 4043, 4045, 4548, 4550, 4845, 4847, 4869, 4871, 5258, 5260, 5304, 5306, 5373, 5375, 5436, 5438], 'PDF': [482, 562, 584, 860, 886, 952, 1012, 1214, 1273, 1379, 1438, 3851, 4024, 4046, 4551, 4848, 4872, 5261, 5307, 5376, 5439], '(6088)': [485], 'Scholar).': [487, 638, 891, 957, 1045, 1150, 1326, 1443, 1494, 1588, 1662, 1726, 1938, 2269, 2383, 2491, 2728, 3856, 4051, 4160, 4233, 4418, 4634, 4877, 5167, 5266, 5312, 5444], 'These': [488, 2912, 3007, 3389, 3586, 5513], 'share': [490, 1560], 'common': [492, 1562], 'structure:': [494], '(AF-1,': [501], 'A/B': [503], 'region),': [504, 513], 'centrally': [506], 'located': [507, 2809], '(or': [511, 2580], 'C': [512], '(AF-2,': [521], 'LBD,': [522], 'E/F': [524], 'domain).': [525], 'together': [531, 2096, 4364], 'to': [532, 898, 1949, 1976, 2022, 2173, 2527, 2657, 3048, 3218, 3251, 3412, 3704, 3725, 3758, 3785, 3820, 3934, 3999, 4103, 4123, 4441, 4482, 4594, 4608, 4645, 4650, 4670, 4797, 4824, 4828, 5034, 5069, 5197, 5334, 5414, 5533], 'regulate': [533, 3786, 3821, 4077], 'cell-type-specific': [538], 'promoter-specific': [540], '(3Tora': [542], 'L.': [543, 571, 845, 937, 985, 1086, 1683, 1714, 2478, 3801, 4111, 4130, 4147, 4193, 4208, 4223, 4399], 'White': [544], 'J.': [545, 750, 783, 787, 808, 876, 989, 1023, 1063, 1084, 1204, 1225, 1369, 1390, 1469, 1718, 2250, 2254, 2364, 2368, 2681, 4036, 4541, 4835, 4974, 5140, 5148, 5294], 'Brou': [546], 'Tasset': [548], 'D.': [549, 569, 595, 841, 933, 1123, 1233, 1398, 2708, 2715, 3829, 4861, 4976, 5239, 5354, 5417], 'Webster': [550], 'N.': [551, 871, 4397], 'Scheer': [552, 574], 'E.': [553, 575, 916, 1239, 1404, 1696, 3833, 5243, 5358, 5421], 'Cell.': [556, 578, 729, 852, 944, 1004, 1265, 1290, 1317, 1430, 1685, 2260, 2374, 2482, 3805, 3843, 4016, 4151, 4197, 4840, 4864, 4982, 5253, 5299, 5368, 5431], '1989;': [557, 4215], '59:': [558], '477-487Abstract': [559], '(889)': [565], '4Tasset': [568], 'Tora': [570], 'Fromental': [572], '1990;': [579], '62:': [580], '1177-1187Abstract': [581], '(297)': [587], '5Tzukerman': [590], 'M.T.': [591], 'Esty': [592], 'A.': [593, 630, 700, 711, 773, 843, 867, 1101, 1125, 1127, 1142, 1182, 1257, 1422, 1534, 1818, 1930, 4008, 4290, 4405], 'Santiso-Mere': [594], 'Danielian': [596], 'Parker': [598, 919, 1287], 'M.G.': [599, 795, 920, 1003, 1135, 1288], 'Stein': [600], 'R.B.': [601], 'Pike': [602], 'J.W.': [603], 'McDonnell': [604], 'D.P.': [605, 1201, 1366], 'Mol.': [606, 728, 1246, 1264, 1289, 1316, 1411, 1429, 1684, 2259, 2373, 2481, 3804, 3842, 4015, 4133, 4150, 4196, 4981, 5252, 5367, 5430], 'Endocrinol.': [607, 1247, 1412], '8:': [609], '21-30Crossref': [610], '(612)': [613], '6McInerney': [616], 'E.M.': [617, 1169], 'Tsai': [618, 679, 681, 1068, 1070, 1170, 1196, 1198, 1361, 1363, 5551], 'Katzenellenbogen': [622, 1174, 1240, 1405], 'B.S.': [623, 1175, 1241, 1406], 'Proc.': [624, 705, 767, 1095, 1136, 1176, 1528, 1812, 1924, 4284], 'Natl.': [625, 706, 768, 1096, 1137, 1177, 1529, 1813, 1925, 4285], 'Acad.': [626, 707, 769, 1097, 1138, 1178, 1530, 1814, 1926, 4286], 'Sci.': [627, 708, 770, 1098, 1139, 1179, 1531, 1815, 1927, 4287], 'U.': [628, 709, 771, 1099, 1140, 1180, 1532, 1816, 1928, 4288], 'S.': [629, 710, 772, 791, 918, 1021, 1100, 1141, 1181, 1237, 1282, 1402, 1533, 1817, 1929, 2470, 2480, 2713, 3793, 3803, 3841, 4113, 4132, 4149, 4185, 4195, 4210, 4221, 4289, 4978, 4980, 5251, 5366, 5429], '1996;': [631, 712, 751, 1005, 1183, 2484, 3807, 4199], '93:': [632, 713, 1184], '10069-10073Crossref': [633, 1185], '(219)': [636, 1188], 'However,': [639, 1727, 4444, 4689, 4731, 5049], 'exact': [641], 'mechanism': [642, 968, 3862, 4992, 5073, 5327], 'currently': [644, 4692], 'unclear.': [645], 'Several': [646], 'coactivators': [648, 896, 976, 1154, 1342, 1559, 1737, 4277, 4952, 5006], 'for': [649, 1851, 1870, 1964, 2161, 2414, 2959, 3019, 3207, 3278, 3542, 3947, 4097, 4583, 4682, 5045, 5537, 5543, 5552, 5558, 5566, 5576], 'SNR': [650], 'have': [651, 3673, 5462], 'been': [652, 1497, 3783, 3818], 'identified,': [653], 'including': [654, 1565, 1610, 2673, 3238], '(SRC)/p160': [659], 'family': [660, 894, 1451], '(9Leo': [661, 1576, 4622], 'Chen': [663, 765, 1028, 1232, 1397, 1578, 1810, 1922, 2257, 2371, 4282, 4539, 4624, 5565, 5574], 'J.D.': [664, 766, 1579, 1811, 1923, 2258, 2372, 4283, 4540, 4625], 'Gene.': [665, 1580, 4626], '2000;': [666, 1102, 1143, 1535, 1581, 2262, 2376, 2699, 3844, 4226, 4544, 4627, 4841, 5160, 5254, 5300, 5369, 5432], '245:': [667, 1582, 4628], '1-11Crossref': [668, 1583, 4629], '(440)': [671, 1586, 4632], 'Scholar),': [673, 693, 758, 1542, 1629, 3814, 4556, 4989, 5381], 'which': [674, 2544, 2655, 3718, 3895, 4388, 4498, 4666, 4774, 5053, 5329], 'contains': [675, 2545, 3642, 3896, 4493], 'SRC-1': [676, 1050, 4435], '(10Oñate': [677], 'S.A.': [678, 1191, 1356], 'S.Y.': [680, 