Title: Automated visual choice discrimination learning in zebrafish (<i>Danio rerio</i>)
Abstract: Journal of Integrative NeuroscienceVol. 11, No. 01, pp. 73-85 (2012) ArticlesNo AccessAutomated visual choice discrimination learning in zebrafish (Danio rerio)Kaspar P. Mueller and Stephan C. F. NeuhaussKaspar P. MuellerInstitute of Molecular Life Sciences, University of Zurich, Winterthurerstrasse 190, Zürich, CH-8057, Switzerland and Stephan C. F. NeuhaussInstitute of Molecular Life Sciences, University of Zurich, Winterthurerstrasse 190, Zürich, CH-8057, SwitzerlandCorresponding author.https://doi.org/10.1142/S0219635212500057Cited by:32 PreviousNext AboutSectionsPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsRecommend to Library ShareShare onFacebookTwitterLinked InRedditEmail AbstractTraining experimental animals to discriminate between different visual stimuli has been an important tool in cognitive neuroscience as well as in vision research for many decades. Current methods used for visual choice discrimination training of zebrafish require human observers for response tracking, stimulus presentation and reward delivery and, consequently, are very labor intensive and possibly experimenter biased. By combining video tracking of fish positions, stimulus presentation on computer monitors and food delivery by computer-controlled electromagnetic valves, we developed a method that allows for a fully automated training of multiple adult zebrafish to arbitrary visual stimuli in parallel. The standardized training procedure facilitates the comparison of results across different experiments and laboratories and contributes to the usability of zebrafish as vertebrate model organisms in behavioral brain research and vision research.Keywords:Zebrafishvisual behaviorlearningmemoryautomated behavioral testing References L. Al-Imari and R. Gerlai, Behav. Brain. Res. 189, 216 (2008), DOI: 10.1016/j.bbr.2007.12.007. Crossref, Medline, ISI, Google ScholarD. 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