Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1993229549', 'doi': 'https://doi.org/10.1074/jbc.m110.103606', 'title': 'The TRPV4 Channel Contributes to Intercellular Junction Formation in Keratinocytes', 'display_name': 'The TRPV4 Channel Contributes to Intercellular Junction Formation in Keratinocytes', 'publication_year': 2010, 'publication_date': '2010-06-01', 'ids': {'openalex': 'https://openalex.org/W1993229549', 'doi': 'https://doi.org/10.1074/jbc.m110.103606', 'mag': '1993229549', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/20413591', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2881798'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1074/jbc.m110.103606', 'pdf_url': 'http://www.jbc.org/article/S0021925819575810/pdf', 'source': {'id': 'https://openalex.org/S140251998', 'display_name': 'Journal of Biological Chemistry', 'issn_l': '0021-9258', 'issn': ['0021-9258', '1067-8816', '1083-351X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'http://www.jbc.org/article/S0021925819575810/pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5030676954', 'display_name': 'Takaaki Sokabe', 'orcid': 'https://orcid.org/0000-0003-1280-9424'}, 'institutions': [{'id': 'https://openalex.org/I200475212', 'display_name': 'The Graduate University for Advanced Studies, SOKENDAI', 'ror': 'https://ror.org/0516ah480', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I200475212']}, {'id': 'https://openalex.org/I199525922', 'display_name': 'National Institutes of Natural Sciences', 'ror': 'https://ror.org/055n47h92', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I1319490839', 'https://openalex.org/I199525922']}, {'id': 'https://openalex.org/I4210097088', 'display_name': 'Okazaki Institute for Integrative Bioscience', 'ror': 'https://ror.org/00v3cq569', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I4210097088']}, {'id': 'https://openalex.org/I4210145863', 'display_name': 'National Institute for Physiological Sciences', 'ror': 'https://ror.org/048v13307', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I1319490839', 'https://openalex.org/I199525922', 'https://openalex.org/I4210145863']}], 'countries': ['JP'], 'is_corresponding': True, 'raw_author_name': 'Takaaki Sokabe', 'raw_affiliation_strings': ['Department of Physiological Sciences, The Graduate University for Advanced Studies (Sokendai), Okazaki 444-8585, Japan', 'Division of Cell Signaling, Okazaki Institute for Integrative Bioscience, National Institute for Physiological Sciences, National Institutes of Natural Sciences, Okazaki 444-8787'], 'affiliations': [{'raw_affiliation_string': 'Department of Physiological Sciences, The Graduate University for Advanced Studies (Sokendai), Okazaki 444-8585, Japan', 'institution_ids': ['https://openalex.org/I200475212']}, {'raw_affiliation_string': 'Division of Cell Signaling, Okazaki Institute for Integrative Bioscience, National Institute for Physiological Sciences, National Institutes of Natural Sciences, Okazaki 444-8787', 'institution_ids': ['https://openalex.org/I199525922', 'https://openalex.org/I4210097088', 'https://openalex.org/I4210145863']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5070938853', 'display_name': 'Tomoko Fukumi‐Tominaga', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I200475212', 'display_name': 'The Graduate University for Advanced Studies, SOKENDAI', 'ror': 'https://ror.org/0516ah480', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I200475212']}, {'id': 'https://openalex.org/I199525922', 'display_name': 'National Institutes of Natural Sciences', 'ror': 'https://ror.org/055n47h92', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I1319490839', 'https://openalex.org/I199525922']}, {'id': 'https://openalex.org/I4210097088', 'display_name': 'Okazaki Institute for Integrative Bioscience', 'ror': 'https://ror.org/00v3cq569', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I4210097088']}, {'id': 'https://openalex.org/I4210145863', 'display_name': 'National Institute for Physiological Sciences', 'ror': 'https://ror.org/048v13307', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I1319490839', 'https://openalex.org/I199525922', 'https://openalex.org/I4210145863']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Tomoko