1069, 1197, 1362], 'Science.': [685, 825, 1074, 1486, 4410], '270:': [687, 4412], '1354-1357Crossref': [688], '(2058)': [691], 'GRIP1/TIF2': [694], '(11Hong': [695], 'H.': [696, 721, 748, 762, 835, 1029, 1090, 1301, 1303, 1807, 1919, 2246, 2360, 2696, 4279, 4538, 4855, 4962, 4972], 'Kohli': [697, 722], 'Trivedi': [699], 'Johnson': [701], 'D.L.': [702], 'Stallcup': [703, 726, 1242, 1314, 1407], 'M.R.': [704, 727, 1243, 1315, 1408], '4948-4952Crossref': [714], '(614)': [717], '12Hong': [720], 'Garabedian': [724, 4034], 'Biol.': [730, 877, 1205, 1291, 1318, 1370, 1686, 2261, 2375, 2483, 3806, 4037, 4152, 4198, 4542, 4983], '1997;': [731, 774, 797, 826, 853, 879, 922, 1487, 1703, 1819, 1931, 2721, 4291], '17:': [732], '2735-2744Crossref': [733], '(497)': [736], '13Voegel': [739], 'J.J.': [740], 'Heine': [741], 'M.J.S.': [742], 'Zechel': [743], 'Gronemeyer': [747], 'EMBO': [749, 1717], '15:': [752], '3667-3675Crossref': [753], '(952)': [756], 'RAC3/AIB1/ACTR/pCIP': [760], '(14Li': [761, 1806, 1918, 4278], 'Gomes': [763, 1808, 1920, 4280], 'P.J.': [764, 939, 1245, 1311, 1410, 1809, 1921, 2683, 4281], '94:': [775, 1820, 1932, 4292], '8479-8484Crossref': [776, 1821, 1933, 4293], '(504)': [779, 1824, 1936, 4296], '15Torchia': [782], 'Rose': [784, 998, 1112], 'D.W.': [785, 999, 1113], 'Inostroza': [786], 'Kamei': [788], 'Y.': [789, 849, 983, 1033, 1065, 4831, 4966, 4968, 5290], 'Westin': [790], 'Glass': [792, 1000, 1132], 'C.K.': [793, 1001, 1133], 'Rosenfeld': [794, 1002, 1130, 1134], 'Nature.': [796, 921, 1621], '387:': [798, 923], '677-684Crossref': [799], '(1107)': [802], '16Anzick': [805], 'S.L.': [806, 1467], 'Kononen': [807, 1468], 'Walker': [809, 1026, 1470], 'R.L.': [810, 839, 1471], 'Azorsa': [811, 1472, 1522], 'D.O.': [812, 1473, 1523], 'Tanner': [813, 1474], 'M.M.': [814, 1475], 'Guan': [815, 1476], 'X.Y.': [816, 1477], 'Sauter': [817, 1478], 'Kallioniemi': [819, 1480], 'O.P.': [820, 1481], 'Trent': [821, 1482], 'J.M.': [822, 1483, 3839, 4033, 5154, 5249, 5364, 5427], 'Meltzer': [823, 1484, 1524], 'P.S.': [824, 1485, 1525], '277:': [827, 1488], '965-968Crossref': [828, 1489], '(1432)': [831, 1492], '17Chen': [834], 'Lin': [836, 994, 4856], 'R.J.': [837, 4857], 'Schiltz': [838], 'Chakravarti': [840], 'Nash': [842], 'Nagy': [844], 'Privalsky': [846], 'M.L.': [847, 1681, 1716], 'Nakatani': [848, 1032], 'Evans': [850, 1030, 4862], 'R.M.': [851, 1031, 4863], '90:': [854], '569-580Abstract': [855], '(1268)': [863], '18Takeshita': [866], 'Cardona': [868], 'G.R.': [869], 'Koibuchi': [870], 'Suen': [872], 'C.-S.': [873], 'Chin': [874], 'W.W.': [875], 'Chem.': [878, 1206, 1371, 4038, 4543], '272:': [880], '27629-27634Abstract': [881], '(325)': [889], 'SRC/p160': [893, 1153, 1341, 1450, 1558, 1736, 4276, 4428], 'binds': [897, 4823], 'hydrophobic': [900], 'pocket': [901, 4618], 'on': [902, 3446, 3527, 3547, 3566, 3677, 3860, 3907, 3959, 4808, 4902, 4926, 5132], 'surface': [904, 3277, 4478], 'LBD': [908, 4621], '(19Heery': [913], 'D.M.': [914, 1286], 'Kalkhoven': [915], 'Hoare': [917, 1281], '733-736Crossref': [924], '(1772)': [927], '20Shiau': [930], 'A.K.': [931], 'Barstad': [932], 'Loria': [934], 'P.M.': [935], 'Cheng': [936], 'Kushner': [938, 1244, 1310, 1409], 'Agard': [940], 'D.A.': [941], 'Greene': [942, 5536], 'G.L.': [943], '1998;': [945, 1038, 1075, 1207, 1248, 1372, 1413, 1687], '95:': [946], '927-937Abstract': [947], '(2255)': [955], 'via': [966, 4615, 4640], 'involving': [969], 'histone': [970], 'acetylation': [971], 'recruitment': [973, 5411], 'additional': [975], 'CBP/p300': [979], 'P/CAF': [981], '(21Kamei': [982], 'Xu': [984], 'Heinzel': [986], 'T.': [987, 1119, 3831, 5136, 5241, 5356, 5419], 'Torchia': [988], 'Kurokawa': [990], 'R.': [991, 1131, 2687], 'Gloss': [992], 'S.C.': [995], 'Heyman': [996], 'R.A.': [997, 1307, 5142], '85:': [1006], '403-414Abstract': [1007], '(1926)': [1015], '22Blanco': [1018], 'J.C.': [1019, 2679], 'Minucci': [1020], 'Lu': [1022], 'Yang': [1024], 'X.J.': [1025], 'K.K.': [1027], 'Ozato': [1034], 'Genes': [1036, 1701], 'Dev.': [1037, 1654, 1702], '12:': [1039, 1249, 1414], '1638-1651Crossref': [1040], '(340)': [1043], 'Genetic': [1046], 'studies': [1047], 'demonstrate': [1048], '(pCIP)': [1053], 'involved': [1055, 1345, 2827, 3229, 4323, 4471, 5388, 5408], 'regulating': [1057, 1552, 3614, 3867, 5046, 5347], 'hormonal': [1058], 'responses': [1059], 'mice': [1061], '(23Xu': [1062], 'Qiu': [1064], 'DeMayo': [1066], 'F.J.': [1067], '279:': [1076], '1922-1925Crossref': [1077], '(597)': [1080], '24Xu': [1083], 'Liao': [1085], 'Ning': [1087], 'Yoshida-Komiya': [1089], 'Deng': [1091], '97:': [1103, 1144, 1536], '6379-6384Crossref': [1104], '(458)': [1107], '25Wang': [1110], 'Z.': [1111], 'Hermanson': [1114], 'O.': [1115], 'Liu': [1116], 'F.': [1117, 1261, 1284, 1426, 2719, 4012], 