Publication Information

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'mesh': [{'descriptor_ui': 'D009687', 'descriptor_name': 'Nuclear Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D011987', 'descriptor_name': 'Receptors, Steroid', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D015534', 'descriptor_name': 'Trans-Activators', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D014157', 'descriptor_name': 'Transcription Factors', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D015533', 'descriptor_name': 'Transcriptional Activation', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050882', 'descriptor_name': 'CREB-Binding Protein', 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1776, 3919], '3': [14, 198, 1777, 4140, 4181], '(RAC3)': [15, 199], 'was': [16, 200, 769, 2687, 2837, 3163, 3303, 3354, 3710], 'recently': [17, 201], 'identified': [18, 46, 202, 230, 703, 846, 1021], 'to': [19, 23, 61, 168, 203, 207, 245, 352, 781, 1139, 1285, 1296, 1375, 1479, 1492, 1981, 2105, 2577, 2663, 2821, 3035, 3181, 3204, 3689, 3765, 4090, 4101, 4111, 4120, 4135, 4220, 4333, 4352], 'be': [20, 204, 1469, 3844, 4334], 'highly': [21, 205, 1986], 'related': [22, 206, 1002, 4095], 'the': [24, 79, 82, 98, 108, 117, 128, 181, 208, 263, 266, 282, 292, 301, 312, 365, 572, 642, 670, 692, 775, 1006, 1015, 1033, 1143, 1148, 1287, 1294, 1301, 1324, 1348, 1376, 1472, 1501, 1558, 1575, 1699, 1774, 1881, 1968, 1974, 1982, 2092, 2164, 2175, 2203, 2206, 2211, 2237, 2264, 2284, 2320, 2347, 2352, 2567, 2691, 2729, 2733, 2743, 2755, 2871, 2946, 2949, 3036, 3041, 3066, 3258, 3263, 3266, 3288, 3298, 3307, 3332, 3340, 3348, 3361, 3478, 3539, 3548, 3580, 3593, 3597, 3639, 3653, 3678, 3682, 3695, 3746, 3753, 3766, 3771, 3792, 3801, 3821, 3852, 3866, 3869, 3879, 3916, 3961, 3986, 4075, 4122, 4143, 4169, 4176, 4186, 4210, 4270, 4283, 4302, 4317, 4329, 4341, 4358, 4362, 4368, 4374, 4378, 4382, 4391, 4396, 4402, 4408, 4422, 4428], 'steroid': [25, 141, 209, 325, 391, 1576], 'receptor': [26, 40, 64, 80, 142, 210, 224, 248, 264, 326, 392, 610, 767, 777, 1017, 1350, 1378, 1481, 1570, 1577, 2015, 2177, 2197, 2286, 2301, 3259, 3333, 3515, 3545, 3703, 3837], 'coactivator-1': [27, 143, 211, 327, 1578], 'and': [28, 68, 96, 101, 127, 140, 149, 152, 178, 212, 252, 280, 285, 311, 324, 333, 336, 362, 436, 447, 590, 602, 632, 675, 690, 695, 811, 970, 1011, 1014, 1024, 1135, 1147, 1152, 1247, 1347, 1463, 1483, 1499, 1563, 1773, 1783, 1886, 1893, 1904, 2002, 2017, 2179, 2185, 2229, 2241, 2276, 2522, 2542, 2608, 2630, 2732, 2813, 2851, 2866, 2882, 2884, 2943, 2948, 2963, 3018, 3093, 3104, 3119, 3137, 3194, 3201, 3225, 3261, 3268, 3317, 3326, 3351, 3432, 3482, 3490, 3513, 3531, 3543, 3650, 3657, 3779, 3797, 3818, 3860, 3875, 3921, 3972, 3990, 4004, 4106, 4147, 4156, 4173, 4197, 4216, 4239, 4250, 4255, 4261, 4275, 4287, 4308, 4320, 4328, 4387, 4407, 4427], 'transcriptional': [29, 94, 109, 136, 170, 213, 278, 293, 320, 354, 693, 1030, 1144, 1243, 1461, 1566, 1700, 2018, 2180, 2200, 2249, 2281, 3706, 3848, 3907, 3918], 'intermediate': [30, 137, 214, 321, 1701], 'factor': [31, 138, 215, 322, 1326, 1702], '2,': [32, 139, 216, 323], 'thereby': [33, 217], 'establishing': [34, 218], 'a': [35, 47, 87, 120, 219, 231, 271, 304, 561, 577, 591, 682, 1990, 2008, 2234, 2274, 2548, 2634, 2831, 2999, 3060, 3096, 3218, 3487, 3526, 3664, 3670, 3787, 3811, 3886, 4125, 4130, 4223, 4337], 'novel': [36, 220], 'family': [37, 221, 1353, 1573, 1913, 1976], 'of': [38, 78, 91, 119, 175, 222, 262, 275, 303, 359, 442, 585, 600, 637, 644, 672, 685, 698, 763, 774, 1382, 1476, 1505, 1560, 1863, 1873, 1911, 1970, 2021, 2097, 2166, 2183, 2205, 2213, 2248, 2256, 2280, 2305, 2319, 2574, 2833, 2874, 3008, 3021, 3051, 3062, 3076, 3151, 3211, 3253, 3265, 3416, 3550, 3596, 3638, 3681, 3708, 3748, 3756, 3855, 3857, 4087, 4099, 4116, 4124, 4178, 4188, 4212, 4244, 4259, 4347, 4354, 4365, 4377, 4414], 'coactivators.': [41, 225, 2168, 2287], 'In': [42, 130, 226, 314, 999, 1373, 1979, 2169, 2259, 2619, 3065, 3662, 3774, 4367], 'this': [43, 56, 227, 240, 1912, 1971, 2170, 3412, 3521, 3757, 4137], 'study,': [44, 228, 2171], 'we': [45, 132, 229, 316, 2172, 2261, 3249, 3485, 3576, 3823, 3839, 3948, 4372], 'RAC3': [48, 92, 165, 232, 276, 349, 2184, 2220, 2231, 2265, 2294, 2310, 2322, 3212, 3417, 3530, 3542, 3656, 3698, 3709, 3749, 3951, 3982, 4100, 4155, 4166, 4231, 4245, 4263, 4379], 'fragment': [49, 90, 233, 274, 3220, 3342, 3364, 3759], 'containing': [50, 123, 234, 307, 1989, 2870], 'three': [51, 103, 235, 287, 2023, 2671, 3419, 3495, 3643, 3870], 'LXXLL': [52, 105, 236, 289, 1991, 2189, 2215, 2336, 3420, 3827, 3902], 'motifs': [53, 106, 237, 290, 1988, 2087, 2099, 2157, 2190, 3831, 3859, 3872, 3903], 'conserved': [54, 238, 1987, 2003, 2156, 3826], 'among': [55, 239], 'family,': [57, 241], 'which': [58, 242, 3312, 3422], 'is': [59, 155, 243, 339, 1283, 2254, 2267, 2388, 3130, 3366, 3584, 3699, 3750, 4078, 4089, 4118, 4264, 4296, 4349], 'sufficient': [60, 244, 4079, 4219], 'mediate': [62, 246, 605, 2106, 3906, 4121], 'interaction': [65, 249, 2016, 2109, 2178, 2198, 2238, 3260, 3302, 3353, 3362, 3429, 3493, 3528, 3540, 3631, 3654, 4170, 4236], 'vivo': [67, 251], 'vitro.': [70, 254], 'Point': [71, 255], 'mutations': [72, 256, 3591, 3647], 'that': [73, 86, 102, 134, 153, 164, 257, 270, 286, 318, 337, 348, 570, 687, 1027, 1242, 1867, 2011, 2154, 2187, 2219, 2230, 2245, 2263, 2293, 3251, 3262, 3293, 3339, 3520, 3538, 3636, 3677, 3697, 3745, 3841, 3862, 3899, 3981, 4074, 4084, 4165, 4209, 4230, 