Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W1992957599', 'doi': 'https://doi.org/10.1080/14767050600852171', 'title': 'Endogenous inhibitors of nitric oxide and preeclampsia: A review', 'display_name': 'Endogenous inhibitors of nitric oxide and preeclampsia: A review', 'publication_year': 2006, 'publication_date': '2006-01-01', 'ids': {'openalex': 'https://openalex.org/W1992957599', 'doi': 'https://doi.org/10.1080/14767050600852171', 'mag': '1992957599', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/16966108'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1080/14767050600852171', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S1605907', 'display_name': 'The Journal of Maternal-Fetal & Neonatal Medicine', 'issn_l': '1476-4954', 'issn': ['1476-4954', '1476-7058'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320449', 'host_organization_name': 'Informa', 'host_organization_lineage': ['https://openalex.org/P4310320449'], 'host_organization_lineage_names': ['Informa'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5063057375', 'display_name': 'Femke Slaghekke', 'orcid': 'https://orcid.org/0000-0003-3952-0313'}, 'institutions': [{'id': 'https://openalex.org/I2801786986', 'display_name': 'Lyell McEwin Hospital', 'ror': 'https://ror.org/00pjm1054', 'country_code': 'AU', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801786986']}, {'id': 'https://openalex.org/I5681781', 'display_name': 'University of Adelaide', 'ror': 'https://ror.org/00892tw58', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I5681781']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Femke Slaghekke', 'raw_affiliation_strings': ['Department of Obstetrics and Gynaecology, Lyell McEwin Health Service, University of Adelaide, Australia'], 'affiliations': [{'raw_affiliation_string': 'Department of Obstetrics and Gynaecology, Lyell McEwin Health Service, University of Adelaide, Australia', 'institution_ids': ['https://openalex.org/I2801786986', 'https://openalex.org/I5681781']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035270534', 'display_name': 'Gus Dekker', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801786986', 'display_name': 'Lyell McEwin Hospital', 'ror': 'https://ror.org/00pjm1054', 'country_code': 'AU', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801786986']}, {'id': 'https://openalex.org/I5681781', 'display_name': 'University of Adelaide', 'ror': 'https://ror.org/00892tw58', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I5681781']}], 'countries': ['AU'], 'is_corresponding': True, 'raw_author_name': 'Gus Dekker', 'raw_affiliation_strings': ['Department of Obstetrics and Gynaecology, Lyell McEwin Health Service, University of Adelaide, Australia'], 'affiliations': [{'raw_affiliation_string': 'Department of Obstetrics and Gynaecology, Lyell McEwin Health Service, University of Adelaide, Australia', 'institution_ids': ['https://openalex.org/I2801786986', 'https://openalex.org/I5681781']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5068443543', 'display_name': 'Bill Jeffries', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2801786986', 'display_name': 'Lyell McEwin Hospital', 'ror': 'https://ror.org/00pjm1054', 'country_code': 'AU', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2801786986']}, {'id': 'https://openalex.org/I5681781', 'display_name': 'University of Adelaide', 'ror': 'https://ror.org/00892tw58', 'country_code': 'AU', 'type': 'education', 'lineage': ['https://openalex.org/I5681781']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Bill Jeffries', 'raw_affiliation_strings': ['Department of General Medicine, Lyell McEwin Health Service, University of Adelaide, Australia'], 'affiliations': [{'raw_affiliation_string': 'Department of General Medicine, Lyell McEwin Health Service, University of Adelaide, Australia', 'institution_ids': ['https://openalex.org/I2801786986', 'https://openalex.org/I5681781']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5035270534'], 'corresponding_institution_ids': ['https://openalex.org/I2801786986', 'https://openalex.org/I5681781'], 'apc_list': None, 'apc_paid': None, 'fwci': 0.463, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 25, 'citation_normalized_percentile': {'value': 0.434018, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 89, 'max': 90}, 'biblio': {'volume': '19', 'issue': '8', 'first_page': '447', 'last_page': '452'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10290', 'display_name': 'Pathophysiology