'Herman': [1118], 'Wu': [1120, 2251, 2365], 'W.': [1121, 1229, 1394, 4859, 5144], 'Szeto': [1122], 'Gleiberman': [1124], 'Krones': [1126], 'Pratt': [1128], '13549-13554Crossref': [1145], '(170)': [1148], 'interact': [1156, 2423, 2895, 2907, 3181, 3291, 3340, 3396, 4433, 4457, 4570, 4697, 4745], 'several': [1162, 2670, 2779, 4557, 5188], 'SNRs': [1163], '(6McInerney': [1168], 'Scholar,26Onate': [1190], 'Boonyaratanakornkit': [1192, 1357], 'V.': [1193, 1263, 1358, 1428, 4014], 'Spencer': [1194, 1359], 'T.E.': [1195, 1360], 'Edwards': [1200, 1365], '273:': [1208, 1373], '12101-12108Abstract': [1209, 1374], '(347)': [1217, 1382], '27Webb': [1220, 1385], 'Nguyen': [1222, 1230, 1387, 1395], 'Shinsako': [1224, 1389], 'Anderson': [1226, 1391], 'Feng': [1228, 1393], 'M.P.': [1231, 1396, 4403], 'Huang': [1234, 1304, 1399], 'S.M.': [1235, 1305, 1400], 'Subramanian': [1236, 1401], 'McKinerney': [1238, 1403], '1605-1618Crossref': [1250, 1415], '(0)': [1253, 1418], '28Tremblay': [1256, 1421], 'Tremblay': [1258, 1423, 4009], 'G.B.': [1259, 1424, 4010], 'Labrie': [1260, 1425, 4011], 'Giguere': [1262, 1427, 4013], '1999;': [1266, 1292, 1319, 1431, 1655, 4017, 4039, 4865, 4984], '3:': [1267, 1432, 4018], '513-519Abstract': [1268, 1433, 4019], '(388)': [1276, 1441, 4027], '29Bevan': [1279], 'C.L.': [1280], 'Claessens': [1283], 'Heery': [1285], '19:': [1293, 1320, 4985], '8383-8392Crossref': [1294], '(334)': [1297], '30Ma': [1300], 'Hong': [1302], 'Irvine': [1306], 'Webb': [1308], 'Coetzee': [1312], 'G.A.': [1313], '6164-6173Crossref': [1321], '(214)': [1324], 'For': [1327, 2211, 4566], 'ERβ,': [1328, 5545], 'interaction': [1330, 1675, 2838, 3021, 3027, 3112, 3362, 3593, 4335, 4344, 4367, 4379, 4502, 4580, 5401], 'regulated': [1332], 'phosphorylation': [1334, 4001, 4586, 5272, 5450], 'region,': [1338], 'cross-talk': [1347], 'between': [1348, 4368], '(26Onate': [1355], '(AIB1)': [1445, 1501], 'unique': [1447, 5003], 'among': [1448, 1605, 4426, 5004], 'coactivators,': [1453, 4429], 'because': [1454, 2519, 3639], 'overexpressed': [1459], 'subset': [1462], 'cancers': [1465], '(16Anzick': [1466], 'It': [1495, 3646, 4674], 'has': [1496, 2636, 3782, 3817, 4805, 4899, 4923], 'demonstrated': [1498, 4760], 'activators': [1502], 'form': [1503, 4660], 'stable': [1505], 'ERα': [1508, 3316, 3343, 3398, 3466, 3508, 3827, 3883, 3909, 3912, 3931, 3965, 3977, 3994, 4004, 4522], 'MCF-7': [1510], 'cells': [1513, 2186, 2304, 2322, 2330, 2386, 2738, 3691, 4101], '(31Tikkanen': [1514], 'M.K.': [1515], 'Carter': [1516], 'Harris': [1518], 'A.M.': [1519, 4401], 'Le': [1520], 'H.M.': [1521], 'Murdoch': [1526], 'F.E.': [1527], '12536-12540Crossref': [1537], '(38)': [1540], 'play': [1547, 3608], 'important': [1549, 1670, 3611, 5044, 5342], 'role': [1550, 1671, 3612, 4172, 5129, 5343], 'ER': [1553, 3528, 3536, 3553, 3583, 3615, 3624, 3678, 3686, 3736, 3868, 4078, 4256, 4530, 4572, 4589, 4599, 4701, 4716, 4749, 4757, 4780, 4793, 4822, 4888, 4903, 4913, 5335, 5352, 5392, 5415, 5452], 'vivo.': [1556], 'structure,': [1564], 'highly': [1567, 1603, 4424], '(bHLH)': [1571], '(PAS)': [1574], 'domains': [1575, 1802, 3015, 4450, 4468, 4681], 'PAS': [1590, 4375, 4394, 4421, 4449, 4460, 4467, 4505, 4643, 5021, 5038], 'can': [1592, 3180, 3339, 3520, 4076, 4380, 4696], 'subdivided': [1594, 2947, 3882], 'into': [1595, 1846, 1863, 2054, 2069, 2948, 3884], 'A': [1596, 3460], 'B': [1598], 'regions.': [1599], 'This': [1600, 2816, 4579], 'severalDrosophila': [1606], 'mammalian': [1608], 'proteins,': [1609, 4453], 'Per,': [1611], 'Sim,': [1612, 4463], 'Arnt': [1614], '(32Huang': [1615], 'Z.J.': [1616], 'Edery': [1617], 'I.': [1618, 1677, 4031], 'Rosbash': [1619], '1993;': [1622], '364:': [1623], '259-262Crossref': [1624], '(416)': [1627], 'well': [1631, 2332, 2776], 'many': [1634], 'circadian': [1637], 'rhythm': [1638], 'neural': [1640], '(for': [1642], 'review,': [1644], 'see': [1645], 'Ref.': [1646], '33Crews': [1647], 'S.T.': [1648], 'Fan': [1649], 'C.M.': [1650], 'Curr.': [1651], 'Opin.': [1652], 'Genet.': [1653, 4135], '9:': [1656], '580-587Crossref': [1657], '(159)': [1660], 'bHLH-PAS': [1664, 1732, 1766, 2426, 2898, 2934, 2942, 3133, 4267, 4314], 'ofDrosophila': [1666, 2608], 'proteins': [1667, 1859, 1875, 2180, 2197, 2421], 'plays': [1668, 4170], 'mediating': [1673], 'protein-protein': [1674, 1981, 4325, 4378], '(34Pongratz': [1676], 'Antonsson': [1678], 'Whitelaw': [1680, 1715], 'Poellinger': [1682, 1713], '18:': [1688], '4079-4088Crossref': [1689], '(91)': [1692, 4158], '35Zelzer': [1695], 'Wappner': [1697], 'Shilo': [1699], 'B.Z.': [1700], '11:': [1704], '2079-2089Crossref': [1705], '(124)': [1708], '36Lindebro': [1711], 'M.C.': [1712], '14:': [1720, 2722], '3528-3539Crossref': [1721], '(163)': [1724], 'remains': [1738, 4440], 'largely': [1739, 4306, 4997, 5062], 