Publication Information

{'id': 'https://openalex.org/W1994091239', 'doi': 'https://doi.org/10.1101/gr.4.6.357', 'title': 'Oligonucleotides with fluorescent dyes at opposite ends provide a quenched probe system useful for detecting PCR product and nucleic acid hybridization.', 'display_name': 'Oligonucleotides with fluorescent dyes at opposite ends provide a quenched probe system useful for detecting PCR product and nucleic acid hybridization.', 'publication_year': 1995, 'publication_date': '1995-06-01', 'ids': {'openalex': 'https://openalex.org/W1994091239', 'doi': 'https://doi.org/10.1101/gr.4.6.357', 'mag': '1994091239', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/7580930'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1101/gr.4.6.357', 'pdf_url': 'http://genome.cshlp.org/content/4/6/357.full.pdf', 'source': {'id': 'https://openalex.org/S43092948', 'display_name': 'Genome Research', 'issn_l': '1088-9051', 'issn': ['1088-9051', '1549-5469'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315909', 'host_organization_name': 'Cold Spring Harbor Laboratory Press', 'host_organization_lineage': ['https://openalex.org/P4310315909'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'http://genome.cshlp.org/content/4/6/357.full.pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5055590197', 'display_name': 'Kenneth J. Livak', 'orcid': 'https://orcid.org/0000-0001-9105-5856'}, 'institutions': [{'id': 'https://openalex.org/I4210108796', 'display_name': 'Agave BioSystems (United States)', 'ror': 'https://ror.org/01gfdf281', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210108796']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'K J Livak', 'raw_affiliation_strings': ['Applied Biosystems Division, Foster City, California 94404, USA.'], 'affiliations': [{'raw_affiliation_string': 'Applied Biosystems Division, Foster City, California 94404, USA.', 'institution_ids': ['https://openalex.org/I4210108796']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5108513669', 'display_name': 'Samantha Flood', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210108796', 'display_name': 'Agave BioSystems (United States)', 'ror': 'https://ror.org/01gfdf281', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210108796']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'S J Flood', 'raw_affiliation_strings': ['Applied Biosystems Division, Foster City, California 94404, USA.'], 'affiliations': [{'raw_affiliation_string': 'Applied Biosystems Division, Foster City, California 94404, USA.', 'institution_ids': ['https://openalex.org/I4210108796']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027090976', 'display_name': 'J Marmaro', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210108796', 'display_name': 'Agave BioSystems (United States)', 'ror': 'https://ror.org/01gfdf281', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210108796']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'J Marmaro', 'raw_affiliation_strings': ['Applied Biosystems Division, Foster City, California 94404, USA.'], 'affiliations': [{'raw_affiliation_string': 'Applied Biosystems Division, Foster City, California 94404, USA.', 'institution_ids': ['https://openalex.org/I4210108796']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5075307067', 'display_name': 'W. G. Giusti', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210108796', 'display_name': 'Agave BioSystems (United States)', 'ror': 'https://ror.org/01gfdf281', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210108796']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'W Giusti', 'raw_affiliation_strings': ['Applied Biosystems Division, Foster City, California 94404, USA.'], 'affiliations': [{'raw_affiliation_string': 'Applied Biosystems Division, Foster City, California 94404, USA.', 'institution_ids': ['https://openalex.org/I4210108796']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5045721305', 'display_name': 'K Deetz', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210108796', 'display_name': 'Agave BioSystems (United States)', 'ror': 'https://ror.org/01gfdf281', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I4210108796']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'K Deetz', 'raw_affiliation_strings': ['Applied Biosystems Division, Foster City, California 94404, USA.'], 'affiliations': [{'raw_affiliation_string': 'Applied Biosystems Division, Foster City, California 94404, USA.', 'institution_ids': ['https://openalex.org/I4210108796']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 11.272, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 1619, 'citation_normalized_percentile': {'value': 0.999967, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '4', 'issue': '6', 'first_page': '357', 'last_page': '362'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10207', 'display_name': 'Advanced biosensing and bioanalysis techniques', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10207', 'display_name': 'Advanced biosensing and bioanalysis techniques', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11048', 'display_name': 'Bacteriophages and microbial interactions', 'score': 0.9965, 'subfield': {'id': 'https://openalex.org/subfields/2303', 'display_name': 'Ecology'}, 'field': {'id': 'https://openalex.org/fields/23', 'display_name': 'Environmental Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T11393', 'display_name': 'Biosensors and Analytical Detection', 'score': 0.9965, 'subfield': {'id': 'https://openalex.org/subfields/2204', 'display_name': 'Biomedical Engineering'}, 'field': {'id': 'https://openalex.org/fields/22', 'display_name': 'Engineering'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/molecular-beacon', 'display_name': 'Molecular beacon', 'score': 0.6246154}, {'id': 'https://openalex.org/keywords/nucleic-acid-detection', 'display_name': 'Nucleic acid detection', 'score': 0.5172149}, {'id': 'https://openalex.org/keywords/oligomer-restriction', 'display_name': 'Oligomer restriction', 'score': 0.4746949}, {'id': 'https://openalex.org/keywords/nucleic-acid-quantitation', 'display_name': 'Nucleic acid quantitation', 'score': 0.4103194}], 'concepts': [{'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.8719119}, {'id': 