Fukumi-Tominaga', 'raw_affiliation_strings': ['Department of Physiological Sciences, The Graduate University for Advanced Studies (Sokendai), Okazaki 444-8585, Japan', 'Division of Cell Signaling, Okazaki Institute for Integrative Bioscience, National Institute for Physiological Sciences, National Institutes of Natural Sciences, Okazaki 444-8787'], 'affiliations': [{'raw_affiliation_string': 'Department of Physiological Sciences, The Graduate University for Advanced Studies (Sokendai), Okazaki 444-8585, Japan', 'institution_ids': ['https://openalex.org/I200475212']}, {'raw_affiliation_string': 'Division of Cell Signaling, Okazaki Institute for Integrative Bioscience, National Institute for Physiological Sciences, National Institutes of Natural Sciences, Okazaki 444-8787', 'institution_ids': ['https://openalex.org/I199525922', 'https://openalex.org/I4210097088', 'https://openalex.org/I4210145863']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103154970', 'display_name': 'Shigenobu Yonemura', 'orcid': 'https://orcid.org/0000-0002-9357-1448'}, 'institutions': [], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Shigenobu Yonemura', 'raw_affiliation_strings': ['Laboratory of Cellular Morphogenesis, RIKEN Center for Developmental Biology, Kobe 650-0047, Japan'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Cellular Morphogenesis, RIKEN Center for Developmental Biology, Kobe 650-0047, Japan', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5090827612', 'display_name': 'Atsuko Mizuno', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I146500386', 'display_name': 'Jichi Medical University', 'ror': 'https://ror.org/010hz0g26', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I146500386']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Atsuko Mizuno', 'raw_affiliation_strings': ['Department of Pharmacology, Jichi Medical School, Minamikawachi 329-0498, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmacology, Jichi Medical School, Minamikawachi 329-0498, Japan', 'institution_ids': ['https://openalex.org/I146500386']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5074653699', 'display_name': 'Makoto Tominaga', 'orcid': 'https://orcid.org/0000-0003-3111-3772'}, 'institutions': [{'id': 'https://openalex.org/I200475212', 'display_name': 'The Graduate University for Advanced Studies, SOKENDAI', 'ror': 'https://ror.org/0516ah480', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I200475212']}, {'id': 'https://openalex.org/I199525922', 'display_name': 'National Institutes of Natural Sciences', 'ror': 'https://ror.org/055n47h92', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I1319490839', 'https://openalex.org/I199525922']}, {'id': 'https://openalex.org/I4210097088', 'display_name': 'Okazaki Institute for Integrative Bioscience', 'ror': 'https://ror.org/00v3cq569', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I4210097088']}, {'id': 'https://openalex.org/I4210145863', 'display_name': 'National Institute for Physiological Sciences', 'ror': 'https://ror.org/048v13307', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I1319490839', 'https://openalex.org/I199525922', 'https://openalex.org/I4210145863']}], 'countries': ['JP'], 'is_corresponding': True, 'raw_author_name': 'Makoto Tominaga', 'raw_affiliation_strings': ['Department of Physiological Sciences, The Graduate University for Advanced Studies (Sokendai), Okazaki 444-8585, Japan', 'Division of Cell Signaling, Okazaki Institute for Integrative Bioscience, National Institute for Physiological Sciences, National Institutes of Natural Sciences, Okazaki 444-8787'], 'affiliations': [{'raw_affiliation_string': 'Department of Physiological Sciences, The Graduate University for Advanced Studies (Sokendai), Okazaki 444-8585, Japan', 'institution_ids': ['https://openalex.org/I200475212']}, {'raw_affiliation_string': 'Division of Cell Signaling, Okazaki Institute for Integrative Bioscience, National Institute for Physiological Sciences, National Institutes of Natural Sciences, Okazaki 444-8787', 'institution_ids': ['https://openalex.org/I199525922', 'https://openalex.org/I4210097088', 