'unknown.': [1740, 4307, 4998], 'report': [1743], 'identification': [1745, 5315], 'protein': [1757, 1995, 2220, 2231, 2285, 3671, 4316, 4386, 5204, 5323], 'isolated': [1758, 1961, 4236], 'two-hybrid': [1762, 1911, 2433, 2857, 2924, 3265, 3387], 'screening': [1763, 1912, 1985, 2434], 'bait.': [1771, 2440], 'ERs': [1777, 3409, 3597, 4726, 5013], 'manner.': [1781, 3476, 4528], 'Our': [1782, 5080], 'data': [1783, 2450, 2913, 3008, 3258, 3390, 3587, 5514], 'suggest': [1784, 3009, 3391, 3767, 4936, 5383], 'ER.': [1795, 3421, 3763, 3777, 4088, 4265, 4595, 4688, 4945, 5398, 5512], 'fragments': [1798, 1843, 3047], 'encoding': [1799], 'various': [1800, 1974, 2735, 2852, 3044], 'Scholar)': [1826, 4120], 'were': [1827, 1844, 1885, 1960, 1969, 2129, 2139, 2181, 2198, 2305, 2323, 2387, 2406, 2602, 3064, 3348, 3381, 3512, 4953], 'polymerase': [1830, 1837, 1897, 5212, 5274], 'chain': [1831, 1898], 'reaction': [1832, 1899], 'Pfu': [1835], '(Stratagene,': [1838], 'Inc.).': [1839, 1957, 2046], 'subcloned': [1845, 2053, 2068], 'pGBT9': [1847], 'vector': [1848, 1866], '(CLONTECH,': [1849, 1956, 2045], 'Inc.),': [1850], 'Gal4': [1854], 'domain-RAC3': [1857], 'fusion': [1858, 1874, 2179, 2219, 3042, 3125, 3352], 'yeast,': [1861], 'pGEX-2T': [1865], '(Amersham': [1867, 2193], 'Pharmacia': [1868, 2194], 'Biotech)': [1869], 'GST': [1873, 2178, 2212, 3037, 3041, 3098, 3122, 3124, 3152, 3298, 3351], 'Escherichia': [1877], 'coli.': [1878], 'polylinker': [1880], 'regions': [1881, 2593], 'these': [1883, 1893, 2617, 2971, 3257, 3711, 4564], 'constructs': [1884, 1894, 2128], 'confirmed': [1886, 2130], 'sequencing.': [1889, 2133], 'Detail': [1890], 'information': [1891], 'primers': [1900], 'used': [1901, 1946, 2021], 'this': [1903, 2001, 2563, 2665, 2753, 3005, 3424, 3640, 3699, 3960, 4303, 4319, 4439, 4491, 5109], 'study': [1904, 5066], 'available': [1906], 'upon': [1907], 'request.': [1908], 'was': [1913, 1945, 1997, 2020, 2050, 2063, 2074, 2106, 2149, 2158, 2221, 2272, 2281, 2286, 2296, 2349, 2497, 2667, 2767, 2946, 3077, 3085, 3119, 3141, 3914, 5219, 5269], 'conducted': [1914, 2431], 'described': [1916, 2244, 2357], 'previously': [1917, 2243], 'Briefly,': [1939], 'pGBT-RAC3-N': [1941], '(amino': [1942], 'acids': [1943, 2509], '1–408)': [1944], 'bait': [1948, 2873], 'screen': [1950, 4096], 'placenta': [1953], 'cDNA': [1954, 2030, 2036, 2494, 2536], 'library': [1955], 'Positive': [1958], 'clones': [1959], 'tested': [1963, 1972, 2845, 2958, 3287, 3916], 'β-galactosidase': [1965, 2417], 'expression.': [1966], 'Library': [1967], 'plasmids': [1968], 'recovered': [1970], 'baits': [1975, 2853, 2972], 'confirm': [1977, 2914, 3025], 'specificity': [1978, 2847], 'interactions.': [1982, 4565], 'clone': [1986, 2084, 2123, 2443, 2537, 2650], '2.1': [1987], '(RS2.1)': [1988], 'showed': [1989, 2444, 3248], 'homology': [1990, 2464, 2584], 'further': [1998, 2835, 5065], 'analyzed': [1999, 2298, 2774, 3088, 3142, 3439], 'study.': [2002], 'MMS19-specific': [2005], 'primer': [2006, 2041], '(CAT': [2007], 'AAG': [2008], 'ATA': [2009], 'GGA': [2010], 'GAT': [2011], 'CTG': [2012, 2018], 'GCT': [2013], 'GGG': [2014], 'CAC': [2015], 'CCA': [2016], 'AGA': [2017], 'TC)': [2019], 'amplify': [2023], 'extreme': [2025], '5′-end': [2026], 'from': [2031, 2042, 2118, 2605, 5286], 'HeLa': [2033], 'cell': [2034, 2772, 2812, 5457], 'Marathon-ready': [2035], 'along': [2037], 'adaptor': [2040], 'manufacturer': [2044], 'resultant': [2048], 'product': [2049], 're-amplified': [2051], 'pBluescript': [2055], 'II': [2056, 5213, 5275], 'SK+': [2057], 'sequenced.': [2059], 'RS2.1': [2061, 2102, 2442, 2455, 2496, 2515, 2849, 2863, 2881, 2892, 2916, 2962, 2982, 3052, 3059, 3114, 3445, 3479, 3526, 3539, 3543, 3562, 3579, 3595, 3628, 3650, 3661, 4766, 4786, 4804], 'insert': [2062], 'released': [2064], 'SalI/BglII': [2066], 'pCMX-HA': [2071], 'vector.': [2072], 'pCMX-HA-hMMS19mt': [2073, 2113], 'constructed': [2075], 'assembling': [2077], 'theSalI/BglII': [2078], 'fragment': [2079, 2088, 2099, 2111, 2117, 2145, 3053, 3060, 3641, 4767], 'longest': [2082], 'RACE': [2083], 'BglII/NsiI': [2087], 'GenBank™': [2090, 2540], 'accession': [2091, 2125, 2652], 'number': [2092, 2542, 2653], 'AF007151': [2093], '(Research': [2094], 'Genetics)': [2095], 'aSalI/NsiI': [2098], 'clone.': [2103], 'pCMX-HA-hMMS19': [2105], 'obtained': [2107, 3349], 'replacing': [2109], 'theDra3/NsiI': [2110], 'same': [2116], 'expressed': [2120, 2182], 'sequence': [2121, 2526], 'tag': [2122], 'BE206052(GenBank': [2124], 'number).': [2126], 'All': [2127], 'Multiple': [2134], 'Tissue': [2135], 'Northern': [2136, 2729], 'blots': [2137], '(CLONTECH)': [2138], 'probed': [2140], 'a32P-labeled': [2142], 'NsiI/BglII': [2143], '1.5-kb': [2144], 'hMMS19.': [2147, 3057, 3209, 3279], 'Hybridization': [2148], 'performed': [2150, 2350, 