Microarray analysis of the global gene expression profile following hypothermia and transient focal cerebral ischemia

Name: Work Video:
Duration: 3 min 30 s
Simon Nagel; Michalis Papadakis; K. Pfleger; C. Grond-Ginsbach; Alastair M. Buchan; Simone Wagner
{'id': 'https://openalex.org/W1992471985', 'doi': 'https://doi.org/10.1016/j.neuroscience.2012.01.048', 'title': 'Microarray analysis of the global gene expression profile following hypothermia and transient focal cerebral ischemia', 'display_name': 'Microarray analysis of the global gene expression profile following hypothermia and transient focal cerebral ischemia', 'publication_year': 2012, 'publication_date': '2012-02-10', 'ids': {'openalex': 'https://openalex.org/W1992471985', 'doi': 'https://doi.org/10.1016/j.neuroscience.2012.01.048', 'mag': '1992471985', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/22366221'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.neuroscience.2012.01.048', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S30122339', 'display_name': 'Neuroscience', 'issn_l': '0306-4522', 'issn': ['0306-4522', '1873-7544'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5081012111', 'display_name': 'Simon Nagel', 'orcid': 'https://orcid.org/0000-0003-2471-6647'}, 'institutions': [{'id': 'https://openalex.org/I223822909', 'display_name': 'Heidelberg University', 'ror': 'https://ror.org/038t36y30', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I223822909']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'S. Nagel', 'raw_affiliation_strings': ['Dept of Neurology, Univ of Heidelberg, Heidelberg, Germany'], 'affiliations': [{'raw_affiliation_string': 'Dept of Neurology, Univ of Heidelberg, Heidelberg, Germany', 'institution_ids': ['https://openalex.org/I223822909']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113568483', 'display_name': 'Michalis Papadakis', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I40120149', 'display_name': 'University of Oxford', 'ror': 'https://ror.org/052gg0110', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I40120149']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'M. Papadakis', 'raw_affiliation_strings': ['Acute Stroke Programme, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.'], 'affiliations': [{'raw_affiliation_string': 'Acute Stroke Programme, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.', 'institution_ids': ['https://openalex.org/I40120149']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5020823732', 'display_name': 'K. Pfleger', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I223822909', 'display_name': 'Heidelberg University', 'ror': 'https://ror.org/038t36y30', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I223822909']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'K. Pfleger', 'raw_affiliation_strings': ['Dept of Neurology, Univ of Heidelberg, Heidelberg, Germany'], 'affiliations': [{'raw_affiliation_string': 'Dept of Neurology, Univ of Heidelberg, Heidelberg, Germany', 'institution_ids': ['https://openalex.org/I223822909']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050591756', 'display_name': 'C. Grond-Ginsbach', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I223822909', 'display_name': 'Heidelberg University', 'ror': 'https://ror.org/038t36y30', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I223822909']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'C. Grond-Ginsbach', 'raw_affiliation_strings': ['Dept of Neurology, Univ of Heidelberg, Heidelberg, Germany'], 'affiliations': [{'raw_affiliation_string': 'Dept of Neurology, Univ of Heidelberg, Heidelberg, Germany', 'institution_ids': ['https://openalex.org/I223822909']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5012848561', 'display_name': 'Alastair M. Buchan', 'orcid': 'https://orcid.org/0000-0002-2918-5200'}, 'institutions': [{'id': 'https://openalex.org/I40120149', 'display_name': 'University of Oxford', 'ror': 'https://ror.org/052gg0110', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I40120149']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'A.M. Buchan', 'raw_affiliation_strings': ['Acute Stroke Programme, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.'], 'affiliations': [{'raw_affiliation_string': 'Acute Stroke Programme, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.', 'institution_ids': ['https://openalex.org/I40120149']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5029522651', 'display_name': 'Simone Wagner', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I223822909', 'display_name': 'Heidelberg University', 'ror': 'https://ror.org/038t36y30', 'country_code': 'DE', 'type': 'education', 'lineage': ['https://openalex.org/I223822909']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'S. Wagner', 'raw_affiliation_strings': ['Dept of Neurology, Univ of Heidelberg, Heidelberg, Germany'], 