'https://openalex.org/I4210145863']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 5, 'corresponding_author_ids': ['https://openalex.org/A5030676954', 'https://openalex.org/A5074653699'], 'corresponding_institution_ids': ['https://openalex.org/I200475212', 'https://openalex.org/I199525922', 'https://openalex.org/I4210097088', 'https://openalex.org/I4210145863', 'https://openalex.org/I200475212', 'https://openalex.org/I199525922', 'https://openalex.org/I4210097088', 'https://openalex.org/I4210145863'], 'apc_list': {'value': 2500, 'currency': 'USD', 'value_usd': 2500, 'provenance': 'doaj'}, 'apc_paid': {'value': 2500, 'currency': 'USD', 'value_usd': 2500, 'provenance': 'doaj'}, 'fwci': 4.7, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 182, 'citation_normalized_percentile': {'value': 0.999341, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '285', 'issue': '24', 'first_page': '18749', 'last_page': '18758'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11204', 'display_name': 'Calcium Signaling and Ion Channels in Sensation', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2809', 'display_name': 'Sensory Systems'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11204', 'display_name': 'Calcium Signaling and Ion Channels in Sensation', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2809', 'display_name': 'Sensory Systems'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11480', 'display_name': 'Structure and Function of Gap Junctions and Connexins', 'score': 0.9851, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10473', 'display_name': 'Factors Influencing Fruit Ripening and Quality', 'score': 0.9291, 'subfield': {'id': 'https://openalex.org/subfields/1110', 'display_name': 'Plant Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/trpv4', 'display_name': 'TRPV4', 'score': 0.69411945}, {'id': 'https://openalex.org/keywords/trp-channels', 'display_name': 'TRP Channels', 'score': 0.582602}, {'id': 'https://openalex.org/keywords/thermosensation', 'display_name': 'Thermosensation', 'score': 0.509527}], 'concepts': [{'id': 'https://openalex.org/C79879829', 'wikidata': 'https://www.wikidata.org/wiki/Q5571762', 'display_name': 'Intracellular', 'level': 2, 'score': 0.7334209}, {'id': 'https://openalex.org/C90420996', 'wikidata': 'https://www.wikidata.org/wiki/Q15324120', 'display_name': 'TRPV4', 'level': 4, 'score': 0.69411945}, {'id': 'https://openalex.org/C127162648', 'wikidata': 'https://www.wikidata.org/wiki/Q16858953', 'display_name': 'Channel (broadcasting)', 'level': 2, 'score': 0.6421807}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.5886386}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.5352676}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.52731794}, {'id': 'https://openalex.org/C158157758', 'wikidata': 'https://www.wikidata.org/wiki/Q232438', 'display_name': 'Gap junction', 'level': 3, 'score': 0.47092313}, {'id': 'https://openalex.org/C2777074287', 'wikidata': 'https://www.wikidata.org/wiki/Q1473931', 'display_name': 'Keratinocyte', 'level': 3, 'score': 0.4151554}, {'id': 'https://openalex.org/C155164980', 'wikidata': 'https://www.wikidata.org/wiki/Q304043', 'display_name': 'Transient receptor potential channel', 'level': 3, 'score': 0.27797782}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.24537188}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.18229899}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.16460812}, {'id': 'https://openalex.org/C76155785', 'wikidata': 'https://www.wikidata.org/wiki/Q418', 'display_name': 'Telecommunications', 'level': 1, 'score': 0.16161555}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D007365', 'descriptor_name': 'Intercellular Junctions', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D015603', 'descriptor_name': 'Keratinocytes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D050916', 'descriptor_name': 'TRPV Cation Channels', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000199', 'descriptor_name': 'Actins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000199', 'descriptor_name': 'Actins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D000199', 'descriptor_name': 'Actins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019556', 'descriptor_name': 