3035, 3427], 'using': [2151, 2205, 2351, 3040], 'ExpressHyb': [2153], 'solution': [2154], '(CLONTECH).': [2155], 'blot': [2157, 2730], 'washed': [2159, 2273, 2388], 'twice': [2160], '20': [2162], 'min': [2163], '2×': [2165], 'SSC/0.1%': [2166], 'SDS': [2167, 2289], 'at': [2168, 2175, 2235, 2328, 2549, 2557, 2588, 2626, 3501], 'room': [2169], 'temperature': [2170], 'subjected': [2172], 'autoradiography': [2174, 3146], '−70': [2176], '°C.': [2177], 'inE.': [2183], 'coli': [2184], 'BL-21': [2185], 'purified': [2188], 'agarose': [2191], 'beads': [2192], 'Biotech).': [2195], '35S-Labeled': [2196], 'made': [2199], 'vitro': [2202, 2228, 3111], 'transcription/translation': [2203], 'reactions': [2204], 'T7-Quick': [2207], 'reticulocyte': [2208, 3071], 'lysate': [2209], '(Promega).': [2210], 'pull-down': [2213, 3038, 3299], 'assay,': [2214], '5': [2215, 2224, 3693, 3749], 'μg': [2216], 'bead-conjugated': [2218], 'incubated': [2222, 3078, 3120], 'μl': [2225], 'translated': [2229], '35S-labeled': [2230], 'moderate': [2233, 3696], 'shaking': [2234], '4': [2236, 2745, 3575], '°C': [2237], 'overnight': [2238], 'buffer': [2241, 2291], '(37Li': [2245, 2359], 'Leo': [2247, 2361], 'Zhu': [2249, 2363], 'X.': [2252, 2366, 4833, 5292], "O'Neil": [2253, 2367], 'Park': [2255, 2369], 'E.J.': [2256, 2370], '20:': [2263, 2377], '1784-1796Crossref': [2264, 2378], '(307)': [2267, 2381], 'pellet': [2271], 'four': [2274], 'times': [2275], 'buffer.': [2279], 'Supernatant': [2280], 'removed,': [2282], 'bound': [2284, 3083, 3138], 'eluted': [2287, 3086], 'sample': [2290], 'boiling.': [2293], 'then': [2297, 2927, 3915, 4636, 4668], 'SDS-PAGE': [2300, 3090, 3144], 'autoradiography.': [2302, 3092], 'HEK293': [2303, 3435, 3690], 'maintained': [2306], "Dulbecco's": [2308, 2336], 'modified': [2309, 2337], "Eagle's": [2310, 2338], 'medium': [2311, 2339, 2396], 'supplemented': [2312, 2340], '10%': [2314, 2342], 'fetal': [2315, 2345], 'bovine': [2316, 2346], 'serum.': [2317, 2347], 'One': [2318], 'day': [2319], 'before': [2320, 2358], 'transfection,': [2321, 2385], 'seeded': [2324], '12-well': [2326], 'plates': [2327], '50,000': [2329], 'per': [2331], 'phenol-red': [2334], 'free': [2335], 'charcoal': [2343], 'resin-stripped': [2344], 'Transfection': [2348], 'standard': [2353], 'calcium/phosphate': [2354], 'method': [2355], 'After': [2384], 'phosphate-buffered': [2390], 'saline': [2391], 're-fed': [2393], 'fresh': [2395], 'containing': [2397], 'either': [2398], 'vehicle': [2399, 2402], 'alone': [2400, 2864, 2973, 3747], 'plus': [2403], 'ligands.': [2404], 'Cells': [2405], 'lysed': [2407], '24': [2408], 'h': [2409], 'after': [2410], 'treatment': [2411], 'assayed': [2413], 'luciferase': [2415, 3452, 3471], 'activities.': [2418], 'To': [2419, 2834, 3024, 3422, 3857], 'RAC3,': [2429, 2842], 'RAC3-N-terminal': [2437], 'strongest': [2445], 'interaction.': [2446, 3232, 4326], 'Sequence': [2447], 'analysis': [2448, 2731, 4328], 'base': [2451], 'search': [2452], 'revealed': [2453, 2739], 'encodes': [2456], '164-amino': [2459], 'polypeptide': [2461], 'shares': [2463], '(38Lauder': [2469, 3792, 4184], 'Bankmann': [2471, 3794, 4186], 'Guzder': [2473, 3796, 4188], 'S.N.': [2474, 3797, 4189], 'Sung': [2475, 3798, 4190], 'Prakash': [2477, 2479, 3800, 3802, 4112, 4131, 4146, 4148, 4192, 4194, 4209, 4222], '16:': [2485, 3808, 4200], '6783-6793Crossref': [2486, 3809, 4201], '(53)': [2489, 3812, 4204], 'obtained,': [2498], 'predicts': [2501], 'open': [2503], 'reading': [2504], 'frame': [2505], '1030': [2507], 'amino': [2508, 2559], '(Fig.': [2510, 2747, 2938, 2954, 3147, 3321, 3574, 3692, 3748], '1': [2511, 2748], 'A).': [2512, 2860, 3323, 3694], 'named': [2517], 'related': [2522], 'size': [2524, 2751], 'MMS19.': [2530], 'found': [2533, 2641, 2805, 3303, 3499, 4383], 'mutant': [2535, 2556, 2565, 4894], '(accession': [2541], 'AF007151),': [2543], 'single': [2547, 2741], 'deletion': [2548], 'nucleotide': [2550, 4174, 5182], '2240,': [2551], 'resulting': [2552], 'truncation': [2555, 2564, 4893], '779': [2558], 'acids.': [2560], 'designate': [2562], 'hMMS19-mt.': [2567], 'Comparison': [2568], 'shows': [2575, 4518], '36%': [2577], 'overall': [2578], 'similarity': [2579], '26%': [2581], 'identity).': [2582], 'most': [2586, 4271, 5531], 'striking': [2587], 'N-': [2590, 2628], '61%': [2595], '57%': [2597], 'similarities,': [2598], 'respectively.': [2599], 'Related': [2600], 'sequences': [2601, 2618], 'predicted': [2604], 'genomes': [2607], 'melanogaster,': [2609], 'Caenorhabditis': [2610], 'elegans,': [2611], 'Arabidopsis': [2613], 'thaliana.': [2614], 'Alignment': [2615], 'indicates': [2619], 'through': [2624, 4338, 4392, 5493], 'evolution': [2625], 'domains,': [2631, 3892], 'whereas': [2632, 2992, 4891], 'central': [2634], 'region': [2635, 2666, 2931, 3226, 4273, 4492], 