'affiliations': [{'raw_affiliation_string': 'Dept of Neurology, Univ of Heidelberg, Heidelberg, Germany', 'institution_ids': ['https://openalex.org/I223822909']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3000, 'currency': 'USD', 'value_usd': 3000, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 4.041, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 31, 'citation_normalized_percentile': {'value': 0.853941, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 92, 'max': 93}, 'biblio': {'volume': '208', 'issue': None, 'first_page': '109', 'last_page': '122'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11861', 'display_name': 'Thermal Regulation in Medicine', 'score': 0.9924, 'subfield': {'id': 'https://openalex.org/subfields/2706', 'display_name': 'Critical Care and Intensive Care Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11861', 'display_name': 'Thermal Regulation in Medicine', 'score': 0.9924, 'subfield': {'id': 'https://openalex.org/subfields/2706', 'display_name': 'Critical Care and Intensive Care Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11184', 'display_name': 'Neonatal and fetal brain pathology', 'score': 0.9893, 'subfield': {'id': 'https://openalex.org/subfields/2735', 'display_name': 'Pediatrics, Perinatology and Child Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10062', 'display_name': 'MicroRNA in disease regulation', 'score': 0.9874, 'subfield': {'id': 'https://openalex.org/subfields/1306', 'display_name': 'Cancer Research'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/transient', 'display_name': 'Transient (computer programming)', 'score': 0.523171}], 'concepts': [{'id': 'https://openalex.org/C2777390192', 'wikidata': 'https://www.wikidata.org/wiki/Q1036696', 'display_name': 'Hypothermia', 'level': 2, 'score': 0.7529366}, {'id': 'https://openalex.org/C541997718', 'wikidata': 'https://www.wikidata.org/wiki/Q188151', 'display_name': 'Ischemia', 'level': 2, 'score': 0.67642957}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.5911291}, {'id': 'https://openalex.org/C2780799671', 'wikidata': 'https://www.wikidata.org/wiki/Q17087362', 'display_name': 'Transient (computer programming)', 'level': 2, 'score': 0.523171}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.5157876}, {'id': 'https://openalex.org/C186836561', 'wikidata': 'https://www.wikidata.org/wiki/Q1931516', 'display_name': 'Microarray', 'level': 4, 'score': 0.47302318}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.43527317}, {'id': 'https://openalex.org/C8415881', 'wikidata': 'https://www.wikidata.org/wiki/Q6839217', 'display_name': 'Microarray analysis techniques', 'level': 4, 'score': 0.41607147}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.3541475}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.35030615}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.23724562}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.1907742}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.16033995}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.06485435}, {'id': 'https://openalex.org/C111919701', 'wikidata': 'https://www.wikidata.org/wiki/Q9135', 'display_name': 'Operating system', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D007036', 'descriptor_name': 'Hypothermia, Induced', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D002546', 'descriptor_name': 'Ischemic Attack, Transient', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D002546', 'descriptor_name': 'Ischemic Attack, Transient', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D017209', 'descriptor_name': 'Apoptosis', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D001831', 'descriptor_name': 'Body Temperature', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001831', 'descriptor_name': 'Body Temperature', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D030541', 'descriptor_name': 'Databases, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015536', 'descriptor_name': 'Down-Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015536', 'descriptor_name': 'Down-Regulation', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D015536', 'descriptor_name': 'Down-Regulation', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D020869', 'descriptor_name': 'Gene Expression Profiling', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006439', 'descriptor_name': 'Hemodynamics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006439', 'descriptor_name': 'Hemodynamics', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D020244', 'descriptor_name': 'Infarction, Middle Cerebral Artery', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020244', 'descriptor_name': 'Infarction, Middle Cerebral Artery', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D020244', 'descriptor_name': 'Infarction, Middle Cerebral Artery', 'qualifier_ui': 'Q000401', 