Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1993074106', 'doi': 'https://doi.org/10.1016/j.bmc.2012.04.056', 'title': '5-(5-(6-[11C]methyl-3,6-diazabicyclo[3.2.0]heptan-3-yl)pyridin-2-yl)-1H-indole as a potential PET radioligand for imaging cerebral α7-nAChR in mice', 'display_name': '5-(5-(6-[11C]methyl-3,6-diazabicyclo[3.2.0]heptan-3-yl)pyridin-2-yl)-1H-indole as a potential PET radioligand for imaging cerebral α7-nAChR in mice', 'publication_year': 2012, 'publication_date': '2012-05-05', 'ids': {'openalex': 'https://openalex.org/W1993074106', 'doi': 'https://doi.org/10.1016/j.bmc.2012.04.056', 'mag': '1993074106', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/22608919', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3527104'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.bmc.2012.04.056', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S10422866', 'display_name': 'Bioorganic & Medicinal Chemistry', 'issn_l': '0968-0896', 'issn': ['0968-0896', '1464-3391'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://europepmc.org/articles/pmc3527104?pdf=render', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5101788579', 'display_name': 'Gao Y', 'orcid': 'https://orcid.org/0000-0003-2059-3168'}, 'institutions': [{'id': 'https://openalex.org/I2799853436', 'display_name': 'Johns Hopkins Medicine', 'ror': 'https://ror.org/037zgn354', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799853436']}, {'id': 'https://openalex.org/I145311948', 'display_name': 'Johns Hopkins University', 'ror': 'https://ror.org/00za53h95', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I145311948']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Yongjun Gao', 'raw_affiliation_strings': ['Division of Nuclear Medicine, Department of Radiology, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287-0816, USA'], 'affiliations': [{'raw_affiliation_string': 'Division of Nuclear Medicine, Department of Radiology, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287-0816, USA', 'institution_ids': ['https://openalex.org/I2799853436', 'https://openalex.org/I145311948']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5005602721', 'display_name': 'Hayden T. Ravert', 'orcid': 'https://orcid.org/0000-0002-5076-8961'}, 'institutions': [{'id': 'https://openalex.org/I145311948', 'display_name': 'Johns Hopkins University', 'ror': 'https://ror.org/00za53h95', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I145311948']}, {'id': 'https://openalex.org/I2799853436', 'display_name': 'Johns Hopkins Medicine', 'ror': 'https://ror.org/037zgn354', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799853436']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Hayden T. Ravert', 'raw_affiliation_strings': ['Division of Nuclear Medicine, Department of Radiology, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287-0816, USA'], 'affiliations': [{'raw_affiliation_string': 'Division of Nuclear Medicine, Department of Radiology, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287-0816, USA', 'institution_ids': ['https://openalex.org/I145311948', 'https://openalex.org/I2799853436']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5006400873', 'display_name': 'Heather Valentine', 'orcid': 'https://orcid.org/0000-0001-6675-5578'}, 'institutions': [{'id': 'https://openalex.org/I2799853436', 'display_name': 'Johns Hopkins Medicine', 'ror': 'https://ror.org/037zgn354', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799853436']}, {'id': 'https://openalex.org/I145311948', 'display_name': 'Johns Hopkins University', 'ror': 'https://ror.org/00za53h95', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I145311948']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Heather Valentine', 'raw_affiliation_strings': ['Division of Nuclear Medicine, Department of Radiology, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287-0816, USA'], 'affiliations': [{'raw_affiliation_string': 'Division of Nuclear Medicine, Department of Radiology, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287-0816, USA', 'institution_ids': ['https://openalex.org/I2799853436', 'https://openalex.org/I145311948']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5072542113', 'display_name': 'Ursula Scheffel', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2799853436', 'display_name': 'Johns Hopkins Medicine', 'ror': 'https://ror.org/037zgn354', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799853436']}, {'id': 'https://openalex.org/I145311948', 'display_name': 'Johns Hopkins University', 'ror': 'https://ror.org/00za53h95', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I145311948']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ursula Scheffel', 