'https://openalex.org/C24107716', 'wikidata': 'https://www.wikidata.org/wiki/Q123619', 'display_name': 'Nucleic acid', 'level': 2, 'score': 0.8054447}, {'id': 'https://openalex.org/C129312508', 'wikidata': 'https://www.wikidata.org/wiki/Q133686', 'display_name': 'Oligonucleotide', 'level': 3, 'score': 0.79416615}, {'id': 'https://openalex.org/C91881484', 'wikidata': 'https://www.wikidata.org/wiki/Q191807', 'display_name': 'Fluorescence', 'level': 2, 'score': 0.6407004}, {'id': 'https://openalex.org/C119203544', 'wikidata': 'https://www.wikidata.org/wiki/Q425891', 'display_name': 'Molecular beacon', 'level': 4, 'score': 0.6246154}, {'id': 'https://openalex.org/C2910367586', 'wikidata': 'https://www.wikidata.org/wiki/Q348667', 'display_name': 'Nucleic acid detection', 'level': 3, 'score': 0.5172149}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.4915224}, {'id': 'https://openalex.org/C111824103', 'wikidata': 'https://www.wikidata.org/wiki/Q7086828', 'display_name': 'Oligomer restriction', 'level': 4, 'score': 0.4746949}, {'id': 'https://openalex.org/C54871578', 'wikidata': 'https://www.wikidata.org/wiki/Q2074275', 'display_name': 'Nucleic acid thermodynamics', 'level': 4, 'score': 0.43083054}, {'id': 'https://openalex.org/C126307556', 'wikidata': 'https://www.wikidata.org/wiki/Q4227909', 'display_name': 'Nucleic acid quantitation', 'level': 3, 'score': 0.4103194}, {'id': 'https://openalex.org/C552990157', 'wikidata': 'https://www.wikidata.org/wiki/Q7430', 'display_name': 'DNA', 'level': 2, 'score': 0.37474892}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.335761}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.32838345}, {'id': 'https://openalex.org/C3017666073', 'wikidata': 'https://www.wikidata.org/wiki/Q1764062', 'display_name': 'Base sequence', 'level': 3, 'score': 0.2193037}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C62520636', 'wikidata': 'https://www.wikidata.org/wiki/Q944', 'display_name': 'Quantum mechanics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000199', 'descriptor_name': 'Actins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D009693', 'descriptor_name': 'Nucleic Acid Hybridization', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D009838', 'descriptor_name': 'Oligodeoxyribonucleotides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D016133', 'descriptor_name': 'Polymerase Chain Reaction', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D000199', 'descriptor_name': 'Actins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001483', 'descriptor_name': 'Base Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017931', 'descriptor_name': 'DNA Primers', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004259', 'descriptor_name': 'DNA-Directed DNA Polymerase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005456', 'descriptor_name': 'Fluorescent Dyes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007202', 'descriptor_name': 'Indicators and Reagents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008274', 'descriptor_name': 'Magnesium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015345', 'descriptor_name': 'Oligonucleotide Probes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016133', 'descriptor_name': 'Polymerase Chain Reaction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019914', 'descriptor_name': 'Taq Polymerase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1101/gr.4.6.357', 'pdf_url': 'http://genome.cshlp.org/content/4/6/357.full.pdf', 'source': {'id': 'https://openalex.org/S43092948', 'display_name': 'Genome Research', 'issn_l': '1088-9051', 'issn': ['1088-9051', '1549-5469'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315909', 'host_organization_name': 'Cold Spring Harbor Laboratory Press', 'host_organization_lineage': ['https://openalex.org/P4310315909'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/7580930', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1101/gr.4.6.357', 'pdf_url': 'http://genome.cshlp.org/content/4/6/357.full.pdf', 'source': {'id': 'https://openalex.org/S43092948', 'display_name': 'Genome Research', 'issn_l': '1088-9051', 'issn': ['1088-9051', '1549-5469'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315909', 'host_organization_name': 'Cold Spring Harbor Laboratory Press', 'host_organization_lineage': ['https://openalex.org/P4310315909'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Clean water and sanitation', 'id': 'https://metadata.un.org/sdg/6', 'score': 0.44}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 8, 'referenced_works': ['https://openalex.org/W1988966853', 'https://openalex.org/W1989252766', 'https://openalex.org/W1992423407', 'https://openalex.org/W1999814206', 'https://openalex.org/W2070721758', 'https://openalex.org/W2082183799', 'https://openalex.org/W2094517427', 'https://openalex.org/W2135883841'], 'related_works': ['https://openalex.org/W4232058268', 'https://openalex.org/W2159402811', 'https://openalex.org/W2143058064', 'https://openalex.org/W2132796188', 'https://openalex.org/W2123714202', 'https://openalex.org/W2086263373', 'https://openalex.org/W2066089379', 'https://openalex.org/W2046499511', 'https://openalex.org/W2026710381', 'https://openalex.org/W1985024341'], 'abstract_inverted_index': {'K': [0, 11], 'J': [1, 4, 6], 'Livak,': [2], 'S': [3], 'Flood,': [5], 'Marmaro,': [7], 'W': [8], 'Giusti,': [9], 'and': [10], 'Deetz': [12], 'Applied': [13], 'Biosystems': [14], 'Division,': [15], 'Foster': [16], 'City,': [17], 'California': [18], '94404,': [19], 'USA.': [20]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1994091239', 'counts_by_year': [{'year': 2024, 'cited_by_count': 8}, {'year': 2023, 'cited_by_count': 10}, {'year': 2022, 'cited_by_count': 13}, {'year': 2021, 'cited_by_count': 24}, {'year': 2020, 'cited_by_count': 15}, {'year': 2019, 'cited_by_count': 22}, {'year': 2018, 'cited_by_count': 19}, {'year': 2017, 'cited_by_count': 18}, {'year': 2016, 'cited_by_count': 30}, {'year': 2015, 'cited_by_count': 36}, {'year': 2014, 'cited_by_count': 53}, {'year': 2013, 'cited_by_count': 46}, {'year': 2012, 'cited_by_count': 46}], 'updated_date': '2025-01-06T10:28:52.999149', 'created_date': '2016-06-24'}