4353], 'disrupt': [74, 258], 'ligand-dependent': [75, 259, 398, 3527, 3672], 'function': [77, 261, 575, 1899, 2212, 3641, 3680, 3854, 4086], 'inhibited': [81, 265], 'interaction.': [83, 267, 3588, 3673], 'We': [84, 268, 2217, 3337, 3534, 3634, 3850, 3979, 4071, 4128], 'found': [85, 269, 780, 1138, 2006, 2186, 2262, 3338, 3635, 3769, 3824, 3861, 4373, 4416], '162-amino': [88, 272], 'acid': [89, 273, 3314], 'conferred': [93, 277], 'recruited': [97, 281], 'CREB-binding': [99, 124, 283, 308, 409], 'protein': [100, 284, 2537], 'distinct': [104, 288, 4233], 'mediated': [107, 291], 'activation.': [110, 294, 3849], 'A': [111, 295], 'trimeric': [112, 296, 4131], 'far': [113, 297, 3501, 4132], 'Western': [114, 298, 3502, 4133], 'analysis': [115, 299], 'demonstrated': [116, 300, 3536], 'formation': [118, 302, 4123], 'ternary': [121, 305, 4126, 4224], 'complex': [122, 306, 1289], 'protein,': [125, 309], 'RAC3,': [126, 135, 310, 319, 386, 3692, 3970, 4355], 'receptor.': [129, 313, 4161], 'addition,': [131, 315, 2260], 'showed': [133, 317, 2218], 'expressed': [145, 329, 3039, 4265, 4297, 4335], 'specific': [147, 331, 586, 3116], 'tissues': [148, 332, 4249], 'cancer': [150, 334, 3195, 4251, 4370], 'cells': [151, 335, 2526, 2788, 2823, 2861, 2879, 2914, 3069, 3743, 3892, 4252, 4386], 'RAC3transcript': [154, 338], 'directly': [156, 340, 2222, 2268, 3845, 3905], 'up-regulated': [157, 341, 2269], 'retinoid': [159, 343, 412, 608], 'treatment.': [160, 344], 'These': [161, 345, 2086, 3674, 3808, 3896, 4206, 4226], 'results': [162, 346, 2290, 3675, 3809, 3897, 4163, 4207, 4227], 'suggest': [163, 347, 1488, 2292, 3676, 4208], 'may': [166, 350, 1496, 3904], 'contribute': [167, 351], 'amplified': [169, 353], 'responses': [171, 355], 'through': [172, 356, 2225, 2303], 'both': [173, 357, 2013, 3319, 4104], 'recruitment': [174, 358, 2255], 'additional': [176, 360, 2257], 'autoregulation': [179, 363], 'receptor-coactivator': [182, 366], 'complex.': [183, 367, 4127, 4225], 'regulation': [369], 'receptors': [372, 557, 700, 1035, 1295, 1467, 2112, 3283, 3434, 3497, 4108], 'for': [373, 583, 1009, 2236, 2945, 2960, 2967, 3059, 3117, 3187, 3586, 3627, 3835, 3966, 4080, 4235], 'steroids,': [374], 'thyroid': [375, 383], 'hormones': [376], '(TR),': [377], '1The': [378], 'abbreviations': [379], 'used': [380], 'are:': [381], 'TR,': [382, 3512], 'receptor;': [385, 413], '3;': [389], 'SRC,': [390], 'coactivator;': [393], 'AF,': [394], 'function;': [396], 'AF-2,': [397], 'AF;': [399], 'AF2-AD,': [400], 'AF-2': [401, 3581, 3640], 'domain;': [403, 407, 419, 422], 'DBD,': [404, 3868], 'DNA': [405, 578, 587, 1502, 3114], 'binding': [406, 579, 594, 598, 1282, 1503], 'CBP,': [408], 'protein;': [410], 'RAR,': [411, 3322, 3511], 'HAT,': [414], 'histone': [415, 1149, 1251, 1388], 'acetyltransferase;': [416], 'LCD,': [417], 'leucine-charged': [418, 2093], 'RID,': [420], 'receptor-interacting': [421, 3209, 3413, 3767], 'Gal,': [423], 'galactosidase;': [424], 'poly-Q,': [425], 'polyglutamine;': [426], 'bHLH,': [427], 'basic': [428, 1883], 'helix-loop-helix;': [429], 'PAS,': [430], 'period-aryl': [431, 1887], 'hydrocarbon': [432, 1888], 'receptor-single-minded.': [433], 'retinoids': [434], '(RAR),': [435], 'vitamin': [437], 'D3': [438], 'controls': [439], 'key': [440], 'aspects': [441], 'animal': [443], 'development,': [444], 'reproduction,': [445], 'homeostasis,': [446], 'adult': [448], 'organ': [449], 'physiology': [450], '(for': [451, 612, 704, 1305, 1355], 'reviews,': [452, 705], 'see': [453, 614, 706, 1307, 1357], 'Refs.': [454], '1Mangelsdorf': [455], 'D.J.': [456, 490, 617, 821, 1228], 'Thummel': [457], 'C.': [458, 857, 1226, 1685, 1687, 1714, 2435], 'Beato': [459, 929], 'M.': [460, 472, 508, 524, 788, 794, 859, 895, 901, 916, 930, 1080, 1161], 'Herrlich': [461, 525], 'P.': [462, 470, 474, 506, 510, 526, 798, 1716, 1955, 2437], 'Schütz': [463, 527], 'G.': [464, 528, 853, 1169, 1432, 1660, 3926, 4049], 'Umesono': [465, 818, 2764, 2894, 2924, 2974], 'K.': [466, 819, 1732, 1757, 2360, 2472, 2698, 2765, 2895, 2925, 2975], 'Blumberg': [467], 'B.': [468, 792, 1072, 1632, 4021], 'Kastner': [469], 'Mark': [471, 507], 'Chambon': [473, 509, 797, 1715, 2436], 'Evans': [475, 491, 618, 826, 988, 1052, 1207, 1845, 2400, 2477, 2499, 2766, 2896, 2926, 2976, 3608], 'R.M.': [476, 492, 619, 827, 989, 1053, 1157, 1208, 1846, 2401, 2478, 2500, 2767, 2897, 2927, 2977, 3609], 'Cell.': [477, 493, 511, 529, 543, 620, 737, 799, 828, 1123, 1209, 1267, 1415, 1516, 1643, 1763, 1847, 2479, 4032], '1995;': [478, 494, 512, 530, 544, 621, 907, 936, 980, 991, 1044, 1055, 1086, 1592, 1923, 1944, 2403, 2508, 3617], '83:': [479, 495, 513, 531, 545, 622], '835-839Abstract': [480], 'Full': [481, 497, 515, 533, 547, 624, 803, 832, 939, 941, 1213, 1215, 1271, 1273, 1419, 1421, 1520, 1522, 1547, 1549, 1647, 1649, 1851, 1853, 1926, 1928, 2483, 4036, 4038], 'Text': [482, 498, 516, 534, 548, 625, 804, 833, 940, 942, 1214, 1216, 1272, 1274, 1420, 1422, 1521, 1523, 1548, 1550, 1648, 1650, 1852, 1854, 1927, 1929, 2484, 4037, 4039], 'PDF': [483, 499, 517, 535, 549, 626, 805, 834, 943, 1217, 1275, 1423, 1524, 1551, 1651, 1855, 1930, 2485, 4040], 'PubMed': [484, 500, 518, 536, 550, 627, 664, 724, 742, 806, 835, 864, 887, 910, 944, 965, 983, 994, 1047, 1058, 1089, 1103, 1128, 1188, 1218, 1236, 1259, 1276, 1317, 1342, 1400, 1424, 1455, 1525, 1552, 1595, 1616, 1652, 1677, 1724, 1749, 1768, 1801, 1824, 1856, 1931, 1947, 2042, 2065, 2081, 2131, 2148, 2378, 2406, 2425, 2445, 2466, 2486, 2511, 2716, 2778, 2908, 