and Management of Preeclampsia', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2729', 'display_name': 'Obstetrics and Gynecology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10290', 'display_name': 'Pathophysiology and Management of Preeclampsia', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2729', 'display_name': 'Obstetrics and Gynecology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11389', 'display_name': 'Maternal Morbidity Associated with Pregnancy and Childbirth', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2735', 'display_name': 'Pediatrics, Perinatology and Child Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12230', 'display_name': 'Management of Cardiovascular Diseases during Pregnancy', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/asymmetric-dimethylarginine', 'display_name': 'Asymmetric dimethylarginine', 'score': 0.9012478}, {'id': 'https://openalex.org/keywords/pathogenesis', 'display_name': 'Pathogenesis', 'score': 0.6593291}, {'id': 'https://openalex.org/keywords/preeclampsia', 'display_name': 'Preeclampsia', 'score': 0.477647}], 'concepts': [{'id': 'https://openalex.org/C2777218350', 'wikidata': 'https://www.wikidata.org/wiki/Q61335', 'display_name': 'Preeclampsia', 'level': 3, 'score': 0.92888904}, {'id': 'https://openalex.org/C2779877776', 'wikidata': 'https://www.wikidata.org/wiki/Q752685', 'display_name': 'Asymmetric dimethylarginine', 'level': 4, 'score': 0.9012478}, {'id': 'https://openalex.org/C519581460', 'wikidata': 'https://www.wikidata.org/wiki/Q207843', 'display_name': 'Nitric oxide', 'level': 2, 'score': 0.83436656}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.66186464}, {'id': 'https://openalex.org/C2780942790', 'wikidata': 'https://www.wikidata.org/wiki/Q372016', 'display_name': 'Pathogenesis', 'level': 2, 'score': 0.6593291}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.5651419}, {'id': 'https://openalex.org/C120770815', 'wikidata': 'https://www.wikidata.org/wiki/Q14859627', 'display_name': 'Vasodilation', 'level': 2, 'score': 0.56022185}, {'id': 'https://openalex.org/C16613235', 'wikidata': 'https://www.wikidata.org/wiki/Q285982', 'display_name': 'Endogeny', 'level': 2, 'score': 0.554286}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.5478225}, {'id': 'https://openalex.org/C2777468819', 'wikidata': 'https://www.wikidata.org/wiki/Q173670', 'display_name': 'Arginine', 'level': 3, 'score': 0.5063976}, {'id': 'https://openalex.org/C2777622882', 'wikidata': 'https://www.wikidata.org/wiki/Q417619', 'display_name': 'Nitric oxide synthase', 'level': 3, 'score': 0.49721125}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.30602902}, {'id': 'https://openalex.org/C2779234561', 'wikidata': 'https://www.wikidata.org/wiki/Q11995', 'display_name': 'Pregnancy', 'level': 2, 'score': 0.2814928}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.15785283}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.15376845}, {'id': 'https://openalex.org/C515207424', 'wikidata': 'https://www.wikidata.org/wiki/Q8066', 'display_name': 'Amino acid', 'level': 2, 'score': 0.049354136}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001120', 'descriptor_name': 'Arginine', 'qualifier_ui': 'Q000031', 'qualifier_name': 'analogs & derivatives', 'is_major_topic': True}, {'descriptor_ui': 'D004730', 'descriptor_name': 'Endothelium, Vascular', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D009569', 'descriptor_name': 'Nitric Oxide', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': True}, {'descriptor_ui': 'D019001', 'descriptor_name': 'Nitric Oxide Synthase', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': True}, {'descriptor_ui': 'D011225', 'descriptor_name': 'Pre-Eclampsia', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000581', 'descriptor_name': 'Amidohydrolases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000581', 'descriptor_name': 'Amidohydrolases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D001120', 'descriptor_name': 'Arginine', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D001120', 'descriptor_name': 'Arginine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001120', 'descriptor_name': 'Arginine', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D004730', 'descriptor_name': 'Endothelium, Vascular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009569', 'descriptor_name': 'Nitric Oxide', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009569', 'descriptor_name': 'Nitric