'diverged': [2637], 'significantly.': [2638], 'resides': [2646], 'genomic': [2649], '(RP11–445I23,': [2651], 'AL359388),': [2654], 'maps': [2656, 4481], 'chromosome': [2658], '10q24.': [2659], 'loss': [2661], 'heterozygosity': [2663], 'observed': [2668], 'cancers,': [2672], 'endometrial': [2674], 'prostate': [2676], 'carcinomas': [2677], '(39Alers': [2678], 'Rochat': [2680], 'Krijtenburg': [2682], 'Hop': [2684], 'W.C.': [2685], 'Kranse': [2686], 'Rosenberg': [2688], 'Tanke': [2690], 'H.J.': [2691], 'Schroder': [2692], 'F.H.': [2693], 'van': [2694], 'Dekken': [2695], 'Lab.': [2697], 'Invest.': [2698], '80:': [2700], '931-942Crossref': [2701], '(157)': [2704], '40Cappellen': [2707], 'Gil': [2709], 'Diez': [2710], 'de': [2711], 'Medina': [2712], 'Chopin': [2714], 'Thiery': [2716], 'J.P.': [2717], 'Radvanyi': [2718], 'Oncogene.': [2720], '3059-3066Crossref': [2723], '(105)': [2726], 'transcript': [2742], 'about': [2744, 3514], 'kb': [2746], 'B,top).': [2749], 'message': [2754], 'agreement': [2757], 'length': [2760], 'cDNA.': [2764], 'hMMS19transcript': [2766], 'detected': [2768], 'all': [2770], 'lines': [2773], 'tissues': [2781], 'heart,': [2784], 'brain,': [2785], 'placenta,': [2786], 'liver,': [2787], 'skeletal': [2788], 'muscle,': [2789], 'kidney': [2791], '(data': [2792, 2977, 3253, 3356, 3556], 'shown),': [2794, 3358], 'hMMS19is': [2797], 'ubiquitously': [2798], 'expressed.': [2799], 'Furthermore,': [2800, 3559, 3729, 5267], 'indirect': [2802], 'immunofluorescence,': [2803], 'nucleus': [2813], '(Fig.1': [2814], 'C).': [2815, 3532, 3921], 'localization': [2818], 'consistent': [2820, 3260, 3383, 3589, 4817], 'hypothesis': [2823], 'regulation.': [2833], 'analyze': [2836], 'first': [2844, 4573], 'interactions': [2850, 2960, 3374, 3403, 4332, 4512, 4683, 4720], 'assay': [2858, 3039, 3430], '(Fig.2': [2859, 3107], 'As': [2861, 2967, 3093, 3150, 3463, 3922, 3975, 4878], 'expected,': [2862, 2968, 3094, 3151, 3464, 3923, 3976, 4879], 'did': [2865, 2871, 2893, 2905, 2999, 3155], 'activate': [2867, 3001], 'reporter': [2868, 2886, 2975, 2990, 3002, 3428, 3453, 3491, 3551, 4794, 4889], 'nor': [2870, 2904], 'RAC3-N': [2874, 2883, 2920, 2986], 'other': [2876, 3234, 5005, 5570], 'unrelated': [2877], 'baits.': [2878], 'Coexpression': [2879, 2980], 'activated': [2885, 2974, 2989, 3470, 3926], 'expected.': [2889], 'mouse': [2901], 'Sim2': [2902], '(Sim-N)': [2903], 'RARα': [2909, 3571, 3601], 'p53.': [2911], 'specifically': [2918], 'assay.': [2925, 2966, 3006, 3300], 'mapped': [2928], 'RS2.1-interacting': [2930], 'within': [2932], '2': [2939, 2955, 3148], 'B).': [2940, 3462], 'bHLH,': [2949, 2995, 3127], 'PAS-A,': [2950, 2996, 3128], 'PAS-B,': [2951, 3129, 4354], 'F)': [2956], 'similar': [2965, 3217, 3297], 'none': [2969], 'shown).': [2979, 3255, 3558], 'each': [2987, 3169, 3745, 3893, 4772, 5177], 'expression,': [2991], 'coexpression': [2993, 3517, 3730], 'PAS-B': [2998, 3014, 3186, 3206], 'PAS-A': [3012, 3184, 3204, 4352], 'both': [3017, 3342, 3465, 3507, 4061, 4249, 4351, 4713, 4915, 5012], 'required': [3018, 3946, 5068], 'strong': [3020, 4343, 4519], 'RS2.1.': [3023], 'RS2.1/hMMS19': [3029], 'vitro,': [3033], 'pull': [3049], 'down': [3050, 3101, 3158, 3171, 3191, 3212, 3307, 3328], 'the35S-labeled': [3051], 'transcribed/translated': [3065], 'labeled': [3067], '[35S]methionine': [3069], 'lysate.': [3072], 'First,': [3073, 3437], '35S-RS2.1': [3075, 3106], 'probe': [3076, 3084, 3140], 'GST-RAC3-N,': [3080, 3095], 'alone,': [3099], 'pulled': [3100, 3170, 3190, 3211, 3306, 3327], 'significant': [3103, 3195, 3309, 3330], 'amount': [3104, 3161, 3174, 3196, 3214, 3331], 'C),': [3108], 'confirming': [3109, 3222, 5126], 'RAC3-N.': [3116], 'Second,': [3117], '35S-hMMS19': [3118, 3216], 'PAS-A/B,': [3130], 'RAC3.': [3136, 4371, 4508, 5015], 'D).': [3149], 'GST-bHLH': [3154], 'bring': [3157], 'detectable': [3160], '35S-hMMS19.': [3163], 'GST-PAS-A': [3166], 'GST-PAS-B': [3168], 'noticeable': [3173], '35S-hMMS19,': [3176, 3198], 'weakly': [3182], 'separately.': [3187], 'GST-PAS-A/B': [3189], 'much': [3193], 'more': [3194, 3610, 3739], 'synergistic': [3201], 'effect': [3202, 3524, 3546, 3565, 3636, 3676, 3697, 3902, 3958, 4807, 4901, 4925], 'GST-RAC3-N': [3210], 'GST-PAS-A/B,': [3221], 'bHLH': [3225], 'fragments,': [3237], 'receptor-interacting': [3241], 'domain,': [3247, 3723], 'no': [3249, 3545, 3564, 3957, 4806, 4900, 4924], 'Therefore,': [3256, 4934, 5313], 'above': [3263, 3402, 3765], 'results': [3266, 3347], 'implicating': [3268, 3604], 'Because': [3280, 4419, 4529, 5016], 'receptors,': [3285], 'whether': [3288, 3414, 3872, 4694], 'could': [3290, 3416], 'Intriguingly,': [3301, 3778, 4245, 4905], 'GST-RS2.1': [3305, 3325, 3376], 'fraction': [3310], '(about': [3311], '20%': [3312], 'input)': [3314], '3': [3322], 'Similarly,': [3324], 