2938, 2988, 3243, 3390, 3407, 3453, 3470, 3570, 3620, 3733, 3943, 4041, 4066], 'Scopus': [485, 501, 519, 537, 551, 628, 665, 725, 743, 807, 836, 865, 888, 911, 945, 966, 995, 1059, 1090, 1104, 1129, 1189, 1219, 1237, 1260, 1277, 1318, 1343, 1401, 1425, 1456, 1526, 1553, 1596, 1617, 1653, 1678, 1725, 1750, 1769, 1802, 1825, 1857, 1932, 1948, 1963, 2043, 2066, 2082, 2132, 2149, 2379, 2407, 2426, 2446, 2467, 2487, 2512, 2717, 2779, 2909, 2939, 2989, 3244, 3391, 3408, 3454, 3471, 3571, 3621, 3734, 3944, 4042, 4067], '(6088)': [486], 'Google': [487, 503, 521, 539, 553, 630, 667, 727, 745, 759, 809, 838, 867, 890, 913, 947, 968, 984, 997, 1048, 1061, 1092, 1106, 1131, 1191, 1221, 1239, 1262, 1279, 1320, 1345, 1371, 1403, 1427, 1458, 1528, 1555, 1598, 1619, 1655, 1680, 1697, 1727, 1752, 1771, 1804, 1827, 1859, 1934, 1950, 1965, 2045, 2068, 2084, 2134, 2151, 2381, 2409, 2428, 2448, 2469, 2489, 2514, 2719, 2781, 2911, 2941, 2991, 3246, 3393, 3410, 3456, 3473, 3573, 3623, 3736, 3946, 4044, 4069], 'Scholar,': [488, 504, 522, 540, 728, 746, 868, 891, 914, 948, 985, 1049, 1062, 1093, 1107, 1192, 1222, 1404, 1428, 1529, 1599, 1620, 1656, 1681, 1728, 1753, 1805, 1828, 1935, 1951, 2046, 2135, 2410, 2429, 2449, 2470, 2490, 3394, 3457, 4045], '2Mangelsdorf': [489, 616], '841-850Abstract': [496, 623], '(2837)': [502, 629], '3Kastner': [505], '859-869Abstract': [514], '(939)': [520], '4Beato': [523], '851-857Abstract': [532], '(1638)': [538], '5Thummel': [541], 'C.S.': [542], '871-877Abstract': [546], '(308)': [552], 'Scholar).': [554, 668, 760, 839, 998, 1132, 1280, 1372, 1459, 1860, 2085, 2382, 2720, 2782, 2912, 2992, 3247, 3474, 3574, 3737, 4070], 'characterized': [559, 2174], 'common': [562, 1478], 'domain': [563, 580, 1898, 1972, 2228, 2736, 3210, 3414, 3523, 3768, 3963], 'structure,': [564], 'including': [565], 'an': [566, 1870, 2160, 2296, 3073, 3088, 3551, 3700], 'N-terminal': [567, 1882, 3267, 3880], 'A/B': [568], 'region': [569, 2010], 'contains': [571, 1574, 3418], 'first': [573, 770, 4151], '(AF-1),': [576], '(DBD)': [581], 'responsible': [582], 'recognition': [584], 'response': [588], 'elements,': [589], 'C-terminal': [592, 3269, 3793, 3871, 3901], 'ligand': [593, 597, 651, 4179, 4189], 'domain.': [595, 3300], 'domains': [599, 2094, 2182, 4234], 'TR': [601, 1012], 'RAR': [603, 1010, 3275, 4174], 'also': [604, 1487, 1497, 1580, 1705, 1779, 2089, 3344, 3953, 4072, 4228], 'heterodimerization': [606], 'with': [607, 689, 783, 812, 1142, 1877, 2110, 2223, 2328, 2602, 2673, 2754, 2802, 2864, 2998, 3048, 3072, 3100, 3112, 3273, 3321, 3331, 3347, 3363, 3369, 3494, 3509, 3632, 3686, 3691, 3865, 3915, 3955, 3985, 3994, 4000, 4007, 4103, 4152, 4158, 4202, 4237, 4257, 4357], 'X': [609], '(RXR)': [611], 'review,': [613, 1306, 1356], 'Ref.': [615, 1308, 1358], 'Scholar),': [631, 1240, 1346, 1556, 1698, 1772, 1966, 2152, 3411, 3947], 'such': [633, 673, 842, 1299, 3352, 3587], 'complexes': [634, 1141], 'capable': [636], 'repressing': [638], 'basal': [639], 'transcription': [640, 649, 814, 1510, 3785, 3884], 'absence': [643, 4187], 'ligand,': [645, 3359], 'while': [646], 'activating': [647], 'net': [648], 'upon': [650], 'treatment': [652], '(6Baniahmad': [653], 'A.': [654, 883, 897, 961, 1076, 1115, 1531, 1601, 1673, 1734, 1745, 1797, 1838, 2038, 2462, 2498, 2507, 2774, 2904, 2934, 2984, 3239, 3566, 3607, 3616, 3729, 3939, 4062], 'Kohne': [655], 'A.C.': [656], 'Renkawitz': [657, 931], 'R.': [658, 817, 893, 922, 932, 1074, 1310, 1630, 1664, 3930, 4019, 4053], 'EMBO': [659, 1719, 1942, 2440], 'J.': [660, 823, 924, 926, 933, 1070, 1165, 1333, 1438, 1628, 1720, 1807, 1811, 1920, 1943, 2048, 2052, 2114, 2118, 2416, 2441, 3373, 3377, 3436, 3440, 4017], '1992;': [661], '11:': [662, 1234, 1961], '1015-1023Crossref': [663], '(239)': [666], 'Although': [669], 'mechanisms': [671], 'repression': [674, 696, 1031, 1244, 1464], 'functions': [677, 2020, 2165], 'not': [679, 3285, 3329, 3833, 3878, 3993, 4184], 'fully': [680], 'understood,': [681], 'growing': [683], 'list': [684], 'cofactors': [686, 764, 843], 'interact': [688, 3272, 3320, 3330, 3345, 3690, 3914, 3954, 4102], 'modulate': [691, 1500], 'properties': [697], 'have': [701, 844, 2102, 2394, 3423, 3535], 'been': [702, 845, 2103, 2395, 3214, 3424], 'Refs.7Horwitz': [707], 'K.B.': [708], 'Jackson': [709], 'T.A.': [710], 'Bain': [711], 'D.L.': [712, 1736], 'Richer': [713], 'J.K.': [714, 1691], 'Takimoto': [715], 'G.S.': [716], 'Tung': [717], 'L.': [718, 1194, 1624, 1840, 1939, 4013], 'Mol.': [719, 978, 1042, 1098, 1122, 1231, 1762], 'Endocrinol.': [720, 979, 1043, 1099, 1232], '1996;': [721, 962, 1100, 1125, 1314, 1339, 1397, 1416, 1613, 1644, 1674, 1694, 1721, 1746, 2422, 2442, 2775, 2905, 2935, 2985, 3940, 4033, 4063], '10:': [722, 1101], '1167-1177Crossref': [723], '(837)': [726], '8Glass': [729], 'C.K.': [730, 905, 1082, 1117, 1181, 1640, 1817, 2058, 2124, 3383, 3446, 4029], 'Rose': [731, 1178, 1637, 1808, 2049, 2115, 3374, 3437, 4026], 'D.W.': [732, 1179, 1638, 1809, 2050, 2116, 3375, 3438, 4027], 'Rosenfeld': [733, 902, 1083, 1118, 1182, 1641, 1818, 2059, 2125, 3384, 3447, 4030], 'M.G.': [734, 876, 903, 1084, 1119, 1183, 1642, 1819, 2060, 2076, 2126, 2143, 3385, 3402, 3448, 3465, 4031], 'Curr.': [735, 1542], 'Opin.': [736], 'Biol.': [738, 934, 1124, 1543, 1764, 1921], '1997;': [739, 756, 1185, 1210, 1233, 1256, 1268, 1368, 1452, 1517, 1544, 1765, 1798, 1821, 1848, 1960, 2039, 2062, 2078, 2128, 2145, 2463, 3240, 3387, 3404, 3450, 3467, 3567, 3730], '9:': [740, 981, 