'raw_affiliation_strings': ['Division of Nuclear Medicine, Department of Radiology, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287-0816, USA'], 'affiliations': [{'raw_affiliation_string': 'Division of Nuclear Medicine, Department of Radiology, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287-0816, USA', 'institution_ids': ['https://openalex.org/I2799853436', 'https://openalex.org/I145311948']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5061804526', 'display_name': 'Paige Finley', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2799853436', 'display_name': 'Johns Hopkins Medicine', 'ror': 'https://ror.org/037zgn354', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799853436']}, {'id': 'https://openalex.org/I145311948', 'display_name': 'Johns Hopkins University', 'ror': 'https://ror.org/00za53h95', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I145311948']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Paige Finley', 'raw_affiliation_strings': ['Division of Nuclear Medicine, Department of Radiology, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287-0816, USA'], 'affiliations': [{'raw_affiliation_string': 'Division of Nuclear Medicine, Department of Radiology, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287-0816, USA', 'institution_ids': ['https://openalex.org/I2799853436', 'https://openalex.org/I145311948']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5000122559', 'display_name': 'Dean F. Wong', 'orcid': 'https://orcid.org/0000-0001-9343-8367'}, 'institutions': [{'id': 'https://openalex.org/I2799853436', 'display_name': 'Johns Hopkins Medicine', 'ror': 'https://ror.org/037zgn354', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799853436']}, {'id': 'https://openalex.org/I145311948', 'display_name': 'Johns Hopkins University', 'ror': 'https://ror.org/00za53h95', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I145311948']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Dean F. Wong', 'raw_affiliation_strings': ['Division of Nuclear Medicine, Department of Radiology, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287-0816, USA'], 'affiliations': [{'raw_affiliation_string': 'Division of Nuclear Medicine, Department of Radiology, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287-0816, USA', 'institution_ids': ['https://openalex.org/I2799853436', 'https://openalex.org/I145311948']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5021803422', 'display_name': 'Robert F. Dannals', 'orcid': 'https://orcid.org/0000-0002-5483-5914'}, 'institutions': [{'id': 'https://openalex.org/I2799853436', 'display_name': 'Johns Hopkins Medicine', 'ror': 'https://ror.org/037zgn354', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799853436']}, {'id': 'https://openalex.org/I145311948', 'display_name': 'Johns Hopkins University', 'ror': 'https://ror.org/00za53h95', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I145311948']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Robert F. Dannals', 'raw_affiliation_strings': ['Division of Nuclear Medicine, Department of Radiology, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287-0816, USA'], 'affiliations': [{'raw_affiliation_string': 'Division of Nuclear Medicine, Department of Radiology, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287-0816, USA', 'institution_ids': ['https://openalex.org/I2799853436', 'https://openalex.org/I145311948']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5090150971', 'display_name': 'Andrew G. Horti', 'orcid': 'https://orcid.org/0000-0003-2290-488X'}, 'institutions': [{'id': 'https://openalex.org/I2799853436', 'display_name': 'Johns Hopkins Medicine', 'ror': 'https://ror.org/037zgn354', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2799853436']}, {'id': 'https://openalex.org/I145311948', 'display_name': 'Johns Hopkins University', 'ror': 'https://ror.org/00za53h95', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I145311948']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Andrew G. Horti', 'raw_affiliation_strings': ['Division of Nuclear Medicine, Department of Radiology, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287-0816, USA'], 'affiliations': [{'raw_affiliation_string': 'Division of Nuclear Medicine, Department of Radiology, The Johns Hopkins University School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287-0816, USA', 'institution_ids': ['https://openalex.org/I2799853436', 'https://openalex.org/I145311948']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3690, 'currency': 'USD', 'value_usd': 3690, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.812, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 8, 'citation_normalized_percentile': {'value': 