'ERβ': [3333, 3468, 3510, 4524], '(Fig.3': [3334], 'B),': [3335, 3750], 'ERβ.': [3345, 3400], 'Similar': [3346], 'occur': [3364], 'context': [3367], 'little': [3373], '35S-hRARα': [3378], 'hTRβ': [3380], 'detected,': [3382], 'data.': [3388], 'prompted': [3410], 'us': [3411], 'investigate': [3413], 'modulate': [3417], 'test': [3423], 'possibility,': [3425], 'transient': [3432, 3918], 'transfection': [3433, 3919, 4782], 'cells.': [3436, 3712], 'effects': [3441], 'overexpression': [3443, 3560, 3682, 3904, 4762], 'driven': [3455], 'ER-responsive': [3457], 'elements': [3458], '(Fig.4,': [3459], 'E2-dependent': [3475], 'Cotransfection': [3477, 3953], 'significantly': [3480, 4775], 'reduced': [3481, 3513], 'transactivation': [3484], 'dose-dependent': [3487], 'without': [3489], 'affecting': [3490, 4181], 'absence': [3495, 3985, 4063, 4576, 4814, 4917], 'E2.': [3497], 'that,': [3500], 'highest': [3503], 'concentration': [3504], 'RS2.1,': [3506, 3638], 'activities': [3511, 5190], '8-fold.': [3515], 'Importantly,': [3516], 'reverse': [3521], 'inhibitory': [3523], '(Fig.4': [3531], 'inhibition': [3534, 3622], 'specific,': [3541], 'had': [3544, 3563, 3956, 3979], 'otherwise': [3549], 'identical': [3550], 'lacking': [3552, 4895], 'sites': [3555], 'TRβ': [3573], 'D),': [3576], 'selectively': [3581], 'affect': [3582, 4776], 'preferential': [3592], 'TRβ,': [3603], 'than': [3617, 3741, 3938], 'RAR': [3618], 'TR.': [3620], 'explained': [3631], 'RAC3/ER-interacting': [3644, 4897, 5480], 'possible': [3648, 4735], 'interferes': [3651], 'assembly': [3654], 'functional': [3657], 'ER-coactivator': [3658], 'complex.': [3659], 'If': [3660], 'indeed': [3662], 'acts': [3663], 'mutant,': [3668, 3717], 'should': [3672], 'positive': [3675], 'Indeed,': [3681], 'enhanced': [3685, 3735, 3992, 4057], 'transcription': [3687, 3787, 3927, 4178, 4885, 5056, 5180], 'enhancement': [3700], 'due': [3703, 3998, 4796], 'high': [3705], 'levels': [3706], 'endogenous': [3708], 'hMMS19-mt': [3716], 'lacks': [3719], 'failed': [3724], 'coactivate': [3726], 'transcription.': [3728, 4656], 'synergize': [3757], 'stimulate': [3759], 'findings': [3766], 'shown': [3784, 3819, 5220, 5270], 'influencing': [3789], 'TFIIH': [3790, 3816, 4182, 4592, 5133, 5168, 5186, 5231, 5330, 5345, 5396, 5413, 5475], '(41Chen': [3828, 5238, 5353, 5416], 'Riedl': [3830, 5240, 5355, 5418], 'Washbrook': [3832, 5242, 5357, 5420], 'Pace': [3834, 5244, 5359, 5422], 'P.E.': [3835, 5245, 5360, 5423], 'Coombes': [3836, 5246, 5361, 5424], 'R.C.': [3837, 5247, 5362, 5425], 'Egly': [3838, 5153, 5248, 5363, 5426], 'Ali': [3840, 5250, 5365, 5428], '6:': [3845, 5255, 5370, 5433], '127-137Abstract': [3846, 5256, 5371, 5434], '(250)': [3854, 5264, 5379, 5442], 'shed': [3858], 'light': [3859, 5339], 'examined': [3871], 'affects': [3874], 'hERα.': [3880], '(Fig.5': [3920], 'E2': [3924, 3990, 4067], 'lesser': [3936], 'extent': [3937], 'maximal': [3948], 'ERα.': [3952], 'AF-2,': [3966], 'AF-2-dependent': [3973], 'coactivator.': [3974], 'constitutive': [3981], 'ligand.': [3987, 4578], 'Addition': [3988], 'slightly': [3991], 'presumably': [3997], 'E2-mediated': [4000], '(28Tremblay': [4007], '42Rogatsky': [4030], 'Trowbridge': [4032], '274:': [4040], '22296-22302Abstract': [4041], '(153)': [4049], 'cotransfection': [4053], 'presence': [4065, 4349, 4919], '6.0-': [4069], '2.5-fold,': [4071], 'respectively,': [4072], 'stimulating': [4082], 'MMS19was': [4089], 'initially': [4090], 'identified': [4091, 5463], 'genetic': [4095], 'mutations': [4098], 'render': [4100], 'sensitive': [4102], 'alkylating': [4105], 'agent': [4106], '(MMS)': [4109], '(43Prakash': [4110], 'Genetics.': [4114], '1977;': [4115], '86:': [4116], '33-55Crossref': [4117], 'later': [4122], 'UV': [4124], 'cross-linking': [4127], 'agents': [4128], '(44Prakash': [4129], 'Gen.': [4134], '1979;': [4136], '176:': [4137], '351-359Crossref': [4138], '(48)': [4141], '45Miller': [4144], 'R.D.': [4145], '1982;': [4153], '2:': [4154], '939-948Crossref': [4155], 'Analysis': [4161, 4509], 'mutation': [4164], 'suggests': [4167, 4317, 4489, 4717, 5095, 5324], 'excision': [4175, 5183], 'regulation': [4179, 5390], '46Prakash': [4207], 'Ann.': [4211], 'Ist.': [4212], 'Super.': [4213], 'Sanita.': [4214], '25:': [4216], '99-113PubMed': [4217], '47Prakash': [4220], 'Mutat.': [4224], 'Res.': [4225, 5159], '451:': [4227], '13-24Crossref': [4228], '(284)': [4231], 'functions': [4258, 4939, 5101], 'Scholar);': [4298], 'however,': [4299], 'isolation': [4309], 'domain-interacting': [4315], 'Further': [4327], 'hMMS19-RAC3': [4331], 'reveals': [4333], 'region.': [4341], 'occurs': [4345], 'only': [4346, 4947], 'there': [4357], 'two': [4360], 'interfaces': [4362], 'stabilize': [4365, 4646], 'involvement': [4373], 'theDrosophila': [4385], 'Period,': [4387], 'Timeless': [4391], 