1045], '222-232Crossref': [741], '(601)': [744], '9Chen': [747, 1359], 'J.D.': [748, 950, 987, 1051, 1230, 1360, 1790, 2031, 2399, 2455, 2763, 2893, 2923, 2973, 3232, 3559, 3722], 'Li': [749, 1361], 'H.L.': [750, 1362], 'Crit.': [751, 1363], 'Rev.': [752, 1364], 'Eukaryotic': [753, 1365], 'Gene': [754, 1366, 1692], 'Exp.': [755, 1367], '(in': [757, 1369], 'press)PubMed': [758, 1370], 'involvement': [762, 1559], 'signaling': [768], 'postulated': [771], 'when': [772, 3863], 'members': [773, 1910], 'superfamily': [778], 'were': [779, 1020, 1137, 2312, 2339, 2520, 2533, 2569, 2599, 2624, 2631, 2661, 2679, 2726, 2740, 2752, 2789, 2824, 2847, 2852, 2862, 2880, 2887, 2918, 2954, 2996, 3033, 3046, 3070, 3085, 3110, 3179, 3198, 3507, 3625, 3964, 4149, 4199, 4253], 'cross-react': [782], 'each': [784, 2916, 3856, 4114], 'other': [785, 813, 2392, 3280, 3995], 'functionally': [786], '(10Meyer': [787], 'Gronemeyer': [789, 1717, 2438], 'H.': [790, 855, 952, 1224, 1541, 1718, 1730, 1755, 1786, 1830, 2027, 2439, 2451, 2496, 3228, 3555, 3605, 3718], 'Turcotte': [791], 'Bocquel': [793], 'Tasset': [795], 'D.': [796, 920, 1198, 1836, 2494, 3603], '1989;': [800], '57:': [801], '433-442Abstract': [802], '(444)': [808], 'Scholar)': [810, 969, 2515, 2942, 3624], 'factors': [815, 1511], '(11Schüle': [816], 'Mangelsdorf': [820], 'Bolado': [822], 'Pike': [824], 'J.W.': [825], '1990;': [829], '61:': [830], '497-504Abstract': [831], '(426)': [837], 'Currently,': [840], 'several': [841, 3825], 'biochemically': [847], '(12Halachmi': [848], 'S.': [849, 872, 882, 899, 928, 960, 1095, 1605, 1672, 1744, 1796, 1815, 2037, 2056, 2074, 2122, 2141, 2461, 2506, 2773, 2903, 2933, 2983, 3238, 3381, 3400, 3444, 3463, 3565, 3615, 3728, 3938, 4061], 'Marden': [850], 'E.': [851, 1175, 1953, 2072, 2139, 3398, 3461], 'Martin': [852], 'MacKay': [854], 'Abbondanza': [856], 'Brown': [858, 900], 'Science.': [860, 1591], '1994;': [861, 884], '264:': [862], '1455-1458Crossref': [863], '(566)': [866], '13Cavailles': [869], 'V.': [870, 1410], 'Dauvois': [871], 'Danielian': [873], 'P.S.': [874], 'Parker': [875, 2075, 2142, 3401, 3464], 'Proc.': [877, 955, 1667, 1739, 1791, 2032, 2456, 2501, 2768, 2898, 2928, 2978, 3233, 3560, 3610, 3723, 3933, 4056], 'Natl.': [878, 956, 1668, 1740, 1792, 2033, 2457, 2502, 2769, 2899, 2929, 2979, 3234, 3561, 3611, 3724, 3934, 4057], 'Acad.': [879, 957, 1669, 1741, 1793, 2034, 2458, 2503, 2770, 2900, 2930, 2980, 3235, 3562, 3612, 3725, 3935, 4058], 'Sci.': [880, 958, 1670, 1742, 1794, 2035, 2459, 2504, 2771, 2901, 2931, 2981, 3236, 3563, 3613, 3726, 3936, 4059], 'U.': [881, 959, 1671, 1743, 1795, 2036, 2460, 2505, 2772, 2902, 2932, 2982, 3237, 3564, 3614, 3727, 3937, 4060], '91:': [885], '10009-10013Crossref': [886], '(340)': [889], '14Kurokawa': [892], 'Soderstrom': [894, 1079, 1160], 'Horlein': [896, 1114], 'Halachmi': [898], 'Glass': [904, 1081, 1116, 1180, 1639, 1816, 2057, 2123, 3382, 3445, 4028], 'Nature.': [906, 990, 1054, 1085, 1184, 1255, 1313, 1338, 1396, 1451, 1820, 2061, 2077, 2127, 2144, 2402, 2421, 3386, 3403, 3449, 3466], '377:': [908, 992, 1056, 1087, 2404], '451-454Crossref': [909], '(486)': [912], '15Eggert': [915], 'Mows': [917], 'C.C.': [918, 2476], 'Tripier': [919], 'Arnold': [921], 'Michel': [923], 'Nickel': [925], 'Schmidt': [927], 'Chem.': [935, 1922], '270:': [937, 1593, 1924], '30755-30759Abstract': [938], '(45)': [946], '16Fondell': [949], 'Ge': [951, 1540], 'Roeder': [953, 1514], 'R.G.': [954, 1515], '93:': [963, 1675, 1747, 2776, 2906, 2936, 2986, 3941, 4064], '8329-8333Crossref': [964], '(462)': [967], 'genetically': [971], '(17Seol': [972, 1036], 'W.': [973, 1037, 1513], 'Choi': [974, 1038], 'H.S.': [975, 1039], 'Moore': [976, 1040], 'D.D.': [977, 1041], '72-85Crossref': [982, 1046], '18Chen': [986, 1050], '454-457Crossref': [993, 1057, 2405], '(1712)': [996, 1060, 1091, 2408], 'particular,': [1000, 3775], 'two': [1001], 'proteins': [1003, 1026, 1303, 1354, 1507, 1865, 2025, 2519, 2532, 2568, 2623, 2678], 'known': [1004, 1581, 1706, 1780, 2090], 'as': [1005, 1022, 1300, 1707, 2091, 2759, 2889, 2920, 2970], 'silencing': [1007], 'mediator': [1008], '(SMRT)': [1013], 'corepressor': [1018, 1145, 1288, 1379], '(N-COR)': [1019], 'TR-': [1023], 'RAR-interacting': [1025], 'can': [1028, 2232, 3343, 3882, 3913, 3952, 4167], 'assist': [1029], 'unliganded': [1034, 3349], '19Horlein': [1063], 'A.J.': [1064, 1393], 'Naar': [1065], 'A.M.': [1066], 'Heinzel': [1067, 1625, 4014], 'T.': [1068, 1155, 1312, 1395, 1626, 2358, 2696, 4015], 'Torchia': [1069, 1164, 1627, 4016], 'Gloss': [1071, 1631, 4020], 'Kurokawa': [1073, 1629, 4018], 'Ryan': [1075], 'Kamei': [1077, 1812, 2053, 2119, 3378, 3441], 'Y.': [1078, 1337, 1414, 1537, 1609, 1622, 1683, 1813, 1844, 2054, 2120, 2366, 2420, 2704, 3379, 3442, 4011], '397-404Crossref': [1088], '20Sande': [1094], 'Privalsky': [1096, 1841], 'M.L.': [1097, 1842, 1941], '813-825Crossref': [1102], '(210)': [1105], '21Zamir': [1108], 'I.': [1109], 'Harding': [1110], 'H.P.': [1111], 'Atkins': [1112], 'G.B.': [1113], 'Lazar': [1120], 'M.A.': [1121], '16:': [1126], '5458-5465Crossref': [1127], '(199)': [1130], 'Recently,': [1133], 'SMRT': [1134, 1246], 'N-COR': [1136, 1248], 'form': [1140, 2233], 'mSin3': [1146], 'deacetylases': [1150], 'HDAC1': [1151], 'mRPD3': [1153], '(22Heinzel': [1154], 'Lavinsky': [1156], 'Mullen': [1158], 'T.M.': [1159], 'Laherty': [1162], 'C.D.': [1163, 1436], 'Yang': [1166, 1532, 2365, 2703], 'W.M.': [1167], 'Brard': [1168], 'Ngo': [1170], 'S.D.': [1171], 'Davie': [1172], 'J.R.': [1173], 