'COS Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002118', 'descriptor_name': 'Calcium', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002118', 'descriptor_name': 'Calcium', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D002118', 'descriptor_name': 'Calcium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002450', 'descriptor_name': 'Cell Communication', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002522', 'descriptor_name': 'Chlorocebus aethiops', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003599', 'descriptor_name': 'Cytoskeleton', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D003599', 'descriptor_name': 'Cytoskeleton', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007365', 'descriptor_name': 'Intercellular Junctions', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015603', 'descriptor_name': 'Keratinocytes', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D015603', 'descriptor_name': 'Keratinocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008954', 'descriptor_name': 'Models, Biological', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009994', 'descriptor_name': 'Osmolar Concentration', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050916', 'descriptor_name': 'TRPV Cation Channels', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013696', 'descriptor_name': 'Temperature', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051176', 'descriptor_name': 'beta Catenin', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D051176', 'descriptor_name': 'beta Catenin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1074/jbc.m110.103606', 'pdf_url': 'http://www.jbc.org/article/S0021925819575810/pdf', 'source': {'id': 'https://openalex.org/S140251998', 'display_name': 'Journal of Biological Chemistry', 'issn_l': '0021-9258', 'issn': ['0021-9258', '1067-8816', '1083-351X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2881798', 'pdf_url': 'https://europepmc.org/articles/pmc2881798?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881798', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/20413591', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1074/jbc.m110.103606', 'pdf_url': 'http://www.jbc.org/article/S0021925819575810/pdf', 'source': {'id': 'https://openalex.org/S140251998', 'display_name': 'Journal of Biological Chemistry', 'issn_l': '0021-9258', 'issn': ['0021-9258', '1067-8816', '1083-351X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 61, 'referenced_works': ['https://openalex.org/W1495055348', 'https://openalex.org/W1545384325', 'https://openalex.org/W1549243184', 'https://openalex.org/W1744742580', 'https://openalex.org/W1965945862', 'https://openalex.org/W1971964944', 'https://openalex.org/W1979288110', 'https://openalex.org/W1980059877', 'https://openalex.org/W1988361083', 'https://openalex.org/W1991177744', 'https://openalex.org/W1992601827', 'https://openalex.org/W2002769350', 'https://openalex.org/W2006568580', 'https://openalex.org/W2009747613', 'https://openalex.org/W2009880851', 'https://openalex.org/W2012577197', 'https://openalex.org/W2019789856', 'https://openalex.org/W2027136734', 'https://openalex.org/W2029120648', 'https://openalex.org/W2041940817', 'https://openalex.org/W2041994770', 'https://openalex.org/W2042371906', 'https://openalex.org/W2047878721', 'https://openalex.org/W2054083814', 'https://openalex.org/W2054443936', 'https://openalex.org/W2056535053', 'https://openalex.org/W2058416613', 'https://openalex.org/W2063237605', 'https://openalex.org/W2066535642', 'https://openalex.org/W2067433745', 'https://openalex.org/W2069469763', 'https://openalex.org/W2069580248', 'https://openalex.org/W2082167334', 'https://openalex.org/W2087172186', 'https://openalex.org/W2088314252', 'https://openalex.org/W2088513824', 'https://openalex.org/W2091760428', 'https://openalex.org/W2097135161', 'https://openalex.org/W2097824035', 'https://openalex.org/W2099310552', 'https://openalex.org/W2100241249', 'https://openalex.org/W2118622904', 'https://openalex.org/W2119486893', 'https://openalex.org/W2128158693', 'https://openalex.org/W2130004811', 'https://openalex.org/W2131164826', 'https://openalex.org/W2132024007', 'https://openalex.org/W2134182567', 