'its': [4393, 4483], '(48Gekakis': [4396], 'Saez': [4398], 'Delahaye-Brown': [4400], 'Myers': [4402], 'Sehgal': [4404], 'Young': [4406], 'M.W.': [4407], 'Weitz': [4408], 'C.J.': [4409], '811-815Crossref': [4413], '(312)': [4416], 'might': [4431, 4499, 5386, 5406, 5447], 'and/or': [4436], 'TIF2,': [4437], 'tested.': [4443], 'despite': [4445], 'conservation': [4447], 'different': [4452, 4466, 4473, 4737], 'does': [4455], 'proteins.': [4475], 'Structural': [4487], 'prediction': [4488], 'multiple': [4494], 'potential': [4495, 4950], 'amphipathic': [4496], 'helices,': [4497], 'mediate': [4500], '(49Leo': [4535], 'Li': [4537], '275:': [4545], '5976-5982Abstract': [4546], '(37)': [4554], 'possibilities': [4558], 'explain': [4560], 'relevance': [4562, 4753], 'instance,': [4567, 4584], 'modulate,': [4582], 'states': [4587], 'targeting': [4591], 'Upon': [4596], 'ligand': [4597, 4829, 4921], 'binding,': [4598], 'undergoes': [4600], 'conformational': [4602], 'change': [4603], 'allows': [4605], 'bind': [4609], 'LXXLL': [4611], 'motifs': [4612, 4738], 'coactivator-binding': [4617], 'signal': [4651], 'subsequent': [4653], 'event': [4654], 'Alternatively,': [4657, 5445], 'first,': [4665], 'recruited': [4669, 5333], 'liganded': [4672, 4687], 'clear': [4676], 'uses': [4679], 'separate': [4680], 'unknown': [4693], 'simultaneously.': [4702], 'fact': [4704], 'mutually': [4729], 'exclusive.': [4730], 'equally': [4734], 'independently.': [4750], 'physiological': [4752], 'signaling': [4758], 'hMMS19,': [4771], 'assays.': [4783], 'effect.': [4801], 'basal': [4809], 'promoter': [4810], 'ligand,': [4816], 'observation': [4820], 'chromatin': [4825], 'response': [4827], '(50Shang': [4830, 5289], 'Hu': [4832, 5291], 'DiRenzo': [4834, 5293], 'Lazar': [4836, 5295], 'M.A.': [4837, 5296], 'Brown': [4838, 5297], '103:': [4842, 5301], '843-852Abstract': [4843, 5302], '(1452)': [4851, 5310], '51Chen': [4854], 'Xie': [4858], 'Wilpitz': [4860], '98:': [4866], '675-686Abstract': [4867], '(563)': [4875], 'gene,': [4890], 'separated': [4931], 'Currently,': [4946], 'few': [4949], 'reported,': [4954], 'p68': [4958], 'RNA': [4959], 'helicase': [4960], '(7Endoh': [4961], 'Maruyama': [4963], 'Masuhiro': [4965], 'Kobayashi': [4967], 'Goto': [4969], 'Tai': [4971], 'Yanagisawa': [4973], 'Metzger': [4975], 'Hashimoto': [4977], 'Kato': [4979], '5363-5372Crossref': [4986], 'regulates': [5026], 'ER,': [5030], 'intriguing': [5033], 'speculate': [5035], 'function.': [5048], 'mechanisms': [5051], 'activates': [5055], 'synergizes': [5058], 'unknown,': [5063], 'fully': [5070], 'understand': [5071], 'receptors.': [5079], 'finding': [5081], 'bridge': [5099], 'During': [5106], 'preparation': [5107], 'manuscript,': [5110], 'another': [5111], 'group': [5112], 'reported': [5113], 'directly': [5117], 'XPD': [5120, 5198], 'XPB': [5122, 5200], 'subunits': [5123], 'TFIIH,': [5125], 'regulatory': [5128], '(8Seroz': [5135], 'Winkler': [5137], 'G.S.': [5138], 'Auriol': [5139], 'Verhage': [5141], 'Vermeulen': [5143], 'Smit': [5145], 'Brouwer': [5147], 'Eker': [5149], 'A.P.': [5150], 'Weeda': [5151], 'Hoeijmakers': [5155], 'J.H.': [5156], 'Nucleic': [5157], 'Acids': [5158], '28:': [5161], '4506-4513Crossref': [5162], '(23)': [5165], 'multiprotein': [5171], 'consisting': [5173], 'nine': [5175], 'subunits,': [5176], 'participating': [5178], 'pathways.': [5185], 'harbors': [5187], 'enzymatic': [5189], 'DNA-dependent': [5194], 'ATPase': [5195], 'linked': [5196], 'cdk-activating': [5203], 'kinase,': [5205], 'cyclin-dependent': [5207, 5232], 'kinase': [5208, 5233], 'phosphorylates': [5210], 'tail': [5215, 5277], 'Recently,': [5217], 'hERα': [5226], 'phosphorylated': [5228], 'precedes': [5279], 'dissociation': [5281], 'ER/p160': [5283], 'target': [5287, 5336], 'promoters': [5288, 5455], 'ER-': [5320], 'novel': [5326, 5517], 'promoters.': [5337], 'bridging': [5395], 'Possibly,': [5399], 'facilitate': [5448], 'TFIIH-mediated': [5449], 'specific': [5454], 'types.': [5458], 'summary,': [5460], 'characterized': [5465], 'evolutionarily': [5495], 'modulates': [5502], 'enhancing': [5507], 'reveal': [5515], 'grateful': [5532], 'Dr.': [5534, 5540], 'Geoffrey': [5535], 'Jan-Ake': [5541], 'Gustafsson': [5542], 'rat': [5544], 'Drs.': [5546], 'Bert': [5547], 'Ming-Jer': [5550], 'ERE-E1A-Luc': [5553], 'reporter,': [5554], 'Peter': [5556], 'Moffett': [5557], 'mSim2': [5559], 'constructs.': [5560], 'thank': [5563], 'Amy': [5564], 'technical': [5567], 'assistance': [5568], 'members': [5571], 'laboratory': [5575], 'helpful': [5577], 'discussion.': [5578]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1994839764', 'counts_by_year': [{'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2024-12-13T03:03:38.170065', 'created_date': '2016-06-24'}
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