'Seto': [1174], 'Eisenman': [1176], 'R.N.': [1177], '387:': [1186, 1257, 1822, 2063, 2079, 2129, 2146, 3388, 3405, 3451, 3468], '43-48Crossref': [1187], '(1084)': [1190], '23Nagy': [1193], 'Kao': [1195], 'H.Y.': [1196], 'Chakravarti': [1197, 1835, 2493, 3602], 'Lin': [1199, 1633, 1831, 4022], 'R.J.': [1200, 1832], 'Hassig': [1201], 'C.A.': [1202, 1440, 1919], 'Ayer': [1203], 'D.E.': [1204], 'Schreiber': [1205], 'S.L.': [1206], '89:': [1211, 1269], '373-380Abstract': [1212], '(1107)': [1220, 1826, 2067, 2133, 3392, 3455], '24Li': [1223], 'Leo': [1225], 'Schroen': [1227], 'Chen': [1229, 1789, 2030, 2361, 2454, 2699, 3231, 3558, 3721], '2025-2037Crossref': [1235], '(109)': [1238], 'suggesting': [1241, 1557, 2153, 2202, 2244, 3292, 4083], 'might': [1249, 1468, 2158, 3843], 'involve': [1250], 'deacetylation': [1252], '(25Wolffe': [1253], 'A.P.': [1254, 1539], '16-17Crossref': [1258], '(254)': [1261], 'Scholar,26Pazin': [1263], 'M.J.': [1264, 1588, 1759], 'Kadonaga': [1265], 'J.T.': [1266], '325-328Abstract': [1270], '(772)': [1278], 'Hormone': [1281], 'thought': [1284], 'dissociate': [1286], 'from': [1290, 2524, 3040, 3786, 3885], 'receptors,': [1292, 2243, 3484], 'allowing': [1293], 'recruit': [1297, 4091], 'coactivators,': [1298], 'CREB/E1A-binding': [1302], '(CBP/p300)': [1304], '27Janknecht': [1309], 'Hunter': [1311], '383:': [1315], '22-23Crossref': [1316], '(348)': [1319], 'Scholarand': [1321], 'references': [1322], 'therein),': [1323], 'p300/CBP-associated': [1325], '(P/CAF;': [1327], 'Ref.28Yang': [1328], 'X.J.': [1329, 2412], 'Ogryzko': [1330, 1534, 2413], 'V.V.': [1331, 1406, 1535, 2414], 'Nishikawa': [1332, 2415], 'Howard': [1334, 1411, 2417], 'B.H.': [1335, 1412, 2418], 'Nakatani': [1336, 1413, 1536, 1843, 2419], '382:': [1340, 2423], '319-324Crossref': [1341, 2424], '(1317)': [1344, 2427], 'steroid/nuclear': [1349, 1569], '(SRC)': [1352], 'contrast': [1374, 3764], 'complexes,': [1380], 'all': [1381, 2022], 'these': [1383, 1494, 1864, 2098, 2155, 2167, 2214, 2252, 2289, 2386, 3830, 3858, 3900], 'putative': [1384], 'contain': [1386, 3297], 'intrinsic': [1387], 'acetyltransferase': [1389], '(HAT)': [1390], 'activity': [1391, 3038], '(29Bannister': [1392], 'Kouzarides': [1394], '384:': [1398], '641-643Crossref': [1399], '(1533)': [1402], '30Ogryzko': [1405], 'Schiltz': [1407, 1833], 'R.L.': [1408, 1834], 'Russanova': [1409], '87:': [1417], '953-959Abstract': [1418], '(2402)': [1426], '31Spencer': [1429], 'T.E.': [1430], 'Jenster': [1431], 'Burcin': [1433], 'M.M.': [1434], 'Allis': [1435], 'Zhou': [1437, 1661, 3927, 4050], 'Mizzen': [1439], 'McKenna': [1441], 'N.J.': [1442], 'Onate': [1443], 'S.A.': [1444, 1584], 'Tsai': [1445, 1447, 1585, 1587], 'S.Y.': [1446, 1586], 'M.-J.': [1448], "O'Malley": [1449, 1589], 'B.W.': [1450, 1590], '389:': [1453], '194-198Crossref': [1454], '(1066)': [1457], 'Therefore,': [1460, 2288], 'determined': [1470, 2753, 2997], 'relative': [1473], 'acetylation': [1474], 'level': [1475, 4339], 'targets': [1477, 1562], 'corepressors.': [1484], 'Recent': [1485], 'findings': [1486], 'that,': [1489], 'addition': [1491, 1980], 'histones,': [1493], 'acetylate': [1498], 'property': [1504], 'activator': [1506], 'or': [1508, 2199, 2324, 2745, 3056, 3279, 4093], 'general': [1509, 3917], '(32Gu': [1512], '90:': [1518, 1849], '595-606Abstract': [1519], '(2177)': [1527], '33Imhof': [1530], 'X.-J.': [1533], 'Wolffe': [1538], '7:': [1545, 2376, 2714], '689-692Abstract': [1546], '(535)': [1554], 'multiple': [1561, 2306], 'pathways': [1564], 'regulation.': [1567], '(SRC-1;': [1579], 'asNCoA-1)': [1582], '(34Oñate': [1583], '1354-1357Crossref': [1594], '(2058)': [1597], '35Takeshita': [1600], 'Yen': [1602], 'P.M.': [1603], 'Misiti': [1604], 'Cardona': [1606], 'G.R.': [1607], 'Liu': [1608], 'Chin': [1610], 'W.W.': [1611], 'Endocrinology.': [1612], '137:': [1614], '3594-3597Crossref': [1615], '(147)': [1618], '36Kamei': [1621], 'Xu': [1623, 4012], 'S.C.': [1634, 4023], 'Heyman': [1635, 4024], 'R.A.': [1636, 4025], '85:': [1645, 4034], '403-414Abstract': [1646, 4035], '(1926)': [1654, 4043], '37Yao': [1657, 4046], 'T.P.': [1658, 3924, 4047], 'Ku': [1659, 3925, 4048], 'N.': [1662, 3928, 4051], 'Scully': [1663, 3929, 4052], 'Livingston': [1665, 3931, 4054], 'D.M.': [1666, 2070, 2137, 3396, 3459, 3932, 4055], '10626-10631Crossref': [1676, 3942, 4065], '(395)': [1679, 3945, 4068], '38Zhu': [1682], 'Qi': [1684], 'Calandra': [1686], 'Rao': [1688], 'M.S.': [1689], 'Reddy': [1690], 'Expr.': [1693], '6:': [1695], '185-195PubMed': [1696], '2': [1703, 3761, 3806, 3894], '(TIF2,': [1704], 'GRIP1)': [1708], '(39Voegel': [1709], 'J.J.': [1710, 2431], 'Heine': [1711, 2432], 'M.J.S.': [1712, 2433], 'Zechel': [1713, 2434], '15:': [1722, 2443], '3667-3675Crossref': [1723, 2444], '(952)': [1726, 2447], '40Hong': [1729], 'Kohli': [1731, 1756], 'Trivedi': [1733], 'Johnson': [1735], 'Stallcup': [1737, 1760], 'M.R.': [1738, 1761], '4948-4952Crossref': [1748], '(614)': [1751], '41Hong': [1754], 'Garabedian': [1758], '17:': [1766], '2735-2744Crossref': [1767], '(497)': [1770], '(RAC3,': [1778], 'asACTR,': [1781], 'p/CIP,': [1782], 'AIB1)': [1784], '(42Li': [1785, 2026, 3227, 3554, 3717], 'Gomes': [1787, 2028, 2452, 3229, 3556, 3719], 'P.J.': [1788, 2029, 2453, 3230, 3557, 3720], '94:': [1799, 2040, 2464, 3241, 3568, 3731], '8479-8484Crossref': [1800, 2041, 2465, 3242, 3569, 3732], '(504)': [1803, 2044, 2468, 3245, 3572, 3735], '43Torchia': [1806, 2047], 'Inostroza': [1810, 2051, 2117, 3376, 3439], 'Westin': [1814, 2055, 2121, 