0.588524, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 83, 'max': 84}, 'biblio': {'volume': '20', 'issue': '12', 'first_page': '3698', 'last_page': '3702'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11818', 'display_name': 'Structure and Function of Nicotinic Receptors', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11818', 'display_name': 'Structure and Function of Nicotinic Receptors', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11178', 'display_name': 'Structure and Function of G Protein-Coupled Receptors', 'score': 0.9975, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13047', 'display_name': 'Role of Sigma Receptors in Cellular Signaling', 'score': 0.9951, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/radiosynthesis', 'display_name': 'Radiosynthesis', 'score': 0.971334}, {'id': 'https://openalex.org/keywords/radioligand', 'display_name': 'Radioligand', 'score': 0.86709964}, {'id': 'https://openalex.org/keywords/desmethyl', 'display_name': 'Desmethyl', 'score': 0.78525054}, {'id': 'https://openalex.org/keywords/biodistribution', 'display_name': 'Biodistribution', 'score': 0.7163064}, {'id': 'https://openalex.org/keywords/nicotinic-acetylcholine-receptors', 'display_name': 'Nicotinic Acetylcholine Receptors', 'score': 0.515973}], 'concepts': [{'id': 'https://openalex.org/C2776970183', 'wikidata': 'https://www.wikidata.org/wiki/Q20155580', 'display_name': 'Radiosynthesis', 'level': 3, 'score': 0.971334}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.95141625}, {'id': 'https://openalex.org/C67847695', 'wikidata': 'https://www.wikidata.org/wiki/Q626478', 'display_name': 'Radioligand', 'level': 3, 'score': 0.86709964}, {'id': 'https://openalex.org/C2780837634', 'wikidata': 'https://www.wikidata.org/wiki/Q1996532', 'display_name': 'Desmethyl', 'level': 3, 'score': 0.78525054}, {'id': 'https://openalex.org/C2777807558', 'wikidata': 'https://www.wikidata.org/wiki/Q4914764', 'display_name': 'Biodistribution', 'level': 3, 'score': 0.7163064}, {'id': 'https://openalex.org/C192527728', 'wikidata': 'https://www.wikidata.org/wiki/Q1465700', 'display_name': 'Indole test', 'level': 2, 'score': 0.5759171}, {'id': 'https://openalex.org/C207001950', 'wikidata': 'https://www.wikidata.org/wiki/Q141124', 'display_name': 'In vivo', 'level': 2, 'score': 0.5686126}, {'id': 'https://openalex.org/C188987157', 'wikidata': 'https://www.wikidata.org/wiki/Q7030581', 'display_name': 'Nicotinic agonist', 'level': 3, 'score': 0.49766663}, {'id': 'https://openalex.org/C177322064', 'wikidata': 'https://www.wikidata.org/wiki/Q750955', 'display_name': 'Radiochemistry', 'level': 1, 'score': 0.4789665}, {'id': 'https://openalex.org/C114373084', 'wikidata': 'https://www.wikidata.org/wiki/Q273499', 'display_name': 'Chemical synthesis', 'level': 3, 'score': 0.44864377}, {'id': 'https://openalex.org/C24961977', 'wikidata': 'https://www.wikidata.org/wiki/Q225972', 'display_name': 'Bicyclic molecule', 'level': 2, 'score': 0.42612568}, {'id': 'https://openalex.org/C71240020', 'wikidata': 'https://www.wikidata.org/wiki/Q186011', 'display_name': 'Stereochemistry', 'level': 1, 'score': 0.35817438}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.27975237}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.22727081}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.16637188}, {'id': 'https://openalex.org/C2777477808', 'wikidata': 'https://www.wikidata.org/wiki/Q407595', 'display_name': 'Metabolite', 'level': 2, 'score': 0.14313579}, {'id': 'https://openalex.org/C150903083', 'wikidata': 'https://www.wikidata.org/wiki/Q7108', 'display_name': 'Biotechnology', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001921', 'descriptor_name': 'Brain', 'qualifier_ui': 'Q000000981', 'qualifier_name': 'diagnostic imaging', 'is_major_topic': True}, {'descriptor_ui': 'D007211', 'descriptor_name': 'Indoles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D049268', 'descriptor_name': 'Positron-Emission Tomography', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D011725', 'descriptor_name': 'Pyridines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D019275', 'descriptor_name': 'Radiopharmaceuticals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D011978', 'descriptor_name': 'Receptors, Nicotinic', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001921', 'descriptor_name': 'Brain', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001921', 'descriptor_name': 'Brain', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D019086', 'descriptor_name': 'Bridged Bicyclo Compounds, Heterocyclic', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D019086', 'descriptor_name': 'Bridged Bicyclo Compounds, Heterocyclic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007211', 