'https://openalex.org/W2137154133', 'https://openalex.org/W2137279955', 'https://openalex.org/W2141260882', 'https://openalex.org/W2145470537', 'https://openalex.org/W2150070295', 'https://openalex.org/W2167093722', 'https://openalex.org/W2169019804', 'https://openalex.org/W2170327822', 'https://openalex.org/W2170913623', 'https://openalex.org/W2413301451', 'https://openalex.org/W2531609094', 'https://openalex.org/W4246989676', 'https://openalex.org/W4247730450'], 'related_works': ['https://openalex.org/W4224261288', 'https://openalex.org/W3199701425', 'https://openalex.org/W3170212419', 'https://openalex.org/W3047551001', 'https://openalex.org/W2979548918', 'https://openalex.org/W2418917221', 'https://openalex.org/W2180401043', 'https://openalex.org/W2146252487', 'https://openalex.org/W2134182567', 'https://openalex.org/W2085703491'], 'abstract_inverted_index': {'Transient': [0, 142], 'receptor': [1, 143], 'potential': [2, 144], 'vanilloid': [3, 145], '4': [4, 146], '(TRPV4)': [5, 147], 'channel': [6, 19, 107, 148, 161, 249], 'is': [7, 149], 'a': [8, 36, 124, 150, 178, 266], 'physiological': [9, 151], 'sensor': [10, 152], 'for': [11, 127, 153, 269], 'hypo-osmolarity,': [12, 154], 'mechanical': [13, 155], 'deformation,': [14, 156], 'and': [15, 42, 51, 80, 91, 105, 132, 157, 184, 193, 222, 233, 247, 274], 'warm': [16, 158], 'temperature.': [17, 159], 'The': [18, 160], 'activation': [20, 162], 'leads': [21, 163], 'to': [22, 164], 'various': [23, 165], 'cellular': [24, 166], 'effects': [25, 167], 'involving': [26, 168], 'Ca2+': [27, 89, 169, 231], 'dynamics.': [28, 170], 'We': [29, 171], 'found': [30, 172], 'that': [31, 173], 'TRPV4': [32, 96, 128, 174, 238, 270], 'interacts': [33, 175], 'with': [34, 176], 'β-catenin,': [35, 177], 'crucial': [37, 179], 'component': [38, 180], 'linking': [39, 181], 'adherens': [40, 182], 'junctions': [41, 102, 136, 183, 244, 278], 'the': [43, 54, 65, 71, 100, 106, 130, 140, 185, 196, 207, 213, 242, 248, 272, 282], 'actin': [44, 78, 186, 220], 'cytoskeleton,': [45, 187], 'thereby': [46, 188], 'enhancing': [47, 189], 'cell-cell': [48, 101, 111, 135, 190, 243, 253, 277], 'junction': [49, 112, 191, 254], 'development': [50, 131, 192, 273], 'formation': [52, 194], 'of': [53, 64, 134, 139, 195, 206, 276, 281], 'tight': [55, 197], 'barrier': [56, 68, 198, 210], 'between': [57, 199], 'skin': [58, 200], 'keratinocytes.': [59, 201], 'TRPV4-deficient': [60, 74, 202, 216], 'mice': [61, 203], 'displayed': [62, 204], 'impairment': [63, 205], 'intercellular': [66, 117, 208, 259], 'junction-dependent': [67, 209], 'function': [69, 211], 'in': [70, 87, 115, 119, 129, 137, 212, 229, 257, 261, 271, 279], 'skin.': [72, 141, 214, 283], 'In': [73, 215], 'keratinocytes,': [75, 217], 'extracellular': [76, 218], 'Ca2+-induced': [77, 219], 'rearrangement': [79, 221], 'stratification': [81, 223], 'were': [82, 224], 'delayed': [83, 225], 'following': [84, 226], 'significant': [85, 227], 'reduction': [86, 228], 'cytosolic': [88, 230], 'increase': [90, 232], 'small': [92, 234], 'GTPase': [93, 235], 'Rho': [94, 236], 'activation.': [95, 237], 'protein': [97, 239], 'located': [98, 240], 'where': [99, 241], 'are': [103, 245], 'formed,': [104, 246], 'deficiency': [108, 250], 'caused': [109, 251], 'abnormal': [110, 252], 'structures,': [113, 255], 'resulting': [114, 256], 'higher': [116, 258], 'permeability': [118, 260], 'vitro.': [120, 262], 'Our': [121, 263], 'results': [122, 264], 'suggest': [123, 265], 'novel': [125, 267], 'role': [126, 268], 'maturation': [133, 275], 'epithelia': [138, 280]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1993229549', 'counts_by_year': [{'year': 2024, 'cited_by_count': 10}, {'year': 2023, 'cited_by_count': 13}, {'year': 2022, 'cited_by_count': 11}, {'year': 2021, 'cited_by_count': 12}, {'year': 2020, 'cited_by_count': 16}, {'year': 2019, 'cited_by_count': 15}, {'year': 2018, 'cited_by_count': 10}, {'year': 2017, 'cited_by_count': 13}, {'year': 2016, 'cited_by_count': 14}, {'year': 2015, 'cited_by_count': 17}, {'year': 2014, 'cited_by_count': 14}, {'year': 2013, 'cited_by_count': 6}, {'year': 2012, 'cited_by_count': 14}], 'updated_date': '2024-09-11T00:29:50.661388', 'created_date': '2016-06-24'}