3380, 3443], '677-684Crossref': [1823, 2064, 2130, 3389, 3452], '44Chen': [1829], 'Nash': [1837], 'Nagy': [1839], '569-580Abstract': [1850], '(1268)': [1858], 'Sequence': [1861], 'comparison': [1862], 'reveals': [1866], 'they': [1868, 3842], 'share': [1869], 'overall': [1871], 'identity': [1872], 'about': [1874, 3188], '40%,': [1875], 'but': [1876, 1967, 3877, 3992, 4183, 4277, 4356], 'striking': [1878], 'similarity': [1879], 'at': [1880, 2666, 2791, 2830, 2854, 3141, 3156, 3175, 3184, 3752, 3770, 4266, 4278, 4298, 4312, 4336], 'helix-loop-helix': [1884], '(bHLH)': [1885], 'receptor-single': [1889], 'minded': [1890], '(PAS)': [1891], '“A”': [1892], '“B”': [1894], 'domains.': [1895], 'bHLH-PAS': [1897, 1983], 'protein-protein': [1901, 2108], 'interactions,': [1902], 'heterodimerization,': [1903], 'target': [1905], 'selection': [1907], 'many': [1909], '(45Swanson': [1914], 'H.I.': [1915], 'Chan': [1916], 'W.K.': [1917], 'Bradfield': [1918], '26292-26302Abstract': [1925], '(321)': [1933], '46Lindebro': [1936], 'M.C.': [1937], 'Poellinger': [1938], 'Whitelaw': [1940], '14:': [1945], '3528-3539Crossref': [1946], '(163)': [1949], '47Zelzer': [1952], 'Wappner': [1954], 'Shilo': [1956], 'B.-Z.': [1957], 'Genes': [1958, 2373, 2711], 'Dev.': [1959, 2374, 2712], '2065-2079Crossref': [1962], '(124)': [1964], 'role': [1969, 2162, 2298], 'SRC': [1975, 2024], 'remains': [1977], 'unclear.': [1978], 'domain,': [1984], 'seven': [1985], '(L': [1992], 'indicates': [1993], 'hydrophobic': [1994], 'residue)': [1995], 'core': [1996], 'consensus': [1997], 'sequence': [1998], 'flanked': [1999], 'charged': [2001], 'residues': [2004], 'central': [2009, 3219, 3758], 'mediates': [2012, 3525], 'Scholar,48Heery': [2069], 'Kalkhoven': [2071, 2138, 3397, 3460], 'Hoare': [2073, 2140, 3399, 3462], '733-736Crossref': [2080, 2147, 3406, 3469], '(1772)': [2083, 2150, 3409, 3472], '(LCDs).': [2095], 'Three': [2096], 'SRC-1': [2101, 3120, 3431, 3912, 3998, 4260, 4294], 'shown': [2104], 'direct': [2107, 3428], 'liganded': [2111, 3274, 3510], '(43Torchia': [2113, 3372, 3435], '48Heery': [2136, 3395, 3458], 'play': [2159], 'important': [2161, 2297], 'further': [2173, 3476, 3577, 3693, 3780], 'different': [2188, 3049, 4247], 'differentially': [2192], 'either': [2195, 2315], 'activation,': [2201], 'importance': [2204], 'flanking': [2207], 'sequences': [2208, 3270], 'determining': [2210], 'motifs.': [2216, 3828], 'interacts': [2221, 3983, 3999], 'CBP': [2224, 2240, 3920, 3987, 4001, 4081, 4092, 4105, 4144, 4172, 4194, 4238], 'its': [2226, 3492, 3687, 4094], 'bridge': [2235, 4168], 'between': [2239, 3221, 3430, 3480, 3529, 3541, 3655, 3814, 4171, 4214], 'one': [2246, 4085], 'mechanism': [2247, 2279], 'cofactors.': [2258], 'transcript': [2266], 'retinoic': [2271], 'acid,': [2272], 'demonstrating': [2273, 3519], 'new': [2275], 'perhaps': [2277], 'independent': [2278, 3644], 'coactivation': [2282], 'strongly': [2291, 3799, 3984], 'plays': [2295], 'utilization': [2304], 'mechanisms.': [2307], 'individual': [2309], 'fragments': [2311, 3315, 3324, 3794, 3988, 4002, 4145, 4195], 'obtained': [2313], 'restriction': [2316], 'enzyme': [2317], 'digestion': [2318], 'full-length': [2321, 3969, 4154], 'clone': [2323], 'PCR': [2326], 'amplification': [2327], 'synthetic': [2329], 'primers': [2330], 'harboring': [2331], 'suitable': [2332], 'cloning': [2333], 'sites.': [2334], 'motif': [2337], 'constructs': [2338, 2387, 2393, 2725, 2739], 'generated': [2340, 2625, 2727, 3486], 'subcloning': [2342], 'annealed': [2343], 'double-stranded': [2344], 'oligonucleotides': [2345], 'encoding': [2346], 'specified': [2348], 'amino': [2349, 3222, 3254, 3294, 3313, 3714, 3776, 3815], 'acids': [2350, 3223, 3255, 3295, 3715, 3777, 3816, 3975], 'into': [2351, 2633, 2956], 'yeast': [2353, 2684, 2692, 3289, 3742, 3891], 'expression': [2354, 3804, 4242, 4345, 4360, 4376, 4389], 'vector': [2355, 2747], 'pAS1': [2356], '(49Durfee': [2357, 2695], 'Becherer': [2359, 2697], 'P.L.': [2362, 2700], 'Yeh': [2363, 2701], 'S.H.': [2364, 2702], 'Kilburn': [2367, 2705], 'A.E.': [2368, 2706], 'Lee': [2369, 2707], 'W.H.': [2370, 2708], 'Elledge': [2371, 2709], 'S.J.': [2372, 2710], '1993;': [2375, 2713], '555-569Crossref': [2377, 2715], '(1299)': [2380, 2718], 'Detailed': [2383], 'information': [2384], 'regarding': [2385], 'available': [2389], 'athttp://146.189.26.74/.': [2390], 'All': [2391, 2844], 'previously': [2396, 2761, 2891, 3215, 3537, 3711], 'published': [2397], '(18Chen': [2398], '28Yang': [2411], '39Voegel': [2430], '42Li': [2450], '50Umesono': [2471], 'Murakami': [2473], 'K.K.': [2474], 'Thompson': [2475], '1991;': [2480], '65:': [2481], '1255-1266Abstract': [2482], '(1497)': [2488], '51Schulman': [2491], 'I.G.': [2492, 3601], 'Juguilon': [2495, 3604], 'Romo': [2497, 3606], '92:': [2509, 3618], '8288-8292Crossref': [2510, 3619], '(91)': [2513, 3622], '.': [2516], 'GST': [2517], 'fusion': [2518, 2531, 2724, 2738, 3489], 'overexpressed': [2521], 'purified': [2523], 'DH5α': [2525], 'on': [2527, 2535, 3095, 3547, 3630], 'glutathione-agarose': [2528], 'beads.': [2529], 'separated': [2534, 3094], 'denaturing': [2536], 'gels': [2538], '(SDS-polyacrylamide': [2539], 'gel': [2540, 3099], 'electrophoresis)': [2541], 'electroblotted': [2543], 'onto': [2544, 3106], 'nitrocellulose': [2545, 3107], 'filters': [2546, 2598, 2660], 'transfer': [2549], 'buffer': [2550, 2582, 2604, 2614, 2636, 3123], '(25': [2551, 2583], 'mm': [2552, 2557, 2584, 2589, 2592, 2595, 2638, 2643, 2646, 2649, 2657, 3014, 3135, 3139], 