'qualifier_name': 'mortality', 'is_major_topic': False}, {'descriptor_ui': 'D002546', 'descriptor_name': 'Ischemic Attack, Transient', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002546', 'descriptor_name': 'Ischemic Attack, Transient', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D008279', 'descriptor_name': 'Magnetic Resonance Imaging', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D046228', 'descriptor_name': 'Microarray Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009434', 'descriptor_name': 'Neural Pathways', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009434', 'descriptor_name': 'Neural Pathways', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}, {'descriptor_ui': 'D012313', 'descriptor_name': 'RNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012313', 'descriptor_name': 'RNA', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D012313', 'descriptor_name': 'RNA', 'qualifier_ui': 'Q000302', 'qualifier_name': 'isolation & purification', 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017208', 'descriptor_name': 'Rats, Wistar', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D060888', 'descriptor_name': 'Real-Time Polymerase Chain Reaction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015424', 'descriptor_name': 'Reperfusion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015203', 'descriptor_name': 'Reproducibility of Results', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012984', 'descriptor_name': 'Software', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015854', 'descriptor_name': 'Up-Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015854', 'descriptor_name': 'Up-Regulation', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D015854', 'descriptor_name': 'Up-Regulation', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.neuroscience.2012.01.048', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S30122339', 'display_name': 'Neuroscience', 'issn_l': '0306-4522', 'issn': ['0306-4522', '1873-7544'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/22366221', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.66, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 51, 'referenced_works': ['https://openalex.org/W1481246627', 'https://openalex.org/W1596431542', 'https://openalex.org/W1605936700', 'https://openalex.org/W1714706046', 'https://openalex.org/W1968898717', 'https://openalex.org/W1969637904', 'https://openalex.org/W1974394119', 'https://openalex.org/W1984377219', 'https://openalex.org/W1994623513', 'https://openalex.org/W1996618266', 'https://openalex.org/W1997915675', 'https://openalex.org/W1999112375', 'https://openalex.org/W2006485862', 'https://openalex.org/W2009267595', 'https://openalex.org/W2011316402', 'https://openalex.org/W2012342199', 'https://openalex.org/W2012775138', 'https://openalex.org/W2013320221', 'https://openalex.org/W2013900800', 'https://openalex.org/W2014844672', 'https://openalex.org/W2016478963', 'https://openalex.org/W2020962929', 'https://openalex.org/W2023595042', 'https://openalex.org/W2026473326', 'https://openalex.org/W2029070849', 'https://openalex.org/W2029568919', 'https://openalex.org/W2032464427', 'https://openalex.org/W2039650042', 'https://openalex.org/W2042189473', 'https://openalex.org/W2051192868', 'https://openalex.org/W2060095764', 'https://openalex.org/W2062642814', 'https://openalex.org/W2068729872', 'https://openalex.org/W2071469976', 'https://openalex.org/W2076989870', 'https://openalex.org/W2079144493', 'https://openalex.org/W2080975846', 'https://openalex.org/W2094182725', 'https://openalex.org/W2095865083', 'https://openalex.org/W2107369553', 'https://openalex.org/W2112505121', 'https://openalex.org/W2114377394', 'https://openalex.org/W2121209735', 'https://openalex.org/W2126261580', 'https://openalex.org/W2135752030', 'https://openalex.org/W2142844897', 'https://openalex.org/W2144025192', 'https://openalex.org/W2148309708', 'https://openalex.org/W2164127547', 'https://openalex.org/W2165730202', 'https://openalex.org/W2169712780'], 'related_works': ['https://openalex.org/W3152114242', 'https://openalex.org/W2911678823', 'https://openalex.org/W2796636403', 'https://openalex.org/W2767847608', 'https://openalex.org/W2364565895', 'https://openalex.org/W2319154570', 'https://openalex.org/W2152648570', 'https://openalex.org/W2043773466', 'https://openalex.org/W2037892364', 'https://openalex.org/W2015700328'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W1992471985', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 7}, {'year': 2014, 'cited_by_count': 5}, {'year': 2013, 'cited_by_count': 6}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-09T03:34:01.007270', 'created_date': '2016-06-24'}
Publication Information

Basic Information

Access and Citation

AI Researcher Chatbot

Primary Location

Authors

Topics

Keywords

Related Works