'descriptor_name': 'Indoles', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': False}, {'descriptor_ui': 'D008024', 'descriptor_name': 'Ligands', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008815', 'descriptor_name': 'Mice, Inbred Strains', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015394', 'descriptor_name': 'Molecular Structure', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011725', 'descriptor_name': 'Pyridines', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': False}, {'descriptor_ui': 'D011812', 'descriptor_name': 'Quinuclidines', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D011812', 'descriptor_name': 'Quinuclidines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019275', 'descriptor_name': 'Radiopharmaceuticals', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': False}, {'descriptor_ui': 'D019275', 'descriptor_name': 'Radiopharmaceuticals', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D011978', 'descriptor_name': 'Receptors, Nicotinic', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011978', 'descriptor_name': 'Receptors, Nicotinic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D064569', 'descriptor_name': 'alpha7 Nicotinic Acetylcholine Receptor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.bmc.2012.04.056', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S10422866', 'display_name': 'Bioorganic & Medicinal Chemistry', 'issn_l': '0968-0896', 'issn': ['0968-0896', '1464-3391'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3527104', 'pdf_url': 'https://europepmc.org/articles/pmc3527104?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527104', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/22608919', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3527104', 'pdf_url': 'https://europepmc.org/articles/pmc3527104?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 21, 'referenced_works': ['https://openalex.org/W1542679752', 'https://openalex.org/W1985093720', 'https://openalex.org/W1993337719', 'https://openalex.org/W2000913567', 'https://openalex.org/W2006928837', 'https://openalex.org/W2016729909', 'https://openalex.org/W2021616621', 'https://openalex.org/W2033154101', 'https://openalex.org/W2036216077', 'https://openalex.org/W2056917644', 'https://openalex.org/W2057552760', 'https://openalex.org/W2058339296', 'https://openalex.org/W2059723162', 'https://openalex.org/W2060469597', 'https://openalex.org/W2062579873', 'https://openalex.org/W2064193836', 'https://openalex.org/W2073208182', 'https://openalex.org/W2090060532', 'https://openalex.org/W2096264830', 'https://openalex.org/W2106431483', 'https://openalex.org/W2143680784'], 'related_works': ['https://openalex.org/W4321366306', 'https://openalex.org/W3116503129', 'https://openalex.org/W2608354820', 'https://openalex.org/W2597774651', 'https://openalex.org/W2516610867', 'https://openalex.org/W2312169439', 'https://openalex.org/W2083209604', 'https://openalex.org/W2044963831', 'https://openalex.org/W2026326619', 'https://openalex.org/W1971543955'], 'abstract_inverted_index': {'The': [0, 74], 'radiosynthesis': [1], 'and': [2, 27, 61, 94], 'in': [3, 34, 45, 85], 'vivo': [4], 'evaluation': [5], 'of': [6, 22, 39, 50, 66], '5-(5-(6-[11C]methyl-3,6-diazabicyclo[3.2.0]heptan-3-yl)pyridin-2-yl)-1H-indole': [7], '[11C]rac-(1),': [8], 'a': [9], 'potential': [10], 'PET': [11], 'tracer': [12], 'for': [13], 'α7': [14], 'nicotinic': [15], 'acetylcholine': [16], 'receptors': [17], '(α7-nAChR),': [18], 'are': [19], 'described.': [20], 'Syntheses': [21], 'the': [23, 91], 'nonradioactive': [24], 'standard': [25], 'rac-1': [26], 'corresponding': [28], 'desmethyl': [29], 'precursor': [30], '7': [31, 40], 'were': [32], 'achieved': [33], 'several': [35], 'reaction': [36], 'steps.': [37], 'Radiomethylation': [38], 'with': [41, 57], '[11C]CH3I': [42], 'afforded': [43], '[11C]rac-1': [44, 89], 'an': [46, 62], 'average': [47, 63], 'radiochemical': [48, 59], 'yield': [49], '30': [51, 79], '±': [52, 68], '5%': [53], '(n': [54, 71], '=': [55, 72], '5)': [56], 'high': [58], 'purity': [60], 'specific': [64], 'radioactivity': [65], '444': [67], '74': [69], 'GBq/μmol': [70], '5).': [73], 'total': [75], 'synthesis': [76], 'time': [77], 'was': [78], 'min': [80], 'from': [81], 'end-of-bombardment.': [82], 'Biodistribution': [83], 'studies': [84], 'mice': [86], 'showed': [87], 'that': [88], 'penetrates': [90], 'blood–brain': [92], 'barrier': [93], 'specifically': [95], 'labels': [96], 'neuronal': [97], 'α7-nAChRs.': [98]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1993074106', 'counts_by_year': [{'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 2}], 'updated_date': '2024-09-17T15:08:09.342982', 'created_date': '2016-06-24'}