'Tris-HCl,': [2553], 'pH': [2554, 2586, 2640, 3028, 3142], '8.3,': [2555], '192': [2556], 'glycine,': [2558], '0.01%': [2559], 'SDS).': [2560], 'After': [2561, 2876], 'denaturation': [2562], '6m': [2564], 'guanidine': [2565, 2575], 'hydrochloride,': [2566], 'renatured': [2570], 'stepwise': [2572], 'dilution': [2573], 'hydrochloride': [2576], '0.187': [2578], 'm': [2579, 3102, 3132, 3171], 'HB': [2581, 2613], 'Hepes,': [2585, 2639], '7.7,': [2587, 2641], '25': [2588], 'NaCl,': [2590, 3133], '5': [2591, 3013], 'MgCl2,': [2593, 2650], '1': [2594, 2656, 3138, 3277, 3335, 3517, 3660], 'dithiothreitol).': [2596, 2658], 'then': [2600, 2609, 3304, 4157], 'saturated': [2601], 'blocking': [2603], '(5%': [2605], 'nonfat': [2606], 'milk': [2607, 2611], '1%': [2610, 2654, 3097], 'plus': [2615, 3080, 3169], '0.05%': [2616, 2651], 'Nonidet': [2617, 2652], 'P-40).': [2618], 'vitro': [2620, 3499], 'translated': [2621], '35S-labeled': [2622, 4159], 'reticulocyte': [2627], 'lysate': [2628], '(Promega)': [2629], 'diluted': [2632], 'hybridization': [2635, 2674, 3122], '(20': [2637], '75': [2642], 'KCl,': [2644], '0.1': [2645, 3026, 3149], 'EDTA,': [2647], '2.5': [2648], 'P-40,': [2653], 'milk,': [2655], 'allowed': [2662], 'hybridize': [2664], 'overnight': [2665], '4': [2667, 4290], '°C': [2668, 2793, 3158, 3186], 'followed': [2669], 'washes': [2672], 'buffer.': [2675], 'bound35S-labeled': [2677], 'detected': [2680], 'autoradiography.': [2682], 'two-hybrid': [2685, 3290, 3309], 'assay': [2686, 2758, 2962, 2969, 3009], 'carried': [2688], 'out': [2689], 'Y190': [2693], 'strain': [2694], 'GAL4': [2722, 2734, 3867], 'DBD': [2723], 'pGBT9': [2730], 'vector,': [2731], '(AD)': [2737], 'made': [2741], 'pGAD424': [2744], 'pACTII': [2746], '(CLONTECH).': [2748], 'β-galactosidase': [2750, 2883, 2950, 2968, 3037, 3789], 'activities': [2751, 2886, 2995, 3032], 'ONPG': [2756], 'liquid': [2757], 'described': [2760, 2890, 2921, 2971], '(52Chen': [2762, 2892, 2922, 2972], '7567-7571Crossref': [2777, 2907, 2937, 2987], '(222)': [2780, 2910, 2940, 2990], 'African': [2783], 'green': [2784], 'monkey': [2785], 'kidney': [2786, 4288], 'CV-1': [2787], 'grown': [2790], '37': [2792], '5%': [2795], 'CO2in': [2796], "Dulbecco's": [2797], 'modified': [2798], "Eagle's": [2799], 'medium': [2800, 2869], 'supplemented': [2801], '10%': [2803], 'resin-charcoal': [2804], 'stripped': [2805], 'fetal': [2806], 'bovine': [2807], 'serum,': [2808], '50': [2809, 2814], 'units/ml': [2810], 'penicillin': [2811], 'G,': [2812], 'μg/ml': [2815], 'streptomycin': [2816], 'sulfate.': [2817], 'One': [2818], 'day': [2819], 'prior': [2820], 'transfection,': [2822, 2860], 'plated': [2825], '24-well': [2827], 'culture': [2828], 'dishes': [2829], 'density': [2832], '50,000': [2834], 'cells/well.': [2835], 'Transfection': [2836], 'performed': [2838, 2848], 'standard': [2840], 'calcium': [2841], 'phosphate': [2842], 'precipitation.': [2843], 'transfection': [2845], 'experiments': [2846], 'triplicate': [2850], 'replicated': [2853], 'least': [2855], 'once.': [2856], 'Twelve': [2857], 'hours': [2858], 'after': [2859], 'washed': [2863], 'PBS': [2865], 'refed': [2867], 'fresh': [2868], 'indicated': [2872], 'amounts': [2873], 'ligand.': [2875], '30': [2877], 'h,': [2878], 'harvested': [2881], 'luciferase': [2885, 2947, 2961, 2994, 3031, 3888], 'assayed': [2888], 'Transfected': [2913], 'well': [2917], 'lysed': [2919], 'processed': [2944], 'assays.': [2951], 'lysates': [2953], 'transferred': [2955], '96-well': [2957, 2964], 'microlite': [2958], 'plates': [2959, 2966], 'microtiter': [2965, 3001], 'MLX': [3000], 'plate': [3002], 'luminometer': [3003], '(Dynex)': [3004], 'using': [3005, 3087], '100': [3006, 3019], 'μl': [3007, 3020], 'solution': [3010, 3023], '(0.1': [3011], 'mKPO4,': [3012, 3027], 'ATP,': [3015], '10': [3016, 3134], 'mmMgCl2)': [3017], 'luciferin': [3022], '(0.01md-luciferin': [3024], '7.8).': [3029], 'normalized': [3034], 'cotransfected': [3042], 'pCMX-βGal': [3043], 'plasmid.': [3044], 'Cells': [3045], 'treated': [3047, 3071], 'concentrations': [3050], 'atRA': [3052], '(0,': [3053], '10,': [3054], '100,': [3055], '1000': [3057], 'nm)': [3058], 'period': [3061], '12': [3063], 'h.': [3064, 3190], 'control': [3067], 'group,': [3068], 'equal': [3074], 'volume': [3075], 'solvent': [3077], '(80%': [3078], 'EtOH': [3079], '20%': [3081], 'DMSO).': [3082], 'Total': [3083], 'RNAs': [3084], 'isolated': [3086], 'RNA': [3089], 'isolation': [3090], 'kit': [3091], '(RNAzol)': [3092], 'agarose': [3098], '2.2': [3101], 'formaldehyde': [3103], 'blotted': [3105], 'filters.': [3108], 'Filters': [3109, 3178], 'hybridized': [3111, 3202], 'random-primed32P-labeled': [3113], 'probes': [3115], 'RAC3,TIF2,': [3118], '(50%': [3124], 'formamide,': [3125], '5×': [3126], 'SSPE': [3127, 3129], '(1×': [3128], '0.18': [3131], 'NaPO4,': [3136], 'EDTA': [3140], '7.7),': [3143], '2×': [3144], "Denhardt's": [3145], 'solution,': [3146], '0.1%': [3147], 'SDS,': [3148], 'mg': [3150], 'sheared': [3152], 'herring': [3153], 'sperm': [3154], 'DNA/ml)': [3155], '42': [3157], 'overnight.': [3159], 'final': [3161], 'wash': [3162], '1×': [3165], 'SSC': [3166], '(0.15m': [3167], 'NaCl': [3168], '0.015': [3170], 'sodium': [3172], 'citrate)-0.1%': [3173], 'SDS': [3174], '65': [3176], '°C.': [3177], 'exposed': [3180], 'x-ray': [3182], 'film': [3183], '−70': [3185], '24': [3189], 'human': [3192, 3598, 4248, 4369], 'tissue': [3193], 'cell': [3196], 'blots': [3197], 'purchased': [3199], 'fromCLONTECH': [3200], 'according': [3203], "manufacturer's": [3205], 