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'We': [17], 'previously': [18], 'reported': [19], 'the': [21, 44, 65, 122, 152, 179, 188, 194, 212, 220], 'HCV': [22, 84, 209, 233], 'nonstructural': [23], 'protein': [24, 30], '5A': [25], '(NS5A)': [26], 'bound': [27], 'to': [28, 215], 'cellular': [29], 'FKBP38': [31, 98, 101, 185], 'and': [32, 60, 77, 83, 97, 134, 173, 224, 235], 'resulted': [33], 'in': [34, 37, 62, 64, 81, 118], 'apoptosis': [35, 149, 217], 'suppression': [36], 'human': [38], 'hepatoma': [39], 'cell': [40], 'line': [41], 'Huh7.': [42], 'In': [43], 'present': [45], 'research': [46], 'we': [47], 'further': [48], 'found': [49], 'NS5A': [51, 73, 89, 96, 130, 142, 147, 163, 177, 183, 210], 'increased': [52], 'phosphorylation': [53, 79], 'levels': [54], 'of': [55, 67, 95, 127, 196], 'two': [56], 'mTOR-targeted': [57], 'substrates,': [58], 'S6K1': [59, 76], '4EBP1,': [61], 'Huh7': [63], 'absence': [66], 'serum.': [68], 'mTOR': [69, 92, 105, 123, 153, 165, 213, 223], 'inhibitor': [70, 115], 'rapamycin': [71], 'or': [72, 100, 144, 184], 'knockdown': [74, 102, 143], 'blocked': [75], '4EBP1': [78], 'increase': [80], 'NS5A-Huh7': [82, 119], 'replicon': [85], 'cells,': [86], 'suggesting': [87], 'specifically': [90, 150], 'regulated': [91], 'activation.': [93], 'Overexpression': [94], 'mutants': [99, 186], 'revealed': [103], 'this': [104, 191], 'activation': [106, 124], 'was': [107, 125, 139, 199], 'dependent': [108, 200], 'on': [109, 201], 'NS5A-FKBP38': [110, 168, 202], 'interaction.': [111, 169], 'Phosphatidylinositol': [112], '3-kinase': [113], '(PI3K)': [114], 'LY294002': [116], 'treatment': [117], 'showed': [120, 175], 'independent': [126], 'PI3K.': [128], 'Moreover,': [129], 'suppressed': [131], 'caspase': [132], '3': [133], 'poly(ADP-ribose)': [135], 'polymerase': [136], 'activation,': [137], 'which': [138, 226], 'abolished': [140], 'by': [141, 162], 'rapamycin,': [145], 'indicating': [146], 'inhibited': [148], 'through': [151, 218], 'pathway.': [154], 'Further': [155], 'analyses': [156], 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