Title: Peripheral dopamine receptor subtypes — a closer look
Abstract: Over the past two decades, two distinct groups of dopamine receptors have been identified in peripheral tissues, particularly those of the cardiovascular and autonomic nervous systems. The receptors can easily be distinguished from each other by the use of highly potent and selective agonists, such as N,N-di-n-propyl-5,6-ADTN and N,N-diethyl dopamine, and antagonists, such as domperidone and SCH 23390. The counterparts of each of these receptor types can be found in the CNS. However, as A. Hilditch and G. Drew explain, the atypical profiles of action of some agonists and antagonists suggest that two subtypes of each broad receptor group of peripheral dopamine receptors may exist.
Publication Year: 1985
Publication Date: 1985-01-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 51
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