'protocols.': [3206], 'has': [3213], 'located': [3216, 3712, 3751], 'within': [3217, 3592, 3713], '401': [3224], '1204': [3226], 'Here,': [3248, 3575], 'show': [3250], 'deletion': [3252, 3781], '507–1017': [3256, 3296], 'eliminates': [3257], 'rest': [3264], 'cannot': [3271, 3783], '(Fig.': [3276, 3334, 3516, 3659, 3760, 3805, 3893, 3977, 4139, 4180, 4289], 'A)': [3278], 'class': [3281], 'II': [3282], '(data': [3284], 'shown)': [3286], 'system,': [3291, 3310], 'interacting': [3299], 'confirmed': [3305], 'mammalian': [3308], '401–800': [3316, 3365, 3778], '613–752': [3318, 3341], 'whereas': [3323, 3360, 3791], '401–695': [3325], '401–624': [3327], 'do': [3328], 'B).': [3336, 3895], 'significantly': [3346], 'receptor,': [3350], 'only': [3355], 'slightly': [3356], 'enhanced': [3357], 'ligand-dependent.': [3367], 'Coincident': [3368], 'previous': [3370, 4008], 'studies': [3371], '(RID)': [3415], 'motifs,': [3421], 'implicated': [3425], 'mediating': [3427], 'To': [3475], 'confirm': [3477, 4229], 'interactions': [3479, 3506, 3967, 4117, 4213], 'RAC3-RID': [3481], 'GST-RID': [3488], 'analyzed': [3491, 3626, 3851, 3965], 'blot': [3503], 'analyses.': [3504], 'Significant': [3505], 'observed': [3508], 'estrogen': [3514], 'C),': [3518], 'RID': [3522], 'indeed': [3524], 'depends': [3546], 'presence': [3549, 4177], 'intact': [3552], 'AF2-AD': [3553, 3594, 3645, 3666, 3683], 'tested': [3578, 3949], 'whether': [3579, 3950, 4113], 'functionper': [3582], 'se': [3583], 'required': [3585, 3834], 'Several': [3589], 'point': [3590, 3646], 'helix': [3595, 3684], 'RXRα': [3599], '(51Schulman': [3600], 'their': [3628], 'effects': [3629], 'RAC3.': [3633, 3910], 'disruption': [3637], '(F450A,': [3648], 'F450P,': [3649], 'ML454A)': [3651], 'abolishes': [3652], 'RXR': [3658], 'D).': [3661, 4141], 'contrast,': [3663], 'neutral': [3665], 'mutation': [3667], '(M452A)': [3668], 'permits': [3669], 'strong': [3671], 'correlates': [3685], 'ability': [3688, 4098], 'supporting': [3694], 'hypothesis': [3696], 'AF-2-dependent': [3701], 'coactivator.': [3704], 'AD': [3707, 3747, 4088], '401–1204': [3716], 'Further': [3738], 'deletional': [3739], 'analyses': [3740], 'reveal': [3744], 'C': [3754, 3989, 4003, 4146, 4196], 'terminus': [3755], 'A),': [3762], 'N': [3772], 'terminus.': [3773], 'mutants': [3782], 'activate': [3784, 3883], 'Gal4-dependent': [3788, 3887], 'reporter,': [3790], '982–1204,': [3795], '982–1056,': [3796], '1017–1179': [3798], 'stimulate': [3800], 'reporter': [3802, 3889], 'A).': [3807], 'demonstrate': [3810, 4164], 'minimal': [3812], 'RAC3-AD': [3813, 3973, 4076], '1017': [3817], '1179.': [3819], 'Within': [3820], 'RAC3-AD,': [3822], 'Because': [3829, 3911], 'interaction,': [3838, 4082], 'speculate': [3840], 'fused': [3864], '(iv,': [3873], 'v,': [3874], 'vi),': [3876], 'ones,': [3881], 'indicate': [3898], 'p300': [3922], '(37Yao': [3923], 'CBP.': [3956], 'Serial': [3957], 'GST-CBP': [3958], 'fusions': [3959], 'covering': [3960], 'SRC-1-interacting': [3962], 'with35S-labeled': [3968], 'SRC-1,': [3971], '(amino': [3974], '1017–1179)': [3976], '3,A–C).': [3978], 'find': [3980, 4073], 'D': [3991, 4148, 4198], 'fragments.': [3996], 'Similarly,': [3997], 'D,': [4005], 'consistent': [4006], 'observations': [4009], '(36Kamei': [4010], 'alone': [4077], 'proteins.': [4096], 'prompted': [4109], 'us': [4110], 'test': [4112, 4136], 'pair': [4115], 'enough': [4119], 'developed': [4129], 'protocol': [4134], 'possibility': [4138], 'Briefly,': [4142], 'probed': [4150, 4200], 'unlabeled': [4153], 'E)': [4182], '(not': [4190], 'shown).': [4191], 'As': [4192], 'controls,': [4193], 'parallel': [4201], '35S-RAC3': [4203], 'and35S-RAR,': [4204], 'individually.': [4205], 'strength': [4211], 'CBP-RAC3': [4215], 'RAC3-RAR': [4217], 'link': [4221], 'together': [4222], 'utilizes': [4232], 'RAR.': [4240], 'patterns': [4243], 'examined': [4254], 'compared': [4256], 'those': [4258], 'TIF2.': [4262], 'high': [4267, 4299], 'levels': [4268, 4281, 4300, 4315, 4413], 'heart,': [4271, 4303], 'placenta,': [4272, 4305], 'skeletal': [4273, 4306], 'muscle,': [4274, 4307], 'pancreas': [4276, 4309], 'very': [4279, 4350], 'low': [4280, 4314], 'brain,': [4284, 4304], 'lung,': [4285, 4318], 'liver,': [4286, 4319], 'A,': [4291], 'left).': [4292], 'message': [4295, 4331, 4380], 'and,': [4310], 'again,': [4311], 'extremely': [4313], 'kidney.': [4321], 'Two': [4322], 'distinctSRC-1': [4323], 'messages': [4324], 'clearly': [4326], 'detectable,': [4327], 'larger': [4330], 'appears': [4332], 'higher': [4338], 'than': [4340], 'smaller': [4342], 'form.': [4343], 'pattern': [4346], 'TIF2': [4348], 'similar': [4351], 'highest': [4359, 4375], 'heart': [4363], 'instead': [4364], 'placenta.': [4366], 'cells,': [4371, 4395, 4401, 4406, 4421, 4426], "Burkitt's": [4383], 'lymphoma': [4384], 'Raji': [4385], 'substantial': [4388], 'epitheloid': [4392], 'carcinoma': [4393, 4430], 'HeLa': [4394], 'chronic': [4397], 'myelogenous': [4398], 'leukemia': [4399, 4419, 4424], 'K-562': [4400], 'colorectal': [4403], 'adenocarcinoma': [4404], 'SW480': [4405], 'melanoma': [4409], 'G361': [4410], 'cells.': [4411], 'Low': [4412], 'RAC3were': [4415], 'promyelocytic': [4418], 'HL-60': [4420], 'lymphoblastic': [4423], 'MOLT-4': [4425], 'lung': [4429], 'A5': [4431]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1993032659', 'counts_by_year': [{'year': 2022, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}], 'updated_date': '2024-12-12T03:53:19.678499', 'created_date': '2016-06-24'}