Title: Quality of life as a measure of rehabilitation outcome in patients with multiple sclerosis
Abstract: Acta Neurologica ScandinavicaVolume 93, Issue 4 p. 229-235 Quality of life as a measure of rehabilitation outcome in patients with multiple sclerosis A. Jønsson, Corresponding Author A. Jønsson MS-Clinic, Department of Neurology, Rigshospitalet, Rigshospitalet and Multiple Sclerosis Rehabilitation Hospital, Haslev, Denmark.Agnete Jønsson, MS Clinic, Dept of Neurology 2081, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, DenmarkSearch for more papers by this authorJ. Dock, J. Dock Multiple Sclerosis Rehabilitation Hospital, Rigshospitalet and Multiple Sclerosis Rehabilitation Hospital, Haslev, Denmark.Search for more papers by this authorM. H. Ravnborg, M. H. Ravnborg Department of Clinical Neurophysiology, Rigshospitalet and Multiple Sclerosis Rehabilitation Hospital, Haslev, Denmark.Search for more papers by this author A. Jønsson, Corresponding Author A. Jønsson MS-Clinic, Department of Neurology, Rigshospitalet, Rigshospitalet and Multiple Sclerosis Rehabilitation Hospital, Haslev, Denmark.Agnete Jønsson, MS Clinic, Dept of Neurology 2081, Rigshospitalet, Blegdamsvej 9, DK-2100 Copenhagen, DenmarkSearch for more papers by this authorJ. Dock, J. Dock Multiple Sclerosis Rehabilitation Hospital, Rigshospitalet and Multiple Sclerosis Rehabilitation Hospital, Haslev, Denmark.Search for more papers by this authorM. H. Ravnborg, M. H. Ravnborg Department of Clinical Neurophysiology, Rigshospitalet and Multiple Sclerosis Rehabilitation Hospital, Haslev, Denmark.Search for more papers by this author First published: April 1996 https://doi.org/10.1111/j.1600-0404.1996.tb00512.xCitations: 42AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Abstract A total of 43 patients with multiple sclerosis (MS) consecutively admitted to the Multiple Sclerosis Rehabilitation Hospital in Haslev completed a Danish version of the Laman & Lankhorst Questionnaire (LLQ) on quality of life (qol), and the Beck Depression Inventory (BDI). Twenty-one of the 43 pts completed the questionnaires at discharge as well. All patients received the standard multidiciplinary rehabilitative treatment. The purpose was to evaluate the LLQ as a measure of qol and as an outcome measure. The 43 MS-patients had low weighted qol scores on the following items: readily tired, fatigue, dependence on other people, worry about deterioration and walk. Correspondingly, the BDI showed high scores on fatigability, work difficulty and somatic preoccupation. The correlation between LLQ and BDI was statistically significant (0.54, p<0002), but weak. ANOVA with repeated measures (LLQ and BDI at admission and discharge) was applied to evaluate rehabilitation outcome in 21 patients. LLQ: The patients experienced a significant reduction in disability on fatigue and mood; and in the importance of being able to climb stairs and to work. The weighted qol-scores increased significantly on physical endurance, work and mood. BDI scores showed a significant decrease on pessimism, irritability, loss of libido and total BDI-score. The changes measured by the LLQ were mainly on behavioral aspects. As the correlation coefficient was only 0.54, the LLQ and the BDI seem to address different aspects of quality of life. References 1 Jønsson A, Korfitzen EM, Heltberg A, Ravnborg HM, Byskov-Ottosen E. Effect of neuropsychological treatment in patients with multiple sclerosis. Acta Neurol Scand 1993: 88: 394– 400. 2 Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Arch Gen Psychiatry 1961: 4: 561– 71. 3 Beck AT. manual 1987. 4 Laman H, Lankhorst G j. Subjective weighting of disability: an approach to quality og life assesment in rehabilitation. Disabil Rehab 1994: 16: 198– 204. 5 Kurtzke JF. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology 1983: 33: 1445– 52. 6 Schumacher GA, Beebe G, Kibler R f, et al. Problems of experimental trials of therapy in multiple sclerosis: Report by the panel on the evaluation of experimental trials of therapy in multiple sclerosis. Ann N Y Acad Sci 1965: 122: 522– 68. 7 Badley EM. An introduction to the concepts and classifications of the international classification og impairments, disabilities, and handicaps. Disabil Rehab 1993: 15: 161– 178. 8 Millon T. Millon clinical multiaxial inventory-II. National Computer System, Inc. Minneapolis , USA 1987. Citing Literature Volume93, Issue4April 1996Pages 229-235 ReferencesRelatedInformation