Oxide', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D019001', 'descriptor_name': 'Nitric Oxide Synthase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D021041', 'descriptor_name': 'Placental Circulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011225', 'descriptor_name': 'Pre-Eclampsia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011225', 'descriptor_name': 'Pre-Eclampsia', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': False}, {'descriptor_ui': 'D011247', 'descriptor_name': 'Pregnancy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014599', 'descriptor_name': 'Uterus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014599', 'descriptor_name': 'Uterus', 'qualifier_ui': 'Q000098', 'qualifier_name': 'blood supply', 'is_major_topic': False}, {'descriptor_ui': 'D014664', 'descriptor_name': 'Vasodilation', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D014664', 'descriptor_name': 'Vasodilation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1080/14767050600852171', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S1605907', 'display_name': 'The Journal of Maternal-Fetal & Neonatal Medicine', 'issn_l': '1476-4954', 'issn': ['1476-4954', '1476-7058'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320449', 'host_organization_name': 'Informa', 'host_organization_lineage': ['https://openalex.org/P4310320449'], 'host_organization_lineage_names': ['Informa'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/16966108', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.81, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 31, 'referenced_works': ['https://openalex.org/W1507244839', 'https://openalex.org/W1858680866', 'https://openalex.org/W1952735225', 'https://openalex.org/W1963747418', 'https://openalex.org/W1970798352', 'https://openalex.org/W1975190260', 'https://openalex.org/W1978007486', 'https://openalex.org/W1980130144', 'https://openalex.org/W1982512200', 'https://openalex.org/W1999895172', 'https://openalex.org/W2019818970', 'https://openalex.org/W2023492147', 'https://openalex.org/W2029094496', 'https://openalex.org/W2048037659', 'https://openalex.org/W2049225913', 'https://openalex.org/W2057431680', 'https://openalex.org/W2066583469', 'https://openalex.org/W2076680300', 'https://openalex.org/W2098143325', 'https://openalex.org/W2104168812', 'https://openalex.org/W2104732966', 'https://openalex.org/W2129050578', 'https://openalex.org/W2145183598', 'https://openalex.org/W2148272382', 'https://openalex.org/W2151366734', 'https://openalex.org/W2169890089', 'https://openalex.org/W2283653792', 'https://openalex.org/W3160565403', 'https://openalex.org/W4231690758', 'https://openalex.org/W4244433662', 'https://openalex.org/W4250610556'], 'related_works': ['https://openalex.org/W2748952813', 'https://openalex.org/W2380540567', 'https://openalex.org/W2328664855', 'https://openalex.org/W2153125904', 'https://openalex.org/W2045993936', 'https://openalex.org/W2028156129', 'https://openalex.org/W2027748287', 'https://openalex.org/W2010799584', 'https://openalex.org/W1982094574', 'https://openalex.org/W1970739379'], 'abstract_inverted_index': {'Nitric': [0], 'oxide': [1], '(NO)': [2], 'is': [3, 8, 23], 'a': [4, 48, 88], 'potent': [5], 'vasodilator.': [6], 'NO': [7, 11], 'synthesized': [9], 'by': [10, 18, 25], 'synthases': [12], '(NOS)': [13], 'and': [14, 29, 53], 'NOS': [15], 'are': [16, 75], 'inhibited': [17], 'asymmetrical': [19], 'dimethylarginine': [20, 26], '(ADMA).': [21], 'ADMA': [22, 35, 46, 63, 71, 86], 'metabolized': [24], 'dimethylaminohydrolase': [27], '(DDAH)': [28], 'excreted': [30], 'in': [31, 37, 50, 62, 65, 73, 90], 'the': [32, 91], 'kidneys.': [33], 'Lower': [34], 'levels': [36, 64, 72], 'pregnant': [38], 'women': [39], 'compared': [40], 'to': [41], 'non-pregnant': [42], 'controls': [43], 'suggest': [44, 84], 'that': [45, 85], 'has': [47, 87], 'role': [49, 89], 'vascular': [51], 'dilatation': [52], 'blood': [54], 'pressure': [55], 'changes.': [56], 'Several': [57], 'studies': [58], 'show': [59], 'an': [60], 'increase': [61], 'pregnancies': [66], 'complicated': [67], 'with': [68], 'preeclampsia.': [69, 94], 'Elevated': [70], 'preeclampsia': [74], 'seen': [76], 'before': [77], 'clinical': [78], 'symptoms': [79], 'have': [80], 'developed;': [81], 'these': [82], 'findings': [83], 'pathogenesis': [92], 'of': [93]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1992957599', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2024-09-17T15:08:06.369642', 'created_date': '2016-06-24'}